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Search Results for " glutamine "

52

抑制剂 & 化合物

14

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8171	Glycyl-glutamine Glycyl-L-glutamine monohydrate,甘氨酰-L-谷氨酰胺一水合物,Glycyl-L-glutamine,Glycylglutamine	Others	Others
	Glycyl-glutamine (Glycyl-L-glutamine monohydrate) 是 β-内啡肽(1-31) 的内源拮抗剂，是β-endorphin 的酶裂解产品。它是一种比谷氨酰胺 (Gln) 稳定的活性神经肽。
T5593	L-Alanyl-L-glutamine L-丙氨酰-L-谷氨酰胺,L-丙氨酸-L-谷氨酰胺,Ala-Gln	Others; Endogenous Metabolite	Metabolism; Others
	L-Alanyl-L-glutamine (Ala-Gln) 是一种由丙氨酸和谷氨酰胺组成的二肽，对抗氧化系统有益，能够减轻炎症，并能够在分解代谢情况下调节热休克蛋白 (HSP) 的反应。
T31944	Glutamine monofluorophosphate L-Glutamine monofluorophosphate,G-MFP
	Glutamine monofluorophosphate is used during the fluorotherapy of osteoporosis.
T64330	Nalpha-Fmoc-L-Glutamine Fmoc-Gln-OH,Fmoc-L-glutamine	Amino Acids and Derivatives	Metabolism
	Nalpha-Fmoc-L-Glutamine (Fmoc-Gln-OH) 是一种谷氨酰胺衍生物。
T36064	N-Oleoyl Glutamine
	N-Oleoyl glutamine is an endogenous N-acyl amine.1,2It is both formed and degraded by peptidase M20 domain-containing 1 (PM20D1), a factor secreted by thermogenic adipose cells. N-Oleoyl glutamine (50 μM) induces mitochondrial uncoupling to increase respiration in C2C12 cells by 64%.3It inhibits capsaicin-induced calcium flux in HEK293A cells co-transfected with transient receptor potential vanilloid 1 (TRPV1) and red fluorescent protein (RFP).2N-Oleoyl glutamine (100 mg/kg) reduces the number o...
T40668	N-Palmitoyl-L-glutamine
	N-Palmitoyl-L-glutamine is a Glutamine derivative.
T31965	Glycotriosyl glutamine Triglc-gln
	Glycotriosyl glutamine is a nephritogenoside analog.
T34678	Sodium phenylacetyl glutamine Antineoplaston AS 2-5
	Sodium phenylacetyl glutamine is a product formed by the conjugation of phenylacetate and glutamine. It is a common metabolite that is naturally occurring in human urine.
T76574	Arginyl-Glutamine
	Arginyl-Glutamine 是一种二肽，可以降低VEGF 水平，并抑制氧诱导视网膜病变小鼠模型中的视网膜新生血管。
T67539	N-Carbobenzyloxy-L-glutamine
	N-Carbobenzyloxy-L-glutamine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67539。
T25454	Glutamamide L-Glutamine amide,Pentanediamide, 2-amino-, (2S)-
	Glutamamide is an anticancer drug.
T12447	Phenylacetylglutamine-D5 NSC 203800-D5,Phenylacetyl-L-glutamine-D5	Others	Others
	Phenylacetylglutamine-D5 is a deuterated form of Phenylacetylglutamine.
T15411	GPNA hydrochloride	Apoptosis; Others	Apoptosis; Others
	GPNA hydrochloride 是一种 γ-谷氨酰转移酶的知名底物，可逆地诱导 A549 细胞凋亡。它是一种特定的谷氨酰胺转运蛋白ASCT2抑制剂，还抑制依赖 Na+的载体，如 SNAT 家族 (SNAT1/2/4/5) 和不依赖 Na+的亮氨酸转运蛋白 LAT1/2。
T32733	L-Glutamic acid, N-nicotinoyl-, disodium salt L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt,N-(3-Pyridinylcarbonyl)glutamine disodium salt
	L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt is a bioactive chemical.
T124414	N-(1-Carboxy-2-phenylethyl)glutamine
	N-(1-Carboxy-2-phenylethyl)glutamine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124414，CAS号为 6810-81-7。
T5345	V-9302	Others	Others
	V-9302 是一种跨膜谷氨酰胺通量的竞争性拮抗剂。它选择性的靶向氨基酸转运体 ASCT2 (SLC1A5)，不影响 ASCT1。它能够阻碍 HEK-293 细胞中由 ASCT2 介导的谷氨酰胺摄取 (IC50=9.6 μM)。
T31824	Fluoroglutamine (2S,4R) FDG
	Fluoroglutamine (2S,4R) is a Glutamine analog, not metabolized in the TCA cycle, but it can be incorporated into proteins and peptides. Fluoroglutamine (2S,4R) can be used as assess transporter (ASCT2) activity or protein synthesis rate.
