Prostaglandin Receptor

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, , PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2), and PGH2.[1] They are named based on the prostanoid to which they preferentially bind and respond, e.g. the receptor responsive to PGI2 at lower concentrations than any other prostanoid is named the Prostacyclin receptor (IP). One exception to this rule is the receptor for thromboxane A2 (TP) which binds and responds to PGH2 and TXA2 equally well.

Cat. No.	Product Name	CAS No.	Purity
T17039	Terbogrel 特波格雷	149979-74-8	98%
T17039	Terbogrel 是一种可口服的、具有选择性 thromboxane A2 受体拮抗剂（IC50 约为 10 nM），是一种 thromboxane A2 synthase 抑制剂（IC50 约为 10 nM）。Terbogrel 是一种抗血小板化合物，可抑制血小板聚集，是预防血栓的潜在化合物。
T68155	Tebufelone 特丁非隆	112018-00-5	98%
T68155	Tebufelone 是一种体外高效的CO 抑制剂，是一种新型的非甾体抗炎药（NSAID），属于二叔丁基苯酚（DTBP）类，在各种动物模型中显示出强大的抗炎、镇痛和抗网膜炎特性。Tebufelone 能有效地抑制前列腺素（PGE2）的形成，阻止大鼠巨噬细胞（IC50 = 20 microM）和人类全血（IC50 = 2...
T24567	Octimibate 辛米贝特	89838-96-0	98%
T24567	Octimibate 是一种非前列腺素类血小板聚集抑制剂和环前列腺素激动剂。Octimibate 可用于治疗心血管疾病，可用于研究动脉粥样硬化和血栓形成。
T27630	Isbogrel 伊波格雷	89667-40-3	98%
T27630	Isbogrel是一种小分子血栓素A2合成酶（TXA2 synthase）抑制剂，可用来研究心律失常、短暂性脑缺血发作和血栓形成。
T13563	AZ-1355 化合物AZ-1355	75451-07-9	98%
T13563	AZ-1355是一种新型二苯并恶西平衍生物，具有降脂效果。
T3P2855	Chamigrenal 恰米醛	19912-84-6	98%
T3P2855	β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 3-O-乙酰基-16Α-羟基松苓新酸	168293-14-9	98%
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞，减少NO 产生和 iNOS 表达，具有消炎作用。
TN4592	Murrangatin 化合物 TN4592	37126-91-3	98%
TN4592	Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the hig...
TN5248	Voleneol 化合物 TN5248	70389-88-7	98%
TN5248	1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependent...
TN3366	Ailanthoidol 化合物 TN3366	156398-61-7	98%
TN3366	Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potentia...
T13488	2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 化合物 T13488	137089-36-2	98%
T13488	2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer. It can maintain the content of phospholipase A2 and pros...
T4484	1,7-Dihydroxy-2,3-methylenedioxyxanthone 1,7-二羟基-2,3-亚甲二氧基呫吨酮	183210-63-1	98%
T4484	1,7-Dihydroxy-2,3-methylenedioxyxanthone has antiulcerogenic, anti-oxidation, and antihyperalgesic activities, it can inhibit the carrageenan-induced hyperalgesi...
T14500	BAY-1316957 化合物 T14500	1613264-40-6	98%
T14500	BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1].
TN4465	Luvangetin 化合物 TN4465	483-92-1	98%
TN4465	Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection agains...
TN4038	Eupatolide 泽兰内酯	6750-25-0	98%
TN4038	Eupatolide 是从 Inula japonica 的花中分离出来的，具有抗炎活性。 Eupatolide 可用于研究乳腺癌细胞对 TRAIL 的耐药性。
TN3587	Capillarisin 化合物 TN3587	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T16388	Omidenepag isopropyl 化合物 T16388	1187451-19-9	98%
T16388	Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration. Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenep...
TN5033	Skullcapflavone I 化合物 TN5033	41060-16-6	98%
TN5033	Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and...
TN1485	Chicanine 襄五脂素	78919-28-5	98%
TN1485	Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.
T16011	Manumycin A 手霉素A	52665-74-4	98%
T16011	Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inh...