348
40
1
49
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CEPY-0006 |
Human Cystatin SN/CST1 ELISA Pair Set
Human Cystatin SN/CST1 ELISA 抗体对 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5457 |
SN 6
SN6 |
Calcium Channel; Na+/Ca2+ Exchanger | Membrane transporter/Ion channel; Metabolism |
SN 6 (SN6) 是选择性NCX 抑制剂,可抑制 NCX1、NCX2 和 NCX3 对45Ca2+的吸收,IC50值分别为 2.9、16 和 8.6 μM。 | |||
T12941 |
SN 2
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
SN 2 是TRPML3离子通道的有效激活剂,EC50为 1.8 μM。它对登革热病毒 2 和寨卡病毒具有有效的抑制作用。 | |||
T9554 |
SN-008
|
STING | Immunology/Inflammation |
SN-008 是 SN-011 的低活性类似物,可作为阴性对照。 | |||
T22463 |
1,2-Dilauroyl-sn-glycerol
1,2-DLG,(S)-1,2-Dilaurin,1,2-二月桂酰-SN-甘油 |
Others | Others |
1,2-Dilauroyl-sn-glycerol ((S)-1,2-Dilaurin) 是饱和二酰甘油的一种,可能在第二信使信号转导中发挥调节作用。 | |||
T35606 |
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium
1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) |
||
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) 可与 DOPC 和 DOPE 一起用于脂质混合物中,作为有效的无毒和非病毒 DNA 载体。 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium 已用于单层囊泡的形成,以研究曲率对膜结构的影响,并用于支持脂质双层的形成,以研究各种支持膜小叶之间脂质重新分布的材料。 | |||
T9204 |
SN-001
|
STING | Immunology/Inflammation |
SN-001 是一种 STING 抑制剂,可抑制 STING 信号通路的激活并预防或治疗 STING 介导的疾病。 | |||
T9137 |
SN-011
[1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901 |
STING | Immunology/Inflammation |
SN-011 (GUN35901) 是选择性 STING 抑制剂,可与环状二核苷酸 (CDN) 竞争 STING 二聚体的结合口袋,从而阻断 CDN 结合和 STING 激活。它用于 STING 驱动的自身免疫和炎症性疾病的研究,抑制 STING 信号传导的 IC50值为 76 nM。 | |||
T22465 |
1,2-Distearoyl-sn-glycerol
|
Others | Others |
1,2-Distearoyl-sn-glycerol 是一种内标物,可用于分离和鉴定 1,2-diacyl-sn-glycerol (DAG) 的分子种类。 | |||
T17731L |
CL2A-SN-38 DCA 1279680-68-0(free base)
|
Others | Others |
CL2A-SN-38 DCA 1279680-68-0(free base) 是一种药物-接头偶联物,由有效的 DNA 拓扑异构酶 I 抑制剂 SN-38 和接头 CL2A 组成,用于制造抗体药物偶联物 (ADC)。CL2A-SN-38 由有效的 DNA 拓扑异构酶组成I 抑制剂 SN-38 和接头 CL2A 以制造抗体药物偶联物 (ADC)。 CL2A-SN-38 对一系列人类实体瘤类型提供显着和特异性的抗肿瘤作用。 CL2A 是一种不可切割的复杂 PEG8 和含有三唑的 PABC-肽-mc 接头。 CL2A 可通过 pH 敏感性裂解,产生旁观者效应,并通过二硫键在半胱氨酸残基处结合抗体。 | |||
T9788 |
SN32976
|
PI3K | PI3K/Akt/mTOR signaling |
SN32976 是一种泛 PI3K 抑制剂。 SN32976 有效抑制 PI3K 亚型和 mTOR,显示出对 PI3Kα 的优先活性和对 PI3Kδ 的保留。 | |||
T4949 |
1,2-Didecanoyl-sn-glycero-3-phosphocholi
1,2-Didecanoyl Phosphatidylcholine,1,2-Didecanoyl PC,L-A-癸酰磷脂酰胆碱 |
Others | Others |
1,2-Didecanoyl-sn-glycero-3-phosphocholi (1,2-Didecanoyl PC) 是一种合成的、疏水性较低的磷脂,已被发现可用于增强肽类药物和激素(如胰岛素)的吸收。 | |||
T10022 |
1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
|
Endogenous Metabolite | Metabolism |
1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine 是一种人内源性代谢产物。 | |||
TF0112 |
DPPS
12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na |
Others | Others |
DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) 是一种阴离子二酰基磷脂,是磷脂酰丝氨酸(PS)的一种形式,是一种位于细胞膜内小叶的带负电荷的磷脂。DPPS 被用来制作阳离子囊泡和脂质体。 | |||
T35482 |
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE,1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine |
||
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid. [1] It inhibits the growth of L. donovani promastigotes (GIC50 = 8 uM). [2]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model. [3] Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days. [1]1-Palmitoyl-2-hydroxy-sn-glycero-... | |||
T36004 |
1-O-Hexadecyl-sn-glycerol
1-O-Hexadecyl-sn-glycerol,(S)-(+)-Chimyl Alcohol,α-Chimyl Alcohol |
||
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury. [2].Maulik, N., Tosaki, A., Engelman, R.M., et al. Myocardial salvage by chimyl al... | |||
T12942L |
SN50 acetate (213546-53-3 free base)
|
NF-κB | NF-κB |
SN50 acetate (213546-53-3 free base) 是一种可渗透细胞的 NF-κB 易位抑制剂。 | |||
T34665 |
SN-1
SN1 |
||
SN-1 is a zinc chelator which increases steady-state expression level of A3G in the presence of Vif. | |||
T69193 | SN-28049 | ||
SN-28049 SN is a DNA intercalating drug that binds selectively to GC-rich DNA and shows curative activity against the Colon 38 adenocarcinoma in mice. SN 28049 has a complex action that may involve poisoning of topo IIalpha, suppression of topo I and inhibition of gene transcription from promoters with SP-1 sites. These actions may contribute to the promising experimental solid tumour anticancer activity of SN 28049. | |||
