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Targets Recommended: Apoptosis Raf Ras

32

抑制剂 & 化合物

7

天然产物

10

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6555 K-Ras(G12C) inhibitor 12

Apoptosis; Raf; Ras Apoptosis; GPCR/G Protein; MAPK
K-Ras(G12C) inhibitor 12是一种K-Ras(G12C)抑制剂,作用于H1792细胞,EC50为0.32 μM。
T8936 Proteinase K

proteinase K for tritirachium album,Protease K,蛋白酶 K

Others Others
Proteinase K (proteinase K for tritirachium album) 是一种非特异性丝氨酸蛋白酶,可用于蛋白消化。它在有 SDS 或尿素存在的情况下,在很大 pH 值 (4-12)、盐浓度和温度单位内均有活性。
T3528 Senicapoc

塞尼卡泊,ICA-17043

Potassium Channel Membrane transporter/Ion channel
Senicapoc (ICA-17043) 是有效的,选择性的Gardos 通道 (Ca2+激活的 K+通道;KCa3.1) 阻断剂,IC50为 11 nM。Senicapoc 阻断人红细胞的 Ca2+诱导的铷通量,IC50为 11 nM, 抑制红细胞脱水的IC50为 30 nM。
T35689 MTP 131 acetate

Others Others
MTP 131 acetate 是一种小的线粒体靶向四肽。
T75143 Mcl-1 inhibitor 12

Mcl-1 inhibitor12 (Example 10) 作为一种高效的MCL-1抑制剂 (Ki: 0.22 nM),主要应用于癌症研究领域。
T61514 Enpp-1-IN-12

Enpp-1-IN-12 (化合物 43) 是一种有效和具有口服活性的外核苷酸焦磷酸酶/磷酸二酯酶 1 (ENPP1) 抑制剂,Ki 值 41 nM。Enpp-1-IN-12 具有抗肿瘤活性。
T37255 12-methyl Myristic Acid methyl ester

12-methyl Myristic acid methyl ester is a methylated fatty acid methyl ester that has been found in vermicomposts of cattle manure, carica papaya leaves, and cuticular wax of K. africana. It is a volatile compound in lipid-lowering granulated tea. Levels of 12-methyl myristic acid methyl ester are decreased in T. cruzi treated with nifurtimox compared to non-treated controls.
T80345 Bovine tracheal antimicrobial peptide

Bovine tracheal antimicrobial peptide,一种自牛气管粘膜分泌的抗菌肽,对E.coliD31、K.pneumoniae13883、S.aureus25923、P.aeruginosa27853 以及C.albicans14053 均展现出显著的抗菌效果,其MIC值分别为12-25、12-25、25-50、25-50、6-12 μg/ml。
T79345 CDD-1733

SARS-CoV Microbiology/Virology
CDD-1733是SARS-CoV-2 Mpro的非共价非肽抑制剂,具有12 nM的Ki值。该化合物也能够抑制ΔP168、A173V及ΔP168/A173V Mpro突变体。
T36391 Spiro-Oxanthromicin A

Spiro-oxanthromicin A is a polyketide that has been found inStreptomyces.1It induces mislocalization of K-RAS in MDCK cells (IC50= 26.7 μM). 1.Salim, A.A., Xiao, X., Cho, K.J., et al.Rare Streptomyces sp. polyketides as modulators of K-Ras localisationOrg. Biomol. Chem.12(27)4872-4878(2014)
T73644 ARL67156 trisodium hydrate

ARL67156 (FPL 67156) trisodium hydrate 是一种ecto-ATPase 抑制剂。ARL67156 trisodium hydrate 是竞争性 NTPDase1 (CD39),NTPDase3 和 NPP1 抑制剂,Ki 分别为 11,18 和 12 μM。ARL67156 trisodium hydrate 可用于钙化性主动脉瓣疾病、哮喘等疾病的研究。
T36986 Colletodiol

