在血液系统恶性肿瘤中,CD19、BCMA 和 CD22 是最常研究的靶点蛋白。其中CD19是治疗 B 细胞血液癌症的首要靶点。BCMA 和 CD22 都是 B 细胞表面表达的抗原,靶向这两个靶点的细胞疗法可以用于治疗对靶向 CD19 的细胞疗法产生耐药性的 B 细胞血液癌症患者。其他正在研究的相关靶点还有GPRC5D、CLEC12A和 CD7等。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00066 | BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
|
Human | Human Cells |
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consis... | |||
TMPJ-00097 | NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | Human Cells |
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil... | |||
TMPJ-00122 | NKG2D/CD314 Protein, Mouse, Recombinant (His)
NKG2D/CD314 Protein, Mouse, Recombinant (His)
|
Mouse | Human Cells |
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil... | |||
TMPJ-00148 | FOLR1 Protein, Rhesus macaque, Recombinant (His)
FOLR1 Protein, Rhesus macaque, Recombinant (His)
|
Rhesus Macaque | Human Cells |
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lu... | |||
TMPJ-00184 | CD20 Protein, Human, Recombinant (Flag)
CD20 Protein, Human, Recombinant (Flag)
|
Human | Human Cells |
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ... | |||
TMPJ-00185 | CD20 Protein, Human, Recombinant (His & Flag)
CD20 Protein, Human, Recombinant (His & Flag)
|
Human | Human Cells |
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ... | |||
TMPJ-00190 | CD38 Protein, Mouse, Recombinant (hFc)
CD38 Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It sy... | |||
TMPJ-00221 | SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, ... | |||
TMPJ-00222 | SLAMF7 Protein, Human, Recombinant (mFc)
SLAMF7 Protein, Human, Recombinant (mFc)
|
Human | Human Cells |
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, ... | |||
TMPJ-00329 | CD19 Protein, Rhesus macaque, Recombinant (hFc)
CD19 Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus macaque | Human Cells |
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B c... | |||
TMPJ-00340 | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
|
Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00341 | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
|
Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00342 | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
|
Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00343 | CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
|
Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00392 | Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ... | |||
TMPJ-00393 | Siglec-2/CD22 Protein, Human, Recombinant (hFc)
Siglec-2/CD22 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ... | |||
TMPJ-00444 | Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)
|
Mouse | Human Cells |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ... | |||
TMPJ-00487 | SDC1 Protein, Human, Recombinant (hFc)
SDC1 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cyt... | |||
TMPJ-00488 | SDC1 Protein, Human, Recombinant (His)
SDC1 Protein, Human, Recombinant (His)
|
Human | Human Cells |
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cyt... | |||
TMPJ-01434 | BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | Human Cells |
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one... |