T1439 |
Lacidipine
SN-305,拉西地平,GX-1048,GR-43659X |
Apoptosis; Calcium Channel; Reactive Oxygen Species | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB |
Lacidipine (SN-305) 是一种L 型钙离子通道阻断剂。 | |||
T17731 |
CL2A-SN-38
|
Others | Others |
CL2A-SN-38 是一种药物-接头偶联物,由一种有效的 DNA 拓扑异构酶 I 抑制剂 SN-38 和接头 CL2A 组成,用于制造抗体药物偶联物。它对一系列人类实体瘤类型提供显着和特异性的抗肿瘤作用。 | |||
T0942 |
Quinacrine dihydrochloride
疟疾平,Mepacrine dihydrochloride,阿的平,SN-390,Quinacrine 2HCl |
Apoptosis; Mitophagy; DNA; Phospholipase; Parasite; Autophagy; Histamine Receptor | Apoptosis; Autophagy; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Quinacrine dihydrochloride (Mepacrine dihydrochloride) 是一种具有口服活性的抗疟剂,抑制 NF-κB 并激活 p53 信号转导,诱导肿瘤细胞发生凋亡,具有抗肿瘤和抗寄生虫活性。 | |||
T23373 |
SN 003
|
Others | Others |
SN 003 is a CRF1 antagonist. | |||
T39222 |
Mc-VC-PAB-SN38
Mc-VC-PAB-SN38 |
Others | Others |
Mc-VC-PAB-SN38 由可降解 (cleavable) 的 ADC linker (Mc-VC-PAB) 和 SN38 组成,属于抗体偶联活性分子的一部分,常用来合成靶向作用位点的抗体偶联活性分子 (ADC)。 | |||
T6615 |
Ondansetron
GR-C507/75,GR 38032,昂丹司琼,GR 38032F,SN 307,恩丹西酮 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Ondansetron (GR 38032) 是一种血清素 5-HT3 受体拮抗剂,主要用作止吐剂。 | |||
T1478 |
Ondansetron hydrochloride dihydrate
盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Ondansetron hydrochloride dihydrate (GR 38032) 是5- HT3受体拮抗剂,可治疗化疗后的恶心和呕吐,有抗焦虑和抗精神病作用。 | |||
T37122 |
1,2-Dilinoleoyl-sn-glycerol
|
||
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy. | |||
T37502 |
sn-Glycerol 3-phosphate lithium
|
||
sn-Glycerol 3-phosphate lithium is synthesized via the cytosolic glycerol 3-phosphate dehydrogenase pathway. This process involves the conversion of dihydroxyacetone phosphate to sn-Glycerol 3-phosphate using NADH, which is generated during glycolysis. | |||
T10832 |
CL2-SN-38
|
Others | Others |
CL2-SN-38, a part of the antibody-drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. SN-38 is an inhibitor of DNA topoisomerase I. | |||
T37623 |
1,2-Dierucoyl-sn-glycero-3-PC
|
||
1,2-Dierucoyl-sn-glycero-3-PC is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP). | |||
T19080 |
DOPE
1,2-二油酰-SN-甘油-3-磷酰乙醇胺 |
Others | Others |
DOPE (DOPE) 是一种阳离子脂质体的中性辅助脂质 (helper lipid),能够与阳离子磷脂结合,增强裸 siRNA 的转染效率。 | |||
T36451 |
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt),biotin-cap-DPPE |
||
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid. It has been used in PEGylated polyamidoamine-dendrimer-conjugated supported lipid bilayers (SLB) to isolate circulating tumor cells and tumor cell microembolis from patient-derived blood by antibody-coated microfluidics. [1] It has also been used as a component of SLBs to detect protein-ligand binding with ortho-conjugated Texas Red DHPE. [2] In addition, 1,2-dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) has been used i... | |||
T67435 |
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
|
||
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67435,CAS号为 200880-42-8。 | |||
T40972 |
1-Oleoyl-2-acetyl-sn-glycerol
|
||
1-Oleoyl-2-acetyl-sn glycerol, a synthetic, cell-permeable diacylglycerol analog, activates calcium-dependent protein kinase C (PKC) and induces superoxide production. | |||
T38356 |
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
|
||
1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation... | |||
T40757 |
1-Stearoyl-2-arachidonoyl-sn-glycerol
|
||
1-Stearoyl-2-arachidonoyl-sn-glycerol, a diacylglycerol (DAG) encompassing polyunsaturated fatty acids, possesses the ability to activate PKC. Moreover, this compound has the potential to enhance nonselective cation channel (NSCC) activity. | |||
T29298 | 1-Dodecanoyl-sn-glycerophosphoethanolamine | ||
1-Dodecanoyl-sn-glycerophosphoethanolamine is a bioactive cehmical. | |||
T37043 |
1,2-Dihexadecyl-sn-glycero-3-PC
|
||
1,2-Dihexadecyl-sn-glycero-3-PC 可用于生命科学领域的相关研究。其产品编号为 T37043,CAS号为 36314-47-3。 | |||
T6616 |
Ondansetron hydrochloride
SN 307,盐酸昂丹司琼,帕罗西汀杂质A,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Ondansetron hydrochloride (Zofran) 是5-HT3受体的拮抗剂,可用作化疗后止吐剂。 | |||
