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Search Results for " nep "

Targets Recommended: Neprilysin Norepinephrine

126

抑制剂 & 化合物

24

天然产物

21

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40044	NEP VDP-green (NEP)
	NEP, a turn-on fluorescent probe employing the intramolecular charge transfer (ICT) mechanism, facilitates the detection of vicinal dithiol-containing proteins (VDPs). Notably, NEP exhibits exceptional selectivity towards VDPs in live cells and in vivo and manifests a robust green fluorescence signal at λ ex /λ em =430/535 nm. Furthermore, NEP bears promise for the potential diagnosis and study of parkinsonism.
T10918	NEP-IN-1	Neprilysin	Metabolism
	NEP-IN-1 是中性肽链内切酶 (NEP) 的抑制剂 (IC50 = 2 nM)。
T71118	NEP-28
	NEP-28 is an AR agonist. NEP28 is a new SARM exhibiting high selectivity for androgen receptor. NEP28 showed tissue-selective effect equivalent to or higher than existing SARMs. In addition, the administration of NEP28 increased the activity of neprilysin, a known Aβ-degrading enzyme.
T15696	NEP-IN-2	Others	Others
	NEP-IN-2 is an inhibitor of neutral endopeptidase. It also is used in the research of proliferation in atherosclerosis, restenosis.
TP1989	NEP(1-40) Nogo-66 (1-40)
	Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal
T81685	NEP(1-40) TFA
	NEP(1-40) TFA 是一种Nogo-66 受体 (NgR) 的肽类拮抗剂，其作用机制为通过抑制髓蛋白所引发的损伤逆转，限制小胶质细胞形态分布的变化。
T7693	Thiorphan	Neprilysin	Metabolism
	Thiorphan 是选择性neprilysin 抑制剂 (IC50:6.9 nM) 。
TQ0106	Sacubitrilat LBQ-657	Neprilysin	Metabolism
	Sacubitrilat (LBQ-657) 是活性的脑啡肽酶 (NEP) 抑制剂。
T4574	Sacubitril AHU 377,AHU377,沙库必曲,AHU-377	Neprilysin	Metabolism
	Sacubitril (AHU-377) 是一种有效的NEP 抑制剂，IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
T71116	MPT0B098
	MPT0B098 is a potent microtubule inhibitor through binding to the colchicine-binding site of tubulin. MPT0B098 is active against the growth of various human cancer cells, including chemoresistant cells with IC50 values ranging from 70 to 150 nmol/L. MPT0B098 arrests cells in the G2Â–M phase and subsequently induces cell apoptosis. In addition, MPT0B098 effectively suppresses VEGF-induced cell migration and capillary-like tube formation of HUVECs. Distinguished from other microtubule inhibitors, ...
T4200	Sacubitril hemicalcium salt AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt	Neprilysin	Metabolism
	Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂，IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
T80418	TAT-NEP1-40	Apoptosis	Apoptosis
	TAT-NEP1-40是一种能够穿透血脑屏障的多肽。它能够保护PC12细胞不受缺氧和葡萄糖剥夺(OGD)所致的损伤，同时促进神经突的生长。此外，TAT-NEP1-40通过阻断缺血性脑损伤中的细胞凋亡，对缺血后的神经功能恢复具有积极作用。该化合物适用于中枢神经系统损伤，特别是中风后的轴突再生与功能恢复方面的研究。
T2318	Sacubitril/Valsartan Sacubitril mixture with Valsartan,沙库必曲/缬沙坦,Valsartan,Sacubitril,LCZ696	Apoptosis; RAAS; Neprilysin	Apoptosis; Endocrinology/Hormones; Metabolism
	Sacubitril/Valsartan (LCZ696)，以1:1摩尔比由Valsartan（一种ARB）和Sacubitril（AHU377）组成，为创新口服血管紧张素受体-脑啡肽酶（ARN）双重抑制剂，旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡，有助于改善糖尿病心肌病。
T80420	TAT-NEP1-40 acetate	Apoptosis	Apoptosis