T33355	Methylseleno carboxyethylglutamine Peptiselene
	Methylseleno carboxyethylglutamine is a bioactive chemical.
T33609	N-Butoxyacetylglutamine Baa-gln
	N-Butoxyacetylglutamine is a metabolite of N-butoxyacetic acid.
T33572	N-Acetylglutaminylglutamine amide NAGGN
	N-Acetylglutaminylglutamine amide, as an unusual dipeptide, can be accumulated during osmotic stress in Rhizobium meliloti.
T34207	Pyroglutamylglutamine diketopiperazine Pglu-glu dkm
	Pyroglutamylglutamine diketopiperazine is a bioactive chemical.
T62560	Sirpiglenastat DRP-104	Glutaminase	Proteases/Proteasome
	Sirpiglenastat (DRP-104) 是一种谷氨酰胺 (glutamine) 拮抗剂，是DON的前药，具有抗肿瘤活性，通过抑制谷氨酰胺代谢和刺激先天性和适应性免疫系统来发挥作用。
T9085	JFD01307SC [(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]	Antibacterial	Microbiology/Virology
	JFD01307SC ([(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]) 是一种谷氨酰胺合成酶抑制剂。它是抗结核剂，可作为 L-谷氨酸盐的模拟物，靶向参与谷氨酰胺生物合成的酶。
T41299	L-Methionine-DL-sulfoximine MSX,MSO	Others	Others
	L-Methionine-DL-sulfoximine (MSO) 抑制谷氨酰胺合成酶，主要在代谢和形态上影响星形胶质细胞。L-Methionine-DL-sulfoximine 可用于惊厥相关研究。
T67865	BJJF078	Glutaminase	Proteases/Proteasome
	BJJF078 是一种氨基哌啶衍生物，是一种有效的重组人和小鼠谷氨酰胺转氨酶 (TG2) 活性的抑制剂，对人和小鼠谷氨酰胺转氨酶的IC50 值分别为 41 和 54 nM。BJJF078 对 TG1 酶有抑制作用，其IC50 为 0.16 μM。 BJJF078 可用于研究多发性硬化症 (MS) 。
T9372	D-Histidine	Mitochondrial Metabolism	Metabolism
	D-Histidine 是一种 L-histidine 的对映体。其中 L-histidine 是婴儿必需的氨基酸，是一种线粒体谷氨酰胺转运的抑制剂。
T11717	JHU395	Apoptosis	Apoptosis
	JHU395 是一种口服生物利用度高的前药，其活性成分是亲脂性谷氨酸拮抗剂（GA，6-叠氮-5-酮-L-去亚硝基赖氨酸）。JHU395 能有效地将DON输送至恶性周围神经鞘瘤（MPNST）的体外和体内模型中，并在MPNST上显现出显著的抗肿瘤活性。此外，JHU395在血浆中表现出良好的稳定性。
T78362	Transglutaminase TG
	Transglutaminase (TG) 是一种硫醇酶，促使蛋白质分子间交联，通过催化谷氨酰胺残基的γ-羧酰胺基团与其他化合物的一级ε-胺基团形成异肽键。该酶在包括凝血、抗菌免疫反应和光合作用在内的多种生理过程中发挥作用。
TP1616L	Hsp70-derived octapeptide acetate Hsp70-derived octapeptide acetate(736171-62-3 free base)	Others	Others
	Hsp70-derived octapeptide acetate (Hsp70-derived octapeptide acetate)(736171-62-3 free base) 是一组含有四肽重复 (TPR) 的蛋白质，已显示与 70 kDa 热休克同源蛋白 (hsc70) 的 C 末端结构域相互作用。在本研究中，含 TPR 的蛋白质，包括 hsc70 相互作用蛋白 (CHIP)、TPR1 和人富含谷氨酰胺的 TPR 含蛋白 (hSGT) 的 C 端，对 DnaJ 和 hsc70 对荧光素酶重折叠的影响进行了调查。
T70016	Methionine sulfoximine
	Methionine sulfoximine (MSO) is an irreversible glutamine synthetase inhibitor. It is the sulfoximine derivative of methionine with convulsant effects.
T27217	Duazomycin Duazomycin A,Acetyl-don,Diazomycin A,NSC 51097
	Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.
T26729	Azotomycin Antibiotic 1719,NSC 56654,Duazomycin B
	Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.
T40064	V-9302 hydrochloride
	V-9302 hydrochloride is a potent and selective competitive antagonist that inhibits transmembrane glutamine flux by specifically targeting the amino acid transporter ASCT2 (SLC1A5), and not ASCT1. In HEK-293 cells, V-9302 hydrochloride effectively inhibits ASCT2-mediated glutamine uptake with an IC50 value of 9.6 μM.
T69068	Aspulvinone H
	Aspulvinone H is a natural inhibitor of glutamic oxaloacetate transaminase 1 (GOT1), suppressing glutamine metabolism, making PDAC cells sensitive to oxidative stress and inhibiting cell proliferation, exhibiting potent in vivo antitumor activity in an SW1990-cell-induced xenograft model.
TP1460	NH2-KLGADTDGEQDQHMTYGGQ-COOH
	NH2-QGGYTMHQDQEGDTDAGLK-COOH is a synthetic peptide chain consisting of a primary amine group attached to lysine and a carboxyl group attached to glutamine.
