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JZ19 降低细胞内 LDH 和 ROS 水平,并对oxygen-glucose deprivation (OGD) 诱导的心肌细胞损伤展现抗氧化活性。JZ19 通过PI3K-AKT-GSK3β信号通路逆转Isoproterenol诱导的心肌细胞肥大和apoptosis。在小鼠模型中,JZ19 减轻Isoproterenol诱导的心力衰竭。
JZ19 降低细胞内 LDH 和 ROS 水平,并对oxygen-glucose deprivation (OGD) 诱导的心肌细胞损伤展现抗氧化活性。JZ19 通过PI3K-AKT-GSK3β信号通路逆转Isoproterenol诱导的心肌细胞肥大和apoptosis。在小鼠模型中,JZ19 减轻Isoproterenol诱导的心力衰竭。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 待询 | 待询 | |
50 mg | 待询 | 待询 |
JZ19 相关产品
产品描述 | JZ19 reduces intracellular levels of LDH and ROS and demonstrates antioxidant activity against oxygen-glucose deprivation (OGD)-induced myocardial cell damage. It reverses Isoproterenol-induced myocardial cell hypertrophy and apoptosis through the PI3K-AKT-GSK3β signaling pathway. Additionally, JZ19 alleviates Isoproterenol-induced heart failure in mouse models. |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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