205
186
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122
Cat. No. | Product Name | ||
---|---|---|---|
L4800 | 血管生成库 | 1353 compounds | |
1353 个高潜力的抑制或促进血管生成的小分子集合,可用于药物靶点开发、血管生成机理研究的高通量筛选,高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0088 |
Angiotensin Receptor inhibitor kit
Angiotensin Receptor inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8560 |
Angiotensin II human acetate
Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate,血管紧张素II |
Apoptosis; RAAS | Apoptosis; Endocrinology/Hormones |
Angiotensin II human acetate (DRVYIHPF acetate) 是血管收缩剂,是肾素/血管紧张素系统的主要生物活性肽,在调节人类血压中起着核心作用。它刺激交感神经刺激,增加醛固酮生物合成和肾脏活动。它诱导血管平滑肌细胞生长,也诱导细胞凋亡。它通过 LOX-1 依赖的氧化还原敏感途径诱导内皮细胞毛细血管形成。 | |||
T7339 |
Angiotensin (1-7)
Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO |
RAAS; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性,因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮,是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大,并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。 | |||
T37596 |
Terevalefim
|
c-Met/HGFR | Tyrosine Kinase/Adaptors |
Terevalefim 是干细胞生长因子的一种类似物,对c-Met 受体有选择性激活作用。 | |||
TP1012 |
CH 5450
Z-Ile-Glu-Pro-Phe-Ome |
Others | Others |
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) 是一种人心脏糜酶 chymase 的短肽类抑制剂。 | |||
T71895 | MAC-5576 | ||
MAC-5576 a SARS-CoV-2 Protease inhibitor (IC50 = 81 nM). | |||
T78034 |
ANG1005
|
||
ANG1005是一种紫杉烷类衍生物,采用三个紫杉醇分子与Angiopep-2共价结合而成的脑穿透肽活性分子偶联物。此化合物设计用于利用低密度脂蛋白受体相关蛋白(LRP1)运输系统,穿透血脑和血脑脊髓屏障,进而作用于恶性细胞。 | |||
T1615 |
Irbesartan
厄贝沙坦,SR-47436,BMS-186295 |
Apoptosis; RAAS | Apoptosis; Endocrinology/Hormones |
Irbesartan (SR-47436) 是一种 1 型血管紧张素 II 受体拮抗剂,IC50为1.3 nM。 | |||
T7577 |
Angiotensin III, human, mouse
血管紧张素III,Angiotensin III, human, mouse(3TFA) |
RAAS | Endocrinology/Hormones |
Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA)) 是一种七肽,是血管紧张素 2 型受体 (AT2R) 激动剂,能够作用于 AT2R (IC50:0.648 nM)及 AT1R (IC50:21.1nM)。 | |||
T30663 |
Orange I
Orange I, sodium salt,Tertracid Orange I,α-Naphthol Orange,C.I. Acid Orange 20 |
||
Orange I (α-Naphthol Orange) 是一种芳香磺基对偶氮染料,可干扰微生物降解。 | |||
TP1528 |
Angiotensin I/II (1-5)
Angiotensin I/II 1-5 |
RAAS; Others | Endocrinology/Hormones; Others |
Angiotensin I/II (1-5) 是由血管紧张素 I/II 肽转化而来,有 1-5 个氨基酸组成的多肽。血管紧张素 I 是由肾素对血管紧张素原的作用形成的,血管紧张素 I 可产生血管紧张素 II 。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。 | |||
T7575L1 |
[Sar1, Ile8]-Angiotensin II acetate
|
RAAS | Endocrinology/Hormones |
[Sar1, Ile8]-Angiotensin II acetate 可激活 NADPH 和 NADH 氧化酶,并刺激血管平滑肌细胞中超氧阴离子的形成。 [Sar1, Ile8]-Angiotensin II acetate 对血管平滑肌有多种作用,包括正常动脉的收缩和培养细胞或病变血管的肥大或增生。 | |||
T7743 |
ANGIOTENSIN IV TFA(12676-15-2(free base))
|
RAAS | Endocrinology/Hormones |
ANGIOTENSIN IV TFA(12676-15-2(free base)) 是一种不太有效的血管紧张素 AT1 受体激动剂。 | |||
T21582L |
Acetyl Angiotensinogen (1-14), porcine Acetate
Acetyl Angiotensinogen (1-14), porcine Acetate(66641-26-7 Free base) |
Others | Others |
Acetyl Angiotensinogen (1-14), porcine Acetate 是一种肽,序列为 AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH。由血管紧张素原基因编码的蛋白质被称为前血管紧张素原或血管紧张素原前体。 | |||
T26629 |
Angstrom6
A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide |
PAI-1 | Metabolism |
Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽,它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性,能通过与 CD44 结合并调节 CD44 介导的细胞信号传导,抑制肿瘤细胞的迁移、侵袭和转移。 | |||
T40612 |
Manganese(salen) chloride
EUK-8 |
Others | Others |
Manganese(salen) chloride (EUK-8) 是超氧化物歧化酶和过氧化氢酶的一种模拟物,具有氧自由基清除性能。它可减轻内毒素血症猪的急性肺损伤。 | |||
T20760 |
Benzidine orange
DCC-1802,颜料橙13,Polymo Orange GR,Oralith Orange PG,DCC 1802,DCC1802 |
Others | Others |
Benzidine orange (DCC-1802) 具有致突变和致癌活性。 | |||
T7467 |
Acid orange 7
酸性橙 7,Orange II,D&,C Orange 4,COLIPA C015,2-naphthol orange,CI 15510 |
Others | Others |
Acid orange 7 (COLIPA C015) 是一种偶氮染料,是一种指示污染物。它大多存在于在纺织,食品和化妆品工业产生的制造废水中。 | |||
T7575L |
[Sar1, Ile8]-Angiotensin II 3TFA
[Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base)) |
Others | Others |
[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) 是一种对血管平滑肌具有多种作用的肽。 | |||
TP1842L |