TP1420	Microtubule-associated protein tau (26-44)
	Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
T37222	GLS1 Inhibitor
	GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50= 0.021 μM).1It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cellsin vitro(GI50= 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model. 1.Finlay, M.R.V., Anderton, M., Bailey, A., et al.Discovery of a thiadiazole-pyridazine-based allosteric glutaminase 1 inhibitor series that demons...
T80566	Temtokibart
	Temtokibart为一种IgG1λ2抗体，靶向IL22RA1并进行人源化处理，由剔除谷氨酰胺合成酶基因的细胞所表达。
T78892	Glutaminase C-IN-2	Glutaminase	Proteases/Proteasome
	GlutaminaseC-IN-2（compound 11）为GAC变构抑制剂，IC50值为10.64 nM。该化合物通过干扰谷氨酰胺代谢，调控细胞代谢产物，进而提高ROS水平，并展现出抗癌活性。
T73885	Methyl gerfelin
	Methyl gerfelin通过与三种关键细胞蛋白乙二醛酶 1 (GLO1)、固醇结合蛋白 2 (SCP2) 和富含谷氨酰胺的四肽重复蛋白 A (SGTA) 结合，抑制破骨细胞的分化。研究表明，Methyl gerfelin是一种与类黄酮相关的强效GLO1抑制剂。
T80559	Duvakitug
	Duvakitug为针对TNFSF15/TL1A的人源IgG1-λ2型单克隆抗体，在CHOK1SV细胞系的内源性谷氨酰胺合成酶(GS)阳性细胞中表达，适用于克罗恩病（Crohn's Disease, CD）研究。
T73458	LWG-301
	LWG-301是一种针对Glutaminase1(GLS1)的变构抑制剂，具有(IC50=7 nM)。通过显著阻断谷氨酰胺代谢并增加细胞内ROS，LWG-301能够诱导细胞凋亡(apoptosis)。在HCT116异种移植模型中，LWG-301展示出中等抗肿瘤活性。
T25455L	Glutaurine aceate	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	含有谷氨酰胺和牛磺酸残基的 Glutaurine aceate 是甲状旁腺的一种口服活性激素。Glutaurine 作为一种激素，从甲状旁腺嗜氧细胞中分离出来。Glutaurine 可用于抗癫痫和抗遗忘的研究。
T77991	Glutaurine TFA Litoralon TFA
	Glutaurine (Litoralon) TFA，含谷氨酰胺与牛磺酸残基，为甲状旁腺源嗜氧细胞分离的口服活性激素。该化合物在抗癫痫与抗健忘症研究中有应用。
T69056	Albizziin
	Albizziin is amino acid analog which acts as a competitive inhibitor of asparagine synthetase with respect to glutamine. Albizziin has been used to isolate mutants of Chinese hamster ovary cells with alterations in levels of the target enzyme. Several classes of mutations can be distinguished on the basis of cross-resistance to beta-aspartyl hydroxamate, another amino acid analog. Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagin...
T72679	GLS1 Inhibitor-4	Glutaminase	Proteases/Proteasome
	GLS1 Inhibitor-4 (compound 41e)作为一种高效的GLS1抑制剂，具有11.86 nM的IC50值。该化合物展现了抗增殖效果、优秀的代谢稳定性以及强大的GLS1结合亲和力。它通过阻断谷氨酰胺代谢和诱导ROS生成，能够引发细胞凋亡并表现出对抗肿瘤的活性。
TP1616	Hsp70-derived octapeptide
	A group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70). In the present study, the effect of the TPR-containing proteins, including the C-terminus
T81825	Melan-A/MART-1 analog [Leu27]-Melan-A, MART-1 (26-35)
	[Leu27]-Melan-A, MART-1 (26-35)是一种具有改良的HLA-A*0201结合能力和增强的免疫原性及抗原性的生物活性肽。该类似物在第27位的Leu替换了Ala，与原生Melan-A (26-35)相比表现出更佳的性能。当序列N端为谷氨酰胺(Q)或谷氨酸(E)时，肽可能会自发形成焦谷氨酰(pGlu)。Q或E到pGlu的转化是自然发生的，pGlu的疏水性γ-内酰胺环被认为可增强针对胃肠道蛋白酶的抵抗力，使得含pGlu的肽成为这类肽的正常子集，在HPLC分析中通常作为评估肽纯度的一部分。
T82504	EE epitope
	EE epitope 是一种具有生物活性的肽，源自小鼠多瘤病毒中间 T 抗原的氨基酸片段（314 至 319）。以 Glu-Glu 为特征的表位肽被广泛用作表位标签。当序列的 N 末端含有谷氨酰胺 (Q) 或谷氨酸 (E) 时，可能会自发形成焦谷氨酰 (pGlu) 肽。Q 或 E 至 pGlu 的转换是自然过程，所形成的疏水性 γ-内酰胺环被认为有助于提高针对胃肠道蛋白酶的肽稳定性。因此，在 HPLC 分析中，这些焦谷氨酰肽作为正常的肽子集纳入考量，用于评估肽的纯度。
T80249	Epsilon-V1-2, Cys-conjugated	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Epsilon-V1-2, Cys-conjugated 是 εPKC 特异性抑制剂，通过阻断 εPKC 与 εRACK 锚定蛋白之间的相互作用，抑制 εPKC 易位及 MARCKS 磷酸化，从而表现生物活性。该肽将半胱氨酸残基接到 C 末端，以形成与载体蛋白的 SS 键。当序列 N 末端为谷氨酰胺 (Q) 或谷氨酸 (E) 时，肽可自发生成焦谷氨酰 (pGlu)。Q或E到pGlu的转化属于自然过程，并且pGlu的疏水性γ-内酰胺环对提高肽对胃肠道蛋白酶的稳定性起关键作用。在 HPLC 分析中，焦谷氨酰肽作为肽纯度的一部分进行检测，视为这类肽的典型子集。

