Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.

Cat. No.	Product Name	CAS No.	Purity
T16997	Tasidotin hydrochloride 化合物 T16997	623174-20-9	98%
T16997	Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
T17229	Verubulin 化合物 T17229	827031-83-4	98%
T17229	Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
T6721	Vinblastine 长春质碱	865-21-4	98%
T6721	Vinblastine 抑制微管形成并抑制 nAChR 活性，IC50 为 8.9 μM，用于治疗某些类型的癌症。
TQ0112	Tubulysin A 化合物Tubulysin A	205304-86-5	98%
TQ0112	Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
T13807	OSIP-486823 化合物 T13807	200803-37-8	98%
T13807	OSIP-486823 is a microtubule-interfering agent with distinct biological effects on both protein kinase G (PKG) and microtubules.
T13227	Tubulin inhibitor 1 化合物 T13227	2237054-53-2	98%
T13227	Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
T10428	AZ82 化合物 T10428	1449578-65-7	98%
T10428	AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
T10704	CCB02 化合物CCB02	2100864-57-9	98%
T10704	CCB02 是选择性的 CPAP-tubulin 相互作用抑制剂。CCB02能够与 tubulin 结合，竞争 β-tubulin 的 CPAP 结合位点，IC50 值为 689 nM，显示出高效的抗肿瘤活性。CCB02 对其他的蛋白没有抑制作用，包括中心体、细胞周期相关蛋白，对 Aurora A，Plk1，Plk2，C...
T12805	S-methyl DM1 化合物 T12805	912569-84-7	98%
T12805	S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
T12052	Mivobulin 化合物 T12052	122332-18-7	98%
T12052	Mivobulin is an inhibitor of tubulin .
T13901	SS28 化合物 T13901	141172-08-9	98%
T13901	SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
T16543	Pironetin 化合物 T16543	151519-02-7	98%
T16543	Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
T6722	Vinflunine Tartrate 长春氟宁酒石酸盐	1201898-17-0	98%
T6722	Vinflunine Tartrate 是一种独特的新型长春花生物碱，具有抑制有丝分裂和微管蛋白相互作用活性的特性。
T16387	Ombrabulin 化合物 T16387	181816-48-8	98%
T16387	Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
T12823	S516 化合物 T12823	1016543-77-3	98%
T12823	S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
TQ0202	Epothilone D 埃博霉素	189453-10-9	98%
TQ0202	Epothilone D (KOS 862) is an effective microtubule stabilizer.
T16386	Ombrabulin hydrochloride 化合物 T16386	253426-24-3	98%
T16386	Ombrabulin hydrochloride 是一种合成的、具有选择性的 CA-4 磷酸酯或 Ombrabulin 的衍生物，能破坏内皮细胞的微管蛋白细胞骨架，具有抗血管作用。Ombrabulin 是是一种微管蛋白聚合抑制剂，是 combretastatin a -4化合物类的一员，是一种水溶性的微管蛋白解聚肿瘤血管...
T13225	Tubulin inhibitor 7 化合物 T13225	1309925-41-4	98%
T13225	Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
TQ0141	Taltobulin 化合物Taltobulin	228266-40-8	98%
TQ0141	Taltobulin (HTI-286) is a potent tubulin inhibitor.
T13228	Tubulysin D 微管蛋白抑制剂 D	309935-57-7	98%
T13228	Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.