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Microtubule Associated

Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
TargetMol
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Cat. No. Product Name CAS No. Purity Chemical Structure
T13807 OSIP-486823
化合物OSIP-486823
200803-37-8 98.59%
TargetMol Chemical Structure OSIP-486823
OSIP-486823(CP248) 是一种新型有效的微管干扰剂,对蛋白激酶 G (PKG) 和微管均具有亲和力。
T36848 Combretastatin A-1
康普瑞汀A-1
109971-63-3 97.49%
TargetMol Chemical Structure Combretastatin A-1
Combretastatin A-1 是一种有效的微管抑制剂,具有抗肿瘤和抗血管活性,通过微管蛋白解聚介导的 AKT 失活抑制 Wnt/β-catenin 通路发挥作用,可用于研究肝癌。
T16997 Tasidotin hydrochloride
化合物 T16997
623174-20-9 98%
TargetMol Chemical Structure Tasidotin hydrochloride
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
T17229 Verubulin
化合物 T17229
827031-83-4 98%
TargetMol Chemical Structure Verubulin
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
T6721 Vinblastine
长春质碱
865-21-4 98%
TargetMol Chemical Structure Vinblastine
Vinblastine 抑制微管形成并抑制 nAChR 活性,IC50 为 8.9 μM,用于治疗某些类型的癌症。
TQ0112 Tubulysin A
化合物Tubulysin A
205304-86-5 98%
TargetMol Chemical Structure Tubulysin A
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
T13227 Tubulin inhibitor 1
化合物 T13227
2237054-53-2 98%
TargetMol Chemical Structure Tubulin inhibitor 1
Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
T10428 AZ82
化合物 T10428
1449578-65-7 98%
TargetMol Chemical Structure AZ82
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
T11712 Jasplakinolide
肌动蛋白多聚化肽
102396-24-7 98%
TargetMol Chemical Structure Jasplakinolide
Jasplakinolide(Jaspamide) 是一种来自海洋海绵 (marine sponge) 的天然环状肽,是一种有效的肌动蛋白聚合反应 (actin polymerization) 诱导剂。Jasplakinolide 具有抗真菌和抗肿瘤活性,可以稳定先前存在的肌动蛋白丝。Jasplakinolide 与鬼笔...
T12805 S-methyl DM1
化合物 T12805
912569-84-7 98%
TargetMol Chemical Structure S-methyl DM1
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
T12052 Mivobulin
化合物 T12052
122332-18-7 98%
TargetMol Chemical Structure Mivobulin
Mivobulin is an inhibitor of tubulin .
T13901 SS28
化合物 T13901
141172-08-9 98%
TargetMol Chemical Structure SS28
SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
T16543 Pironetin
化合物 T16543
151519-02-7 98%
TargetMol Chemical Structure Pironetin
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
T6722 Vinflunine Tartrate
长春氟宁酒石酸盐
1201898-17-0 98%
TargetMol Chemical Structure Vinflunine Tartrate
Vinflunine Tartrate 是一种独特的新型长春花生物碱,具有抑制有丝分裂和微管蛋白相互作用活性的特性。
T16387 Ombrabulin
化合物 T16387
181816-48-8 98%
TargetMol Chemical Structure Ombrabulin
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
T12823 S516
化合物 T12823
1016543-77-3 98%
TargetMol Chemical Structure S516
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
TQ0202 Epothilone D
埃博霉素
189453-10-9 98%
TargetMol Chemical Structure Epothilone D
Epothilone D (KOS 862) is an effective microtubule stabilizer.
T16386 Ombrabulin hydrochloride
化合物 T16386
253426-24-3 98%
TargetMol Chemical Structure Ombrabulin hydrochloride
Ombrabulin hydrochloride 是一种合成的、具有选择性的 CA-4 磷酸酯或 Ombrabulin 的衍生物,能破坏内皮细胞的微管蛋白细胞骨架,具有抗血管作用。Ombrabulin 是是一种微管蛋白聚合抑制剂,是 combretastatin a -4化合物类的一员,是一种水溶性的微管蛋白解聚肿瘤血管...
T13225 Tubulin inhibitor 7
化合物 T13225
1309925-41-4 98%
TargetMol Chemical Structure Tubulin inhibitor 7
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
TQ0141 Taltobulin
他托布林
228266-40-8 98%
TargetMol Chemical Structure Taltobulin
Taltobulin (HTI-286) 是一种三肽半胱氨酸的合成类似物,是一种微管蛋白抑制剂,在体外抑制肝肿瘤细胞增殖和体内肿瘤生长。Taltobulin 具有细胞毒性,诱导有丝分裂停滞以及凋亡 (apoptosis),可用于研究乳腺癌和与微管组织相关的疾病。
OSIP-486823
T13807
OSIP-486823(CP248) 是一种新型有效的微管干扰剂,对蛋白激酶 G (PKG) 和微管均具有亲和力。
Combretastatin A-1
T36848
Combretastatin A-1 是一种有效的微管抑制剂,具有抗肿瘤和抗血管活性,通过微管蛋白解聚介导的 AKT 失活抑制 Wnt/β-catenin 通路发挥作用,可用于研究肝癌。
Tasidotin hydrochloride
T16997
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
Verubulin
T17229
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
Vinblastine
T6721
Vinblastine 抑制微管形成并抑制 nAChR 活性,IC50 为 8.9 μM,用于治疗某些类型的癌症。
Tubulysin A
TQ0112
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
Tubulin inhibitor 1
T13227
Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
AZ82
T10428
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
Jasplakinolide
T11712
Jasplakinolide(Jaspamide) 是一种来自海洋海绵 (marine sponge) 的天然环状肽,是一种有效的肌动蛋白聚合反应 (actin polymerization) 诱导剂。Jasplakinolide 具有抗真菌和抗肿瘤活性,可以稳定先前存在的肌动蛋白丝。Jasplakinolide 与鬼笔...
S-methyl DM1
T12805
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
Mivobulin
T12052
Mivobulin is an inhibitor of tubulin .
SS28
T13901
SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
Pironetin
T16543
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
Vinflunine Tartrate
T6722
Vinflunine Tartrate 是一种独特的新型长春花生物碱,具有抑制有丝分裂和微管蛋白相互作用活性的特性。
Ombrabulin
T16387
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
S516
T12823
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
Epothilone D
TQ0202
Epothilone D (KOS 862) is an effective microtubule stabilizer.
Ombrabulin hydrochloride
T16386
Ombrabulin hydrochloride 是一种合成的、具有选择性的 CA-4 磷酸酯或 Ombrabulin 的衍生物,能破坏内皮细胞的微管蛋白细胞骨架,具有抗血管作用。Ombrabulin 是是一种微管蛋白聚合抑制剂,是 combretastatin a -4化合物类的一员,是一种水溶性的微管蛋白解聚肿瘤血管...
Tubulin inhibitor 7
T13225
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
Taltobulin
TQ0141
Taltobulin (HTI-286) 是一种三肽半胱氨酸的合成类似物,是一种微管蛋白抑制剂,在体外抑制肝肿瘤细胞增殖和体内肿瘤生长。Taltobulin 具有细胞毒性,诱导有丝分裂停滞以及凋亡 (apoptosis),可用于研究乳腺癌和与微管组织相关的疾病。
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