Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T22180 | 3F8
化合物3F8
|
159109-11-2 | 98% |
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3F8 是一种具有选择性的 GSK-3β抑制剂,可用作 GSK3 相关疾病的新工具和潜在治疗候选化合物,可用于研究神经系统疾病和癌症。 | ||||
T35556 | GSK-3β inhibitor 8
GSK-3β抑制剂8
|
1139875-74-3 | 98% |
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GSK-3β inhibitor 8是具有有效和选择性的 GSK-3β 抑制剂 ,IC50值为 64 nM。GSK-3β inhibitor 8 是一种噻吩嘧啶衍生物,负调控 Wnt 信号通路,刺激 β 细胞增殖。 | ||||
T61360 | ARN25068
化合物ARN25068
|
2649882-80-2 | 98% |
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ARN25068是三种蛋白激酶(GSK-3β、FYN和DYRK1A)的亚微摩尔抑制剂,可用于治疗tau相关神经系统疾病。 | ||||
T72048 | CDK8-IN-12
化合物CDK8-IN-12
|
2613307-67-6 | 98% |
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CDK8-IN-12 是一种具有选择性、有效性和口服活性的 CDK8 抑制剂(Ki : 14 nM),是一种抗癌剂。CDK8-IN-12 对 GSK-3α、GSK-3β、PCK-θ 具有抑制作用,Ki 分别为 13 nM、4 nM、109 nM。CDK8-IN-12对 MV4-11 细胞显示出抗增殖活性。 | ||||
T15204 | EHT 1610
化合物EHT 1610
|
1425945-60-3 | 98% |
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EHT 1610 是双特异性酪氨酸磷酸化调节酶 (DYRK) 的强效抑制剂,对 DYRK1A 和 DYRK1B 有抑制作用,的 IC50 分别为 0.36 nM 和 0.59 nM。EHT 1610 对白血病具有抑制效应,可调节细胞周期,诱导细胞凋亡。 | ||||
T69188 | Aloisine B
化合物Aloisine B
|
496864-14-3 | 98% |
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Aloisine B is a potent and selective CDK and GSK-3 inhibitor. Highest affinity targets: Glycogen Synthase Kinase-3, Beta (Rattus norvegicus (rat)) (IC50 750.0 nM... | ||||
T11468 | GSK-3 inhibitor 1
化合物 T11468
|
603272-51-1 | 98% |
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GSK-3 inhibitor 1 is a GSK-3 inhibitor. | ||||
TN4424 | Lecanoric acid
化合物 TN4424
|
480-56-8 | 98% |
|
Lecanoric acid shows antioxidant activity with an IC50 value of 79-95 ug/ml, it at 100 ug/ml conc. shows high growth stimulating activity in terms of increased d... | ||||
TN4263 | Isoangustone A
化合物 TN4263
|
129280-34-8 | 98% |
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ... | ||||
TN3319 | 9-Hydroxycanthin-6-one
化合物 TN3319
|
138544-91-9 | 98% |
|
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ... | ||||
T10172 | 5-Iodo-indirubin-3'-monoxime
5-碘靛红-3'-单肟
|
331467-03-9 | 98% |
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5-Iodo-indirubin-3'-monoxime 是一种 GSK-3β、CDK5/P25和CDK1/cyclin B 抑制剂,IC50值分别为 9、20 和 25 nM,与 ATP 竞争性地结合酶的催化位点。 | ||||
T2S0606 | Bakkenolide A
蜂斗菜内酯A
|
19906-72-0 | 98% |
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Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign... | ||||
T10786 | Charantin
化合物 T10786
|
57126-62-2 | 98% |
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Charantin is a steroidal saponin isolated from Momordica charantia. It increases the release of insulin and slowing down gluconeogenesis. Charantin can inhibit G... | ||||
TN4637 | Neogrifolin
化合物 TN4637
|
23665-96-5 | 98% |
|
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ... | ||||
T6139 | A-674563
化合物A-674563
|
552325-73-2 | 98% |
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A674563 是一种口服有效,选择性的Akt1抑制剂,Ki=11 nM。 | ||||
TN2995 | 4,10-Aromadendranediol
化合物 TN2995
|
70051-38-6 | 98% |
|
4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which may be beneficial to the treatm... | ||||
TN2775 | 2-Methoxystypandrone
化合物 TN2775
|
85122-21-0 | 98% |
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm... | ||||
TMA0291 | Dehydroglyasperin D
化合物 TMA0291
|
517885-72-2 | 98% |
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Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h... | ||||
TN4046 | Excisanin A
化合物 TN4046
|
78536-37-5 | 98% |
|
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote... | ||||
T11960 | MBM-55
化合物MBM-55
|
2083622-09-5 | 98% |
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MBM-55 是一种有效的中心体相关激酶 2 (NEK2) 抑制剂,IC50 为 1 nM。 MBM-55 通过诱导细胞周期停滞和凋亡有效抑制癌细胞的增殖。 |