Angiotensinogen (1-14), human acetate
|
Endogenous Metabolite | Metabolism |
Angiotensinogen (1-14), human acetate 是血管紧张素原的片段,它是肾素-血管紧张素系统的被动底物。 | |||
T14118 |
Acridine Orange hydrochloride
吖啶橙,3,6-双(二甲基氨基)吖啶 |
Others | Others |
Acridine Orange hydrochloride 是可透过细胞的荧光染料。 它与核酸结合,导致光谱发射发生改变。它被用作超活体染色剂和荧光细胞化学。 它可能导致微生物发生突变。 | |||
T19065 |
Thiazole Orange
|
Others | Others |
Thiazole Orange 是不对称的花青素染料,能够与寡核苷酸偶联,制备荧光杂交探针。它可用于分析网织红细胞。 | |||
TP2446L |
Angiotensin amide acetate
血管紧张素胺,Angiotensin amide acetate(53-73-6 Free base) |
Others | Others |
Angiotensin amide acetate 是Angiotensin amide 的衍生物。Angiotensin amide 是一种八肽酰胺,可以通过血管收缩来提高血压。 | |||
TP1295 |
Angiotensin I (human, mouse, rat)
Angiotensin 1 Human,血管紧张素 1 (人) |
Others | Others |
Angiotensin I (human, mouse, rat) 是血管紧张素Ⅱ的前体物质,在血管紧张素转化酶 (ACE) 的参与下裂解成血管紧张素Ⅱ。 | |||
T22574L |
Angiotensin 1/2 (5-7) acetate
|
RAAS | Endocrinology/Hormones |
Angiotensin 1/2 (5-7) acetate 是一种具有 H2N-Ile-His-Pro-OH 序列的肽。血管紧张素是一种寡肽,是一种激素和一种强大的双肽原。它来源于前体分子血管紧张素原,一种在肝脏中产生的血清球蛋白。它在肾素-血管紧张素系统中起重要作用。 | |||
T5036 |
cangrelor tetrasodium
|
GPR; P2Y Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Cangrelor tetrasodium 是三磷酸腺苷类似物,是可逆的选择性血小板P2Y12拮抗剂,也是非特异性的GPR17拮抗剂。它直接阻断腺苷二磷酸诱导的血小板活化和聚集,具有迅速有效的抗血小板作用。 | |||
T7663L |
Angiotensin 1/2 (1-9) TFA(34273-12-6(free base))
|
Others | Others |
Angiotensin 1/2 (1-9) TFA(34273-12-6(free base)) 含有从血管紧张素 I/II 肽转化而来的氨基酸 1-9。 | |||
T35834L |
(Sar¹)-Angiotensin II acetate
|
RAAS | Endocrinology/Hormones |
(Sar¹)-Angiotensin II acetate 是血管紧张素 II 的类似物,是血管紧张素 AT1 受体的特异性激动剂。它与富含脑膜的颗粒结合,Kd 为 2.7 nM。它可以刺激胚胎鸡肌细胞中的蛋白质合成和细胞生长。 | |||
TP1579 |
Angiotensin I/II (1-6)
Angiotensin I/II 1-6 |
RAAS; Others | Endocrinology/Hormones; Others |
Angiotensin I/II (1-6) 是由血管紧张素 I/II 肽转化而来,含有 1-6 个氨基酸的多肽。血管紧张素 I 被血管紧张素转换酶水解,形成具有生物活性的血管紧张素 II。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。 | |||
T21708L |
Angiotensin 1/2 + A (2 - 8) Acetate
Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base) |
Others | Others |
Angiotensin 1/2 + A (2 - 8) Acetate 是一种血管收缩剂。 | |||
TP1017L |
Angiotensin II 5-valine TFA
Angiotensin II 5-valine TFA(58-49-1 free base) |
RAAS | Endocrinology/Hormones |
Angiotensin II 5-valine TFA 是血管紧张素受体的激动剂。 | |||
T76169 |
Angiotensin-converting enzyme
|
||
Angiotensin-converting enzyme (ACE)血管紧张素转换酶是一种二羧基肽酶,它将非活性的血管紧张素 I (Ang I) 转化为活性的 Ang II,并降解活性的缓激肽 (BK)。Angiotensin-converting enzyme 是一种有效的血管收缩剂,常用于生化研究。 | |||
T37495 |
Angiotensin (1-7) (acetate)
|
||
Angiotensin 1-7 (Ang-(1-7)) acetate 是RAS中的一种内源性七肽,具备心脏保护作用,主要表现为对心肌细胞的抗炎与抗纤维化活性。该化合物能抑制纯化的犬ACE活性(IC50=0.65 μM),通过降低ACE活性并促进一氧化氮释放,作为血管舒张调节的局部协同因子。此外,Angiotensin 1-7 acetate 可阻止血管紧张素Ⅱ诱发的平滑肌细胞增殖和肥大,同时对内皮细胞表现出抗血管生成和生长抑制作用。 | |||
T36906 | Nanangenine G | ||
Nanangenine G is a drimane sesquiterpene that has been found inAspergillus.1It is cytotoxic to NS-1 mouse myeloma cells (IC50= 47 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019) | |||
T124898 | Angustine | ||
T131613 | Byakangelicol (Biacangelicol) | ||
Byakangelicol (Biacangelicol) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131613。 | |||
T7348 |
Imisopasem manganese
M40403,伊米帕锰 |
Others | Others |
Imisopasem manganese (M40403) is a manganese superoxide MnSOD non-peptidyl mimetic. | |||
T36177 |
Angeli’s Salt
Angeli’s Salt,Sodium α-oxyhyponitrite |
||
Angeli’s salt is regarded as a classical nitroxyl (NO-) donor, but under certain conditions evolution of NO is also observed.1 It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2.3 minutes at 37°C (pH 7.4) to liberate 0.54 moles of NO per mole of parent compound.[1],[2] | |||
T75586 | Dendraspis Angusticeps Venom | ||
Dendraspis Angusticeps Venom(Eastern Green Mamba Venom)是从Dendraspis Angusticeps(绿曼巴蛇)中提取的蛇毒,其含有利钠肽和成束蛋白(抗胆碱酯酶毒素)。这种毒液能够增强乙酰胆碱的释放,并抑制苯甲酸奎宁环与毒蕈碱乙酰胆碱受体(mAChR)的结合。 | |||
T40076 |
Gersizangitide
|
||
Gersizangitide is an angiogenesis inhibitor. | |||
TP2168 |
Angiotensinogen (1-14), human TFA
|
Others | Others |
Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is a precursor for all angiotensin peptides. | |||
T5824 |
Angiotensin II (3-8), human