T26196 |
SN34037
SN-34037,SN 34037 |
||
SN34037 is a specific Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) inhibitor. | |||
T18538 |
MAC glucuronide phenol-linked SN-38
|
Others | Others |
MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1]. | |||
T34671 |
SNIPER(CRABP)-11
SN 11,SN11,SN-11 |
||
SNIPER(CRABP)-11 is a potent protein degrader. SNIPER(CRABP)-11 displayed degradation activity toward the mitochondrial CRABP-II protein. | |||
T19105 |
2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol
|
Others | Others |
2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride. | |||
T32418 |
KP-1212
KP1212,SN-1212,SN 1212,SN1212,KP 1212 |
||
KP-1212( SN-1212) is a nucleoside designed for the treatment of HIV by viral mutagenesis. | |||
T36453 |
1-Myristoyl-2-hydroxy-sn-glycero-3-PE
|
||
1-Myristoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. It induces transient increases in intracellular calcium in PC12 cells. Serum levels of 1-myristoyl-2-hydroxy-sn-glycero-3-PE are elevated in patients with malignant breast cancer compared to healthy controls. | |||
T38217 |
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE
|
||
1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid and adrenic acid at thesn-1 andsn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.1 1.Hancock, S.E., Friedrich, M.G., Mitchell, T.W., et al.Decreases in phospholipids containing adrenic and arachidonic acids occur in the human hippocampus over the adult lifespanLipids50(9)861-872(2015) | |||
T35489 |
1-O-Octadecyl-2-O-methyl-sn-glycerol
|
||
1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity. | |||
T10005 |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate
|
Others | Others |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate, a phosphatidic acid, is a human endogenous metabolite. | |||
T67812 |
Tenifatecan
SN2310 |
||
Tenifatecan (SN2310) 是一种高度亲脂性的7-乙基-10-羟基喜树碱(SN)制剂,具有潜在的抗肿瘤活性。 | |||
T38460 |
SN52
|
||
SN52 is a powerful, competitive, and cell-permeable inhibitor of NF-κB2. It is a variant of the SN50 peptide. SN52 effectively prevents the nuclear translocation of p52-RelB heterodimers, exhibiting a robust radiosensitization effect on prostate cancer cells. This compound holds significant potential for cancer research purposes. | |||
T37485 |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
|
||
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1703 |
SN-38
7-乙基-10-羟基喜树碱,NK012,伊立替康杂质B,SN 38 |
DNA/RNA Synthesis; Topoisomerase; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
SN-38 (NK012) 是 DNA 拓扑异构酶 I (Topo I) 抑制剂 Irinotecan 的活性代谢产物,可以抑制 DNA 和 RNA 合成 (IC50=0.077/1.3 μM)。SN-38 具有抗肿瘤活性,可以诱导细胞自噬。 | |||
T5249 |
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine
1,2-DSPE,1,2-二硬酯酰-SN-甘油-3-磷酰乙醇胺,1,2-Distearoyl-sn-glycero-3-phosphoethan |
Others; Endogenous Metabolite | Metabolism; Others |
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) 是一种磷脂酸乙醇胺 (PE) ,能够用于合成脂质体。 | |||
T8712 |
1-Palmitoyl-sn-glycero-3-phosphocholine
1-十六酰-SN-丙三醇-磷酸胆碱,1-Hexadecanoyl-sn-glycero-3-phosphocholine |
Others | Others |
1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) 是一种用于荧光探针设计的磷酸胆碱。 | |||
T5238 |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
1,2-Dipalmitoyl-sn-glycero-3-PE,L-磷脂酰乙醇胺,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE |
Others; Endogenous Metabolite | Metabolism; Others |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) 是内源性代谢产物的一种。 | |||
T8713 |
1-Oleoyl-sn-glycero-3-phosphocholine
|
Others | Others |
1-Oleoyl-sn-glycero-3-phosphocholine 是分析溶血卵磷脂的参考。 | |||
T9525 |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine
DMPC,1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOL,二肉豆蔻酰磷脂酰胆碱(DMPC) |
Others | Others |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) 是一种用于脂质体和脂质双层的合成磷脂。它可用于脂质单层和双层的研究。 | |||
T8714 |
1-Stearoyl-sn-glycero-3-phosphocholine
1-硬脂酰-SN-甘油-3-磷酰胆碱,1-stearoyl-lysophosphatidylcholine,L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY |
Others | Others |
1-Stearoyl-sn-glycero-3-phosphocholine (L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY) 是一种用于脂质代谢研究的化学物质。 | |||
