B细胞,也称为B淋巴细胞,是淋巴细胞亚型的一种白细胞。它们在适应性免疫系统的体液免疫成分中起作用。在哺乳动物中,B细胞在骨髓中成熟。B 细胞活化发生在次级淋巴器官 (SLO) 中,例如脾脏和淋巴结。B细胞在骨髓中成熟后,它们通过血液迁移到SLO,SLO通过循环淋巴液获得持续的抗原供应。在 SLO 中,当 B 细胞通过其 BCR 与抗原结合时,B 细胞激活开始。
未成熟的 B 细胞可表达 CD19、CD20、CD34、CD38 和 CD45R。大多数成熟 B 细胞表达IgM、CD19、CD20 和 CD22。活化的 B 细胞会表达 CD30。血浆 B 细胞不能表达 CD19,但可表达 CD78。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00066 | BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
|
Human | Human Cells |
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consis... | |||
TMPJ-00099 | CD28 Protein, Mouse, Recombinant (hFc & His)
CD28 Protein, Mouse, Recombinant (hFc & His)
|
Mouse | Human Cells |
T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signal... | |||
TMPJ-00102 | CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
|
Human,Cynomolyus | Human Cells |
T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. It belon... | |||
TMPJ-00112 | CD79B Protein, Human, Recombinant (His & Avi), Biotinylated
CD79B Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for ini... | |||
TMPJ-00118 | CD79B Protein, Rhesus macaque, Recombinant (hFc)
CD79B Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus Macaque | Human Cells |
CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for ini... | |||
TMPJ-00159 | EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated
EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | Human Cells |
Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein p... | |||
TMPJ-00160 | EMMPRIN/CD147 Protein, Human, Recombinant (His)
EMMPRIN/CD147 Protein, Human, Recombinant (His)
|
Human | Human Cells |
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain an... | |||
TMPJ-00177 | BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
|
Human | Human Cells |
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytoki... | |||
TMPJ-00178 | BAFF/TNFSF13B Protein, Human, Recombinant (His)
BAFF/TNFSF13B Protein, Human, Recombinant (His)
|
Human | Human Cells |
TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocyte... | |||
TMPJ-00184 | CD20 Protein, Human, Recombinant (Flag)
CD20 Protein, Human, Recombinant (Flag)
|
Human | Human Cells |
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ... | |||
TMPJ-00185 | CD20 Protein, Human, Recombinant (His & Flag)
CD20 Protein, Human, Recombinant (His & Flag)
|
Human | Human Cells |
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ... | |||
TMPJ-00215 | Fas/CD95 Protein, Mouse, Recombinant (hFc)
Fas/CD95 Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas ... | |||
TMPJ-00228 | SLAMF5 Protein, Human, Recombinant (His & Avi), Biotinylated
SLAMF5 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of im... | |||
TMPJ-00229 | SLAMF5 Protein, Human, Recombinant (His)
SLAMF5 Protein, Human, Recombinant (His)
|
Human | Human Cells |
SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of im... | |||
TMPJ-00284 | IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)
IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte diff... | |||
TMPJ-00285 | IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His)
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His)
|
Human | Human Cells |
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte diff... | |||
TMPJ-00329 | CD19 Protein, Rhesus macaque, Recombinant (hFc)
CD19 Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus macaque | Human Cells |
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B c... | |||
TMPJ-00353 | ILDR2 Protein, Human, Recombinant (His)
ILDR2 Protein, Human, Recombinant (His)
|
Human | Human Cells |
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasi... | |||
TMPJ-00392 | Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ... | |||
TMPJ-00393 | Siglec-2/CD22 Protein, Human, Recombinant (hFc)
Siglec-2/CD22 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ... |