85
5
Cat. No. | Product Name | Target | Signaling Pathways |
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TP1214L |
β-Amyloid 15-21 acetate
Beta-Amyloid (15-21) acetate |
Beta Amyloid | Neuroscience |
β-Amyloid 15-21 acetate (Beta-Amyloid(15-21) acetate) 是 Amyloid-β 肽的片段,可用于神经系统疾病的研究。该片段参与β折叠形成。 | |||
TP1229 |
β-Amyloid (1-15)
Amyloid β-Protein (1-15) |
Beta Amyloid | Neuroscience |
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) 是 β-淀粉样蛋白片段,可用于研究阿尔茨海默病。 | |||
T14284 |
β-Amyloid (25-35)
β-Amyloid peptide(25-35),Aβ25-35,BETA-淀粉样蛋白片断25-35,Amyloid beta-peptide(25-35) |
Beta Amyloid | Neuroscience |
β-Amyloid (25-35) (Aβ25-35) 是一种阿尔茨海默氏淀粉样蛋白β肽的Aβ(25-35) 片段,在培养细胞中显示出神经毒性作用。 | |||
T7562 |
β-Amyloid (31-35)
异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸,β-Amyloid 31-35(TFA),β-Amyloid 31-35 |
Beta Amyloid | Neuroscience |
β-Amyloid (31-35) (β-Amyloid 31-35) 是一种天然 Amyloid-β 肽的最短序列,具有神经毒性。 | |||
T7680 |
GSNKGAIIGLM(131602-53-4(free base))
Amyloid beta-peptide(25-35),BETA-淀粉样蛋白片断25-35 |
Beta Amyloid | Neuroscience |
GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) 是阿尔茨海默病淀粉样蛋白 β-肽的片段 Aβ(25-35)。 | |||
T35499 |
β-Amyloid (1-42), (rat/mouse) (TFA)
Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA |
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β-Amyloid (1-42), (rat/mouse) (TFA) 是由 42 个氨基酸组成的多肽片段,可用于研究阿尔茨海默症。 | |||
TP1359L |
Amyloid β Peptide (42-1)(human) acetate
Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base) |
Beta Amyloid | Neuroscience |
Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽,其在阿尔茨海默病的发病机制中起关键作用。 | |||
TP1733 |
Beta-Amyloid(1-14),mouse,rat
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Beta-Amyloid(1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. This peptide is amino acids 1 to 14 fragment of Beta-Amyloid peptide. | |||
TP1786L |
Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate(152286-31-2 free base) |
Beta Amyloid | Neuroscience |
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) 是 Amyloid-β 肽的片段,可能用于神经系统疾病的研究。Amyloid β 蛋白片段含有 α-分泌酶加工位点(Lys16-Leu17 键)。它还包含负责与小胶质细胞结合的 HHQK 结构域(残基 13-16)。 | |||
T32106 |
Human beta-amyloid protein 42 (1-7)
Vanutide |
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Human beta-amyloid protein 42 (1-7) is a bioactive chemical. | |||
TP1866L |
β-amyloid 1-11 acetate(190436-05-6 free base)
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Beta Amyloid | Neuroscience |
β-amyloid 1-11 acetate(190436-05-6 free base) 是 Amyloid-β 肽的片段,可用于神经系统疾病的研究。 | |||
T4398 |
LX2343
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Beta Amyloid; Beta-Secretase; BACE; PI3K; Autophagy | Autophagy; Neuroscience; PI3K/Akt/mTOR signaling |
LX2343 是一种非 ATP 竞争性 PI3K 抑制剂,IC50 为 15.99±3.23 μM。它是一种 BACE1 酶抑制剂,IC50 值为 11.43±0.36 μM。它在促进 Aβ 清除中刺激自噬。 | |||
T6562 |
Latrepirdine dihydrochloride
Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin |
Beta Amyloid; 5-HT Receptor; Adrenergic Receptor; GluR; Autophagy; Histamine Receptor | Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) 是一种具有口服活性和神经活性的多种药物靶点的拮抗剂,可刺激淀粉样前体蛋白分解代谢和 β-淀粉样蛋白分泌。 | |||
TP1214 |
β-Amyloid 15-21
Beta-Amyloid (15-21) |
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β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation. | |||
TP1231 |
β-Amyloid (29-40)
Amyloid beta-protein(29-40),β-Amyloid 29-40 |
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β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusion of liposomes can be induced by th | |||
TP1227 |
β-Amyloid (12-28)
β-amyloid 12-28,Amyloid β-Protein (12-28) |
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Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo. | |||
TP1645 |
β-Amyloid (1-9)
β-Amyloid 1-9 |
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This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism. | |||
TP1544 |
β-Amyloid (22-40)
β-Amyloid 22-40 |
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This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies. | |||
TP1538 |
β-Amyloid (1-20)
β-Amyloid 1-20 |
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This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein. | |||
TP1599 |
β-Amyloid (1-34)
β-Amyloid 1-34 |
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This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34. | |||
TP1633 |
β-Amyloid (18-28)
β-Amyloid 18-28 |
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Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice. These peptides have only amino acid residues VFF at position 18 to 20 in common, suggesting the amnestic effect of the triad. | |||
TP1225 |
β-Amyloid (22-35)
β-Amyloid 22-35,Amyloid β-Protein (22-35) |
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β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide. | |||
TP1303 |
β-Amyloid (1-40)
β-Amyloid 1-40 |
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Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases. | |||
TP1228 |
β-Amyloid (1-16)
Amyloid β-Protein (1-16),β-Amyloid 1-16 |
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β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is responsible for the formation of amyloid plaques in the brains of individuals affected by Alzheimer's disease (AD). | |||
TP1494 |
β-Amyloid (4-10)
β-Amyloid 4-10 |
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Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response. | |||
TP1866 |
β-Amyloid (1-11)
β-amyloid 1-11 |
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Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid of Alzheimer’s disease patients. | |||
TP1719 |
β-Amyloid (33-40)
β-Amyloid 33-40 |
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β-Amyloid (33-40) is a peptide consisting of amino acid of 33 to 40 of beta amyloid protein. | |||
