Ras

Ras is a family of related proteins which is expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal transduction). Ras is the prototypical member of the Ras superfamily of proteins, which are all related in 3D structure and regulate diverse cell behaviours.

Cat. No.	Product Name	CAS No.	Purity
T72084	(R)-BI-2852 化合物T72084	2375482-49-6	98%
T72084	(R)-5-hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one 可用作RAS 家族蛋白的抑制剂，是治疗和预防肿瘤的化合物。 (R)...
T30778	CCG-257081 化合物CCG-257081	1922098-90-5	98%
T30778	CCG-257081 是心肌素相关转录因子和血清反应因子 (MRTF/SRF) 的抑制剂,通过抑制 Rho/MRTF/SRF 通路来发挥作用。CCG-257081已在多个小鼠模型中显示出预防博莱霉素诱导的纤维化的功效。CCG-257081 可用于预防癌症和纤维化的研究。
T1931	6H05 化合物6H05	1469338-01-9	98%
T1931	6H05 是致癌突变体 K-Ras(G12C) 的选择性变构抑制剂。
T62228	KRAS G12D inhibitor 14 KRAS G12D抑制剂14	2765254-39-3	98%
T62228	KRAS G12D inhibitor 14 是一种 KRAS G12D 的有效抑制剂，能够结合 KRAS G12D 蛋白 (Kd: 33 nM)。KRAS G12D inhibitor 14 抑制 KRAS G12D (KRAS G12D-GTP) 的活性形式，但对 KRAS G13D 无抑制作用。
T10374	ARS-1323-alkyne 化合物ARS-1323-alkyne	2436544-27-1	98%
T10374	ARS-1323-alkyne 是switch-II pocket (S-IIP)抑制剂，能够特异性报告活体细胞中 KRASG12C 核苷酸的状态。
T11770	KRAS G12C inhibitor 16 化合物 T11770	2349392-79-4	98%
T11770	KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.
T11776	KRas G12C inhibitor 1 化合物 T11776	2158297-28-8	98%
T11776	KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
T11773	KRAS inhibitor-6 化合物 T11773	2022986-61-2	98%
T11773	KRAS inhibitor-6 is a potent KRAS G12C inhibitor.
T16023	MC 976 化合物 T16023	129831-99-8	98%
T16023	MC 976 is a derivative of Vitamin D3.
T11769	KRAS G12C inhibitor 15 化合物 T11769	2349393-21-9	98%
T11769	KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .
T11775	KRAS inhibitor-8 化合物 T11775	2022986-70-3	98%
T11775	KRAS inhibitor-8 is a potent KRAS G12C inhibitor.
T12452	Digeranyl bisphosphonate 化合物Digeranyl bisphosphonate	878143-03-4	98%
T12452	Digeranyl bisphosphonate 是一种有效的香叶基焦磷酸香叶酯 (GGPP) 合酶抑制剂，对 Rac1 的香叶基焦磷酸化有抑制作用。Digeranyl bisphosphonate 诱导细胞发生自噬却不诱导细胞凋亡。
T11771	KRAS G12C inhibitor 17 化合物 T11771	2349393-04-8	98%
T11771	KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.
T11767	KRAS G12C inhibitor 13 化合物 T11767	2241719-75-3	98%
T11767	KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .
T11774	KRAS inhibitor-7 化合物 T11774	2022986-68-9	98%
T11774	KRAS inhibitor-7 is a potent KRAS G12C inhibitor.
T11768	KRAS G12C inhibitor 14 化合物 T11768	2349393-95-7	98%
T11768	KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂（IC50= 18 nM）。
T11780	KRAS G12C inhibitor 5 化合物 T11780	2158297-63-1	98%
T11780	KRAS G12C inhibitor 5 is a KRas G12C inhibitor.
T11744	KB-5246 化合物 T11744	119474-55-4	98%
T11744	KB-5246, displays antibacterial activities.is a tetracyclic quinolone.
T11778	KRas G12C inhibitor 3 化合物 T11778	2206735-75-1	98%
T11778	KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.
T13844	PROTAC K-Ras Degrader-1 化合物 T13844	2378258-52-5	98%
T13844	PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.