T9510 |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine
DSPC,L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL,1,2-Distearoyl-sn-glycero-3-PC,二硬脂酰磷脂酰胆碱 |
Others | Others |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) 是一种脂质纳米颗粒(LNP) 系统中的脂质成分,可用于合成脂质体。 | |||
T19085 |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分,是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。 | |||
T4950 |
1,2-Dipalmitoyl-sn-glycerol
1,2-双棕榈酸甘油酯,(S)-1,2-Dipalmitin |
Endogenous Metabolite; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism |
1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) 是内源性代谢产物的一种。 | |||
T22464 |
1,2-Dimyristoyl-sn-glycerol
1,2-DMG,1,2-二肉豆蔻酸甘油酯 |
Others; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Others |
1,2-Dimyristoyl-sn-glycerol (1,2-DMG) 是饱和二酰甘油的一种,可作为激活 PKC 的弱活性第二信使。 | |||
T4439 |
sn-Glycero-3-phosphocholine
Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC |
Endogenous Metabolite; AChE | Metabolism; Neuroscience |
sn-Glycero-3-phosphocholine (Choline glycerophosphate) 是脑磷脂生物合成的前体,能够提高胆碱在神经组织中的生物利用度。它对认知功能有显著影响,同时具有良好的耐受性和安全性,因此能够用于阿尔茨海默病和痴呆症的研究。 | |||
T8011 |
1,2-dioleoyl-sn-glycero-3-phosphocholine
二油酰磷脂酰胆碱,DOPC |
Others | Others |
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 是磷脂的一种,在胶束,脂质体和其他类型的人工膜的生成中通常单独使用或与其他组分一起使用。 | |||
T10005L |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
|
Endogenous Metabolite | Metabolism |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 是一种人内源性代谢物,是一种磷酸酯。 | |||
T19343 |
sn-Glycerol 3-phosphate
Glycerol 3-phosphate,SN-甘油3-磷酸 锂盐,sn-Glycerol 3-phosphate lithium salt |
Endogenous Metabolite | Metabolism |
sn-Glycerol 3-phosphate 是一种人内源性化合物,由NADH 还原磷酸二羟基丙酮而产生。 | |||
TN7245 |
DMPS-Na
1,2-Dimyristoyl-sn-glycero-3-phosphoserine sodium salt |
Others | Others |
DMPS-Na 是一种带有毒性的解砷灵,可用于研究细胞膜。 | |||
T5243 |
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate
DMPE,1,2-十四酰基磷脂酰乙醇胺,1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine,1,2-Dimyristoyl-sn-glycero-3-PE |
Others; Endogenous Metabolite | Metabolism; Others |
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (DMPE) 是内源性代谢产物的一种。 | |||
T7773 |
DPPC
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL,二棕榈酸磷脂酰胆碱,129Y83 |
Endogenous Metabolite | Metabolism |
DPPC (129Y83) 是一种磷酸甘油酯,能够用于制备脂质体单层。DPPC-脂质体能够用作小鼠中诱导针对 GSL 抗原的免疫应答的递送载体。 | |||
T19087 |
1-Arachidoyl-sn-glycero-3-phosphocholine
|
Others | Others |
1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP). | |||
T37280 |
PE(18:1(9Z)/0:0)
|
Endogenous Metabolite | Metabolism |
PE(18:1(9Z)/0:0) 是一种天然存在的溶血磷脂,是缩醛磷脂溶血磷脂酰乙醇胺的类似物。 PE(18:1(9Z)/0:0) 以浓度依赖性方式诱导 PC12 大鼠神经元细胞中细胞内钙的瞬时增加。 PE(18:1(9Z)/0:0) 增加 IL-4 和 IL-2 的产生,但不增加 IFN-γ 的产生。 在小鼠血清中,PE(18:1(9Z)/0:0)(1 μg/动物)诱导 T 辅助细胞 2 反应。 在寒冷暴露三天后,小鼠肩胛间棕色脂肪组织中的 PE(18:1(9Z)/0:0) 水平增加。 | |||
T64571 | 1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt | ||
1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt 是一种天然产物,可用于生命科学领域的相关研究,其产品编号为 T64571。 | |||
T74236 |
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC
|
||
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC,由油酸衍生,用于脂质体合成。 | |||
T36791 |
Lysophosphatidylcholine 18:2
|
||
1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid at thesn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.1Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.2 1.Okudaira, M., Inoue, A., Shuto, A., et al.Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MSJ. Lipid Res.55(10)2178-2192(2014) 2.Gall, ... | |||
T6354 |
(+)-Usnic acid
D-Usnic Acid,松萝酸,(+)-Usniacin,(+)-地衣酸 |
Antiviral; Antibacterial; mTOR | Immunology/Inflammation; Microbiology/Virology; PI3K/Akt/mTOR signaling |
(+)-Usnic acid (D-Usnic Acid) 是地衣中的二苯并呋喃衍生物,可结合 mTOR 的 ATP 结合口袋,抑制 mTORC1/2的活性。它诱导自噬,有抗菌和抗肿瘤活性。 | |||
T8198 |
Visnagin
|
Others | Others |
Visnagin 是一种抗氧化剂呋喃香豆素衍生物。它具有预防Cerulein 诱导的急性胰腺炎的潜力。它在血管平滑肌中具有良好的血管扩张作用。它具有抗炎作用,可用于缓解疼痛的研究。 | |||
T2731 |
Usnic Acid
Usniacin,松萝酸,地衣酸 |
Antibacterial; Autophagy | Autophagy; Microbiology/Virology |
Usnic Acid (Usniacin) 是地衣次生代谢产物,具有独特的二苯并呋喃骨架。它是一种抗菌剂、抗肿瘤剂和酶抑制剂。 | |||
T5694 |
Usnic Acid sodium
2,6-二乙酰基-7,9-二羟基-8,9b-二甲基二苯并呋喃-1,3(2H,9bH)-二酮单钠盐 |