Colletodiol is a fungal metabolite that has been found inD. grovesiiand has immunosuppressant and antiviral activities.1,2It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s = 12 and 5 μg/ml, respectively).1Colletodiol inhibits influenza A viral replication in HeLa-IAV-Luc cells.2 1.Fujimoto, H., Nagano, J., Yamaguchi, K., et al.Immunosuppressive components from an ascomycete, Diplogelasinospora grovesiChem. Pharm. Bull.46(3)423-429(1998) 2.Lai, W., Wang...
T35640 trans-carboxy Glimepiride

trans-carboxy Glimepiride is a metabolite of the sulfonylurea glimepiride .1It is formed from glimepiride in a two-step process mediated by the cytochrome P450 (CYP) isoform CYP2C9 and cytosolic enzymes. 1.Noh, K., Kim, E., Jeong, T.C., et al.Simultaneous determination of glimepiride and its metabolites in human plasma by liquid chromatography coupled to a tandem mass spectrometryArch. Pharm. Res.34(12)2073-2078(2011)
T38167 BE-24566B

BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist (IC50s = 11 and 3.9 μM for ETAand ETBreceptors, respectively).2 1.Kojiri, K., Nakajima, S., Fuse, A., et al.BE-24566B, a new antibiotic produced by Streptomyces violaceusnigerJ. Antibiot. (Tokyo)48(1...
T36521 Alaproclate (hydrochloride)

Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s = 18, 4, 8, and 12 mg/kg, respectively).1 Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons (IC50s = 1.1 and 6.9 μM, respectively) and does not inhibit GABA-evoked currents when used at concentratio...
T36539 Nocardamine

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lo...
T38014 Heronapyrrole B

Heronapyrrole B is a farnesylated 2-nitropyrrole bacterial metabolite that has been found inStreptomycesand has antibacterial activity.1,2It is active against the Gram-positive bacteriaS. aureusandB. subtilis(MICs = 1.8 and 7.5 μM, respectively) but not Gram-negativeP. aeruginosaorE. coli.1 1.Raju, R., Piggott, A.M., Diaz, L.X.B., et al.Heronapyrroles A-C: farnesylated 2-nitropyrroles from an Australian marine-derived Streptomyces spOrg. Lett.12(22)5158-5161(2010) 2.Matsuo, T., Hashimoto, S., Ni...
T37809 Alphitonin

Alphitonin is a flavonoid that has been found in L. leptolepis wood.1 It is also a metabolic intermediate that is formed during the catabolism of quercetin by the human gut bacteria E. ramulus.2,3 |1. Chen, K., Ohmura, W., Doi, S., et al. Termite feeding deterrent from Japanese larch wood. Bioresour. Technol. 95(2), 129-134 (2004).|2. Braune, A., Gütschow, M., Engst, W., et al. Degradation of quercetin and luteolin by Eubacterium ramulus. Appl. Environ. Microbiol. 67(12), 5558-55567 (2001).|3. J...
T35560 SAR502250

SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimer’s disease (AD)[1][2]. SAR502250 (0.01-1 μM; 36 h) attenuates the Aβ25-35-induced cell death in rat embryonic hippocampal neurons[2]. SAR502250 (1-100 mg/kg; a single p.o,) attenuates tau hyperphosphorylation in the cortex and spinal cord of transgenic mic...
T37831 CAY10641

Cytosolic phospholipase A2α (cPLA2α) specifically catalyzes the hydrolysis of arachidonic acid from thesn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process.1CAY10641 is an inactive alcohol derivative of a highly potent (IC50= 12 nM) cPLA2α inhibitor.2The parent compound demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in...
T35840 4-Amino-6-chloro-1,3-benzenedisulfonamide

4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3References1. Nishimori, I., Vullo, D., Minakuchi, T., et al. Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies ...
T35422 5'-pApA (sodium salt)

5'-pApA is a linearized form of cyclic di-AMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).1,2,3,4It is a metabolite of cyclic di-AMP formedviahydrolysis by various phosphodiesterases (PDEs).55'-pApA is intended for use as a negative control for cyclic di-AMP signaling. 1.Burdette, D.L., Monroe, K.M., Sotelo-Troha, K., et al.STING is a direct innate immune sensor of cyclic-di-GMPNature478(7370)515-518(2011) 2.Parvatiyar...
T36695 TAS-103

TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research. TAS-103 is a dual inhibitor of DNA topoisomerase I/II. TAS-103 (0.1-10 μM) is active on CCRF-CEM cells, with an IC50 value of 5 nM. TAS-103 (0.1 μM) significantly increases levels of topo IIα FITC immunofluorescence in individual CCRF-CEM cells[1]. TAS-103 (0.01-1 μM) is highly cytotoxic to Lewis lung carcinoma (LLC) cells, and Liposomal TAS-103 is almost as active as free TAS-103[2]. TAS-103 inhibits the viability ...
T35451 β-Defensin-2 (human) (trifluoroacetate salt)

