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67

抑制剂 & 化合物

16

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T3042	JAK2 Inhibitor V JAK2 Inhibitor V Z3,Z3	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK2 Inhibitor V (JAK2 Inhibitor V Z3) 是一种新型的 Jak2 特异性抑制剂，以剂量依赖性方式抑制 Jak2-V617F 和 Jak2-WT 自磷酸化。
T6005	Z-DEVD-FMK Caspase-3 Inhibitor	Caspase	Apoptosis; Proteases/Proteasome
	Z-DEVD-FMK (Caspase-3 Inhibitor) 是一种选择性、不可逆的 Caspase-3 抑制剂，IC50为 18 μM。它也抑制 caspase-6、caspase-7、caspase-8 和 caspase-10。
T10824	cis-Urocanic acid cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid,顺式-尿刊酸	5-HT Receptor	GPCR/G Protein; Neuroscience
	cis-Urocanic acid ((E)-Urocanic acid) 是一种 5-HT2A 受体激动剂，cis-Urocanic acid 与 5-HT 受体结合的Kd 为 4.6 nM。cis-Urocanic acid 是一种免疫调节剂，通过与 5-HT2A 受体结合而诱导免疫抑制。
T21503	(E/Z)-Zotiraciclib (E/Z)-TG02,(E/Z)-SB1317	FLT; JAK; CDK	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	(E/Z)-Zotiraciclib ((E/Z)-TG02) 是一种 CDK2、JAK2和FLT3的抑制剂，IC50分别为 13、73 和 56 nM。
T9178	(E/Z)-GSK-3β inhibitor 1 GSK-3β inhibitor 1	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	(E/Z)-GSK-3β inhibitor 1 是 (E)-GSK-3β inhibitor 1 和 (Z)-GSK-3β inhibitor 1 的消旋体。它是一种糖原合成酶激酶 3β (GSK-3β)的抑制剂，可其对 GSK-3β 的 IC50=4.9 nM，用于糖尿病的研究。
T5135	Flupentixol dihydrochloride 盐酸氟哌噻吨,Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Flupentixol dihydrochloride 是噻克西酮类试剂，能够用于研究精神分裂症以及抗焦虑和抑郁障碍。
T39869	(Z)-2-Bromo-3-methyl-2-butenedioic acid cis-2-Bromo-3-methylbutenendioic acid,(Z)-2-溴-3-甲基-2-丁二酸
	(Z)-2-Bromo-3-methyl-2-butenedioic acid is a brominated haloacid that acts as a disinfection byproduct (DBP) in finished drinking waters.
T35291	Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene
	Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene 是 Methyl eugenol (ME) 的氟类似物，是东方果蝇 B. dorsalis 的引诱剂。E 型异构体的活性是Z型异构体 Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene 的两倍。
T12302	OMDM-1 (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide	Endogenous Metabolite	Metabolism
	OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) 是有效选择性的代谢稳定 anandamide 细胞摄取抑制剂，Ki=为2.4 μM。
T2340	AC1NS4RE	Tyrosinase	Proteases/Proteasome
	是一种化学合成中的砌块
T37336	N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T12628	(R)-MG-132 (S,R,S)-(-)-MG-132,N-[(苯基甲氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-D-亮氨酰胺,Z-Leu-D-leu-leu-al	Proteasome	Proteases/Proteasome; Ubiquitination
	(R)-MG-132 (Z-Leu-D-leu-leu-al) 是一种 MG-132 的对映异构体，是一种蛋白酶体 (proteasome) 抑制剂，细胞毒性比 MG-132 弱，是一种比 MG-132 更有效的proteasome 抑制剂。
T30626	Butirosamine Z-1159-3
	Butirosamine is a biochemical.
T60059	methyl (Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate
	methyl(Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate 是一种有用的化合物，可用于合成多种有机化合物。
T81609	omega-3 Arachidonic acid ethyl ester (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester
	omega-3 Arachidonic Acid ethyl ester 是一种少见的多不饱和脂肪酸，饮食来源稀少。ω-3脂肪酸对婴幼儿生长发育极为重要，能够帮助预防心脏病、血栓、高血压及炎症和自身免疫性疾病。该化合物在人血小板膜中通过抑制花生四烯酰辅酶A合成酶发挥作用，Ki值达到14 μM；同时在小牛脑提取物中也表现出抑制作用，IC50大约5 μM。omega-3 Arachidonic Acid ethyl ester 作为游离酸的亲脂性更强的形式，具备独特的生物活性。
T125873	(Z)-3-Hydroxy-5-methoxystilbene
	(Z)-3-Hydroxy-5-methoxystilbene 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125873。
T64423	(Z)-[2,3’-Biindolinylidene]-2’,3-dione
	(Z)-[2,3’-Biindolinylidene]-2’,3-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64423，CAS号为 906748-38-7。
T67667	Ethyl (Z)-3-aminobut-2-enoate