化合物

Glycyl-glutamine

Cat.No: T8171

Synonym: Glycyl-L-glutamine monohydrate,甘氨酰-L-谷氨酰胺一水合物,Glycyl-L-glutamine,Glycylglutamine

Target: Others

L-Alanyl-L-glutamine

Cat.No: T5593

Synonym: L-丙氨酰-L-谷氨酰胺,L-丙氨酸-L-谷氨酰胺,Ala-Gln

Target: Others, Endogenous Metabolite

Glutamine monofluorophosphate

Cat.No: T31944

Synonym: L-Glutamine monofluorophosphate,G-MFP

Nalpha-Fmoc-L-Glutamine

Cat.No: T64330

Synonym: Fmoc-Gln-OH,Fmoc-L-glutamine

Target: Amino Acids and Derivatives

N-Oleoyl Glutamine

Cat.No: T36064

N-Palmitoyl-L-glutamine

Cat.No: T40668

Glycotriosyl glutamine

Cat.No: T31965

Synonym: Triglc-gln

Sodium phenylacetyl glutamine

Cat.No: T34678

Synonym: Antineoplaston AS 2-5

Arginyl-Glutamine

Cat.No: T76574

N-Carbobenzyloxy-L-glutamine

Cat.No: T67539

Cat.No: T25454

Synonym: L-Glutamine amide,Pentanediamide, 2-amino-, (2S)-

Phenylacetylglutamine-D5

Cat.No: T12447

Synonym: NSC 203800-D5,Phenylacetyl-L-glutamine-D5

Target: Others

GPNA hydrochloride

Cat.No: T15411

Target: Apoptosis, Others

L-Glutamic acid, N-nicotinoyl-, disodium salt

Cat.No: T32733

Synonym: L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt,N-(3-Pyridinylcarbonyl)glutamine disodium salt

