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Search Results for " p40 "

4

抑制剂 & 化合物

3

天然产物

29

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TF0003	Anapoe-NID-P40
	Anapoe-NID-P40 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0003，CAS号为 2497-59-8。
TP1978	11R-VIVIT NFAT inhibitor, Cell Permeable
	NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse
T64280	ODN 2216
	ODN 2216 是一种 TLR9 (toll-like receptor 9) 配体或激动剂，能够诱导产生大量的 IFN-α 和 IFN-β。ODN 2216 可以利用 pDC (浆细胞样 DC) 诱导 IFN-α，以及利用 DC (树突状细胞) 产生IL-12 (p40)。ODN 2216 能够间接的、在 IFN-α/β 介导下刺激外周血单核细胞 (PBMC) 产生 IFN-γ。ODN 2216 可以激活 NK 细胞，诱导 IFN-γ 产生 TCR 触发的 CD4+T 细胞。
TP1978L1	11R-VIVIT TFA (592517-80-1 Free base)
	11R-VIVIT TFA (592517-80-1 Free base) 是一种 NFAT 抑制剂。 11R-VIVIT TFA 抑制 LPS 或 LPS 加 IFN-γ 诱导的骨髓源性巨噬细胞 (BMDM) 分泌 IL-12 p40、IL-12 p70、IL-23 和 TNF。 11R-VIVIT TFA 减弱 LPS 刺激的 BMDM 中 NO 的产生和 Nos2 mRNA 的表达。 11R-VIVIT TFA 改善结肠炎小鼠模型的症状。 11R-VIVIT TFA 表现出免疫抑制作用并提高小鼠移植物的存活率。 11R-VIVIT TFA 具有细胞渗透性。

化合物

Anapoe-NID-P40

Cat.No: TF0003

Cat.No: TP1978

Synonym: NFAT inhibitor, Cell Permeable

Cat.No: T64280

11R-VIVIT TFA (592517-80-1 Free base)

Cat.No: TP1978L1

Cat. No.	Product Name	Target	Signaling Pathways
TN1787	Isomucronulatol 7-O-glucoside Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷	Others	Others
	Isomucronulatol 7-O-glucoside 具有潜在的抗炎活性，在体外对 LPS 刺激产生的 IL-12 p40 表现出微弱的抑制作用。
T3859	Isomucronulatol 7,2'-Dihydroxy-3',4'-dimethoxyisoflavan,7,2'-二羟基-3',4'-二甲氧基异黄烷,异短尖剑豆酚	Others	Others
	Isomucronulatol (7,2'-Dihydroxy-3',4'-dimethoxyisoflavan) 是一种黄酮类化合物，分离自 A. membranaceus 根。它在体外对 LPS 刺激产生的 IL-12 p40 有抑制作用，具有潜在的抗炎作用。
TN4190	Hedycoronen A	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, with IC(50) ranging from 4.1±0.2 to 9.1±0.3 uM, they also show moderate inhibitory activity on