	Ethyl (Z)-3-aminobut-2-enoate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67667。
T83963	Z-DEVD-FMK Caspase-3 Inhibitor
	Z-DEVD-FMK Caspase-3 Inhibitor 是一种可渗透细胞膜的、不可逆的 caspase-3/CPP32 抑制剂，能够抑制肿瘤细胞的凋亡。在动物体内，它在大鼠发作后的海马区具有神经保护作用，且显著减少创伤后的细胞凋亡，并在诱发的大鼠创伤性脑损伤之前和之后改善神经学恢复情况。
T124104	3-O-(2'E,4'Z-Decadienoyl)ingenol
	3-O-(2'E,4'Z-Decadienoyl)ingenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124104。
T124424	3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol
	3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124424。
T125709	3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol
	3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125709。
T126203	1,2-Dinor-3-oxo-6,10-farnesadien-14-oic acid; Z-Fo
	1,2-Dinor-3-oxo-6,10-farnesadien-14-oic acid; Z-Fo 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126203，CAS号为 1217271-08-3。
T65586	(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
	(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65586，CAS号为 356068-93-4。
T65075	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate
	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65075，CAS号为 17110-51-9。
T21617	MG-115 Z-LL-Nva-CHO	Proteasome	Proteases/Proteasome; Ubiquitination
	MG-115 (Z-LL-Nva-CHO) 是一种有效且可逆的蛋白酶体抑制剂，对20S 和26S 蛋白酶体的 Ki 值分别为 21 nM 和 35 nM。MG-115 特异性抑制蛋白酶体的胰凝乳蛋白酶样活性，诱导 p53 依赖性细胞凋亡。
T8799	(E/Z)-IT-603 IT603	Others; NF-κB	NF-κB; Others
	(E/Z)-IT-603 是一种c-Rel 抑制剂，其IC50=3 μM。它是 E-IT-603 和 Z-IT-603的混合物。它具有抗癌作用。它有望作为调节剂调节移植物抗宿主病和恶性病中的 T 细胞反应。
T60624	(E/Z)-AG490
	(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) 是异构体 (E)-AG490 和 (Z)-AG490 的外消旋体。(E)-AG490 是一种可抑制EGFR，Stat-3和JAK2/3的酪氨酸激酶抑制剂。
T38278	9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic Acid
	9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic acid is an ω-3 very long-chain polyunsaturated fatty acid. It has been used to study the desaturation and elongation of ω-3 polyunsaturated fatty acids. It is elongated to form C26:5 or acted on by δ6 desaturase to form C24:6. 9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic acid is found at low levels in mouse brain and spleen and levels decrease in the brain and spleen of old and exceptionally old mice.
T37371	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid
	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not known, dietary intake of n-3 long-chain PUFAs provides potential health benefits.
T80659	Z-YVAD-CMK	Caspase	Apoptosis; Proteases/Proteasome
	Z-YVAD-CMK为一种针对caspase-1及caspase-3的抑制剂。
T69491	(E/Z)-Ensifentrine
	(E/Z)-Ensifentrine is a potent and selective PDE3/4 inhibitor. (E/Z)-Ensifentrine acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effects. It is being developed by Verona Pharma as a potential treatment for asthma and hay fever, and is currently in clinical trials.
T37634	17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
	Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).
T67534	Z-Asn-OH
	Z-Asn-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67534，CAS号为 2304-96-3。
T67545	Z-Thr-OH
	Z-Thr-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67545，CAS号为 19728-63-3。
T65187	FMOC-D-LYS(Z)-OH
	FMOC-D-LYS(Z)-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65187，CAS号为 110990-07-3。
T61890	(E/Z)-BIO-acetoxime
	(E/Z)-BIO-acetoxime 是有效的，选择性的GSK-3α/β 抑制剂。对于GSK-3α/β，CDK5/p25，CDK2/cyclin A 和CDK1/cyclin B 的IC50分别为10nM，2.4μM, 4.3μM, 63μM。
T67386	Olanzapine Thiolactam Impurity
