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Search Results for " bca "

Targets Recommended: Others

12

抑制剂 & 化合物

2

天然产物

1

TargetMol 试剂盒

20

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
C0050	BCA Protein Quantification Kit BCA蛋白浓度测定试剂盒	Solution in bottle

TargetMol 试剂盒

BCA蛋白浓度测定试剂盒

Cat.No: C0050

Cat. No.	Product Name	Target	Signaling Pathways
T14514	BCA Disodium bicinchoninate	Others	Others
	BCA is 2,2-Biquinoline-4,4-dicarboxylic acid disodium salt.
T6916	OICR-9429 OICR 9429	Histone Methyltransferase; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	OICR-9429 是一个新颖的相互作用的小分子Wdr5-MLL 拮抗剂，IC50是 5 uM，在体外抑制急性髓性白血病细胞。
T22043	BCATc Inhibitor 2	Others	Others
	BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂，可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM)，hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1，存在于细胞质基质中的亚型。
T5198	Bobcat339 盐酸Bobcat339,Bobcat339 hydrochloride	DNA Methyltransferase	Chromatin/Epigenetic
	Bobcat339 是一种基于胞嘧啶的选择性TET 酶抑制剂，抑制TET1和TET2的IC50值分别为 33 和 73 μM。它可作为靶向 DNA 甲基化和基因转录新疗法的起点，用于表观遗传学领域研究。
T21915	TBCA Casein Kinase II Inhibitor III, TBCA	Casein Kinase	Metabolism; Stem Cells
	TBCA (Casein Kinase II Inhibitor III, TBCA) 是高选择性的酪蛋白激酶II CK2 抑制剂，IC50 为 110 nM，Ki 为 77 nM。TBCA 对 CK1、DYRK1A 和其它 27 个激酶表现出选择性。
T77522	BCAT-IN-4	Others	Others
	BCAT-IN-4 是一种具有有效性的 BCAT 抑制剂对 hBCATc 的 IC50 值为 2.35 μM。 BCAT-IN-4 具有抗癌活性，可用于研究胰腺导管腺癌。
T35868	BCAT-IN-2	Others	Others
	BCAT-IN-2 是一种具有口服活性和选择性的线粒体支链氨基转移酶（BCATm）抑制剂，抑制 BCATm 和 BCATc，可用于肥胖症和血脂异常。
T79311	CNBCA
	CNBCA是一种有效的SHP2酶抑制剂，具有选择性和竞争性，IC50值为0.87 μM。该化合物可结合SHP2全长蛋白并抑制其酶活性，进而阻止Akt和ERK1/2的磷酸化，以及抑制BT474和MDA-MB468乳腺癌细胞的生长。CNBCA主要用于乳腺癌的研究。
T40218	BCAT-IN-1
	BCAT-IN-1 是一种有效，选择性和具有口服活性的 BCATm 抑制剂，pIC50值为 7.3。BCAT-IN-1 对 BCATm 的选择性是 BCATc 的 100 倍 (pIC50=5.4)。BCAT-IN-1 可用于代谢疾病的研究。
T37470	Bismuth subcarbonate
	Bismuth subcarbonate, also known as bismuth carbonate oxide, is a versatile semiconductor compound based on bismuth, commonly utilized for its antibacterial properties, as well as in various applications such as sensors, super capacitors, and photocatalysts. Additionally, bismuth subcarbonate serves as a protective agent against gastric acid erosion, particularly in the treatment of gastric ulcers[1][2].
TP2231	HBcAg [Hepatitis B virus] (18-27)	Others	Others
	HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person.
T61012	Bobcat339 hydrochloride
	Bobcat339 hydrochloride 可用于表观遗传学领域，并作为靶向 DNA 甲基化和基因转录的新疗法的起点。它是一种有效的选择性胞嘧啶的 TET 酶的抑制剂，对 TET1和 TET2的 IC50值分别为 33 μM 和 73 μM。

化合物

Cat.No: T14514

Synonym: Disodium bicinchoninate

Target: Others

Cat.No: T6916

Synonym: OICR 9429

Target: Histone Methyltransferase, JAK

BCATc Inhibitor 2

Cat.No: T22043

Target: Others

Cat.No: T5198

Synonym: 盐酸Bobcat339,Bobcat339 hydrochloride

Target: DNA Methyltransferase

Cat.No: T21915

Synonym: Casein Kinase II Inhibitor III, TBCA

Target: Casein Kinase

Cat.No: T77522

Target: Others

Cat.No: T35868

Target: Others

Cat.No: T79311

Cat.No: T40218

Bismuth subcarbonate

Cat.No: T37470

HBcAg [Hepatitis B virus] (18-27)