Angiotensin IV |
RAAS | Endocrinology/Hormones |
Angiotensin II (3-8), human 是活性稍弱的血管紧张素AT1受体激动剂。 | |||
T25087 |
Angiopeptin
血管抑肽,D-Nal-cys-tyr-trp-lys-val-cys-thr-NH2,Bim 23014 C |
||
Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries. | |||
T10322 |
Angiotensin III
|
Others | Others |
Angiotensin III is an agonist of angiotensin 1 (AT1) and AT2 receptor. | |||
T76042 |
Angiopeptin TFA
|
||
Angiopeptin TFA,一种生长抑素的环状八肽类似物,作为sst2/sst5受体部分激动剂,其IC50值为0.26 nM和6.92 nM。该化合物能够抑制生长激素释放及IGF-1(胰岛素样生长因子-1)的产生,同时抑制腺苷酸环化酶活性或刺激细胞外酸化。Angiopeptin TFA在冠状动脉粥样硬化的研究中显示出潜力。 | |||
T35588 |
Ganglioside GM3 Mixture (sodium salt)
|
||
Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functi... | |||
T36904 |
Nanangenine B
|
||
Nanangenine B is a drimane sesquiterpene that has been found inAspergillus.1It is active againstB. subtilis(IC50= 62 μg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50= 38 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019) | |||
T125031 |
5,6-Dihydroyangonin
|
||
5,6-Dihydroyangonin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125031。 | |||
T125192 |
Curryangine
|
||
Curryangine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125192。 | |||
T72727 |
Huanglongmycin N
|
||
Huanglongmycin N为DNA拓扑异构酶I (DNA topoisomerase I) 抑制剂,表现出EC50值为14 μM。 | |||
T71722 |
Angiogenesis inhibitor BT2
|
||
Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, angiogenesis, and inflammation, interacting with MEK1, suppressing retinal CD31, pERK, VCAM-1, and VEGF-A165 expression. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7040 |
Angiotensin II human
DRVYIHPF,Angiotensin II,Hypertensin II,血管紧张素Ⅱ,Ang II,血管紧张素II |
Apoptosis; RAAS | Apoptosis; Endocrinology/Hormones |
Angiotensin II human (Ang II) 是一种生物活性肽,一种血管收缩剂。Angiotensin II 可以与 AT1R 和 AT2R 相互作用,调节人类血压,刺激交感神经,增加醛固酮生物合成和肾脏活动。 | |||
TWS1293 |
Angelic anhydride
2-Methylisocrotonic Anhydride,当归酸酐,(Z)-2-Methylbut-2-enoic anhydride |
Others | Others |
Angelic anhydride ((Z)-2-Methylbut-2-enoic anhydride) 是一种脂肪酸酐,来自于不饱和碳氢酸酐。 | |||
T2809 |
(R)-Fangchinoline
防己醇灵,Thaligine,(+)-Thalrugosine,Demethyl tetrandrine |
FAK; Antibacterial; Antibiotic | Angiogenesis; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors |
(R)-Fangchinoline ((+)-Thalrugosine) 是一种来自Stephania 属的生物碱,具有抗菌和降血压活性。它可用作中药,可用于发烧,腹泻,消化不良和泌尿疾病的研究。 | |||
T3328 |
Angelic Acid
2-Methylisocrotonic acid,(Z)-2-Methylbut-2-enoic acid,当归酸,cis-2-Methyl-2-butenoic acid |
Others | Others |
Angelic Acid ((Z)-2-Methylbut-2-enoic acid) 是一种存在于Anthemis nobilis 精油中的酯,能够促进伤口愈合,具有促进安定和精神药物的作用。 | |||
T4S1616 |
Sanggenon D
桑根酮D,Sanggenone D |
NOS; COX; GABA Receptor | Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience |
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysaccharide (LPS)-induced RAW 264.7 ce | |||
T4S1615 |
Sanggenon C
桑根酮C,桑根酮 C,Sanggenone C |
NF-κB | NF-κB |
Sanggenon C (Sanggenone C) 是一种从桑属的根皮中分离得到的黄烷酮 Diels-Alder 加合物化合物。它可抑制NF-κB 活性,抑制 RAW264.7 细胞中诱导型一氧化氮合酶的表达,以及肿瘤坏死因子-α 刺激的细胞粘附和血管细胞粘附分子-1 的表达。 它具有抗氧化和抗炎作用,也有抑制胰脂肪酶作用。 | |||
T0129 |
Sanguinarine chloride
Pseudochelerythrine chloride,血根碱,氯化血根碱,Sanguinarium chloride |
Apoptosis; EGFR; VEGFR; Antibacterial; Parasite; Autophagy | Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors |
Sanguinarine chloride (Pseudochelerythrine chloride) 是一种来源于 Sanguinaria Canadensis 的生物碱,通过激活活性氧的产生,诱导细胞凋亡。 | |||
TN1019 |
Beta-mangostin
β-Mangostin,beta-倒捻子素 |
Apoptosis; Antibacterial; Parasite | Apoptosis; Microbiology/Virology |
Beta-mangostin (β-Mangostin) 是存在 Cratoxylum arborescens 中的一种氧杂蒽酮类天然产物,有抗癌和抗菌活性,对结核分枝杆菌的 MIC 值为 6.25 μg/mL。它在体外有抗疟活性,对恶性疟原虫的 IC50值为 3.00 μg/mL。 | |||
T2781 |
Sanguinarine
Sanguinarin,Pseudochelerythrine,血根碱 |
Apoptosis; Antioxidant; Autophagy | Apoptosis; Autophagy; oxidation-reduction |
Sanguinarine (Pseudochelerythrine) 是一种来源于血根草的生物碱,具有抗微生物、抗氧化和抗炎特性。 | |||
T5813 |
BYAKANGELICIN
|
Reductase | Endocrinology/Hormones; Metabolism |
Byakangelicin 是发现于当归根中的一种活性化合物,可作为调节剂,改善各种活性化合物 (Umb,Cur 和 Dox) 的脑积累,增强研究效果。它提高所有PXR 靶基因 (如MDR1) 的表达,并广泛的诱导药物-药物相互作用。它可抑制性激素的作用,可能会增加内源激素的分解代谢。 | |||