	TAT-NEP1-40 acetate 是促进脑卒中后轴突再生和功能恢复的候选分子。该化合物能够抵御PC12细胞的氧和葡萄糖剥夺(OGD)损伤，并促进神经突生长。它通过抑制神经元凋亡(apoptosis)作用，保护大脑免受缺血再灌注伤害，并能有效传递至大鼠的脑内。
T80419	TAT-NEP1-40 TFA	Apoptosis	Apoptosis
	TAT-NEP1-40 TFA 是一种能够穿透血脑屏障的多肽。它能够保护 PC12 细胞抵御缺氧和葡萄糖剥夺 (OGD) 的损害，并促进神经突的生长。此外，TAT-NEP1-40 TFA 可通过减少缺血性脑损伤中的细胞凋亡，以改善神经系统功能。该化合物在中枢神经系统损伤，包括中风后轴突再生及功能恢复的研究中具有潜在应用价值。
T1176	Racecadotril Acetorphan,消旋卡多曲	Neprilysin; Proteasome	Metabolism; Proteases/Proteasome; Ubiquitination
	Racecadotril (Acetorphan) 是一种中性内肽酶 (NEP) 抑制剂，具有止泻作用。Racecadotril 及其活性代谢物 Thiorphan 抑制小鼠脑中纯化的NEP 活性，Ki 分别为 4500 和 6.1 nM。
T25615	Lanepitant LY303870,LY-303870,LY 303870	Others	Others
	Lanepitant (LY303870) 是一种非肽类神经激肽-1（NK-1）拮抗剂,具有镇痛活性，可抑制神经源性硬脑膜炎症,可用于预防偏头痛。
T4635	Ralinepag APD811	Others; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Others
	Ralinepag (APD811) 是一种可口服的非前列腺素前列环素 (IP) 受体激动剂，对人和大鼠 IP 受体以及人 DP1 受体的 EC50 分别为 8.5、530 和 850 nM。
T7041	Donepezil E2020,Donepezilo,Aricept,多奈哌齐	AChE	Neuroscience
	Donepezil (Aricept) 是一种AChE 抑制剂，对牛 AChE 和人 AChE 的IC50分别为 8.12 nM 和 11.6 nM。
T17222	Velneperit 韦利贝特,S2367	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Velneperit (S2367) 是一种有效且选择性的神经肽 Y (NPY) Y5 受体，有用于治疗肥胖症的研究潜力。
T6360	3-deazaneplanocin A HCl	Others; Histone Methyltransferase	Chromatin/Epigenetic; Others
	3-deazaneplanocin A HCl 是组蛋白甲基转移酶 (EZH2) 和 S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。
T2402	Tianeptine sodium salt Tianeptine sodium,噻奈普汀钠,噻奈普汀钠盐	5-HT Receptor	GPCR/G Protein; Neuroscience
	Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。
T8140	Tianeptine 噻萘普汀,S-1574,JNJ-39823277,Tianeptine sodium,噻奈普汀,TPI-1062	5-HT Receptor	GPCR/G Protein; Neuroscience
	Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。
T3174	Taprenepag CP-544326	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Taprenepag (CP-544326) 是一种有效的选择性前列腺素 E2 受体激动剂，EC50为 2.8 nM，可用于研究开角治疗高眼压和青光眼的试验。
T16126	Monepantel AAD1566,PPL-1	AChR	Neuroscience
	Monepantel (AAD1566) 是一种有机驱虫剂，也是来自蛔虫和食管造口的烟碱乙酰胆碱受体拮抗剂，广泛用于农牧业除虫。
T15259	Evatanepag CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂，可诱导局部骨形成，EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。
T0537	Desbenzyl Donepezil Hydrochloride	Others	Others
	Desbenzyl Donepezil Hydrochloride 是 Donepezil 的杂质。
T6478	Donepezil Hydrochloride Aricept,BNAG,E2020,Donepezil HCl,盐酸多奈哌齐	AChR; AChE	Neuroscience
	Donepezil HCl(Aricept) 是可逆的选择性AChE 抑制剂，IC50=6.7 nM，对 AChE 的选择性高于 BuChE。Donepezil Hydrochloride (Aricept) 对 Aβ42 神经毒性具有神经保护作用。
T0368	Cinepazide maleate 马来酸桂哌齐特,MD-67350,Vasodistal,Brendil	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cinepazide maleate (MD-67350) 是哌嗪衍生物，是一种钙通道阻滞剂，也是一种强效血管扩张剂，可用于脑血管疾病的研究，如缺血性中风和脑梗塞等。
T2229	Tetraethylenepentamine Pentahydrochloride	Others	Others
	Tetraethylenepentamine Pentahydrochloride 是一种高亲和力的铜和锌螯合剂。
T1280	Nepafenac AL 6515,AHR 9434,奈帕芬胺	COX	Immunology/Inflammation; Neuroscience
	Nepafenac (AHR 9434) 是一种非甾体抗炎药，可抑制COX-2，是Amfenac 的原药。
T76828	Sonepcizumab LT 1009	LPL Receptor	GPCR/G Protein
	Sonepcizumab (LT 1009) 是一种完全人源化的抗 S1P 单克隆抗体。Sonepcizumab 具有抗癌活性，可用于研究转移性肾细胞癌 (mRCC) ，可预防青光眼滤过手术后的眼部瘢痕形成。