	(Z)-1-(4-(4-Methylpiperazin-1-yl)-2-thioxo-1H-benzo[b][1,4]diazepin-3(2H)-ylidene)propan-2-one 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67386。
T36999	7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
	Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to b...
T74044	Z-Pro-prolinal
	Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) 是一种特异的，具有口服活性的脯氨酰寡肽酶 (PREP) 抑制剂，对于猪 PREP 的 IC50为 0.4 nM。
T76232	Z-DEVD-AMC
	Z-DEVD-AMC 是一种选择性 caspase-3 底物，可通过荧光光谱法测量。 AMC 可用作基于 AMC 的酶底物 (包括基于 AMC 的半胱天冬酶底物) 的荧光参考标准。
T61379	Anticancer agent 30
	Anticancer agent 30 (compound 6f-Z) is a potent anticancer compound. It belongs to the class of 3-arylidene-2-oxindole derivatives and acts as a selective inhibitor of CDK2. Extensive research has demonstrated its significant anticancer activity, making it a promising candidate for cancer treatment [1].
T78119	Z-L(D-Val)G-CHN2	HSV	Microbiology/Virology
	Z-L(D-Val)G-CHN2（即Z-LVG-CHN2）是半胱氨酸蛋白酶抑制剂的异构体，作为一种三肽衍生物，模仿了人体半胱氨酸蛋白酶结合中心的部分结构。它可以抑制HSV，并且能有效阻断SARS-COV-2的3CL pro蛋白酶，从而抑制病毒活性（EC50=190 nM），但对脊髓灰质炎病毒复制无显著作用。
T83761	12-oxo-9(Z)-Dodecenoic Acid 12-oxo-9-cis-Dodecenoic Acid,12-keto-9Z-Dodecenoic Acid
	12-oxo-9(Z)-Dodecenoic acid 是一种 ω-oxoacid 和 ω-6 PUFA 亚麻酸及ω-3 PUFA α-亚麻酸的代谢产物。通过植物中的脂氧合酶产生的13-羟基过氧化物中间体，由过氧化物裂解酶形成。12-oxo-9(Z)-Dodecenoic acid (100 µM) 对植物病原真菌 P. parasitica 有活性。
T21783	AG-183
	(Z)-Tyrphostin A51 是 Lanoconazole A51 的 Z 构型形式。Tyrphostin A51 是一种有效的蛋白酪氨酸激酶 (PTK)抑制剂，以剂量依赖性方式抑制原代星形胶质细胞培养物中 [3H]牛磺酸的体积敏感释放。Tyrphostin A51 显着降低细胞酪氨酰磷酸化水平。Tyrphostin A51 抑制基础和 EGF 诱导的人骨细胞增殖。
T36077	cis-Parinaric Acid cis-Parinaric Acid,α-Parinaric Acid
	cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical rainforest tree indigenous to Fiji. Makita seeds are inedible, and this toxicity may be due at least in part to the unstable conjugated fatty acids, including cis-parinaric acid, contained wit...
T35854	9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
	9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co...
T36887	8(E),10(E),12(Z)-Octadecatrienoic Acid
	8(E),10(E),12(Z)-Octadecatrienoic acid is a conjugated polyunsaturated fatty acid (PUFA) that has been found inC. officinalisseed oil and has anticancer activity.1,2,3It inhibits the growth of Caco-2 cells when used at concentrations ranging from 10 to 50 μM.28(E),10(E),12(Z)-Octadecatrienoic acid (10 μM) induces formation of thiobarbituric acid reactive substances (TBARS) and apoptosis in DLD-1 colorectal adenocarcinoma cells.3It also inhibits prostaglandin biosynthesis in sheep vesicular gland...
T37006	Previridicatumtoxin
	Previridicatumtoxin is a fungal metabolite that has been found inP. aethiopicumand has diverse biological activities.1,2It is an intermediate in the biosynthesis of the mycotoxin viridicatumtoxin . Previridicatumtoxin is active against methicillin-resistantS. aureus(MRSA) and vancomycin-resistantE. faecalis(IC50s = 4.4 and 4.8 μM, respectively), as well asC. albicansandS. cerevisiae(MIC = 32 μg/ml for both).2,1It is cytotoxic to NCI H460, KB-3-1, and SW620 cancer cells (IC50s = 5.3, 4.1, and 6 μ...
T37335	N-3-hydroxybutyryl-L-Homoserine lactone
	N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.1,2 It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.3 \|1. Purohit, A.A., Johansen, J.A., Hansen, H., et al. Presence of acyl-homoserine lactones in 57 members of the Vibrionaceae family. J. Appl. Microbiol. 115(3), 835-847 (2013).\|2. Feng, Z., Sun,...