TN2130 |
Manghaslin
槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside |
AChE; Glucosidase | Metabolism; Neuroscience |
Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) 是具有抗炎活性的黄酮苷,对 AChE 具有抑制活性,IC50=94.92 µM。 | |||
T3903 |
Angoroside C
安格洛甙C,安格洛苷C |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Angoroside C 是一种苯丙苷,从 Radix Scrophulariae 中提取到,有益于心室重构。 | |||
T2842 |
Tangeretin
NSC53909,Tangeritin,NSC618905,桔皮素 |
Apoptosis; Gamma-secretase | Apoptosis; Neuroscience; Proteases/Proteasome; Stem Cells |
Tangeretin (NSC-618905) 是一种来自柑橘类水果果皮的类黄酮,是一种Notch-1抑制剂,具有抗炎,保护神经等作用。 | |||
TN1384 |
Angelicain
当归碱,去甲升麻素,Norcimifugin |
Others | Others |
Angelicain (Norcimifugin) 是升麻 (Cimicifuga foetida) 的一种具有抗炎作用的成分。 | |||
TN4943 |
Sanguisorbigenin
地榆皂苷元,Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid |
Antibacterial | Microbiology/Virology |
Sanguisorbigenin (Tomentosolic acid) 抑制耐甲氧西林金黄色葡萄球菌,是一种天然抗菌剂。 | |||
TN1557 |
Decursinol angelate
|
ERK; VEGFR; PKC; JNK | Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors |
Decursinol angelate 是从朝鲜当归根部分离得到的一种天然产物,是 PKC 激酶的激活剂,有细胞毒性,抗肿瘤和抗炎活性。 | |||
T3905 |
Isomangiferin
|
Free radical scavengers; Antiviral; Influenza Virus | Immunology/Inflammation; Microbiology/Virology; oxidation-reduction |
Isomangiferin 是一种天然产物,具有抗病毒的作用。它还具有抗氧化和自由基清除活性。 | |||
T4S2012 |
Dihydrosanguinarine
13,14-Dihydrosanguinarine,Dihydro Sanguinarine,二氢血根碱 |
Caspase; Antifungal | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
Dihydrosanguinarine 是榕树叶片提取出的一种天然产物,具有抗真菌和抗癌活性。 | |||
T2875 |
Angelicin
Isopsoralen,异补骨脂素 |
Apoptosis; Virus Protease; Antiviral | Apoptosis; Immunology/Inflammation; Microbiology/Virology |
Angelicin (Isopsoralen) 是一种三环芳烃天然产物,结构上跟补骨脂素有关,具有抗癌、抗炎、抗病毒等活性。 | |||
TN6739 |
Angoline
6-Methoxyldihydrochelerythrine |
IL Receptor; STAT | Immunology/Inflammation; JAK/STAT signaling; Stem Cells |
Angoline (6-Methoxyldihydrochelerythrine) 是选择性 IL6/STAT3信号通路的抑制剂,IC50为 11.56 μM。它抑制 STAT3 磷酸化及其靶基因表达,并抑制癌细胞增殖。 | |||
TN1018 |
Angeloylgomisin H
当归酰戈米辛 H,当归酰戈米辛H |
PPAR | DNA Damage/DNA Repair; Metabolism |
Angeloylgomisin H 是从五味子中提取的一种木脂素类天然产物。它通过激活PPAR-γ来改善胰岛素刺激的葡萄糖摄取潜力。 | |||
TQ0099 |
20-O-Acetylingenol-3-angelate
巨大戟醇-3-O-当归酸-20-乙酸酯,Euphorbia factor Pe1 |
Others | Others |
20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) 是一种天然化合物,存在于植物英加的叶子和茎中。它具有多种生物活性,包括抑制肿瘤生长、抗炎、抗真菌和抗氧化作用。 | |||
T7995 |
α-Angelica lactone
α-当归内酯,当归内酯,Alpha-Angelica Lactone |
Others; GST | Others; oxidation-reduction |
α-Angelica lactone 是一种乙烯基亲核试剂,也是一种天然存在的抗癌剂。它可以得到手性的 δ-氨基 γ,γ-二取代丁烯醇内酯羰基衍生物,并在 γ-碳上表现出亲电子俘获。它通过选择性增强谷胱甘肽-S-硫转移酶 (GST) 和 UDP-葡糖苷转移酶 (UGT) 解毒酶发挥强大的化学保护作用。 | |||
TN2546 |
1-Isomangostin
|
NF-κB | NF-κB |
1-Isomangostin 具有细胞毒性和抗补体活性。 | |||
TN1390 |
Angeloylgomisin Q
当归酰基戈米辛Q,当归酰戈米辛Q |
Others | Others |
Angeloylgomisin Q 是一种新二苯并环辛二烯类木脂素,提取自五味子茎中。它具有用于阿尔茨海默病研究的潜力。 | |||
TQ0316 |
Ingenol-5,20-acetonide-3-O-angelate
Ingenol 5,20-acetonide 3-angelate,Ingenol 3-angelate 5,20-acetonide,巨大戟醇-5,20-缩丙酮-3-当归酸酯 |
Others | Others |
Ingenol-5,20-acetonide-3-O-angelate (Ingenol 5,20-acetonide 3-angelate) 是一种天然产物。 | |||
TN7056 |
11-Methoxyyangonin
Trimethylhispidin,NSC212503,11-甲氧基醉椒素 |
Others | Others |
11-Methoxyyangonin (Trimethylhispidin) 是一种天然的卡瓦内酯。 | |||
T3668 |
Galangin
Norizalpinin,高良姜素,3,5,7-Trihydroxyflavone |
ERK; P450; NF-κB; Autophagy | Autophagy; MAPK; Metabolism; NF-κB |
Galangin (Norizalpinin) 是芳烃受体的激动剂/拮抗剂,并且还显示对 CYP1A1 活性的抑制作用。 | |||
T1717 |
alpha-Mangostin
α-倒捻子素,α-Mangostin,Mangostin |
Apoptosis; Virus Protease; Dehydrogenase; Reactive Oxygen Species; Antibacterial; Antifungal | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
alpha-Mangostin (Mangostin) 是有多种生物活性的膳食呫吨酮。它是一种IDH1突变体的抑制剂,Ki 值为 2.85 μM。 | |||
T2S1635 |
3-Isomangostin
|
MTH1 | DNA Damage/DNA Repair |
3-Isomangostin 可从莽吉柿壳中提取的一种天然产物,是一种乙酰胆碱酯酶选择性抑制剂,也是一种有效的人醛糖还原酶抑制剂,IC50 为 3.48 uM。它抑制 MutT 同源物 1 (MTH1),IC50 为 52 nM。它具有清除自由基、抗疟原虫和抗癌的活性。 | |||
T7024 |
Qingyangshengenin
青阳参甙元,Qingyangshengenin A,Cynanchagenin |
Others | Others |
