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刺激性免疫检查点蛋白

刺激性免疫检查点蛋白

刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反,共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用,激活共刺激通路可能提高检查点抑制效果,导致持久的抗肿瘤反应。

TargetMol Recombinant Protein
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Species
Canine (9)
Cynomolgus (37)
Cynomolyus (1)
Human (138)
Mouse (64)
Rabbit (4)
Rat (27)
Rhesus (27)
Expression System
Baculovirus Insect Cells (2)
E. coli (6)
HEK293 Cells (280)
P. pastoris (Yeast) (1)
Tag
Avi (6)
C-6xHis (12)
C-6xHis-Avi (2)
C-Avi-6xHis (2)
C-His (82)
C-His-Avi (32)
C-hFc (62)
C-hFc-6xHis (4)
C-hFc-Avi (15)
C-mFc (7)
C-rFc (6)
His (7)
N-10xHis (1)
N-6xHis (6)
N-6xHis-Avi (1)
N-6xHis-Flag (2)
N-6xHis-SUMO (1)
N-8xHis (1)
N-Avi-hFc (1)
N-His (10)
N-His-Avi (2)
N-His-Flag (2)
N-hFc (13)
N-mFc (6)
N-monomeric hFc (1)
N-rFc (2)
Tag Free (7)
hFc (5)
Cat. No. Product Name / Synonyms Species Expression System
TMPJ-00064 OX40L/TNFSF4 Protein, Human, Recombinant (His)
OX40L/TNFSF4 Protein, Human, Recombinant (His)
Human HEK293 Cells
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells,...
TMPJ-00075 CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular ...
TMPJ-00099 CD28 Protein, Mouse, Recombinant (hFc & His)
CD28 Protein, Mouse, Recombinant (hFc & His)
Mouse HEK293 Cells
T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signal...
TMPJ-00102 CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
Human,Cynomolyus HEK293 Cells
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is...
TMPJ-00128 SLAMF2 Protein, Mouse, Recombinant (His)
SLAMF2 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on...
TMPJ-00130 SLAMF2 Protein, Human, Recombinant (hFc & His)
SLAMF2 Protein, Human, Recombinant (hFc & His)
Human HEK293 Cells
CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains ...
TMPJ-00138 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
Human HEK293 Cells
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 K...
TMPJ-00140 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cynomolgus HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pas...
TMPJ-00141 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the...
TMPJ-00142 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 26-35 KDa a...
TMPJ-00143 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated
Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pas...
TMPJ-00144 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pas...
TMPJ-00145 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte acti...
TMPJ-00150 CD40 Ligand Protein, Human, Recombinant (Mammalian)
CD40 Ligand Protein, Human, Recombinant (Mammalian)
Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number ...
TMPJ-00151 CD40 Ligand Protein, Human, Recombinant
CD40 Ligand Protein, Human, Recombinant
Human E. coli
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPJ-00152 CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is ...
TMPJ-00153 CD40 Ligand Protein, Human, Recombinant (His & Flag)
CD40 Ligand Protein, Human, Recombinant (His & Flag)
Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa an...
TMPJ-00219 BTN3A2 Protein, Human, Recombinant (His & Avi), Biotinylated
BTN3A2 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Butyrophilin subfamily 3 member A2, also known as BT3.2, BTF3, BTF4 and BTN3A2, is a single-pass type I membrane protein. It is a member of the butyrophilin (BTN...
TMPJ-00353 ILDR2 Protein, Human, Recombinant (His)
ILDR2 Protein, Human, Recombinant (His)
Human HEK293 Cells
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasi...
TMPJ-00421 CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)
CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)
Human HEK293 Cells
CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it...
OX40L/TNFSF4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00064
Species: Human
Expression System: HEK293 Cells
Tag: N-6xHis
CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00075
Species: Mouse
Expression System: HEK293 Cells
Tag: N-10xHis
CD28 Protein, Mouse, Recombinant (hFc & His)
Cat.No: TMPJ-00099
Species: Mouse
Expression System: HEK293 Cells
Tag: C-hFc-6xHis
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPJ-00102
Species: Human,Cynomolyus
Expression System: HEK293 Cells
Tag: C-hFc-Avi
SLAMF2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00128
Species: Mouse
Expression System: HEK293 Cells
Tag: C-6xHis
SLAMF2 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00130
Species: Human
Expression System: HEK293 Cells
Tag: C-hFc-6xHis
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00138
Species: Human
Expression System: HEK293 Cells
Tag: N-6xHis-Flag
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00140
Species: Cynomolgus
Expression System: HEK293 Cells
Tag: C-6xHis-Avi
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00141
Species: Cynomolgus
Expression System: HEK293 Cells
Tag: C-hFc
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00142
Species: Cynomolgus
Expression System: HEK293 Cells
Tag: C-6xHis
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated
Cat.No: TMPJ-00143
Species: Human
Expression System: HEK293 Cells
Tag: C-Avi-6xHis
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00144
Species: Human
Expression System: HEK293 Cells
Tag: C-hFc-6xHis
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00145
Species: Mouse
Expression System: HEK293 Cells
Tag: C-hFc
CD40 Ligand Protein, Human, Recombinant (Mammalian)
Cat.No: TMPJ-00150
Species: Human
Expression System: HEK293 Cells
Tag: Tag Free
CD40 Ligand Protein, Human, Recombinant
Cat.No: TMPJ-00151
Species: Human
Expression System: E. coli
Tag: Tag Free
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00152
Species: Human
Expression System: HEK293 Cells
Tag: N-6xHis-Avi
CD40 Ligand Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00153
Species: Human
Expression System: HEK293 Cells
Tag: N-6xHis-Flag
BTN3A2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00219
Species: Human
Expression System: HEK293 Cells
Tag: C-6xHis-Avi
ILDR2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00353
Species: Human
Expression System: HEK293 Cells
Tag: C-6xHis
CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00421
Species: Human
Expression System: HEK293 Cells
Tag: C-hFc-6xHis
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