天然产物

Isomucronulatol 7-O-glucoside

Cat.No: TN1787

Synonym: Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷

Target: Others

Isomucronulatol

Cat.No: T3859

Synonym: 7,2'-Dihydroxy-3',4'-dimethoxyisoflavan,7,2'-二羟基-3',4'-二甲氧基异黄烷,异短尖剑豆酚

Target: Others

Cat.No: TN4190

Target: IL Receptor, TNF

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03198	IL-12B Protein, Mouse, Recombinant (His) Il-12p40,p40,interleukin 12B,Il12p40	Mouse	HEK293 Cells
	IL-12B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is P43432.
TMPY-03516	IL-12B Protein, Mouse, Recombinant Il-12p40,interleukin 12B,Il-12b,Il12p40,	Mouse	HEK293 Cells
	IL-12B Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.6 kDa and the accession number is P43432.
TMPY-01870	IL-9 Protein, Human, Recombinant (His) P40,interleukin 9,HP40,白细胞介素,IL-9,白介素	Human	Baculovirus Insect Cells
	IL-9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is P15248.
TMPY-01045	IL-12B Protein, Human, Recombinant (His) IL-12B,IMD28,CLMF,CLMF2,NKSF2,IL12 p40,IMD29,interl...	Human	HEK293 Cells
	IL-12B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is P29460.
TMPY-02350	IL-12 Protein, Mouse, Recombinant (His) Il-12b,p35,IL-12p35,Ll12a,Il-12a,interleukin 12A,Il12p40...	Mouse	HEK293 Cells
	IL-12 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.3 kDa and the accession number is P43431&P43432.
TMPK-01378	IL-12B Protein, Cynomolgus, Recombinant (His) CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 subunit ...	Cynomolgus	HEK293 Cells
	Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi...
TMPK-00568	IL-9 Protein, Cynomolgus, Recombinant (His) P40,HP40,IL-9,T-cell growth factor P40...	Cynomolgus	HEK293 Cells
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Cynomolgu...
TMPK-00025	IL-9 Protein, Human, Recombinant (hFc) HP40,Cytokine P40,白细胞介素,Interleukin-9,白介素,...	Human	HEK293 Cells
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Human, Re...
TMPK-00026	IL-9 Protein, Mouse, Recombinant (hFc) P40,IL-9,Interleukin-9,Cytokine P40,T-cell...	Mouse	HEK293 Cells
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Mouse, Re...
TMPY-02366	IL-12B Protein, Mouse, Recombinant (hFc) Il-12p40,interleukin 12B,Il-12b,p40,Il12	Mouse	HEK293 Cells
	IL-12B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.8 kDa and the accession number is P43432.
TMPY-05221	IL-9 Protein, Mouse, Recombinant (His) Il-9,白细胞介素,interleukin 9,白介素,P40	Mouse	Baculovirus Insect Cells
	IL-9 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is P15247.
TMPJ-00216	IL-12B Protein, Human, Recombinant Interleukin-12 subunit beta,IL-12B,CLMF p40,NKSF2,I...	Human	HEK293 Cells
	Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells develop...
TMPY-00839	IL-12B Protein, Human, Recombinant (hFc) IMD29,IL-12B,interleukin 12B,CLMF2,IL12 p40,NKSF2,C...	Human	HEK293 Cells
	IL-12B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.4 kDa and the accession number is P29460.
TMPY-02349	IL-12 Protein, Mouse, Recombinant (hFc) p40,Ll12a,IL-12p35,p35,白细胞介素,Il-12p40,Il-1...	Mouse	HEK293 Cells
	IL-12 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.5 kDa and the accession number is P43431&P43432.
TMPY-02351	IL-12 Protein, Mouse, Recombinant (His & hFc) Il-12b,Il12p40,interleukin 12A,Ll12a,Il-12p40	Mouse	HEK293 Cells
	IL-12 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 85.9 kDa and the accession number is P43431&P43432.
TMPY-04539	ERK2 Protein, Human, Recombinant (GST) ERT1,ERK,PRKM1,ERK-2,p41,p41mapk,PRKM2,ERK2,p40,p42...	Human	Baculovirus Insect Cells
	ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 67 kDa and the accession number is P28482-1.
TMPY-02651	p63 Protein, Human, Recombinant (His & GST) p40,TP53L,RHS,B(p51A),p51,KET,NBP,B(p51B),OFC8,tumo...	Human	Baculovirus Insect Cells
	Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar features in their gene structures and functions. An animal model, p63-/- mice has been useful in difining the role p63 plays in the development and maintenance of stratified epithelial tissues. This p63 encoding protein p63 has a dramatic impact on replenishment of cutaneous epith...
TMPY-00065	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) Matrix protein VP40	EBOV	E. coli
	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.4 kDa and the accession number is B8XCM9.
TMPH-03727	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His)	ZEBOV	E. coli
	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.3 kDa and the accession number is Q77DJ6.
TMPH-02382	Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO)	MARV	E. coli
	Plays an essential role virus particle assembly and budding. Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 facilitates virus budding. The interaction with the nucleocapsid and the plasma membrane may also facilitate virus budding. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. May play a role in genome replication.
TMPY-02110	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) AD1,ABPP,CTFγ,APPI,ABETA,β-amyloid 40/β-APP40,Aβ,CV...	Human	E. coli
	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1.
TMPY-00284	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 78.7 kDa and the accession number is X5H596.
TMPY-00216	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.5 kDa and the accession number is B0LPL6.
TMPY-00064	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.1 kDa and the accession number is X5H596.
TMPJ-00915	HSP40 Protein, Human, Recombinant (His) HDJ1,HSPF1,DNAJ1,Heat Shock 40 kDa Protein 1,HSP40,...	Human	E. coli
	DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperones, facilitating the folding of other cellular proteins, preventing protein aggregation, or targeting improperly folded proteins to specific degradative pathways. DNAJB1 regulates cellular processes by aiding in the folding, transport and assembly. DNAJB1 contains a J-domain whic...
TMPH-03728	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His & Myc)	ZEBOV	Baculovirus Insect Cells
	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 39.1 kDa and the accession number is Q77DJ6.
TMPY-00281	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP)	EBOV	E. coli
	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 79.1 kDa and the accession number is B0LPL6.
TMPJ-00363	IL-12RB1 Protein, Human, Recombinant (hFc) IL-12R-β1,IL-12R-BETA1,IL-12 receptor subunit beta-1,IL12RB,...	Human	HEK293 Cells
	Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL...
TMPJ-01187	Siglec-E Protein, Mouse, Recombinant (hFc) SiglecE,Siglec-E	Mouse	HEK293 Cells
	Siglecs are sialic acid specific I‑type lectins that are characterized by an extracellular domain (ECD) with an N‑terminal Ig‑like V‑set domain followed by varying numbers of Ig‑like C2‑set domains. Mouse Siglec‑E, also known as Myeloid Inhibitory Siglec (MIS), is an 80 ‑ 85 kDa member of the CD33‑related subfamily of Siglecs. Rodent and primate Siglec gene families have significantly diverged, and Siglec‑9 is the most likely human ortholog of mouse Siglec‑E. Siglec‑E is expressed as a heavily N...

