w 13

W 13 is a biochemical.

W13 是 MsbA 的有效抑制剂，是 ATPase 刺激剂 (EC50: 5.5 μM)。

W-13 hydrochloride (W-13 HCl) 是一种钙调蛋白拮抗剂。

PROTAC tubulin-Degrader-1（化合物 W13）作为PROTAC tubulin的抑制剂，展示了对人类肺癌的抗肿瘤活性。

W000113414_I13是一种酸性神经酰胺酶 (AC) 抑制剂。W000113414_I13 对 AC 具有剂量依赖性抑制作用，IC50值为6.6 μM，可用于癌症研究。

Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) 是一种聚乙烯醇，分子量为 13000-23000，水解度为 87-89%。水解度表示原聚醋酸乙烯酯中醋酸基转为羟基的百分比。Polyvinyl alcohol 是通过乙烯醋酸酯聚合后除去醋酸基得来的。87-89% 的水解度意味着许多乙酸酯基团已经被转化，导致 PVA 结构中羟基增多。水解度不同的 Polyvinyl alcohol 可用于形成自交联冷冻凝胶，广泛用作生物辅料。

PVA (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization) 是一种可生物降解的聚合物，PVA (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization) 可以与多种生物聚合物和亲水性合成聚合物共混，以增强薄膜的机械性能。

Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) 是一种水溶性乙烯基聚合物，也称为PVA，具有非离子表面活性剂的性质。它可以作为可生物降解的聚合物，广泛应用于粘合剂、涂料、纺织品、陶瓷和化妆品等领域。

Vorinostat (SAHA) 是一种泛的组蛋白脱乙酰酶 (HDAC) 抑制剂 (IC50=10 nM)，对 HDAC1 2 3 6 7 11 均有抑制活性。 Vorinostat 具有抗肿瘤活性，可以诱导细胞分化，阻滞细胞周期，诱导细胞凋亡。

Niclosamide (Niclocide) 是一种口服生物可利用的氯化水杨酰苯胺。它通过抑制 DNA 复制，具有驱虫和潜在的抗肿瘤活性。

BW-1370U87 是一种可逆的竞争性单胺氧化酶-A抑制剂，可用于研究抑郁症和其他中枢神经系统疾病。

DW-1350 is an antagonist of LTB4 receptor.

SLW131 (Compound 10) 是一种CCR7的拮抗剂，展现出对CCR7的高亲和力，Ki为9.85 nM。SLW131 有效抑制CCL19诱导的Go蛋白活化，IC50为29.4 μM，并且抑制β-arrestin2的募集，IC50为6.0 μM。此外，SLW131还能抑制CCL19引发的原代BMDC细胞形态变化，以及CCR7介导的小鼠CD4+ T细胞的迁移。

Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.3,4 |1. Mallatou, H., Pappa, E., and Massouras, T. Changes in free fatty acids during ripening of Teleme cheese made with ewes', goats', cows' or a mixture of ewes' and goats' milk. Int. Dairy J. 13(1-3), 211-219 (2003).|2. Hyang, C.B., Alimova, Y., Myers, T.M., et al. Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. Arch. Oral Biol. 56(7), 650-654 (2011).|3. Onkenhout, W., Venizelos, V., van der Poel, P.F.H., et al. Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. Clin. Chem. 41(10), 1467-1474 (1995).|4. Rinaldo, P., O'Shea, J.J., Coates, P.M., et al. Medium-chain acyl-CoA dehydrogenase deficiency. Diagnosis by stable-isotope dilution measurement of urinary n-hexanoylglycine and 3-phenylpropionylglycine. N. Engl. J. Med. 319(20), 1308-1313 (1988).

Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2 1.Hadd, H.E., Slikker, W., Jr., and Helton, E.D.The synthesis and characterization of the glucopyranosiduronic acids of 17a-ethynylestradiol-17bJ. Steroid Biochem.13(9)1107-1114(1980) 2.Griffith, D.R., Soule, M.C.K., Eglinton, T.I., et al.Steroidal estrogen sources in a sewage-impacted coastal oceanEnviron. Sci.: Processes Impacts18(8)931-1106(2016)