N-(1-Carboxy-2-phenylethyl)glutamine

Cat.No: T124414

Cat.No: T5345

Target: Others

Fluoroglutamine (2S,4R)

Cat.No: T31824

Synonym: FDG

Methylseleno carboxyethylglutamine

Cat.No: T33355

Synonym: Peptiselene

N-Butoxyacetylglutamine

Cat.No: T33609

Synonym: Baa-gln

N-Acetylglutaminylglutamine amide

Cat.No: T33572

Synonym: NAGGN

Pyroglutamylglutamine diketopiperazine

Cat.No: T34207

Synonym: Pglu-glu dkm

Cat.No: T62560

Synonym: DRP-104

Target: Glutaminase

Cat.No: T9085

Synonym: [(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]

Target: Antibacterial

L-Methionine-DL-sulfoximine

Cat.No: T41299

Synonym: MSX,MSO

Target: Others

Cat.No: T67865

Target: Glutaminase

Cat.No: T9372

Target: Mitochondrial Metabolism

Cat.No: T11717

Target: Apoptosis

Transglutaminase

Cat.No: T78362

Synonym: TG

Hsp70-derived octapeptide acetate

Cat.No: TP1616L

Synonym: Hsp70-derived octapeptide acetate(736171-62-3 free base)

Target: Others

Methionine sulfoximine

Cat.No: T70016

Cat.No: T27217

Synonym: Duazomycin A,Acetyl-don,Diazomycin A,NSC 51097

Cat.No: T26729

Synonym: Antibiotic 1719,NSC 56654,Duazomycin B

V-9302 hydrochloride

Cat.No: T40064

Cat.No: T69068

NH2-KLGADTDGEQDQHMTYGGQ-COOH

Cat.No: TP1460

Microtubule-associated protein tau (26-44)

Cat.No: TP1420

Cat.No: T37222

Cat.No: T80566

Glutaminase C-IN-2

Cat.No: T78892

Target: Glutaminase

Methyl gerfelin

Cat.No: T73885

Cat.No: T80559

Cat.No: T73458

Glutaurine aceate

Cat.No: T25455L

Target: Thyroid hormone receptor(THR)

Cat.No: T77991

Synonym: Litoralon TFA

Cat.No: T69056

GLS1 Inhibitor-4

Cat.No: T72679

Target: Glutaminase

Hsp70-derived octapeptide

Cat.No: TP1616

Melan-A/MART-1 analog

Cat.No: T81825

Synonym: [Leu27]-Melan-A, MART-1 (26-35)