T18924	Benzenepentacarboxylic Acid 苯五甲酸,Pentacarboxybenzene	Others	Others
	Benzenepentacarboxylic Acid (Pentacarboxybenzene) 是具有发现和清除HO 自由基作用的荧光染料。
T6604	Nepicastat hydrochloride Nepicastat HCl,内匹司他盐酸盐,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl	Hydroxylase	Metabolism
	Nepicastat hydrochloride (RS-25560-197 hydrochloride) 是一种选择性的，有效的，口服活性的多巴胺 β 羟化酶(dopamine-beta-hydroxylase)抑制剂，对牛和人多巴胺 β 羟化酶的IC50分别为IC50=8.5 nM 和IC50=9 nM。Nepicastat HCl 可以穿过血脑屏障。
T25616	Lanepitant 2HCl LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Lanepitant 2HCl 是一种非肽类神经激肽-1 受体拮抗剂，具有镇痛和抗炎活性。Lanepitant 2HCl 抑制 P 物质与神经激肽-1 受体的结合，抑制神经源性炎症和疼痛传递，可用于研究偏头痛等疼痛性神经病变类疾病。
T39477	Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Ca-DTPA trisodium salt hydrate	Others	Others
	Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) 是螯合剂和有用的解毒剂，如急性镉中毒。它是一种无毒的 CMV 复制抑制剂。
T23380	Sonepiprazole	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Sonepiprazole 是D4多巴胺受体选择性拮抗剂，与rD4多巴胺受体，hD4.2多巴胺受体，rD2多巴胺受体和组胺H1受体结合的Ki 分别为 3.6、10.1、5147 和 7430 nM。
T33642	Nepedinol
	Nepedinol is a bioactive chemical.
T71693	Nepadutant
	Nepadutant 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T71693，CAS号为 183747-35-5。
T125814	3,4-Dimethoxybenzenepropanamine
	3,4-Dimethoxybenzenepropanamine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125814，CAS号为 14773-42-3。
T6356	(R)-Nepicastat HCl RS-25560-198 HCl,盐酸内匹司他	Hydroxylase	Metabolism
	(R)-Nepicastat HCl (RS-25560-198 HCl) 是 Nepicastat HCl 的 R-对映异构体，是一种有效的选择性抑制剂，对牛和人多巴胺-β-羟化酶的 IC50 分别为 25.1 nM 和 18.3 nM，对其他 12 种酶和 13 种神经递质受体的亲和力可忽略不计.
T83676	Tianeptine Metabolite MC5 sodium
	Tianeptine metabolite MC5是一种来自非典型抗抑郁化合物tianeptine的活性代谢物，通过β-氧化形成。此代谢物在使用表达人类μ-阿片受体（MOR）而非人类δ-阿片受体（DOR；EC50s = 0.454和 >100 µM, 分别）的HEK293T细胞进行的生物发光共振能量转移(BRET)试验中，特异性诱导G蛋白激活。在野生型小鼠上，30 mg/kg剂量的Tianeptine metabolite MC5可减少强迫游泳测试中的静止时间，但在MOR敲除小鼠中则不会，表明其具有MOR依赖的抗抑郁样活性。
T6292	3-Deazaneplanocin A	Histone Methyltransferase	Chromatin/Epigenetic
	3-Deazaneplanocin A 是组蛋白甲基转移酶(EZH2)和 S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。
T73773	Metanephrine
	Metanephrine 是肾上腺素的 O-甲基化代谢物，可用于嗜铬细胞瘤的研究。
T70697	(+)-Donepezil
	(+)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.
T28885	Sunepitron HCl CP 93,393,CP93,393,CP-93393,CP93393,CP 93393,CP-93,393
	Sunepitron is a combined α2-adrenergic receptor antagonist and 5-HT1A receptor agonist.
T125360	2-Hydroxy-4-methoxybenzenepropanoic acid
	2-Hydroxy-4-methoxybenzenepropanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125360，CAS号为 21144-17-2。
T31704	Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate
	Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate is a bioactive chemical.
T0368L	Cinepazide Brendil,MD67350,Vasodistal,Cinepazide free base,MD-67350,MD 67350,NSC 291562
	Cinepazide is a vasodilator used for the treatment of cardiovascular, cerebrovascular, and peripheral vascular diseases. Cinepazide acts as a potentiator of adenosine A2 receptors.
T70714	(-)-Donepezil
	(-)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.