Cat.No: TP2231

Target: Others

Bobcat339 hydrochloride

Cat.No: T61012

Cat. No.	Product Name	Target	Signaling Pathways
T3604	Sodium dichloroacetate Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯	Apoptosis; Dehydrogenase; Reactive Oxygen Species; PDK	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Sodium dichloroacetate (BCA) 是癌细胞线粒体中的一种代谢调节剂，具有抗癌活性。它抑制丙酮酸脱氢酶激酶，从而导致肿瘤微环境中的乳酸减少。它增加活性氧的产生并促进癌细胞凋亡，还可作为NKCC 抑制剂。
T3158	Harmane Loturine,Harman,Aribine,哈尔满碱	Adrenergic Receptor; Monoamine Oxidase; Imidazoline Receptor	GPCR/G Protein; Neuroscience
	Harmane (Loturine) 是一种在咖啡和烟草烟雾中发现的 β-咔啉生物碱，是有效的神经毒素，可引起严重的动作震颤和精神病学表现。它还是选择性的单胺氧化酶抑制剂，具有致突变作用，对 MAO A/B 的 IC50值分别为 0.5 和 5 μM。

天然产物

Sodium dichloroacetate

Cat.No: T3604

Synonym: Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯

Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK

Cat.No: T3158

Synonym: Loturine,Harman,Aribine,哈尔满碱

Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00735	CXCL13/BCA-1 Protein, Mouse, Recombinant (His) ANGIE,BLR1L,ANGIE2,BLC,SCYB13,BCA1,BCA-1	Mouse	HEK293 Cells
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The pred...
TMPK-00734	CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) ANGIE,ANGIE2,BCA-1,BLR1L,BLC,BCA1,SCYB13	Mouse	HEK293 Cells
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The pred...
TMPK-00017	CXCL13/BCA-1 Protein, Human, Recombinant (hFc) BCA1,BLR1L,BLC,SCYB13,ANGIE2,BCA-1,ANGIE	Human	HEK293 Cells
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The pred...
TMPY-04887	BCA-1 Protein, Human, Recombinant BCA1,BCA-1,SCYB13,ANGIE,BLR1L,chemokine (C...	Human	E. coli
	BCA-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is O43927.
TMPK-00018	CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo) BLC,SCYB13,ANGIE,ANGIE2,BCA-1,BLR1L,BCA1	Human	E. coli
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo) is expressed in E. coli expression system with N-His-Sum...
TMPY-03708	BCA-1 Protein, Canine, Recombinant (His) chemokine (C-X-C motif) ligand 13	Canine	E. coli
	BCA-1 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.1 kDa and the accession number is XP_851619.3.
TMPY-02149	BCA-1 Protein, Cynomolgus, Recombinant (His) chemokine (C-X-C motif) ligand 13	Cynomolgus	E. coli
	BCA-1 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.4 kDa.
TMPY-02191	BLNK Protein, Human, Recombinant (His) BLNK-S,bca,SLP-65,B-cell linker,LY57,SLP65,AGM4,BAS...	Human	HEK293 Cells
	B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 and BLNK, is a cytoplasm and cell membrane protein which contains oneSH2 domain. BLNK is expressed in B-cell lineage and fibroblast cell lines. Highest levels of expression is in the spleen, with lower levels in the liver, kidney, pancreas, small inte...
TMPY-02637	BCAM Protein, Human, Recombinant (His) basal cell adhesion molecule (Lutheran blood group),LU,AU,MS...	Human	HEK293 Cells
	BCAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P50895.
TMPH-01002	BCAP31 Protein, Human, Recombinant (GST) Bap31,BCAP31,p28,DXS1357E,Protein CDM,6C6-AG tumor-...	Human	E. coli
	BCAP31 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.5 kDa and the accession number is P51572.
TMPH-03253	BCAN Protein, Rat, Recombinant (His & Myc) Brevican core protein,Behab,Bcan,Brain-enriched hya...	Rat	Baculovirus Insect Cells
	May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Isoform 2 may function as a chondroitin sulfate-bearing cell surface receptor. BCAN Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 19 kDa and the accession number is P55068.
TMPJ-00491	BCAN Protein, Human, Recombinant (His) Chondroitin Sulfate Proteoglycan 7,BCAN,CSPG7,BEHAB...	Human	HEK293 Cells
	Brevican Core Protein (BCAN) is a secreted protein that belongs to the aggrecan/versican proteoglycan family. BCAN contains one C-type lectin domain, one EGF-like domain, one Ig-like V-type domain, one Sushi (CCP/SCR) domain and two Link domains. BCAN may play a role in the terminally differentiating and the adult nervous system during postnatal development. BCAN could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
TMPH-03252	BCAN Protein, Rat, Recombinant (hFc) Bcan,Behab,BEHAB,Brevican core protein,Brain-enrich...	Rat	HEK293 Cells
	May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Isoform 2 may function as a chondroitin sulfate-bearing cell surface receptor. BCAN Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFC tag. The predicted molecular weight is 44 kDa and the accession number is P55068.
TMPY-00679	BCAM Protein, Human, Recombinant (hFc) basal cell adhesion molecule (Lutheran blood group),AU,MSK19...	Human	HEK293 Cells
	BCAM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83 kDa and the accession number is P50895.
TMPH-02554	BCAT2 Protein, Mouse, Recombinant (His & Myc) Bcat2,BCAT(m),Eca40,Branched-chain-amino-a...	Mouse	E. coli
	Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. BCAT2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.2 kDa and the accession number is O35855.
TMPY-02455	BCAM Protein, Mouse, Recombinant (hFc) 1200005K12Rik,basal cell adhesion molecule (Lutheran blood g...	Mouse	HEK293 Cells
	BCAM Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84 kDa and the accession number is Q9R069.
TMPY-02999	BCAM Protein, Rat, Recombinant (His) basal cell adhesion molecule (Lutheran blood group)	Rat	HEK293 Cells
	BCAM Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.2 kDa and the accession number is Q9ESS6.
TMPJ-00705	BCAS2 Protein, Human, Recombinant (His, T7) BCAS2,DNA Amplified in Mammary Carcinoma 1 Protein,...	Human	E. coli
	Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator ...
TMPK-00558	BCAM Protein, Cynomolgus, Recombinant (His) CD239,MSK19,Lutheran,Gplu,LU	Cynomolgus	HEK293 Cells
	Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
TMPY-02507	BCAM Protein, Mouse, Recombinant (His) Lu,1200005K12Rik,B-CAM,Gplu,basal cell adhesion molecule (Lu...	Mouse	HEK293 Cells
	BCAM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.3 kDa and the accession number is Q9R069.

