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Prostaglandin Receptor

Prostaglandin Receptor

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, , PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2), and PGH2.[1] They are named based on the prostanoid to which they preferentially bind and respond, e.g. the receptor responsive to PGI2 at lower concentrations than any other prostanoid is named the Prostacyclin receptor (IP). One exception to this rule is the receptor for thromboxane A2 (TP) which binds and responds to PGH2 and TXA2 equally well.
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Cat. No. Product Name CAS No. Purity Chemical Structure
T17039 Terbogrel
特波格雷
149979-74-8 98%
Terbogrel 是一种可口服的 、具有选择性 thromboxane A2 受体拮抗剂(IC50 约为 10 nM),是一种 thromboxane A2 synthase 抑制剂(IC50 约为 10 nM)。Terbogrel 是一种抗血小板化合物,可抑制血小板聚集,是预防血栓的潜在化合物。
T68155 Tebufelone
特丁非隆
112018-00-5 98%
Tebufelone 是一种体外高效的CO 抑制剂 ,是一种新型的非甾体抗炎药(NSAID),属于二叔丁基苯酚(DTBP)类,在各种动物模型中显示出强大的抗炎、镇痛和抗网膜炎特性。Tebufelone 能有效地抑制前列腺素(PGE2)的形成,阻止大鼠巨噬细胞(IC50 = 20 microM)和人类全血(IC50 = 2...
T24567 Octimibate
辛米贝特
89838-96-0 98%
Octimibate 是一种非前列腺素类血小板聚集抑制剂和环前列腺素激动剂。Octimibate 可用于治疗心血管疾病,可用于研究动脉粥样硬化和血栓形成。
T27630 Isbogrel
伊波格雷
89667-40-3 98%
Isbogrel是一种小分子血栓素A2合成酶(TXA2 synthase)抑制剂,可用来研究心律失常、短暂性脑缺血发作和血栓形成。
T13563 AZ-1355
化合物AZ-1355
75451-07-9 98%
AZ-1355是一种新型二苯并恶西平衍生物,具有降脂效果。
T3P2855 Chamigrenal
恰米醛
19912-84-6 98%
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
TN1109 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid
3-O-乙酰基-16Α-羟基松苓新酸
168293-14-9 98%
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞,减少NO 产生和 iNOS 表达,具有消炎作用。
TN4592 Murrangatin
化合物 TN4592
37126-91-3 98%
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the hig...
TN5248 Voleneol
化合物 TN5248
70389-88-7 98%
1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependent...
TN3366 Ailanthoidol
化合物 TN3366
156398-61-7 98%
Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potentia...
T13488 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
化合物 T13488
137089-36-2 98%
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer. It can maintain the content of phospholipase A2 and pros...
T4484 1,7-Dihydroxy-2,3-methylenedioxyxanthone
1,7-二羟基-2,3-亚甲二氧基呫吨酮
183210-63-1 98%
1,7-Dihydroxy-2,3-methylenedioxyxanthone has antiulcerogenic, anti-oxidation, and antihyperalgesic activities, it can inhibit the carrageenan-induced hyperalgesi...
T14500 BAY-1316957
化合物 T14500
1613264-40-6 98%
BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1].
TN4465 Luvangetin
化合物 TN4465
483-92-1 98%
Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection agains...
TN4038 Eupatolide
泽兰内酯
6750-25-0 98%
Eupatolide 是从 Inula japonica 的花中分离出来的,具有抗炎活性。 Eupatolide 可用于研究乳腺癌细胞对 TRAIL 的耐药性。
TN3587 Capillarisin
化合物 TN3587
56365-38-9 98%
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T16388 Omidenepag isopropyl
化合物 T16388
1187451-19-9 98%
Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration. Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenep...
TN5033 Skullcapflavone I
化合物 TN5033
41060-16-6 98%
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and...
TN1485 Chicanine
襄五脂素
78919-28-5 98%
Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.
T16011 Manumycin A
手霉素A
52665-74-4 98%
Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inh...
Terbogrel
T17039
Terbogrel 是一种可口服的 、具有选择性 thromboxane A2 受体拮抗剂(IC50 约为 10 nM),是一种 thromboxane A2 synthase 抑制剂(IC50 约为 10 nM)。Terbogrel 是一种抗血小板化合物,可抑制血小板聚集,是预防血栓的潜在化合物。
Tebufelone
T68155
Tebufelone 是一种体外高效的CO 抑制剂 ,是一种新型的非甾体抗炎药(NSAID),属于二叔丁基苯酚(DTBP)类,在各种动物模型中显示出强大的抗炎、镇痛和抗网膜炎特性。Tebufelone 能有效地抑制前列腺素(PGE2)的形成,阻止大鼠巨噬细胞(IC50 = 20 microM)和人类全血(IC50 = 2...
Octimibate
T24567
Octimibate 是一种非前列腺素类血小板聚集抑制剂和环前列腺素激动剂。Octimibate 可用于治疗心血管疾病,可用于研究动脉粥样硬化和血栓形成。
Isbogrel
T27630
Isbogrel是一种小分子血栓素A2合成酶(TXA2 synthase)抑制剂,可用来研究心律失常、短暂性脑缺血发作和血栓形成。
AZ-1355
T13563
AZ-1355是一种新型二苯并恶西平衍生物,具有降脂效果。
Chamigrenal
T3P2855
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid
TN1109
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞,减少NO 产生和 iNOS 表达,具有消炎作用。
Murrangatin
TN4592
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the hig...
Voleneol
TN5248
1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependent...
Ailanthoidol
TN3366
Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potentia...
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
T13488
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer. It can maintain the content of phospholipase A2 and pros...
1,7-Dihydroxy-2,3-methylenedioxyxanthone
T4484
1,7-Dihydroxy-2,3-methylenedioxyxanthone has antiulcerogenic, anti-oxidation, and antihyperalgesic activities, it can inhibit the carrageenan-induced hyperalgesi...
BAY-1316957
T14500
BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1].
Luvangetin
TN4465
Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection agains...
Eupatolide
TN4038
Eupatolide 是从 Inula japonica 的花中分离出来的,具有抗炎活性。 Eupatolide 可用于研究乳腺癌细胞对 TRAIL 的耐药性。
Capillarisin
TN3587
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
Omidenepag isopropyl
T16388
Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration. Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenep...
Skullcapflavone I
TN5033
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and...
Chicanine
TN1485
Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.
Manumycin A
T16011
Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inh...
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