化合物

Cat.No: T40044

Synonym: VDP-green (NEP)

Cat.No: T10918

Target: Neprilysin

Cat.No: T71118

Cat.No: T15696

Target: Others

Cat.No: TP1989

Synonym: Nogo-66 (1-40)

NEP(1-40) TFA

Cat.No: T81685

Cat.No: T7693

Target: Neprilysin

Cat.No: TQ0106

Synonym: LBQ-657

Target: Neprilysin

Cat.No: T4574

Synonym: AHU 377,AHU377,沙库必曲,AHU-377

Target: Neprilysin

Cat.No: T71116

Sacubitril hemicalcium salt

Cat.No: T4200

Synonym: AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt

Target: Neprilysin

Cat.No: T80418

Target: Apoptosis

Sacubitril/Valsartan

Cat.No: T2318

Synonym: Sacubitril mixture with Valsartan,沙库必曲/缬沙坦,Valsartan,Sacubitril,LCZ696

Target: Apoptosis, RAAS, Neprilysin

TAT-NEP1-40 acetate

Cat.No: T80420

Target: Apoptosis

TAT-NEP1-40 TFA

Cat.No: T80419

Target: Apoptosis

Cat.No: T1176

Synonym: Acetorphan,消旋卡多曲

Target: Neprilysin, Proteasome

Cat.No: T25615

Synonym: LY303870,LY-303870,LY 303870

Target: Others

Cat.No: T4635

Synonym: APD811

Target: Others, Prostaglandin Receptor

Cat.No: T7041

Synonym: E2020,Donepezilo,Aricept,多奈哌齐

Target: AChE

Cat.No: T17222

Synonym: 韦利贝特,S2367

Target: Neuropeptide Y Receptor

3-deazaneplanocin A HCl

Cat.No: T6360

Target: Others, Histone Methyltransferase

Tianeptine sodium salt

Cat.No: T2402

Synonym: Tianeptine sodium,噻奈普汀钠,噻奈普汀钠盐

Target: 5-HT Receptor

Cat.No: T8140

Synonym: 噻萘普汀,S-1574,JNJ-39823277,Tianeptine sodium,噻奈普汀,TPI-1062

Target: 5-HT Receptor

Cat.No: T3174

Synonym: CP-544326

Target: Prostaglandin Receptor

Cat.No: T16126

Synonym: AAD1566,PPL-1

Target: AChR

Cat.No: T15259

Synonym: CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸

Target: Prostaglandin Receptor

Desbenzyl Donepezil Hydrochloride

Cat.No: T0537

Target: Others

Donepezil Hydrochloride

Cat.No: T6478

Synonym: Aricept,BNAG,E2020,Donepezil HCl,盐酸多奈哌齐

Target: AChR, AChE

Cinepazide maleate

Cat.No: T0368

Synonym: 马来酸桂哌齐特,MD-67350,Vasodistal,Brendil

Target: Calcium Channel

Tetraethylenepentamine Pentahydrochloride

Cat.No: T2229

Target: Others

Cat.No: T1280

Synonym: AL 6515,AHR 9434,奈帕芬胺

Target: COX

Cat.No: T76828

Synonym: LT 1009

Target: LPL Receptor

Benzenepentacarboxylic Acid

Cat.No: T18924

Synonym: 苯五甲酸,Pentacarboxybenzene

Target: Others

Nepicastat hydrochloride

Cat.No: T6604

Synonym: Nepicastat HCl,内匹司他盐酸盐,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl

Target: Hydroxylase

Lanepitant 2HCl

Cat.No: T25616

Synonym: LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride

Target: Neurokinin receptor

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate

Cat.No: T39477

Synonym: Ca-DTPA trisodium salt hydrate

Target: Others

Cat.No: T23380

Target: Dopamine Receptor

Cat.No: T33642

Cat.No: T71693

3,4-Dimethoxybenzenepropanamine

Cat.No: T125814

(R)-Nepicastat HCl

Cat.No: T6356

Synonym: RS-25560-198 HCl,盐酸内匹司他

Target: Hydroxylase

Tianeptine Metabolite MC5 sodium

Cat.No: T83676

3-Deazaneplanocin A

Cat.No: T6292

Target: Histone Methyltransferase

Cat.No: T73773

Cat.No: T70697

Cat.No: T28885

Synonym: CP 93,393,CP93,393,CP-93393,CP93393,CP 93393,CP-93,393

2-Hydroxy-4-methoxybenzenepropanoic acid

Cat.No: T125360

Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate

Cat.No: T31704

Cat.No: T0368L

Synonym: Brendil,MD67350,Vasodistal,Cinepazide free base,MD-67350,MD 67350,NSC 291562

Cat.No: T70714

Cat. No.	Product Name	Target	Signaling Pathways
T6627	Phosphoramidon Disodium Phosphoramidon Disodium Salt,磷酰胺二钠	RAAS; Neprilysin; Others	Endocrinology/Hormones; Metabolism; Others
	Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ，中性肽内切酶 (NEP) 和血管紧张素转换酶 (ACE) 的IC50分别为 3.5 ，0.034 和 78 μM。
T8101	Nepsilon-Acetyl-L-lysine	Others; Endogenous Metabolite	Metabolism; Others
	Nepsilon-Acetyl-L-lysine 是一种氨基酸赖氨酸衍生物。
T4945	Normetanephrine hydrochloride DL-Normetanephrine hydrochloride,DL-去甲变肾上腺素盐酸盐	Endogenous Metabolite	Metabolism
	Normetanephrine hydrochloride (DL-Normetanephrine hydrochloride) 是肾上腺素的代谢物。它与肾上腺素一起存在于尿液和某些组织中。
T1287	Synephrine 辛弗林,Oxedrine	Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Synephrine (Oxedrine) 是来自 Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂，是一种生物碱。它也是一种拟交感神经化合物，能够用于减肥。
TN2326	(Z)-Butylidenephthalide (Z)-3-Butylidenephthalide	Glucosidase	Metabolism
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) 具有抗肿瘤和降血糖作用，能有效抑制胶质瘤的肿瘤生长，抑制 R-葡萄糖苷酶活性。
T7044	Norepinephrine 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol	MMP; Endogenous Metabolite; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Neuroscience; Proteases/Proteasome
	Norepinephrine (Levophed) 是β1选择性的肾上腺素能受体激动剂，EC50值为 5.37 μM。它可上调鼻咽癌肿瘤细胞中血管内皮生长因子、基质金属蛋白酶MMP-2和MMP-9的表达。
T2S1086	Nepitrin 假荆芥属苷,Nepetin-7-glucoside	Antioxidant	oxidation-reduction
	Nepitrin (Nepetin-7-glucoside) 分离自Scrophularia striata 中，具有强大的抗炎、抗关节炎作用。
T13655	DL-Norepinephrine hydrochloride 去甲肾上腺素盐酸盐,Lys,DL-lysine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	DL-Norepinephrine hydrochloride (DL-lysine) 是一种靶向α1 adrenoceptor 和β1 adrenoceptor 的神经递质，可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。
T75675	Nepasaikosaponin K	Antiviral	Immunology/Inflammation