Others | Others |
Usnic Acid sodium 是一种天然产品。 | |||
T81618 |
Officinalisnin-II
|
||
Officinalisnin-II为Asparagus filicinus根中检出的自然皂苷。 | |||
TN3585 |
Canusesnol A
|
Others | Others |
Canusesnol A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3585,CAS号为 816456-90-3。 | |||
TN5565 |
Jasnervoside G
|
||
Jasnervoside G 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5565,CAS号为 1622337-40-9。 | |||
TN5736 |
Jasnervoside C
|
||
Jasnervoside C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5736,CAS号为 1622337-36-3。 | |||
T82429 |
Euphoheliosnoid A
|
||
Euphoheliosnoid A (Compound 24) 为二萜类化合物,以 2.5 μM 浓度显著提升 NK 细胞针对 H1299-luci 及 A549-luci 细胞的杀伤效率。 | |||
T83569 |
(25R)-Officinalisnin-II
|
||
(25R)-Officinalisnin-II(化合物 5)作为一种呋甾烷醇糖苷,主要分布于Asparagus curillus果实中。 | |||
T5S0483 |
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside
(-)-丁香树脂酚-4-O-beta-D-呋喃芹糖基-(1→2)-beta-D-吡喃葡萄糖苷,(-)-Syringaresnol-4-O-beta-D-apiofuranos |
Others | Others |
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) 是从Albizzia myriophylla 的树皮部分分离得到。 | |||
T0486L |
Irinotecan Hydrochloride
盐酸伊立替康,伊立替康盐酸盐,Camptothecin 11 hydrochloride,CPT-11 hydrochloride |
Topoisomerase; Autophagy | Autophagy; DNA Damage/DNA Repair |
Irinotecan Hydrochloride (CPT-11 hydrochloride) 是喜树碱半合成衍生物的盐酸盐,是一种拓扑异构酶 I 抑制剂,可研究结肠癌和直肠癌。 | |||
T38141 |
Glycerophospholipids, cephalins
Phosphatidylethanolamines (egg) |
||
Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物,在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用,可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。 | |||
T6S1559 |
Aurantio-obtusin
|
Others | Others |
Aurantio-obtusin 是从决明子中分离出的蒽醌类化合物,具有抗炎、抗凝血、抗氧化、抗高血压的活性。它能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应,具有研究过敏相关疾病的潜力。在大鼠中,它通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉,是潜在的新型血管扩张剂。 | |||
TQ0260 |
Cerulenin
|
Antibiotic; Antifungal; Fatty Acid Synthase | Metabolism; Microbiology/Virology |
Cerulenin 是广泛使用的天然脂肪酸合成酶抑制剂。它是由真菌Cephalosporium caeruleus 产生的。它抑制拓扑异构酶I 催化活性并增强 SN-38 诱导的细胞凋亡。它具有抗真菌和抗肿瘤活性。 | |||
T37884 |
1,3-Linolein-2-Olein
|
||
1,3-Dilinoleoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains linoleic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. It has been found in grape seed, pumpkin seed, soybean, sunflower, and wheat germ oils, with the highest content in grape seed oil. | |||
T35577 |
Phosphatidylserines (bovine)
|
||
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02070 |
Cystatin SN Protein, Human, Recombinant (His)
CST1,cystatin SN |
Human | HEK293 Cells |
Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. Cystatin-SN / CST1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Cy... | |||
TMPY-03968 |
Secretogranin II Protein, Human, Recombinant (His)
EM66,SgII,SN,CHGC,secretogranin II |
Human | HEK293 Cells |
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KITL / kit ligand also belongs to the family of dimeric transmembrane growth factors. The soluble form of KIT ligand is a secreted protein. Mast cells are thought to participate in a variety of immune responses, such as parasite resistance and the allergic reaction. Mast cell devel... | |||
TMPH-00556 |
1-AGPAT Protein, E. coli, Recombinant (His)
1-AGP acyltransferase,1-AGPAT,LPAAT,1-acyl-sn-glyce... |
E. coli | P. pastoris (Yeast) |
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. 1-AGPAT Protein, E. coli, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.5 kDa and the accession number is P26647. | |||
TMPY-05847 |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.07 kDa and the accession number is A0A6G5UYK1. | |||
TMPY-06025 |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Neuraminidase/NA Protein (His)
NA Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is A0A6G5UYS3. | |||
TMPY-02707 |
PAH Protein, Human, Recombinant (415 Asn/Asp, His)
phenylalanine hydroxylase,PH,PKU1,PKU |
Human | Baculovirus Insect Cells |
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding sites for phenylalanine and to constitute an "inhibitory" domain that regulates the activity of a catalytic domain in the C-terminal portion of the molecule. In humans, PAH is expressed both in the liver and the kidney, and there is some indication that it may be differentially reg... | |||