重组蛋白

IL-12B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03198

Species: Mouse

Expression System: HEK293 Cells

IL-12B Protein, Mouse, Recombinant

Cat.No: TMPY-03516

Species: Mouse

Expression System: HEK293 Cells

IL-9 Protein, Human, Recombinant (His)

Cat.No: TMPY-01870

Species: Human

Expression System: Baculovirus Insect Cells

IL-12B Protein, Human, Recombinant (His)

Cat.No: TMPY-01045

Species: Human

Expression System: HEK293 Cells

IL-12 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02350

Species: Mouse

Expression System: HEK293 Cells

IL-12B Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01378

Species: Cynomolgus

Expression System: HEK293 Cells

IL-9 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00568

Species: Cynomolgus

Expression System: HEK293 Cells

IL-9 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00025

Species: Human

Expression System: HEK293 Cells

IL-9 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00026

Species: Mouse

Expression System: HEK293 Cells

IL-12B Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02366

Species: Mouse

Expression System: HEK293 Cells

IL-9 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05221

Species: Mouse

Expression System: Baculovirus Insect Cells

IL-12B Protein, Human, Recombinant

Cat.No: TMPJ-00216

Species: Human

Expression System: HEK293 Cells

IL-12B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00839

Species: Human

Expression System: HEK293 Cells

IL-12 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02349

Species: Mouse

Expression System: HEK293 Cells

IL-12 Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-02351

Species: Mouse

Expression System: HEK293 Cells

ERK2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04539

Species: Human

Expression System: Baculovirus Insect Cells

p63 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02651

Species: Human

Expression System: Baculovirus Insect Cells

Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His)

Cat.No: TMPY-00065

Species: EBOV

Expression System: E. coli

Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His)

Cat.No: TMPH-03727

Species: ZEBOV

Expression System: E. coli

Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO)

Cat.No: TMPH-02382

Species: MARV

Expression System: E. coli

Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02110

Species: Human

Expression System: E. coli

Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP)

Cat.No: TMPY-00284

Species: EBOV

Expression System: E. coli

Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His)

Cat.No: TMPY-00216

Species: EBOV

Expression System: E. coli

Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His)

Cat.No: TMPY-00064

Species: EBOV

Expression System: E. coli

HSP40 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00915

Species: Human

Expression System: E. coli

Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His & Myc)

Cat.No: TMPH-03728

Species: ZEBOV

Expression System: Baculovirus Insect Cells

Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP)

Cat.No: TMPY-00281

Species: EBOV

Expression System: E. coli

IL-12RB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00363

Species: Human

Expression System: HEK293 Cells

Siglec-E Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01187

Species: Mouse

Expression System: HEK293 Cells

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