	Nepasaikosaponin K 是一种从柴胡根中分离出来小分子化合物，具有抗流感和抗病毒活性，可用于研究病毒感染。
TN1100	Nepodin	transporter; COX; AMPK; Parasite	Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Nepodin 是从Rumex crispus 中分离的一种醌氧化还原酶抑制剂，具有抗糖尿病和抗疟疾的作用。。它通过激活 AMPK 刺激 GLUT4 向质膜的转运。
TN1154	Nepetin 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素	Calcium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮，具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
T3S2072	3-Butylidenephthalide Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯	Parasite; Glucosidase	Metabolism; Microbiology/Virology
	3-Butylidenephthalide (Butylidene phthalide) 是从 Ligusticum chuanxiongHort 鉴定出的一种邻苯二甲酸酐衍生物，有杀虫活性。
T1064	Norepinephrine bitartrate monohydrate 酒石酸去甲肾上腺素,Levophed,Noradrenaline bitartrate monohydrate,降肾上腺素	Endogenous Metabolite; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Neuroscience
	Norepinephrine bitartrate monohydrate (Levophed) 是一种β1-选择性的肾上腺素能受体激动剂，EC50为 5.37 μM。
T6688	Synephrine hydrochloride 辛弗林盐酸盐,Oxedrine hydrochloride,Synephrine HCl	Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Synephrine hydrochloride (Oxedrine hydrochloride) 是一种来自Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂的生物碱，也是一种拟交感神经化合物，能够用于减肥。
T21066	Norepinephrine bitartrate salt	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Norepinephrine bitartrate salt 是一种肾上腺素能神经递质。
T8265	p-Synephrine	Others	Others
	p-Synephrine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T8265，CAS号为 614-35-7。
T75425	Synephrine hemitartrate
	Synephrine (Oxedrine) hemitartrate，一种生物碱，是一种来自Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂。Synephrine hemitartrate 是一种拟交感神经化合物，可用于减肥。
TN4648	Nepetoidin B	IL Receptor; p38 MAPK; TNF; NOS; NF-κB; COX; Antibacterial; JNK; Antifection; Antifungal	Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience; NF-κB
	Nepetoidin B 具有抗真菌、抗细菌和抗炎作用，它可以抑制 LPS 刺激的 NO 生成，可能是通过调节 RAW 264.7 细胞中由 MKP-5/NF-ÎºB 通路介导的 iNOS 。
T83463	11(α)-Hydroxynepasaikosaponin k
	11(α)-Hydroxynepasaikosaponin k（HOSSc）是B. scorzonerifolium Willd中的一种柴胡皂苷。
T72250	4aα,7α,7aα-Nepetalactone
	4aα,7α,7aα-Nepetalactone 具有抗菌 (antibacterial) 活性，抑制Escherichia coli，Pseudomonas aeruginosa，Staphylococcus aureus，Salmonella typhi 和Enterococcus faecalis。
T60245	Norepinephrine hydrochloride
	Norepinephrine hydrochloride (Levarterenol hydrochloride) 是一种β1选择性的肾上腺素受体激动剂，EC50值为 5.37 μM。
TN1988	Nephthenol	Others	Others
	Nephthenol shows antiproliferative activity against the cell lines HUVEC and K-562 and for cytotoxicity against the cell line HeLa.
T81235	S-(-)-N-trans-Feruloyl normetanephrine
	S-(-)-N-trans-Feruloyl normetanephrine为天然产物，呈现弱抗乙酰胆碱酯酶活性，可从Bassia indica Wight地上部分提取。
T20538	Methylenephenanthrene
	Methylenephenanthrene is a biochemical substance.