Qingyangshengenin (Cynanchagenin) 是一种孕烷糖苷,是一种分离自Cychuchumot ophyllum(Asclepiadaceae) 的根中的 C21 类固醇糖苷配基。它具有抗癌作用。 | |||
T5S0734 |
Desmethoxyyangonin
Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain |
Others; Monoamine Oxidase | Neuroscience; Others |
Desmethoxyyangonin (5,6-Dehydrokavain) 是一种MAO-B 可逆性抑制剂。 | |||
TN1445 |
Bisabolangelone
|
p38 MAPK; MAPK | MAPK |
Bisabolangelone 是从没药中分离出来的一种倍半萜衍生物,具有抗炎作用。它通过阻断巨噬细胞内的NF-kappaB 和MAPK 通路抑制脂多糖刺激的炎症,具有抗溃疡作用。 | |||
T3S0738 |
yangonin
Y100550,甲氧醉椒素 |
Cannabinoid Receptor; NF-κB; Autophagy | Autophagy; GPCR/G Protein; NF-κB |
Yangonin (Y100550) 是一种新型 CB1 受体配体,对人重组 CB1 受体具有亲和力。它可能是干预 NF-κB 依赖性病理状况的候选药物。 | |||
T3804 |
Neomangiferin
Mangiferin 7-glucoside,新芒果苷 |
Phosphatase | Metabolism |
Neomangiferin (Mangiferin 7-glucoside) 是一种天然的 C-glucosyl xanthone,分离自干燥的Anemarrhena asphodeloides 的根茎中。它能够减轻大鼠高脂饮食诱导的非酒精性脂肪性肝病 (NAFLD)。 | |||
T5707 |
3-O-Methylgalangin
3-Methylgalangin,GALANGIN-3-METHYLETHER,高良姜素 3-O-甲醚,高良姜素-3-甲醚 |
Antibacterial | Microbiology/Virology |
3-O-Methylgalangin (GALANGIN-3-METHYLETHER) 是一种来源于高良姜根茎的天然黄酮,具有抗菌活性,抑制胰腺脂肪酶。 | |||
T8724 |
6-Methoxydihydrosanguinarine
|
Others | Others |
6-Methoxydihydrosanguinarine 是一种从M. cordata 果实中分离出的生物碱,它对 MCF-7 细胞系(IC50:0.61 μM)和 SF-268 细胞系(IC50:0.54 μM)具有强的细胞毒性。 | |||
T13354 |
Xanthoangelol
|
Apoptosis; Monoamine Transporter; Antibacterial; AMPK | Apoptosis; Chromatin/Epigenetic; Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling |
Xanthoangelol 可从 Angelica keiskei 中提取得到,对肥胖引起的炎症反应有抑制作用。Xanthoangelol 具有抗菌活性,对单胺氧化酶有抑制作用,还诱导神经母细胞瘤和白血病细胞凋亡。 | |||
T3012 |
Mangiferin
Alpizarin,Chinomin,芒果,Hedysarid |
Apoptosis; Others; NF-κB; Nrf2 | Apoptosis; Immunology/Inflammation; NF-κB; Others |
Mangiferin (Hedysarid) 是一种Nrf2激活剂。它抑制NF-κB 亚基p65和p50的核移位,具有抗氧化、抗糖尿病、抗高尿酸血症、抗病毒、抗癌和抗炎活性。 | |||
T3801 |
(Rac)-Byakangelicin
白当归素,Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin |
Others | Others |
(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) 是一种 Byakangelicin 的外消旋体,主要分离自 Angelica 属中。其中 Byakangelicin 是醛糖还原酶抑制剂(IC50:6.2 μM),可用作抗肿瘤剂。 | |||
T8152 |
6-Demethoxytangeretin
|
MAPK; ALK | Angiogenesis; MAPK; Tyrosine Kinase/Adaptors |
6-Demethoxytangeretin 是一种从柑橘分离的黄酮。它能够促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。它具有抗炎和抗过敏作用,通过间变性淋巴瘤激酶和丝裂原活化蛋白激酶途径抑制人肥大细胞中 IL-6 的产生和基因表达。 | |||
T9605 |
Sangivamycin
BA-90912,桑霉素,NSC 65346 |
Nucleoside Antimetabolite/Analog; PKC | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair |
Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。 | |||
TN4234 |
Hydrangenol
|
NOS; NF-κB; Nrf2; NO Synthase; Antifection; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology; NF-κB |
Hydrangenol 是一种天然产物,可从绣球花 (Hydrangea serrata) 的叶中分离。Hydrangenol 是口服有效的抗光老化化合物,可以预防皱纹的形成。Hydrangenol 可以降低 MMP 和炎症细胞因子的表达,增加保湿因子和抗氧化基因的水平。 | |||
T4S1637 |
gamma-Mangostin
Normangostin,γ-倒捻子素 |
Others; 5-HT Receptor | GPCR/G Protein; Neuroscience; Others |
gamma-Mangostin (Normangostin) 是从药用植物山竹的果壳中提纯的一种天然产物,是一种竞争性5-HT2A 受体拮抗剂。它是运甲状腺素蛋白原纤维化抑制剂,与甲状腺素结合位点结合并稳定了 TTR 四聚体,具有抗高血压、预防结肠癌等作用。 | |||
TN1305 |
Ethoxysanguinarine
乙氧基血根碱,6-Ethoxydihydrosanguinarine |
Apoptosis; AChR | Apoptosis; Neuroscience |
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) 是存在于龙葵中的一种苯并菲啶生物碱天然产物,通过抑制蛋白磷酸酶 2A,可抑制结直肠癌细胞活力,诱导细胞凋亡。 | |||
TN2322 |
Yangambin
|
Calcium Channel; PAFR | GPCR/G Protein; Membrane transporter/Ion channel; Metabolism |
Yangambin 是从诸如番荔枝科植物中分离出来的呋喃木脂素,是选择性PAF 受体拮抗剂,通过调控Ca2+通道抑制 Ca2+流入,导致 [Ca2+]i 在血管平滑肌细胞和随后的外周血管舒张中减少,具有降压作用。 | |||
TMS1461 |
Qingyangshengenin B
青阳参甙元B,青阳参苷元B,Otophylloside B |
Beta Amyloid | Neuroscience |
Qingyangshengenin B (Otophylloside B) 是一种分离自 Qingyangshen 的 C-21 甾体苷。它能够在 mRNA 水平上抑制 Aβ 的表达来减少 Aβ 的沉积,对 Aβ 的毒性有保护作用。它具有抗癫痫作用。 | |||
TN2027 |
Oxysanguinarine
8-Oxosanguinarine,氧化血根碱,Hydroxysanguinarine |
Parasite | Microbiology/Virology |
Oxysanguinarine (Hydroxysanguinarine) 是一种来自Meconopsis simplicifolia 的小檗生物碱,具有抗疟和抗血小板聚集活性,对登革热病毒具有潜在的抑制作用。 | |||
T3122 |
Fangchinoline
Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline |
Apoptosis; FAK; HIV Protease; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。 | |||