β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius.2β-Defensin-2 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes.3It also stimulates calcium mobilization, migration, and proliferation of keratinocytes whe...
T36490 AZT triphosphate TEA

AZT triphosphate TFA (3'-Azido-3'-deoxythymidine-5'-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TFA also inhibits the DNA polymerase of HBV. AZT triphosphate TFA activates the mitochondria-mediated apoptosis pathway[1][2][3]. Treatment with 100 μM Zidovudine (AZT) for 48h disrupts the mitochondrial tubular network via accumulation of AZT triphosphate (AZT-TP) in ...
T38286 C26 Sphingomyelin (d18:1/26:0)

C26 Sphingomyelin (d18:1/26:0)

C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3C26 sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4[Matreya, LLC.] 1.Wang, J.-R., Zhang, H., Yau, L.D., et al.Improved sphi...
T38100 Betamethasone 21-phosphate (sodium salt hydrate)

Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection when administered at a dose of 8 mg/kg but does not prevent airway hyperresponsiveness after infection.2Betamethasone 21-phosphate inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered top...
T36215 17R(18S)-EpETE

17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases ...
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T36055 Nitisinone-13C6

Nitisinone-13C6

Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...
T37847 Zonisamide-13C2,15N

Zonisamide-13C2,15N

Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

化合物

K-Ras(G12C) inhibitor 12
Cat.No: T6555
Synonym:
Target: Apoptosis, Raf, Ras
Proteinase K
Cat.No: T8936
Synonym: proteinase K for tritirachium album,Protease K,蛋白酶 K
Target: Others
Senicapoc
Cat.No: T3528
Synonym: 塞尼卡泊,ICA-17043
Target: Potassium Channel
MTP 131 acetate
Cat.No: T35689
Synonym:
Target: Others
Mcl-1 inhibitor 12
Cat.No: T75143
Synonym:
Target:
Enpp-1-IN-12
Cat.No: T61514
Synonym:
Target:
12-methyl Myristic Acid methyl ester
Cat.No: T37255
Synonym:
Target:
Bovine tracheal antimicrobial peptide
Cat.No: T80345
Synonym:
Target:
CDD-1733
Cat.No: T79345
Synonym:
Target: SARS-CoV
Spiro-Oxanthromicin A
Cat.No: T36391
Synonym:
Target:
ARL67156 trisodium hydrate
Cat.No: T73644
Synonym:
Target:
Colletodiol
Cat.No: T36986
Synonym:
Target:
trans-carboxy Glimepiride
Cat.No: T35640
Synonym:
Target:
BE-24566B
Cat.No: T38167
Synonym:
Target:
Alaproclate (hydrochloride)
Cat.No: T36521
Synonym:
Target:
Nocardamine
Cat.No: T36539
Synonym:
Target:
Heronapyrrole B
Cat.No: T38014
Synonym:
Target:
Alphitonin
Cat.No: T37809
Synonym:
Target:
SAR502250
Cat.No: T35560
Synonym:
Target:
CAY10641
Cat.No: T37831
Synonym:
Target:
4-Amino-6-chloro-1,3-benzenedisulfonamide
Cat.No: T35840
Synonym:
Target:
5'-pApA (sodium salt)
Cat.No: T35422
Synonym:
Target:
TAS-103
Cat.No: T36695
Synonym:
Target:
β-Defensin-2 (human) (trifluoroacetate salt)
Cat.No: T35451
Synonym:
Target:
AZT triphosphate TEA
Cat.No: T36490
Synonym:
Target:
C26 Sphingomyelin (d18:1/26:0)
Cat.No: T38286
Synonym: C26 Sphingomyelin (d18:1/26:0)
Target:
Betamethasone 21-phosphate (sodium salt hydrate)
Cat.No: T38100
Synonym:
Target:
17R(18S)-EpETE
Cat.No: T36215
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Nitisinone-13C6
Cat.No: T36055
Synonym: Nitisinone-13C6
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
Zonisamide-13C2,15N
Cat.No: T37847
Synonym: Zonisamide-13C2,15N
Target:
Cat. No. Product Name Target Signaling Pathways
T3S1873 Talatisamine