TMPY-00109 |
Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.1 kDa and the accession number is B4URE7. | |||
TMPY-04750 |
CSNK2A2 Protein, Human, Recombinant
CK2A2,CSNK2A1,casein kinase 2, alpha prime polypept... |
Human | Baculovirus Insect Cells |
CSNK2A2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.4 kDa and the accession number is P19784. | |||
TMPY-02245 |
SNAP-25 Protein, Human, Recombinant (His)
synaptosomal-associated protein, 25kDa,SEC9,SNAP,RI... |
Human | E. coli |
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp... | |||
TMPJ-00706 |
SNCG Protein, Human, Recombinant
PRSN,Gamma-Synuclein,SNCG,BCSG1,Breast Can... |
Human | E. coli |
Gamma-Synuclein (SNCG) is a member of the Synuclein protein family. Gamma-Synuclein is mostly expressed in the peripheral nervous system and retina. Gamma-Synuclein plays a role in neurofilament network integrity and may be involved in modulating axonal architecture during development and in the adult. In addition, it may also function in modulating the keratin network in skin. SNCG expression in breast tumors has been as a marker for tumor progression. SNCG is also believed to be involved in th... | |||
TMPY-03058 |
SLITL2/VASN Protein, Human, Recombinant (His)
SLITL2,vasorin |
Human | HEK293 Cells |
Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after ... | |||
TMPY-04402 |
CSNK1G1 Protein, Human, Recombinant (His & GST)
CK1γ1,casein kinase 1, gamma 1,casein kinase 1, γ1,CK1gamma1 |
Human | Baculovirus Insect Cells |
Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are serine / threonine-selective enzymes that function as regulators ofsignal transductionpathways in most eukaryotic cell types. Casein has been used as a substrate since the earliest days of research on protein phosphorylation. Casein kinase activity associated with the endopla... | |||
TMPY-04393 |
CSNK2A2 Protein, Human, Recombinant (His & GST)
casein kinase 2, alpha prime polypeptide,CK2A2,casein kinase... |
Human | Baculovirus Insect Cells |
CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69 kDa and the accession number is P19784. | |||
TMPH-02280 |
SNRNP70 Protein, Human, Recombinant (His)
|
Human | E. coli |
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. SNRNP70 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.7 kDa and the accession n... | |||
TMPH-01370 |
SNCG Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. SNCG Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.3 kDa a... | |||
TMPH-02127 |
SNX16 Protein, Human, Recombinant (His)
|
Human | E. coli |
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. | |||
TMPJ-00790 |
GSN Protein, Human, Recombinant (mFc)
ADF,Actin-depolymerizing factor,Brevin,Gelsolin,GSN... |
Human | HEK293 Cells |
Gelsolin is a calcium-activated actin filament severing and capping protein found in many cell types and as a secreted form in the plasma of vertebrates. Gelsolin is composed of six of these domains, termed G1-6. Some reaseraches show that gelsolin can act as a transcriptional cofactor in signal transduction and its own expression and function can be influenced by epigenetic changes. The difference in the expression levels of cytoplasmic and plasma gelsolin suggests that these two different form... | |||
TMPY-00151 |
Alpha SNAP Protein, Human, Recombinant (His)
N-ethylmaleimide-sensitive factor attachment protein, alpha,... |
Human | E. coli |
NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of s... | |||
TMPY-06686 |
FASN Protein, Mouse, Recombinant (His)
fatty acid synthase,FAS,A630082H08Rik |
Mouse | E. coli |
FASN Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.23 kDa and the accession number is P19096. | |||
TMPH-01054 |
CSNK1E Protein, Human, Recombinant (His)
Casein kinase I isoform epsilon,CKI-epsilon,CSNK1E,... |
Human | E. coli |
CSNK1E Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.3 kDa and the accession number is P49674. | |||
TMPY-04758 |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant
casein kinase 2, α1 polypeptide,casein kinase 2, alpha 1 pol... |
Mouse | Baculovirus Insect Cells |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 45.3 kDa and the accession number is Q60737. | |||
TMPH-01379 |
GSN Protein, Human, Recombinant (His)
|
Human | E. coli |
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. GSN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.5 kDa and the accession number is P06396. | |||
TMPJ-01048 |
VSNL1 Protein, Human, Recombinant (His)
VISL1,Visinin-Like Protein 1,Hippocalcin-Like Protein 3,HLP3... |
Human | E. coli |
Visinin-Like Protein 1 (VILIP) is a a member of the Visinin/Recoverin subfamily of neuronal calcium sensor proteins. VILIP is strongly expressed in the Granule Cells of the Cerebellum where it associates with membranes in a Calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of Adenylyl Cyclase. It has been shown that VILIP regulates the inhibition of rhodopsin phosphorylation in a Calcium-depende... | |||
TMPY-06683 |
FASN Protein, Human, Recombinant (His)
OA-519,fatty acid synthase,FAS,SDR27X1 |
Human | E. coli |
FASN Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.26 kDa and the accession number is P49327. | |||
TMPJ-00684 |
SNCA Protein, Mouse, Recombinant (His)
Snca,Non-A β component of AD amyloid,Non-A4 compone... |
Mouse | E. coli |
Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease. Manyneurodegenerative diseases has shown that alpha-synuclein accumulates in dystrophic neurites and in Lewy bodies. The function of alpha-synuclein is closely correlated with its three-dimensional structure, especially for proteins important... | |||
TMPH-02104 |
Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein. | |||
TMPH-00323 |
Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)
|
Calloselasma rhodostoma | E. coli |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom... | |||
TMPH-00320 |
Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)
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Calloselasma rhodostoma | P. pastoris (Yeast) |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo... | |||
TMPJ-00543 |
CDSN Protein, Human, Recombinant (His)
S Protein,CDSN,Corneodesmosin |
Human | HEK293 Cells |
Corneodesmosin is a protein that is encoded by the CDSN gene in humans. This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. | |||
TMPH-02430 |
SNCG Protein, Cynomolgus, Recombinant
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Cynomolgus | E. coli |
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. SNCG Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.3 kDa and the accession number is Q2P... | |||
TMPJ-00023 |
SNCA Protein, Human, Recombinant (His)
α-Synuclein,Alpha-Synuclein,PARK1,Non-A β Component of AD Am... |
Human | E. coli |
SNCA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P37840. | |||
TMPJ-00683 |
SNCA Protein, Mouse, Recombinant
NACP,α-synuclein,Non-A beta component of AD amyloid,Non-A β ... |
Mouse | E. coli |
SNCA Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is O55042. | |||
TMPH-00321 |
Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)
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Calloselasma rhodostoma | E. coli |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo... | |||
TMPY-00722 |
Contactin 3 Protein, Human, Recombinant (708 Asp/Asn, hFc)
PCS,contactin 3 (plasmacytoma associated),BIG-1,PANG |
Human | HEK293 Cells |
Contactin 3 Protein, Human, Recombinant (708 Asp/Asn, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 134.5 kDa and the accession number is Q9P232. | |||
TMPY-04441 |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST)
casein kinase 2, alpha 1 polypeptide,casein kinase 2, α1 pol... |
Mouse | Baculovirus Insect Cells |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.9 kDa and the accession number is Q60737. | |||
TMPH-00322 |
Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)
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Calloselasma rhodostoma | P. pastoris (Yeast) |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom... | |||
TMPH-01365 |