T6S0077 |
Byakangelicol
|
COX | Immunology/Inflammation; Neuroscience |
Byakangelicol 是一种分离自白芷的白三醇,能够抑制环加氧酶-2的表达及活性,从而减少白细胞介素-1β诱导的 A549 细胞中前列腺素 E2 的释放。它可用于研究气道炎症。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02474 |
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)
angiopoietin 2,Agpt2,Ang-2,Ang2 |
Mouse | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.5 kDa and the accession number is B9EHQ4. | |||
TMPH-00934 |
ANG Protein, Human, Recombinant (His)
RNase 5,ANG,Angiogenin,Ribonuclease 5 |
Human | E. coli |
ANG Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-00763 |
ANG Protein, Human, Recombinant
RNASE5,ANG,Angiogenin,Ribonuclease 5,血管生成素... |
Human | E. coli |
Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin... | |||
TMPH-02506 |
ANG Protein, Mouse, Recombinant (His)
ANG,Angiogenin,Ribonuclease 5,RNase 5 |
Mouse | E. coli |
ANG Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.9 kDa and the accession number is P21570. | |||
TMPY-02684 |
ANGPT4/Angiopoietin-4 Protein, Human, Recombinant (hFc)
angiopoietin 4,ANG4,ANG-3,AGP4 |
Human | HEK293 Cells |
ANGPT4/Angiopoietin-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.7 kDa and the accession number is Q9Y264. | |||
TMPJ-00303 |
ANG2 Protein, Mouse, Recombinant (hFc)
angiopoietin 2,Angiopoietin-2,ANG... |
Mouse | HEK293 Cells |
ANG2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is O35608. | |||
TMPJ-01435 |
ANG2 Protein, Rhesus macaque, Recombinant (hFc)
ANG-2,Angiopoietin-2,AGPT2,angiop... |
Rhesus | HEK293 Cells |
ANG2 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is XM_001097949. | |||
TMPY-03143 |
ANGPT4/Angiopoietin-4 Protein, Human, Recombinant (His)
angiopoietin 4,ANG-3,ANG4,AGP4 |
Human | HEK293 Cells |
ANGPT4/Angiopoietin-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.6 kDa and the accession number is A0A024R507. | |||
TMPH-00343 |
Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)
Angiopoietin-1,ANG-1,ANGPT1 |
Canine | HEK293 Cells |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) is expressed in HEK293 mammalian cells wi... | |||
TMPH-00479 |
Angiopoietin-1 Protein, Canine, Recombinant (His)
ANG-1,ANGPT1,Angiopoietin-1 |
Canine | Baculovirus Insect Cells |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with C-6... | |||
TMPH-03241 |
Angiopoietin-2 Protein, Rat, Recombinant (E. coli, His)
Angpt2,Angiopoietin-2,ANG-2 |
Rat | E. coli |
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Angiopoietin-2 Protein,... | |||
TMPY-04245 |
ANGPT1/Angiopoietin-1 Protein, Mouse, Recombinant (His)
angiopoietin 1,Ang1,1110046O21Rik,Ang<... |
Mouse | HEK293 Cells |
ANGPT1/Angiopoietin-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is O08538. | |||
TMPH-03240 |
Angiopoietin-2 Protein, Rat, Recombinant (His)
Angiopoietin-2,Angpt2,ANG-2 |
Rat | Baculovirus Insect Cells |
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Angiopoietin-2 Protein,... | |||
TMPH-00935 |
Angiopoietin-1 Protein, Human, Recombinant (His)
Angiopoietin-1,ANGPT1,ANG-1 |
Human | E. coli |
Angiopoietin-1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-05435 |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
angiopoietin 1,AGPT,AGP1,ANG1 |
Human | HEK293 Cells |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is Q15389-1. | |||
TMPK-01329 |
ANGPTL4 Protein, Cynomolgus, Recombinant (His)
PGAR,AGP4,NGPTL2,ANG4,ANGPTL4,pp1158,HFARP... |
Cynomolgus | HEK293 Cells |
Candidates for this common regulatory system include signals mediated by peroxisome proliferator-activated regulator and its response factor, angiopoietin-like 4. The expression and bioactivity of angiopoietin-like 4, an adipocytokine that was originally reported to have an angiogenic function, have been detected not only in the vascular system and adipose tissue but also in rheumatoid joints. | |||
TMPY-00664 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
Angiopoietin-2,AGPT2,angiopoietin 2,AN... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.6 kDa and the accession number is O15123-1. | |||