塔拉乌头胺,塔拉萨敏

Potassium Channel Membrane transporter/Ion channel
Talatisamine 是一种乌头生物碱,对K+通道有特异性阻滞作用。它能减弱 beta- 淀粉样低聚物对培养的皮层神经元的毒性。
T80001 Majoranaquinone

Antibiotic Microbiology/Virology
Majoranaquinone对4种Staphylococcus菌株、1种Moraxella菌株和1种Enterococcus菌株显示出良好的抑菌作用。此外,Majoranaquinone在E.coli ATCC 25922菌株中表现出显著的外排泵抑制活性,并能有效抑制E.coli ATCC 25922和E.coli K-12 AG100的生物膜形成。
T37272 9(S),12(S),13(S)-TriHOME

9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...
T38069 Aquastatin A

Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K....
T35667 Napyradiomycin A1

Napyradiomycin A1

Napyradiomycin A1is a fungal metabolite originally isolated fromC. rubraand has diverse biological activities.1,2It is active againstS. aureus,M. luteus,B. anthracis,C. bovis, andM. smegmatis(MICs = 1.56-12.5 μg/ml).1Napyradiomycin A1is an estrogen receptor antagonist (IC50= 4.2 μM in rat uterine homogenates).2It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 μM...
T35741 Gliovirin

Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease...
T36954 Nemorosone

Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...

天然产物

Talatisamine
Cat.No: T3S1873
Synonym: 塔拉乌头胺,塔拉萨敏
Target: Potassium Channel
Majoranaquinone
Cat.No: T80001
Synonym:
Target: Antibiotic
9(S),12(S),13(S)-TriHOME
Cat.No: T37272
Synonym:
Target:
Aquastatin A
Cat.No: T38069
Synonym:
Target:
Napyradiomycin A1
Cat.No: T35667
Synonym: Napyradiomycin A1
Target:
Gliovirin
Cat.No: T35741
Synonym:
Target:
Nemorosone
Cat.No: T36954
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPK-00596 SECTM1 Protein, Human, Recombinant (hFc)

SECTM1,K-12

Human HEK293 Cells
SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.
TMPY-02045 SECTM1 Protein, Human, Recombinant (His)

K12,secreted and transmembrane 1

Human HEK293 Cells
Secreted and transmembrane 1 (SECTM1), also known as K12, is a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein of SECTM family. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes. The human K12 protein has been shown to be primarily expressed in spleen, prostate, testis, small intestine, and in peripheral blood leukocytes. The K12 protein is expressed on the cell surface in such sma...
TMPK-00940 C-MPL Protein, Mouse, Recombinant (aa 26-482, His)

MPL,c-Mpl,CD110,TPO-R,MPLV,K12

Mouse HEK293 Cells
C-MPL Protein, Mouse, Recombinant (aa 26-482, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.3 kDa and the accession number is Q08351-1.
TMPK-00494 C-MPL Protein, Cynomolgus, Recombinant (His)

TPO-R,MPLV,K12,CD110,MPL,c-Mpl

Cynomolgus HEK293 Cells
C-MPL Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.48 kDa and the accession number is A0A2K5UGC7.
TMPK-00877 C-MPL Protein, Human, Recombinant (aa 26-491, His)

MPL,c-Mpl,CD110,TPO-R,K12,MPLV

Human HEK293 Cells
C-MPL Protein, Human, Recombinant (aa 26-491, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.6 kDa and the accession number is P40238-1.
TMPY-04620 Neurofascin Protein, Human, Recombinant (hFc)

neurofascin,NRCAML,NF

Human HEK293 Cells
Neurofascin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-12.
TMPY-03797 Neurofascin Protein, Human, Recombinant (His)

neurofascin,NF,NRCAML

Human HEK293 Cells
Neurofascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.4 kDa and the accession number is O94856-12.
TMPY-00479 Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)

ARIA,neuregulin 1,GGF2,MSTP131,GGF,MST131,HGL,NDF,SMDF,HRG1,...

Human HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the accession number is Q02297-12.
TMPY-00031 Neuregulin-1/NRG1 Protein, Human, Recombinant (His)

HRG1,GGF2,HRG,NDF,MSTP131,HRGA,GGF,neuregulin 1,HGL,SMDF,ARI...

Human HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q02297-12.
TMPY-02642 UBE2W Protein, Human, Recombinant (His)

UBC16,UBC-16,ubiquitin-conjugating enzyme E2W (putative)

Human E. coli
Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of protein ubiquitination. The modification of protein with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2W is a member of th...

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