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Anti-CCL28 Antibody (3W134)
还可以产品编号 TMAY-01034
别名 SCYA28, MEC, chemokine (C-C motif) ligand 28, CCK1
Anti-CCL28 Antibody (3W134) 是一种 Mouse 抗体，靶向 CCL28。Anti-CCL28 Antibody (3W134) 可用于 ELISA。
Anti-CCL28 Antibody (3W134)
Anti-CCL28 Antibody (3W134)
还可以产品编号 TMAY-01034 别名 SCYA28, MEC, chemokine (C-C motif) ligand 28, CCK1
Anti-CCL28 Antibody (3W134) 是一种 Mouse 抗体，靶向 CCL28。Anti-CCL28 Antibody (3W134) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 595 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CCL28 Antibody (3W134) is a Mouse antibody targeting CCL28. Anti-CCL28 Antibody (3W134) can be used in ELISA. |
| 别名 | SCYA28, MEC, chemokine (C-C motif) ligand 28, CCK1 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3W134 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCL28 / SCYA28 (rh CCL28 / SCYA28; TMPY-03728; NP_683513.1; Ile23-Tyr127). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues and secretions suggest that this protein plays an important role in innate immune protection of the epithelial surfaces. CCL28 is a human chemokine constitutively expressed by epithelial cells in diverse mucosal tissues and is known to attract a variety of immune cell types including T-cell subsets and eosinophils. Elevated levels of CCL28 have been found in the airways of individuals with asthma, and previous studies have indicated that CCL28 plays a vital role in the acute development of post-viral asthma. CCL28 presents a novel target for the development of alternative asthma therapeutics. The dental decay of children leads to the secretion of chemokine CCL28, which promotes the secretion of sIgA in saliva. CC chemokine ligand28 (CCL28) has been reported as a severity marker in atopic dermatitis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CCL28 / SCYA28 Protein (TMPY-03728) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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