TMPY-05286 |
ANGPTL3 Protein, Human, Recombinant (His)
FHBL2,ANL3,ANGPT5,angiopoietin-like 3,... |
Human | Baculovirus Insect Cells |
ANGPTL3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.3 kDa and the accession number is Q9Y5C1. | |||
TMPH-03239 |
Angiopoietin-1 Protein, Rat, Recombinant (His)
ANG-1,ANGPT1,Angiopoietin-1 |
Rat | HEK293 Cells |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis ... | |||
TMPK-00285 |
ANGPTL3 Protein, Human, Recombinant (His & Avi), Biotinylated
ANGPTL3,FHBL2,ANGPT5,Angiopoietin... |
Human | HEK293 Cells |
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3... | |||
TMPJ-00286 |
ANGPTL3 Protein, Human, Recombinant (hFc)
ANGPTL3,ANGPT5,Angiopoietin-relat... |
Human | HEK293 Cells |
Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits ... | |||
TMPK-00284 |
ANGPTL3 Protein, Human, Recombinant (His & Avi)
FHBL2,Angiopoietin-like Protein 3,ANG-5, |
Human | HEK293 Cells |
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3... | |||
TMPK-00303 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi)
angiopoietin 2,angiopoietin-2a,ang |
Human | HEK293 Cells |
Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies.. | |||
TMPY-06613 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi), Biotinylated
ANG2,angiopoietin 2,Angiopoietin-... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.72 kDa and the accession number is NP_001138.1. | |||
TMPY-00083 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His)
ANG2,angiopoietin 2,AGPT2,Angiopo... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.8 kDa and the accession number is O15123-1. | |||
TMPY-05259 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His), Biotinylated
angiopoietin 2,Angiopoietin-2,AGPT2,AN... |
Human | CHO Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His), Biotinylated is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is O15123-1. | |||
TMPY-05360 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (mFc)
ANG2,AGPT2,Angiopoietin-2,angiopo... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 80.3 kDa and the accession number is O15123-1. | |||
TMPY-03955 |
Influenza A H7N9 (A/Shanghai/2/2013) Nucleoprotein/NP Protein (His)
NP Protein, H7N9 |
H7N9 | Baculovirus Insect Cells |
Influenza A H7N9 (A/Shanghai/2/2013) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.8 kDa and the accession number is A0A024E372. | |||
TMPY-05053 |
ANGPTL2 Protein, Human, Recombinant (His)
HARP,angiopoietin-like 2,ARP2 |
Human | HEK293 Cells |
ANGPTL2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is A0A024R868. | |||
TMPY-00416 |
Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin/HA0 Protein
Harvey rat sarcoma viral oncogene homolog |
H10N8 | Baculovirus Insect Cells |
Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin/HA0 Protein is expressed in Baculovirus insect cells. The predicted molecular weight is 60.6 kDa. | |||
TMPY-04168 |
ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)
angiopoietin 2 |
Cynomolgus,Rhesus | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is XP_005562586.1&XP_001097949.1. | |||
TMPY-05918 |
Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019)/(A/Hawaii/70/2019) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019)/(A/Hawaii/70/2019) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is A0A5Q2EZ09. | |||
TMPY-03523 |
ANGPTL4 Protein, Human, Recombinant (His)
NL2,HFARP,angiopoietin-like 4,ARP4,PGAR,FIAF,TGQTL,... |
Human | HEK293 Cells |
ANGPTL4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.5 kDa and the accession number is Q9BY76. | |||
TMPY-04090 |
Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His)
Harvey rat sarcoma viral oncogene homolog |
H7N9 | HEK293 Cells |
Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa. | |||
TMPY-06059 |
Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) Nucleoprotein/NP Protein (His)
NP Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.7 kDa. | |||
TMPY-02662 |
Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H10N8 | Baculovirus Insect Cells |
Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.9 kDa. | |||
TMPK-00298 |
ANGPTL2 Protein, Human, Recombinant (His & Avi)
ANGRP2,ANGPTL2,angiopoietin-like ... |
Human | HEK293 Cells |
Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers. ANGPTL2 Protein, ... | |||
TMPH-02507 |
Angiogenin-4 Protein, Mouse, Recombinant (His & Myc & SUMO)
EC:3.1.27.-,Angiogenin-4,Ang4 |
Mouse | E. coli |
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). Angiogenin-4 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-Myc tag. The predicted molecular weight is 31.4 kDa and the accession number is Q3TMQ6. | |||
TMPY-04591 |
Influenza A H5N8 (A/duck/Jiangsu/k1203/2010) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N8 | HEK293 Cells |
Influenza A H5N8 (A/duck/Jiangsu/k1203/2010) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.7 kDa and the accession number is M9NJD2. | |||
TMPY-04336 |
Orange fluorescent protein Protein, Discosoma sp, Recombinant (His)
OFP Protein |
Discosoma sp | E. coli |
OFPSparkTM is a red (orange) fluorescent protein (excitation/emission maxima are 549 and 566 nm, respectively) derived from DsRed. Possessing high photostability and pH stability, OFPSparkTM is more than twice brighter than mOrange2. Fast OFPSparkTM maturation makes it detectable in mammalian cells as early as within 8 hrs after transfection. OFPSparkTM can be expressed and detected in a wide range of organisms. Mammalian cells transiently transfected with OFPSparkTM expression vectors produce b... | |||
TMPH-02510 |
ANGPTL8 Protein, Mouse, Recombinant (His)
Rifl,Refeeding-induced fat and liver protein,Betatrophin, |
Mouse | P. pastoris (Yeast) |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage. According to another study, not required for cleavage of ANGPTL3. ANGPTL8 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.5 kDa and the... | |||
TMPY-03838 |
Influenza A H7N9 (A/Hangzhou/1/2013) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H7N9 | HEK293 Cells |
Influenza A H7N9 (A/Hangzhou/1/2013) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is M4YV75. | |||
TMPY-04678 |
Influenza A H5N6 (A/duck/Guangdong/GD01/2014) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N6 | Baculovirus Insect Cells |
Influenza A H5N6 (A/duck/Guangdong/GD01/2014) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.1 kDa and the accession number is A0A059XIJ9. | |||
TMPY-03998 |
ANGPTL2 Protein, Mouse, Recombinant (hFc)
Arp2,AI593246,AW260363,angiopoietin-like 2 |
Mouse | HEK293 Cells |
ANGPTL2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.5 kDa and the accession number is Q9R045. | |||
TMPY-06887 |
Influenza A H1N1 (A/Hawaii/70/2019;A/Guangdong-Maonan/SWL1536/2019) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Hawaii/70/2019;A/Guangdong-Maonan/SWL1536/2019) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.24 kDa. | |||
TMPY-00204 |
Influenza A H7N9 (A/Zhejiang/DTID-ZJU10/2013) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H7N9 | Baculovirus Insect Cells |
Influenza A H7N9 (A/Zhejiang/DTID-ZJU10/2013) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is U6A0I2. | |||
TMPY-00366 |
ANGPT1/Angiopoietin-1 Protein, Cynomolgus, Recombinant (His)
angiopoietin 1 |
Cynomolgus | HEK293 Cells |
ANGPT1/Angiopoietin-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the accession number is XP_005563980.1. | |||
TMPY-05294 |
ANGPTL3 Protein, Mouse, Recombinant (His)
angiopoietin-like 3,hypl |
Mouse | Baculovirus Insect Cells |
ANGPTL3 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q3UEF5. | |||
TMPY-04226 |
Influenza A H5N1 (A/goose/Guangdong/1/1996) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/goose/Guangdong/1/1996) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q9Q0U6. | |||
TMPY-04527 |
Influenza A H3N2 (A/Chiang Rai/277/2011) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Chiang Rai/277/2011) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa. | |||
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