utilization

1-Undecanol (1-Hendecanol) 是水果、黄油、鸡蛋和熟猪肉等许多食品中的天然产物，用作调味成分。它也可通过微生物从 2-tridecanol 中产生。

Clorsulon (L631529) 是一种具有口服活性的灭虫试剂，用于犊牛和羊的肝吸虫 感染。它也是 3-磷酸甘酸酯和 ATP 的竞争性抑制剂，可抑制成熟肝片吸虫对葡萄糖的利用以及乙酸和丙酸的形成。

D-mannoheptose is the main non-structural carbohydrate in avocado. D-mannoheptose is a specific inhibitor of D-glucose phosphorylation. D-mannoheptose can prevent the release of insulin and the utilization of carbohydrates in rats.

BM152054 是一种有效的 PPARγ配体，可以通过加强胰岛素作用来诱导外周组织对葡萄糖的利用。

CFTR校正剂8是一种对囊性纤维化跨膜传导调节器（CFTR）具有高效调控作用的化合物。该化合物特别用于与囊性纤维化相关的研究，这是一种主要影响肺和消化系统的遗传性疾病[1]。

Trimetazidine dihydrochloride (Vastarel F) 是细胞保护性抗缺血剂，也用作缺血性心脏病或心绞痛的血管扩张剂，具有抗氧化，抗炎，抗伤害和胃保护作用。它可通过抑制脂肪酸代谢提高心肌葡萄糖利用率。

L-(+)-Arabinose 能够选择性抑制肠道蔗糖酶，并抑制因蔗糖摄入而导致的血浆葡萄糖提高。

Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。

Azido-PEG8-NHS ester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl/ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].

RGH-5526是一种新型的抗高血压药。它引起下丘脑去甲肾上腺素（NA）周转（利用）增加，下丘脑去甲肾上腺素能神经元活性的增加可能导致外周交感神经活性的降低，从而显著降低血压。

m-PEG4-Boc is a cleavable 4-unit polyethylene glycol (PEG) linker, widely employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, m-PEG4-Boc serves as a PEG-based PROTAC linker, enabling its utilization in the synthesis of PROTACs [2].

Nutlin-C1-amido-PEG4-C2-N3 is a novel compound that functions as a ligand-linker conjugate for the E3 ligase. It is a synthesized molecule incorporating the MDM2 ligand derived from Nutlin 3, and a 4-unit PEG linker. This compound is specifically designed for utilization in PROTAC technology.

Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is an E3 ligase ligand-linker conjugate which is designed using Thalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is synthesized specifically for utilization in PROTAC technology.

ZLN005 (hydrochloride) 是一种激活过氧化物酶体增殖激活受体-g 辅激活因子-1α (PGC-1α) 的化合物。它能在骨骼肌细胞中促进 PGC-1α 及其下游基因的表达，提高葡萄糖利用率和脂肪酸氧化能力。在糖尿病 db/db 小鼠中，ZLN005 (hydrochloride) 增加了骨骼肌中 PGC-1α 及其下游基因的转录，加速脂肪氧化，并提高葡萄糖耐量、丙酮酸耐受性和胰岛素敏感性。

D-Thyroxine (Dextroxin) 是一种甲状腺激素，对 TSH 的分泌具有抑制作用，可用于研究高胆固醇血症。

Trimetazidine是一种无关血流动力学的抗心绞痛剂，能够选择性地抑制mitochondrial enzyme 3-ketoacyl coenzyme A thiolase（LC 3-KAT）从而防止游离脂肪酸的β-氧化，IC50 值为 75 nM。Trimetazidine通过改变心脏代谢防止缺血再灌注损伤，具有抗氧化和抗缺血伤害的作用。

CHIR-98014 (CT98014) 是有效的，细胞通透的GSK-3抑制剂，可抑制 GSK-3α (IC50:0.65 nM) 和 GSK-3β (IC50:0.58 nM) 的活性，对 cdc2 和 erk2 的作用较弱。

FK-614 is a selective agonist of peroxisome proliferator-activated receptor gamma. FK-614 improves peripheral glucose utilization while decreases hepatic insulin extraction in alloxan-induced diabetic dogs.

U-0521, an inhibitor of catechol-O-methyltransferase (COMT), enhances the availability and utilization of levodopa in the brain.

3-Iodothyronamine hydrochloride是一种速效和内源性的甲状腺激素衍生物，能够在体外激活TAAR1和在体内诱导体温降低，可用于研究内分泌与代谢。

yGsy2p-IN-H23 is a potent, first-in-class inhibitor specifically designed to target yeast glycogen synthase 2 (yGsy2p). It demonstrates an IC50 value of 875 μM for human glycogen synthase 1 (hGYS1). This compound binds precisely within the uridine diphosphate glucose (UDPG) binding pocket of yGsy2p. Its utilization in research primarily focuses on studying glycogen storage diseases (GSDs).

H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process.

Gliadin p31-43, an undigested peptide derived from gliadin, prompts an innate immune response in the intestine and disrupts endocytic trafficking. Moreover, its utilization in celiac disease research has proven beneficial.

7-Deaza-7-propargylamino-3'-azidomethyl-dATP, an analog of deoxyadenosine triphosphate (dATP), finds extensive utilization in next-generation sequencing (NGS).