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Ras

Ras

Ras is a family of related proteins which is expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal transduction). Ras is the prototypical member of the Ras superfamily of proteins, which are all related in 3D structure and regulate diverse cell behaviours.
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Cat. No. Product Name CAS No. Purity Chemical Structure
T72084 (R)-BI-2852
化合物T72084
2375482-49-6 98%
(R)-5-hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one 可用作RAS 家族蛋白的抑制剂 ,是治疗和预防肿瘤的化合物。 (R)...
T30778 CCG-257081
化合物CCG-257081
1922098-90-5 98%
CCG-257081 是心肌素相关转录因子和血清反应因子 (MRTF/SRF) 的抑制剂,通过抑制 Rho/MRTF/SRF 通路来发挥作用。CCG-257081已在多个小鼠模型中显示出预防博莱霉素诱导的纤维化的功效。CCG-257081 可用于预防癌症和纤维化的研究。
T1931 6H05
化合物6H05
1469338-01-9 98%
6H05 是致癌突变体 K-Ras(G12C) 的选择性变构抑制剂。
T62228 KRAS G12D inhibitor 14
KRAS G12D抑制剂14
2765254-39-3 98%
KRAS G12D inhibitor 14 是一种 KRAS G12D 的有效抑制剂,能够结合 KRAS G12D 蛋白 (Kd: 33 nM)。KRAS G12D inhibitor 14 抑制 KRAS G12D (KRAS G12D-GTP) 的活性形式,但对 KRAS G13D 无抑制作用。
T10374 ARS-1323-alkyne
化合物ARS-1323-alkyne
2436544-27-1 98%
ARS-1323-alkyne 是switch-II pocket (S-IIP)抑制剂,能够特异性报告活体细胞中 KRASG12C 核苷酸的状态。
T11770 KRAS G12C inhibitor 16
化合物 T11770
2349392-79-4 98%
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.
T11776 KRas G12C inhibitor 1
化合物 T11776
2158297-28-8 98%
KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
T11773 KRAS inhibitor-6
化合物 T11773
2022986-61-2 98%
KRAS inhibitor-6 is a potent KRAS G12C inhibitor.
T16023 MC 976
化合物 T16023
129831-99-8 98%
MC 976 is a derivative of Vitamin D3.
T11769 KRAS G12C inhibitor 15
化合物 T11769
2349393-21-9 98%
KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .
T11775 KRAS inhibitor-8
化合物 T11775
2022986-70-3 98%
KRAS inhibitor-8 is a potent KRAS G12C inhibitor.
T12452 Digeranyl bisphosphonate
化合物Digeranyl bisphosphonate
878143-03-4 98%
Digeranyl bisphosphonate 是一种有效的香叶基焦磷酸香叶酯 (GGPP) 合酶抑制剂,对 Rac1 的香叶基焦磷酸化有抑制作用。Digeranyl bisphosphonate 诱导细胞发生自噬却不诱导细胞凋亡。
T11771 KRAS G12C inhibitor 17
化合物 T11771
2349393-04-8 98%
KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.
T11767 KRAS G12C inhibitor 13
化合物 T11767
2241719-75-3 98%
KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .
T11774 KRAS inhibitor-7
化合物 T11774
2022986-68-9 98%
KRAS inhibitor-7 is a potent KRAS G12C inhibitor.
T11768 KRAS G12C inhibitor 14
化合物 T11768
2349393-95-7 98%
KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂(IC50= 18 nM)。
T11780 KRAS G12C inhibitor 5
化合物 T11780
2158297-63-1 98%
KRAS G12C inhibitor 5 is a KRas G12C inhibitor.
T11744 KB-5246
化合物 T11744
119474-55-4 98%
KB-5246, displays antibacterial activities.is a tetracyclic quinolone.
T11778 KRas G12C inhibitor 3
化合物 T11778
2206735-75-1 98%
KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.
T13844 PROTAC K-Ras Degrader-1
化合物 T13844
2378258-52-5 98%
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
(R)-BI-2852
T72084
(R)-5-hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one 可用作RAS 家族蛋白的抑制剂 ,是治疗和预防肿瘤的化合物。 (R)...
CCG-257081
T30778
CCG-257081 是心肌素相关转录因子和血清反应因子 (MRTF/SRF) 的抑制剂,通过抑制 Rho/MRTF/SRF 通路来发挥作用。CCG-257081已在多个小鼠模型中显示出预防博莱霉素诱导的纤维化的功效。CCG-257081 可用于预防癌症和纤维化的研究。
6H05
T1931
6H05 是致癌突变体 K-Ras(G12C) 的选择性变构抑制剂。
KRAS G12D inhibitor 14
T62228
KRAS G12D inhibitor 14 是一种 KRAS G12D 的有效抑制剂,能够结合 KRAS G12D 蛋白 (Kd: 33 nM)。KRAS G12D inhibitor 14 抑制 KRAS G12D (KRAS G12D-GTP) 的活性形式,但对 KRAS G13D 无抑制作用。
ARS-1323-alkyne
T10374
ARS-1323-alkyne 是switch-II pocket (S-IIP)抑制剂,能够特异性报告活体细胞中 KRASG12C 核苷酸的状态。
KRAS G12C inhibitor 16
T11770
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.
KRas G12C inhibitor 1
T11776
KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
KRAS inhibitor-6
T11773
KRAS inhibitor-6 is a potent KRAS G12C inhibitor.
MC 976
T16023
MC 976 is a derivative of Vitamin D3.
KRAS G12C inhibitor 15
T11769
KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .
KRAS inhibitor-8
T11775
KRAS inhibitor-8 is a potent KRAS G12C inhibitor.
Digeranyl bisphosphonate
T12452
Digeranyl bisphosphonate 是一种有效的香叶基焦磷酸香叶酯 (GGPP) 合酶抑制剂,对 Rac1 的香叶基焦磷酸化有抑制作用。Digeranyl bisphosphonate 诱导细胞发生自噬却不诱导细胞凋亡。
KRAS G12C inhibitor 17
T11771
KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.
KRAS G12C inhibitor 13
T11767
KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .
KRAS inhibitor-7
T11774
KRAS inhibitor-7 is a potent KRAS G12C inhibitor.
KRAS G12C inhibitor 14
T11768
KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂(IC50= 18 nM)。
KRAS G12C inhibitor 5
T11780
KRAS G12C inhibitor 5 is a KRas G12C inhibitor.
KB-5246
T11744
KB-5246, displays antibacterial activities.is a tetracyclic quinolone.
KRas G12C inhibitor 3
T11778
KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.
PROTAC K-Ras Degrader-1
T13844
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
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