重组蛋白

CXCL13/BCA-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00735

Species: Mouse

Expression System: HEK293 Cells

CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00734

Species: Mouse

Expression System: HEK293 Cells

CXCL13/BCA-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00017

Species: Human

Expression System: HEK293 Cells

BCA-1 Protein, Human, Recombinant

Cat.No: TMPY-04887

Species: Human

Expression System: E. coli

CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)

Cat.No: TMPK-00018

Species: Human

Expression System: E. coli

BCA-1 Protein, Canine, Recombinant (His)

Cat.No: TMPY-03708

Species: Canine

Expression System: E. coli

BCA-1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-02149

Species: Cynomolgus

Expression System: E. coli

BLNK Protein, Human, Recombinant (His)

Cat.No: TMPY-02191

Species: Human

Expression System: HEK293 Cells

BCAM Protein, Human, Recombinant (His)

Cat.No: TMPY-02637

Species: Human

Expression System: HEK293 Cells

BCAP31 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01002

Species: Human

Expression System: E. coli

BCAN Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03253

Species: Rat

Expression System: Baculovirus Insect Cells

BCAN Protein, Human, Recombinant (His)

Cat.No: TMPJ-00491

Species: Human

Expression System: HEK293 Cells

BCAN Protein, Rat, Recombinant (hFc)

Cat.No: TMPH-03252

Species: Rat

Expression System: HEK293 Cells

BCAM Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00679

Species: Human

Expression System: HEK293 Cells

BCAT2 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02554

Species: Mouse

Expression System: E. coli

BCAM Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02455

Species: Mouse

Expression System: HEK293 Cells

BCAM Protein, Rat, Recombinant (His)

Cat.No: TMPY-02999

Species: Rat

Expression System: HEK293 Cells

BCAS2 Protein, Human, Recombinant (His, T7)

Cat.No: TMPJ-00705

Species: Human

Expression System: E. coli

BCAM Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00558

Species: Cynomolgus

Expression System: HEK293 Cells

BCAM Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02507

Species: Mouse

Expression System: HEK293 Cells

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