SNTG1 Protein, Human, Recombinant (His & Myc)
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Human | E. coli |
Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation. SNTG1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicte... | |||
TMPH-02113 |
SSNA1 Protein, Human, Recombinant (His)
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Human | E. coli |
N/A. SSNA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.0 kDa and the accession number is O43805. | |||
TMPY-00723 |
Contactin 3 Protein, Human, Recombinant (708 Asp/Asn, His)
BIG-1,PCS,contactin 3 (plasmacytoma associated),PANG |
Human | HEK293 Cells |
Contactin 3 Protein, Human, Recombinant (708 Asp/Asn, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 109.2 kDa and the accession number is Q9P232. | |||
TMPY-01498 |
Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B4URE7. | |||
TMPY-04372 |
CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST)
CK2 α/CSNK2A1,CKII,CSNK2A3,CK2A1,casein ki... |
Human | Baculovirus Insect Cells |
CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 71.4 kDa and the accession number is P68400-1. | |||
TMPH-00066 |
Phospholipase A2 Protein, Apis mellifera, Recombinant (His)
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Apis mellifera | E. coli |
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. | |||
TMPH-02691 |
PLA2G12A Protein, Mouse, Recombinant (His & Myc)
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Mouse | Baculovirus Insect Cells |
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine. PLA2G12A Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.6 kDa and the accession number is Q9EPR2. | |||
TMPJ-00553 |
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
PAF Acetylhydrolase,LDL-Associated Phospholipase A2,LDL-PLA(... |
Human | HEK293 Cells |
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presen... | |||
TMPJ-01054 |
PAFAHB Protein, Human, Recombinant (His)
PAFAH Subunit Beta,PAF-AH 30 kDa Subunit,Platelet-Activating... |
Human | E. coli |
Platelet-Activating Factor Acetylhydrolase IB Subunit β (PAFAHB) is a cytoplasmic hydrolase. PAFAHB is a member of the GDSL lipolytic enzyme family. It also belongs to Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. Cytosolic PAF-AH IB is formed of three subunits of 45 kDa (alpha), 30 kDa (beta) and 29 kDa (gamma), PAFAHB is a catalytic subunit. PAFAHB inactivates PAF by removing the acetyl group at the sn-2 position. | |||
TMPH-02690 |
PLA2G10 Protein, Mouse, Recombinant (His & Myc)
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Mouse | E. coli |
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li... | |||
TMPY-02162 |
Phospholipase A2 IIE/PLA2G2E Protein, Mouse, Recombinant (His)
phospholipase A2, group IIE |
Mouse | HEK293 Cells |
Group IIE secretory phospholipase A2, also known as GIIE sPLA2, sPLA2-IIE, Phosphatidylcholine 2-acylhydrolase 2E and PLA2G2E is a secreted protein that belongs to the phospholipase A2 family. Mammalian secretory phospholipase A2s (sPLA2s) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via the release of arachidonic acid from membrane phospholipids or the binding to specific membrane receptors. Phospholipases A2 / PLA2 are... | |||
TMPY-02181 |
PLA2G12B Protein, Mouse, Recombinant (His)
Fksg71,2010002E04Rik,Pla2g13,hlb218,phospholipase A2, group ... |
Mouse | HEK293 Cells |
Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein that belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strongly expressed in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via th... | |||
TMPH-01689 |
PLD6 Protein, Human, Recombinant (His)
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Human | E. coli |
Presents phospholipase and nuclease activities, depending on the different physiological conditions. Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the nuclease activity. Plays a key role in mitochondrial fusion and fission via its phospholipase activity. In its phospholipase role, it uses the mitochondrial lipid cardiolipin as substrate to generate phosphatidate (PA or 1,2-diacyl-sn-glycero-3-phosphate), a second messenger sig... |