Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T20232 | Kazinol B
小构树醇B
|
99624-27-8 | 98% |
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Kazinol B 是一氧化氮(NO)产生的抑制剂,是一种具有二甲基吡喃环的异戊烯化黄烷。Kazinol B 通过激活胰岛素-Akt 信号途径和AMPK,增强葡萄糖摄取,从而改善胰岛素敏感性。Kazinol B 刺激脂肪素的基因表达和分泌,可用于研究糖尿病。 | ||||
TN3042 | 4-Hydroxycinnamamide
化合物 TN3042
|
194940-15-3 | 98% |
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases. | ||||
TN5013 | Shizukaol D
化合物 TN5013
|
142279-42-3 | 98% |
|
Shizukaol D exerts a growth inhibition effect on liver cancer cells in a dose- and time-dependent manner by modulating wnt signalling pathway. Shizukaol D may be... | ||||
T10105 | 3α-Hydroxymogrol
3α-羟基罗汉果醇
|
1343402-73-2 | 98% |
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3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle. It is a potent AMPK activator and enhances AMPK phosphorylation. | ||||
T11570 | HL271
化合物 T11570
|
1422365-52-3 | 98% |
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HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment. | ||||
T22460 | XMD-17-51
化合物XMD-17-51
|
1628614-50-5 | 98% |
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XMD-17-51 是一种有效且高度选择性的 NUAK1 抑制剂。 | ||||
TN4382 | Kazinol A
化合物 TN4382
|
99624-28-9 | 98% |
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Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M ag... | ||||
T10312 | Ampkinone
化合物 T10312
|
1233082-79-5 | 98% |
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Ampkinone is an indirect AMPK activator. | ||||
TL0014 | Pinusolide
化合物 TL0014
|
31685-80-0 | 98% |
|
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a... | ||||
T14149 | AICAR phosphate
化合物 T14149
|
681006-28-0 | 98% |
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AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism. It inhibits proinf... | ||||
TN1868 | Ligupurpuroside A
紫茎女贞苷 A
|
147396-01-8 | 98% |
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Ligupurpuroside A has antioxidant,and hypolipidemic effects, it can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol/L. | ||||
T1456 | Doxorubicin(Doxorubicin hydrochloride is in stock)
阿霉素
|
23214-92-8 | 98% |
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Doxorubicin 是一种有细胞毒性的蒽环类抗生素,具有肿瘤化疗作用。它抑制DNA 拓扑异构酶 I 和拓扑异构酶 II,IC50分别为0.8 μM 和2.67 μM,从而抑制 DNA 复制。它下调AMPK 的基础磷酸化以及下游 acetyl-CoA 羧化酶。它诱导凋亡和自噬 。 | ||||
T16113 | ML753286
化合物 T16113
|
1699720-89-2 | 98% |
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ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (... | ||||
TN1870 | Ligupurpuroside C
紫茎女贞苷 C
|
1194056-33-1 | 98% |
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Ligupurpuroside C can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol/L. | ||||
T16166 | N-[(4-Aminophenyl)methyl]adenosine
N-[(4-氨基苯基)甲基]腺苷
|
95523-13-0 | 98% |
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N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase). | ||||
TN1670 | Ganodermanondiol
灵芝酮二醇
|
107900-76-5 | 98% |
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Ganodermanondiol exhibits potent cytoprotective effects on t-BHP-induced hepatotoxicity in human liver-derived HepG2 cells, presumably through Nrf2-mediated anti... | ||||
TN5431 | Icariside E4
化合物Icariside E4
|
126253-42-7 | 98% |
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Icariside E4是一种从小叶榆中提取得到天然化合物, 通过AMPK 磷酸化和抑制HepG1细胞中MID1IP2的低脂化作用。Icariside E4具有抗伤害,抗氧化,抗阿尔茨海默氏症和抗炎作用,抑制了SREBP-1c,肝脏X 受体-α(LXR)和FASN 在HepG2细胞中从头脂肪生成的表达。Icarisi... | ||||
T13371 | YM-53601 free base
化合物 T13371
|
182959-28-0 | 98% |
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YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents. | ||||
T3881 | Vaccarin
王不留行黄酮苷
|
53452-16-7 | 98% |
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Vaccarin 是从王不留行中提取的一种黄酮糖苷,可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。 | ||||
T5552 | Methyl cinnamate
肉桂酸甲酯
|
103-26-4 | 98% |
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Methyl cinnamate 是花椒的有效成分,也是一种天然香料。它是一种防止食品褐变的酪氨酸酶抑制剂,具有抗菌活性。它通过由 CaMKK2-AMPK 信号途径介导的机制具有抗脂活性。 |