天然产物

Phosphoramidon Disodium

Cat.No: T6627

Synonym: Phosphoramidon Disodium Salt,磷酰胺二钠

Target: RAAS, Neprilysin, Others

Nepsilon-Acetyl-L-lysine

Cat.No: T8101

Target: Others, Endogenous Metabolite

Normetanephrine hydrochloride

Cat.No: T4945

Synonym: DL-Normetanephrine hydrochloride,DL-去甲变肾上腺素盐酸盐

Target: Endogenous Metabolite

Cat.No: T1287

Synonym: 辛弗林,Oxedrine

Target: Endogenous Metabolite, Adrenergic Receptor

(Z)-Butylidenephthalide

Cat.No: TN2326

Synonym: (Z)-3-Butylidenephthalide

Target: Glucosidase

Cat.No: T7044

Synonym: 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol

Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy

Cat.No: T2S1086

Synonym: 假荆芥属苷,Nepetin-7-glucoside

Target: Antioxidant

DL-Norepinephrine hydrochloride

Cat.No: T13655

Synonym: 去甲肾上腺素盐酸盐,Lys,DL-lysine

Target: Adrenergic Receptor

Nepasaikosaponin K

Cat.No: T75675

Target: Antiviral

Cat.No: TN1100

Target: transporter, COX, AMPK, Parasite

Cat.No: TN1154

Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

Target: Calcium Channel, Histamine Receptor

3-Butylidenephthalide

Cat.No: T3S2072

Synonym: Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯

Target: Parasite, Glucosidase

Norepinephrine bitartrate monohydrate

Cat.No: T1064

Synonym: 酒石酸去甲肾上腺素,Levophed,Noradrenaline bitartrate monohydrate,降肾上腺素

Target: Endogenous Metabolite, Adrenergic Receptor, Autophagy

Synephrine hydrochloride

Cat.No: T6688

Synonym: 辛弗林盐酸盐,Oxedrine hydrochloride,Synephrine HCl

Target: Endogenous Metabolite, Adrenergic Receptor

Norepinephrine bitartrate salt

Cat.No: T21066

Target: Adrenergic Receptor

Cat.No: T8265

Target: Others

Synephrine hemitartrate

Cat.No: T75425

Cat.No: TN4648

Target: IL Receptor, p38 MAPK, TNF, NOS, NF-κB, COX, Antibacterial, JNK, Antifection, Antifungal

11(α)-Hydroxynepasaikosaponin k

Cat.No: T83463

4aα,7α,7aα-Nepetalactone

Cat.No: T72250

Norepinephrine hydrochloride

Cat.No: T60245

Cat.No: TN1988

Target: Others

S-(-)-N-trans-Feruloyl normetanephrine

Cat.No: T81235

Methylenephenanthrene

Cat.No: T20538

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01289	DDR1 Protein, Human, Recombinant (His) RTK6,DDR,TRKE,PTK3,NTRK4,NEP,PTK3A,MCK10,EDDR1,HGK2...	Human	HEK293 Cells
	DDR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is A0A024RCQ1.
TMPY-00760	CD10 Protein, Human, Recombinant membrane metallo-endopeptidase,CALLA,CD10,NEP,SFE	Human	HEK293 Cells
	CD10 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 80 kDa and the accession number is P08473.
TMPY-00759	CD10 Protein, Human, Recombinant (hFc) NEP,SFE,membrane metallo-endopeptidase,CD10,CALLA	Human	HEK293 Cells
	CD10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 106 kDa and the accession number is P08473.
TMPY-02315	CD10 Protein, Human, Recombinant (His) membrane metallo-endopeptidase,SFE,CALLA,NEP,CD10	Human	HEK293 Cells
	CD10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.2 kDa and the accession number is P08473.
TMPY-01093	CD10 Protein, Mouse, Recombinant (His) CALLA,SFE,CD10,C85356,6030454K05Rik,NEP,membrane me...	Mouse	HEK293 Cells
	CD10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.2 kDa and the accession number is Q61391.
TMPY-02506	DDR1 Protein, Mouse, Recombinant (hFc) AI323681,CD167a,Nep,Cak,PTK3A,6030432F18,discoidin ...	Mouse	HEK293 Cells
	DDR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71 kDa and the accession number is Q03146-1.
TMPY-02310	DDR1 Protein, Mouse, Recombinant (His) CD167a,discoidin domain receptor tyrosine kinase 1,AI323681,...	Mouse	HEK293 Cells
	DDR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa and the accession number is Q03146-1.
TMPY-04442	DDR1 Protein, Mouse, Recombinant (His & GST) 6030432F18,Nep,Cak,AI323681,CD167a,discoidin domain...	Mouse	Baculovirus Insect Cells
	DDR1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.8kDa and the accession number is Q03146-2.
TMPY-04382	DDR1 Protein, Human, Recombinant (aa 444-913, His & GST) discoidin domain receptor tyrosine kinase 1,NEP,TRK...	Human	Baculovirus Insect Cells
	DDR1 Protein, Human, Recombinant (aa 444-913, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 80 kDa and the accession number is Q08345-1.
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His) EDDR1,MCK-10,Epithelial discoidin domain-containing receptor...	Human	HEK293 Cells
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell...
TMPH-01751	Nephrin/NPHS1 Protein, Human, Recombinant (His)	Human	E. coli
	Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Nephrin/NPHS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.1 kDa and the accession number is O60500.
TMPY-06747	Nephrin Protein, Human, Recombinant (His) NPHN,nephrosis 1, congenital, Finnish type (nep...	Human	HEK293 Cells
	Nephrin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 113.07 kDa and the accession number is O60500.
TMPH-00432	Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) Diphtheria toxin,DT,NAD(+)--diphthamide ADP-ribosyltransfera...	Corynephage omega	E. coli
	Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) is expressed in E. coli.
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) NS1 Protein	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPH-02352	Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His)	H3N2	E. coli
	Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02353	Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO)	H1N1	E. coli
	Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02351	Influenza A H3N2 (strain A/Beijing/353/1989) Nucleoprotein/NP Protein (His & SUMO)	H3N2	E. coli
	Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02354	Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO)	H1N1	E. coli
	Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02355	Influenza A H3N2 (strain A/Port Chalmers/1/1973) Nucleoprotein/NP Protein (His & SUMO)	H3N2	E. coli
	Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02350	Influenza A H3N2 (strain A/Shanghai/16/1989) Nucleoprotein/NP Protein (His)	H3N2	E. coli
	Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02346	Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc)	H1N1	E. coli
	Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. For...