化合物

JAK2 Inhibitor V

Cat.No: T3042

Synonym: JAK2 Inhibitor V Z3,Z3

Target: JAK

Cat.No: T6005

Synonym: Caspase-3 Inhibitor

Target: Caspase

cis-Urocanic acid

Cat.No: T10824

Synonym: cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid,顺式-尿刊酸

Target: 5-HT Receptor

(E/Z)-Zotiraciclib

Cat.No: T21503

Synonym: (E/Z)-TG02,(E/Z)-SB1317

Target: FLT, JAK, CDK

(E/Z)-GSK-3β inhibitor 1

Cat.No: T9178

Synonym: GSK-3β inhibitor 1

Target: GSK-3

Flupentixol dihydrochloride

Cat.No: T5135

Synonym: 盐酸氟哌噻吨,Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride

Target: Dopamine Receptor

(Z)-2-Bromo-3-methyl-2-butenedioic acid

Cat.No: T39869

Synonym: cis-2-Bromo-3-methylbutenendioic acid,(Z)-2-溴-3-甲基-2-丁二酸

Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene

Cat.No: T35291

Cat.No: T12302

Synonym: (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide

Target: Endogenous Metabolite

Cat.No: T2340

Target: Tyrosinase

N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone

Cat.No: T37336

Cat.No: T12628

Synonym: (S,R,S)-(-)-MG-132,N-[(苯基甲氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-D-亮氨酰胺,Z-Leu-D-leu-leu-al