Cat.No: T82504

Epsilon-V1-2, Cys-conjugated

Cat.No: T80249

Target: PKC

Cat. No.	Product Name	Target	Signaling Pathways
T0326	DL-Glutamine Glutamin,DL-Gl,(±)-Glutamine,DL-谷氨酰胺,2-amino-4-carbamoylbutanoic acid	Ferroptosis; Amino Acids and Derivatives; Endogenous Metabolite	Apoptosis; Metabolism
	DL-Glutamine (2-amino-4-carbamoylbutanoic acid) 是一种非必需氨基酸，大量存在于全身并参与许多代谢过程。它由谷氨酸和氨合成，是体内氮的主要载体，是许多细胞的重要能量来源，用于制药和供生物化学研究。
T6468	D-glutamine	Mitophagy; Ferroptosis; Endogenous Metabolite; GluR; Autophagy	Apoptosis; Autophagy; Metabolism; Neuroscience
	D-Glutamine 是有细胞渗透性谷氨酰胺的 D 型立体异构体，是标准遗传密码编码的20种氨基酸之一。
T0326L	L-Glutamine L-Glutamic acid 5-amide,L-谷氨酰胺	Ferroptosis; Endogenous Metabolite; GluR	Apoptosis; Metabolism; Neuroscience
	L-Glutamine (L-Glutamic acid 5-amide) 是在人体中大量存在的一种非必需氨基酸，由谷氨酸和氨合成。它为某些细胞中的氧化提供了碳源。
T0769	Aceglutamide N-乙酰-L-谷氨酰胺,N2-Acetylglutamine,α-N-Acetyl-L-glutamine,乙酰谷酰胺	Amino Acids and Derivatives; Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Aceglutamide (N2-Acetylglutamine) 是一种精神激活剂和促智剂，是氨基酸 L-谷氨酰胺的乙酰衍生物，用于改善记忆和集中注意力。
T5265	Phenylacetylglutamine NSC 203800,N-苯乙酰基-L-谷氨酰胺,Phenyl-Ac-Gln-OH,Phenylacetyl-L-glutamine	Others; Endogenous Metabolite	Metabolism; Others
	Phenylacetylglutamine (NSC 203800) 是结肠微生物的代谢物，源于氨基酸发酵。
T5980	2-Ketoglutaric acid α-酮戊二酸,alpha-酮戊二酸	Tyrosinase; Endogenous Metabolite	Metabolism; Proteases/Proteasome
	2-Ketoglutaric acid 是 Krebs 循环的中间体，可以产生 ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。
T0507	L-Pyroglutamic acid L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline	Others; Endogenous Metabolite	Metabolism; Others
	L-Pyroglutamic acid (pidolic acid) 是 Pyroglutamic acid 的左旋异构体，是人体中具有生物特性的对映异构体。Pyroglutamic acid 是谷胱甘肽代谢中的中间体。
TQ0158	Azaserine CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine	Others; Antibiotic	Microbiology/Virology; Others
	Azaserine (CI-337) 是一种从链霉菌属中分离出来的肿瘤抑制抗生素，可作为谷氨酰胺氨基转移酶的抑制剂。
T4813	L-Citrulline	Endogenous Metabolite	Metabolism
	L-Citrulline 是一种氨基酸，源自于精氨酸-瓜氨酸途径获得的 l-精氨酸，或脯氨酸、谷氨酰胺和谷氨酸盐的分解代谢过程中产生的鸟氨酸。
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
T4826	L-Histidine monohydrochloride monohydrat	Others; Endogenous Metabolite	Metabolism; Others
	L-Histidine monohydrochloride monohydrat 是一种 α-氨基酸。 L-异构体是 22 种蛋白质氨基酸之一，即蛋白质的组成部分。
T81794	Micromonosporamide A
	Micromonosporamide A exhibits glutamine-dependent antiproliferative activity. Micromonosporamide A体现了以谷氨酰胺为依赖的抗增殖活性。
T78485	D-Glucosamine 6-phosphate Glucosamine-6-phosphate	Endogenous Metabolite	Metabolism
	D-Glucosamine 6-phosphate为内源性代谢分子，谷氨酰胺果糖-6-磷酸氨基转移酶(GFAT)介导合成。该化合物常用于糖尿病研究领域。
T36179	Aspulvinone O
	Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulvinone O inhibits aspartate transaminase 1 (GOT1; Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM).2 It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5 mg/kg) redu...

天然产物

Cat.No: T0326

Synonym: Glutamin,DL-Gl,(±)-Glutamine,DL-谷氨酰胺,2-amino-4-carbamoylbutanoic acid

Target: Ferroptosis, Amino Acids and Derivatives, Endogenous Metabolite

Cat.No: T6468

Target: Mitophagy, Ferroptosis, Endogenous Metabolite, GluR, Autophagy

Cat.No: T0326L

Synonym: L-Glutamic acid 5-amide,L-谷氨酰胺

Target: Ferroptosis, Endogenous Metabolite, GluR

Cat.No: T0769

Synonym: N-乙酰-L-谷氨酰胺,N2-Acetylglutamine,α-N-Acetyl-L-glutamine,乙酰谷酰胺

Target: Amino Acids and Derivatives, Endogenous Metabolite, Autophagy

Phenylacetylglutamine

Cat.No: T5265

Synonym: NSC 203800,N-苯乙酰基-L-谷氨酰胺,Phenyl-Ac-Gln-OH,Phenylacetyl-L-glutamine

Target: Others, Endogenous Metabolite

2-Ketoglutaric acid

Cat.No: T5980

Synonym: α-酮戊二酸,alpha-酮戊二酸

Target: Tyrosinase, Endogenous Metabolite

L-Pyroglutamic acid

Cat.No: T0507

Synonym: L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline

Target: Others, Endogenous Metabolite

Cat.No: TQ0158

Synonym: CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine

Target: Others, Antibiotic

Cat.No: T4813

Target: Endogenous Metabolite

5'-Guanylic acid disodium salt

Cat.No: T4901

Synonym: Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5

Target: Others, Endogenous Metabolite

L-Histidine monohydrochloride monohydrat

Cat.No: T4826

Target: Others, Endogenous Metabolite

Micromonosporamide A

Cat.No: T81794

D-Glucosamine 6-phosphate

Cat.No: T78485

Synonym: Glucosamine-6-phosphate

Target: Endogenous Metabolite

Cat.No: T36179

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