重组蛋白

DDR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01289

Species: Human

Expression System: HEK293 Cells

CD10 Protein, Human, Recombinant

Cat.No: TMPY-00760

Species: Human

Expression System: HEK293 Cells

CD10 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00759

Species: Human

Expression System: HEK293 Cells

CD10 Protein, Human, Recombinant (His)

Cat.No: TMPY-02315

Species: Human

Expression System: HEK293 Cells

CD10 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01093

Species: Mouse

Expression System: HEK293 Cells

DDR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02506

Species: Mouse

Expression System: HEK293 Cells

DDR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02310

Species: Mouse

Expression System: HEK293 Cells

DDR1 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04442

Species: Mouse

Expression System: Baculovirus Insect Cells

DDR1 Protein, Human, Recombinant (aa 444-913, His & GST)

Cat.No: TMPY-04382

Species: Human

Expression System: Baculovirus Insect Cells

DDR1 Protein, Human, Recombinant (aa 21-417, His)

Cat.No: TMPH-01297

Species: Human

Expression System: HEK293 Cells

Nephrin/NPHS1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01751

Species: Human

Expression System: E. coli

Nephrin Protein, Human, Recombinant (His)

Cat.No: TMPY-06747

Species: Human

Expression System: HEK293 Cells

Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc)

Cat.No: TMPH-00432

Species: Corynephage omega

Expression System: E. coli

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

Cat.No: TMPY-02219

Species: H1N1

Expression System: E. coli

Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His)

Cat.No: TMPH-02352

Species: H3N2

Expression System: E. coli

Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO)

Cat.No: TMPH-02353

Species: H1N1

Expression System: E. coli

Influenza A H3N2 (strain A/Beijing/353/1989) Nucleoprotein/NP Protein (His & SUMO)

Cat.No: TMPH-02351

Species: H3N2

Expression System: E. coli

Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO)

Cat.No: TMPH-02354

Species: H1N1

Expression System: E. coli

Influenza A H3N2 (strain A/Port Chalmers/1/1973) Nucleoprotein/NP Protein (His & SUMO)

Cat.No: TMPH-02355

Species: H3N2

Expression System: E. coli

Influenza A H3N2 (strain A/Shanghai/16/1989) Nucleoprotein/NP Protein (His)

Cat.No: TMPH-02350

Species: H3N2

Expression System: E. coli

Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc)

Cat.No: TMPH-02346

Species: H1N1

Expression System: E. coli

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