TP1586 |
β-Amyloid (35-42)
β-Amyloid 35-42 |
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β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein. | |||
TP1500 |
β-Amyloid (1-17)
β-Amyloid 1-17 |
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This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies. | |||
TP1673 |
β-Amyloid (11-22)
β-Amyloid 11-22 |
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β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). AD is the most common neurodegenerat | |||
TP1226 |
β-Amyloid (1-28)
Amyloid β-Protein (1-28),β-Amyloid 1-28 |
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β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. | |||
T7644 |
DPN
Diarylpropionitrile,2,3-双(4-羟苯基)丙腈 |
Apoptosis; Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Autophagy | Apoptosis; Autophagy; Endocrinology/Hormones |
DPN (Diarylpropionitrile) 是一种非甾体雌激素受体 ERβ选择性配体,其 EC50值为 0.85 nM。DPN 在许多神经系统疾病具有神经保护作用。 | |||
TP1692 |
β-Amyloid (13-27)
β-Amyloid 13-27 |
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β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta amyloid formation. | |||
TP1480 |
β-Amyloid (12-20)
β-Amyloid 12-20 |
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β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has amnestic effects. | |||
TP1786 |
β-Amyloid (10-20)
Amyloid β-Protein 10-20 |
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Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains the HHQK domain (residues 13-16) re | |||
TP1230 |
β-Amyloid (1-42), (rat/mouse)
β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat) |
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Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease. | |||
T39285 |
Biotin-β-Amyloid (1-40)
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Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid- -(1-40) peptide. | |||
TP2171 |
β-amyloid (12-28) (TFA) (107015-83-8 free base)
Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA) |
Others | Others |
β-amyloid (12-28) TFA, a peptide fragment of β-amyloid protein (β1-42), is the major component of senile plaque cores. β-amyloid (12-28) has aggregation properties and the potential for Alzheimer’s disease research. | |||
T38149 |
β-Amyloid (1-43)(human)
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The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro. | |||
T37768 |
β-Amyloid (1-37) (human)
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β-Amyloid (1-37) (human) 与阿尔茨海默病的精神状态有潜在关联。 | |||
TP1359 |
β-Amyloid (42-1), human
Amyloid β Peptide (42-1)(human) |
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β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease. | |||
TP1441 |
β-Amyloid (1-40) (rat)
Amyloid β-peptide (1-40) rat,β淀粉样肽(1-40)(鼠) |
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Rat form of the beta-Amyloid (1-40) peptide | |||
T37368 | Amyloid-β (1-8) Peptide | ||
Amyloid-β (1-8) is a wild-type control for the mutation-containing amyloid-β (1-8, A2V) peptide . | |||
TP1729 |
β-Amyloid (10-35), amide
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β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide. It serves as the primary constituent of amyloid plaques found in Alzheimer's disease. | |||
TP1007 |
β-Amyloid (1-42), human
大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human |
Beta Amyloid | Neuroscience |
β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽,在阿尔茨海默病的发病机制中起关键作用。 | |||
T39146 |
β-Amyloid (1-40), FAM-labeled
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β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ ex = 492 nm and λ em = 518 nm). | |||
T35498 |
β-Amyloid (1-14),mouse,rat
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β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer’s disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. [1]. Chen GF, et al. Amyloid beta: stru... | |||
TP1337 |
β-Amyloid (1-42), rat TFA
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β-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease. | |||
T39302 |
β-Amyloid (1-38), mouse, rat
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β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide. Notably, it serves as the primary constituent of amyloid plaques associated with Alzheimer's disease. | |||
T37370 |
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
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Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM.... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN1736 |
Hibifolin
棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷 |
Adenosine deaminase | Metabolism |
Hibifolin 是一种黄酮醇糖苷,是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。 | |||
TN1038 |
Galgravin
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Apoptosis | Apoptosis |
Galgravin 是望春花中的一种天然产物,具有抗炎和体外细胞毒活性,能诱导白血病细胞凋亡。 | |||
T32614 |
L-Clausenamide
(-)-Clausenamide |
Microtubule Associated | Cytoskeletal Signaling |
L-Clausenamide 是从黄皮 (Clausena lansium (Lour) skeels) 的树叶中提取出来的生物碱,可用于提高认知功能。L-Clausenamide 对β-淀粉样蛋白 (Aβ) 毒性有抑制作用,通过抑制 tau 蛋白磷酸化阻止神经纤维缠结的形成。L-Clausenamide 具有神经保护活性,可用于调节 Aβ25-35 引发的刺激。L-Clausenamide 可用于研究阿尔兹海默症类的神经系统疾病。 | |||
T3914 |
Saikosaponin C
柴胡皂苷C,柴胡皂苷 C |
Beta Amyloid; Caspase | Apoptosis; Neuroscience; Proteases/Proteasome |
Saikosaponin C 是一种柴胡中的活性成分,能够抑制 Aβ1-40 和 Aβ1-42 的释放,抑制异常 tau 蛋白的磷酸化,但对 BACE1 的活性和表达无作用。它在阿尔滋海默症中主要靶作用于amyloid beta 和tau 蛋白。 | |||
T2S0843 |
Negletein
黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether |
IL Receptor; TNF; NOS; Interleukin | Apoptosis; Immunology/Inflammation |
Negletein (7-O-Methylbaicalein) 一种神经保护剂,可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性,其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。 |