Target: Proteasome

Cat.No: T30626

Synonym: Z-1159-3

methyl (Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate

Cat.No: T60059

omega-3 Arachidonic acid ethyl ester

Cat.No: T81609

Synonym: (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester

(Z)-3-Hydroxy-5-methoxystilbene

Cat.No: T125873

(Z)-[2,3’-Biindolinylidene]-2’,3-dione

Cat.No: T64423

Ethyl (Z)-3-aminobut-2-enoate

Cat.No: T67667

Z-DEVD-FMK Caspase-3 Inhibitor

Cat.No: T83963

3-O-(2'E,4'Z-Decadienoyl)ingenol

Cat.No: T124104

3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol

Cat.No: T124424

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Cat.No: T125709

1,2-Dinor-3-oxo-6,10-farnesadien-14-oic acid; Z-Fo

Cat.No: T126203

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Cat.No: T65586

(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate

Cat.No: T65075

Cat.No: T21617

Synonym: Z-LL-Nva-CHO

Target: Proteasome

Cat.No: T8799

Synonym: IT603

Target: Others, NF-κB

Cat.No: T60624

9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic Acid

Cat.No: T38278

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid

Cat.No: T37371

Cat.No: T80659

Target: Caspase

(E/Z)-Ensifentrine

Cat.No: T69491

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Cat.No: T37634

Cat.No: T67534

Cat.No: T67545

FMOC-D-LYS(Z)-OH

Cat.No: T65187

(E/Z)-BIO-acetoxime

Cat.No: T61890

Olanzapine Thiolactam Impurity

Cat.No: T67386

7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Cat.No: T36999

Cat.No: T74044

Cat.No: T76232

Anticancer agent 30

Cat.No: T61379

Z-L(D-Val)G-CHN2

Cat.No: T78119

Target: HSV

12-oxo-9(Z)-Dodecenoic Acid

Cat.No: T83761

Synonym: 12-oxo-9-cis-Dodecenoic Acid,12-keto-9Z-Dodecenoic Acid

Cat.No: T21783

cis-Parinaric Acid

Cat.No: T36077

Synonym: cis-Parinaric Acid,α-Parinaric Acid

9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

Cat.No: T35854

8(E),10(E),12(Z)-Octadecatrienoic Acid

Cat.No: T36887

Previridicatumtoxin

Cat.No: T37006

N-3-hydroxybutyryl-L-Homoserine lactone

Cat.No: T37335

Cat. No.	Product Name	Target	Signaling Pathways
TN2326	(Z)-Butylidenephthalide (Z)-3-Butylidenephthalide	Glucosidase	Metabolism
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) 具有抗肿瘤和降血糖作用，能有效抑制胶质瘤的肿瘤生长，抑制 R-葡萄糖苷酶活性。
TN6362	(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one
	(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6362，CAS号为 856007-75-5。
T4867	Erucic acid Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid	PI3K; Endogenous Metabolite	Metabolism; PI3K/Akt/mTOR signaling
	Erucic acid (13(Z)-Docosenoic Acid) 是单不饱和脂肪酸，分离自萝卜的种子。Erucic acid 可以容易地穿过血脑屏障，使大脑中长链脂肪酸的积累正常化。Erucic acid 能够改善认知障碍并有效预防痴呆。
T5S1285	(+)-(3R,8S)-Falcarindiol Falcarindiol,镰叶芹二醇	Others	Others
	(+)-(3R,8S)-Falcarindiol 是一种从胡萝卜中得到的聚乙炔，有抗炎、抗肿瘤和抗脂质过氧化活性。它具有抗分歧杆菌作用，对Mycobacterium tuberculosisH37Ra 的 MIC 和 IC50值分别为 24 μM 和 6 μM。
TN3255	7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone	Others	Others
	7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone shows diacylglycerol acyltransferase (DGAT)1 inhibition with IC(50) values of 47.0 microM (for rat liver microsomes) and 160.7 microM (for HepG2 cell microsomes),
T6212	Combretastatin A4 CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09	Microtubule Associated	Cytoskeletal Signaling
	Combretastatin A4 (CA4) 是一种微管靶向剂，可结合 β-tubulin，Kd 值为 0.4 μM。
T22295	cis-3-Hexen-1-ol 叶醇,Leaf alcohol,(Z)-3-Hexen-1-ol	Others	Others
	cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) 是发现于许多新鲜水果和蔬菜中的一种绿色草味化合物，常用作加工食品的附加风味剂，以提供新鲜的绿色品质，也是多种昆虫的引诱剂。
T83660	3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic Acid C18:5 n-3,C18:5(3Z,6Z,9Z,12Z,15Z),all-cis-3,6,9,12,15-Octadecapentaenoic Acid
	3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic acid 是一种在 G. kowalevskii 中发现的微藻 PUFA，常作为微藻和甲藻的化学分类生物标志物使用。
T83517	(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate
	(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate (compound 7a) 是一种特定立体化学配置的二萜类化合物。
T5574	Guggulsterone Guggulsterone E&Z,香胶甾酮	Apoptosis; FXR; Akt; Caspase; JNK; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Guggulsterone (Guggulsterone E&Z) E&Z 是来自Commiphora wightii 树中树胶脂的植物甾醇。它通过下调抗细胞凋亡基因产物，调节细胞周期蛋白，激活caspases，JNK，抑制Akt，抑制多种肿瘤细胞的生长并诱导细胞凋亡。它是法尼醇 X 受体拮抗剂，可降低 CDCA 诱导的 FXR 活化。
TN1909	Malvidin-3-glucoside chloride 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride	Others	Others
	Malvidin-3-glucoside chloride (Oenin chloride) 是一种主要的葡萄酒花青素，能够调节大脑突触可塑性和外周炎症，促进应激反应的发生。
T38330	Collinin
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...
T37451	Stachybotrysin B
	Stachybotrysin B is a fungal metabolite originally isolated from S. chartarum and has antiviral and anticancer activities.1,2 It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM).1 Stachybotrysin B is cytotoxic to K562, HeLa, and HL-60 cells (IC50s = 21.72, 39.63, and 18.5 μM, respectively).2 \|1. Zhao, J., Feng, J., Tan, Z., et al. Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. J. Nat. Prod. 80(6), 1819-1826 (2017).\|2. Ma, X.-h., Zhen...
T36448	(E)-Ajoene
	(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth...
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1 1.Balan, J., Ebringer, L., Nemec, P., et al.Ant...

天然产物

(Z)-Butylidenephthalide

Cat.No: TN2326

Synonym: (Z)-3-Butylidenephthalide

Target: Glucosidase

(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one

Cat.No: TN6362

Cat.No: T4867

Synonym: Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid

Target: PI3K, Endogenous Metabolite

(+)-(3R,8S)-Falcarindiol

Cat.No: T5S1285

Synonym: Falcarindiol,镰叶芹二醇

Target: Others

7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone

Cat.No: TN3255

Target: Others

Combretastatin A4

Cat.No: T6212

Synonym: CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09

Target: Microtubule Associated

cis-3-Hexen-1-ol

Cat.No: T22295

Synonym: 叶醇,Leaf alcohol,(Z)-3-Hexen-1-ol

Target: Others

3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic Acid

Cat.No: T83660

Synonym: C18:5 n-3,C18:5(3Z,6Z,9Z,12Z,15Z),all-cis-3,6,9,12,15-Octadecapentaenoic Acid

(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate

Cat.No: T83517

Cat.No: T5574

Synonym: Guggulsterone E&Z,香胶甾酮

Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy

Malvidin-3-glucoside chloride

Cat.No: TN1909

Synonym: 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride

Target: Others

Cat.No: T38330

Cat.No: T37452

Stachybotrysin B

Cat.No: T37451

Cat.No: T36448

Cat.No: T35750

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