抑制性免疫检查点分子在维持免疫稳态中起着至关重要的作用:它们效应 T 细胞上的表达确保了效应 T 细胞反应的适当紧缩;它们在调节性 T (Treg) 细胞上的表达促进了Treg细胞的抑制功能。阻断共抑制分子已被证实可以增强宿主对各种癌症的免疫应答,在癌症治疗中表现出显著的临床效果。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00063 | CD160 Protein, Human, Recombinant (hFc)
CD160 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine... | |||
TMPJ-00107 | CTLA-4 Protein, Human, Recombinant (Flag)
CTLA-4 Protein, Human, Recombinant (Flag)
|
Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 20 KDa and the accession numb... | |||
TMPJ-00108 | CTLA-4 Protein, Human, Recombinant (GST)
CTLA-4 Protein, Human, Recombinant (GST)
|
Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (GST) is expressed in HEK293 mammalian cells with C-GST tag. The predicted molecular weight is 40-55 KDa and the accession num... | |||
TMPJ-00129 | BTLA Protein, Human, Recombinant (His)
BTLA Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induc... | |||
TMPJ-00173 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
|
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-50 ... | |||
TMPJ-00174 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
|
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-55 ... | |||
TMPJ-00175 | B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas,... | |||
TMPJ-00176 | B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellula... | |||
TMPJ-00179 | LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated
LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated
|
Human | HEK293 Cells |
LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weigh... | |||
TMPJ-00181 | PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-... | |||
TMPJ-00182 | PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 70-95 KDa... | |||
TMPJ-00183 | PD-L1 Protein, Human, Recombinant (Flag)
PD-L1 Protein, Human, Recombinant (Flag)
|
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 35-40 KDa and the accession nu... | |||
TMPJ-00187 | CD300A Protein, Human, Recombinant (hFc & His)
CD300A Protein, Human, Recombinant (hFc & His)
|
Human | HEK293 Cells |
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of... | |||
TMPJ-00189 | TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)ex... | |||
TMPJ-00195 | FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
|
Cynomolgus | HEK293 Cells |
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 36... | |||
TMPJ-00197 | FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfami... | |||
TMPJ-00198 | FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 35 KDa ... | |||
TMPJ-00203 | Galectin-9 Protein, Human, Recombinant (GST)
Galectin-9 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galect... | |||
TMPJ-00208 | CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa ... | |||
TMPJ-00209 | CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 K... |