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| Cat. No. | Product Name | ||
|---|---|---|---|
| L2550 | 谷氨酰胺代谢化合物库 | 580 compounds | |
| 580 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选； | |||
| Cat. No. | Product Name | Target | Signaling Pathways |
|---|---|---|---|
| TJO2729 |
L-Alanine
L-2-Aminopropionic acid,alanine,丙氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
| Alanine 是一种非必需氨基酸，可参与糖和酸的代谢，为肌肉组织、大脑和中枢神经系统提供能量，并增强免疫力。 | |||
| T7507 | γ-L-Glutamyl-L-alanine | Others; Endogenous Metabolite | Metabolism; Others |
| γ-L-Glutamyl-L-alanine 由γ-谷氨酸和丙氨酸组成，是CRF21（γ-谷氨酰环转移酶，GGCT）的底物。 | |||
| T13576 |
β-cyano-L-Alanine
Beta-cyano-l-alanine |
Others | Others |
| β-cyano-L-Alanine 是广泛存在于高等植物中的腈，氰基丙氨酸合成酶以氰化物和半胱氨酸作为底物反应产生。它消除了乙醇对脑缺血/再灌注 (I/R) 损伤的保护作用。 | |||
| T8054 |
L-Leucyl-L-alanine
Leucyl-alanine,L-亮氨酸-L-丙氨酸,L-Leucyl-L-alanine Hydrate |
Endogenous Metabolite; Others | Metabolism; Others |
| L-Leucyl-L-alanine Hydrate 是由 L-亮氨酸和 L-丙氨酸组成的简单二肽。 | |||
| T6987 |
β-Chloro-L-alanine
3-Chloro-L-alanine,L-β-Chloroalanine,3-氯-L-丙氨酸 |
Antibacterial | Microbiology/Virology |
| 3-Chloro-L-alanine 是一种抑菌氨基酸类似物，可抑制多种酶，包括苏氨酸脱氨酶和丙氨酸消旋酶。 | |||
| T22911 |
β-N-methylamino-L-alanine hydrochloride
L-BMAA hydrochloride |
Others | Others |
| L-BMAA hydrochloride 是由蓝细菌产生的一种神经毒素，既有导致肌萎缩性侧索硬化症 (ALS) 以及其他可能的神经退行性疾病可能性。 | |||
| T37216 | N-Arachidonoyl-L-Alanine | ||
| Several different arachidonoyl amino acids, including N-arachidonoyl-L-alanine (NALA), have been isolated and characterized from bovine brain. The glycine congener (NAGly) was further characterized and found to suppress formalin-induced pain in rats. NALA may have activity at cannabinoid receptor and/or VR1, but has not been fully characterized to date. | |||
| T66030 | ((Benzyloxy)carbonyl)-L-alanine | ||
| T67574 | 3-Chloro-L-alanine Hydrochloride | ||
| T65194 | Fmoc-L-(4-thiazolyl)-Alanine | ||
| T66795 | Boc-L-Alanine benzyl ester | ||
| T66031 | L-Alanine methyl ester hydrochloride | ||
| T7507L | γ-L-Glutamyl-L-alanine acetate (5875-41-2 Free base) | ||
| T77219 | N-((Allyloxy)carbonyl)-N-methyl-L-alanine | ||
| N-((Allyloxy)carbonyl)-N-methyl-L-alanine 是一种丙氨酸衍生物。N-((Allyloxy)carbonyl)-N-methyl-L-alanine 可用于合成补体因子 D (complementfactor D) 抑制剂。补体因子 D 抑制剂可用于免疫系统相关疾病的研究。 | |||
| T31193 |
D-Alanyl-L-alanine
NSC 203792,N-D-Alanyl-L-alanine,L-Alanine, D-alanyl-,NSC-203792,D-Alanylalanine |
||
| D-Alanyl-L-alanine is a bioactive chemical. | |||
| T65104 | N-[(S)-1-Carbethoxy-1-butyl]-L-alanine | ||
| T17468 | Azide-PEG3-L-alanine-Fmoc | Others | Others |
| Azide-PEG3-L-alanine-Fmoc is a polyethylene glycol (PEG)-based linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1]. | |||
| T4839 |
Ac-Ala-OH
N-乙酰-L-丙氨酸,N-Acetyl-L-alanine |
Others; Endogenous Metabolite | Metabolism; Others |
| N-Acetyl-L-alanine 是内源性代谢产物的一种。 | |||
| T5083 |
L-Cysteic acid monohydrate
3-Sulfo-L-alanine Monohydrate,L-磺基丙氨酸 一水合物 |
Endogenous Metabolite; GluR | Metabolism; Neuroscience |
| L-Cysteic acid monohydrate 是内源性代谢产物的一种。 | |||
| T5764 |
Alliin
(S)-3-(Allylsulphinyl)-L-alanine,蒜氨酸 |
PPAR; NF-κB | DNA Damage/DNA Repair; Metabolism; NF-κB |
| Alliin 是一种从大蒜中提取的亚砜化合物，具有口服活性，表现出降血糖、抗氧化和抗炎特性。 | |||
| T2A2532 |
L-Histidine
组氨酸,L-组氨酸,L-(-)-Histidine,Glyoxaline-5-alanine,L-Hisidine,histidine |
Endogenous Metabolite; Mitochondrial Metabolism | Metabolism |
| Histidine 是人类生长和组织修复所需的一种半必需氨基酸（儿童应从食物中获得）。Histidine 是线粒体谷氨酰胺转运的抑制剂。 | |||
| T4934 |
1-Methyl-L-histidine
1-甲基-L-组氨酸,Nτ-Methyl-L-histidine,3-(1-Methylimidazol-4-yl)-L-alanine |
Endogenous Metabolite | Metabolism |
| 1-Methyl-L-histidine，一种人内源性代谢物，是肉类和外源性 3-methylhistidine 摄入的客观生物标记。 | |||
| T19350 |
H-Val-Ala-OH
缬氨酰-丙氨酸,Valyl-alanine |
Endogenous Metabolite | Metabolism |
| H-Val-Ala-OH 是由 L-缬氨酸和 L-丙氨酸残基形成的二肽，具有代谢作用。 | |||
| T40840 |
H-Tyr-Ala-OH
H-Tyr-Ala-OH,Tyrosylalanine |
Others | Others |
| H-Tyr-Ala-OH 是一种L-酪氨酸和L-丙氨酸组成的二肽。 | |||
| T41032 | Lysostaphin | Antibacterial | Microbiology/Virology |
| Lysostaphin is a potent antistaphylococcal compound that exhibits enzymatic activity through three distinct enzymes: glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase, and N-acetyl muramyl-L-alanine amidase. | |||
| TN1003 |
DL-Alanine
DL-2-Aminopropionic acid |
Endogenous Metabolite | Metabolism |
| DL-Alanine 是一种氨基酸，是L-和D-丙氨酸的外消旋化合物。DL-Alanine 与硝酸银水溶液一起用于纳米颗粒生成时常作为还原剂和封端剂。DL-Alanine 是一种甜味剂，可把它位与甘氨酸和糖精钠归为一类。DL-Alanine 在组织和肝脏之间的葡萄糖-丙氨酸循环中起重要作用。DL-Alanine 可用于研究 Cu、Zn、Cd 等过渡金属螯合。 | |||
| T5593 |
L-Alanyl-L-glutamine
L-丙氨酸-L-谷氨酰胺,L-丙氨酰-L-谷氨酰胺,Ala-Gln |
Endogenous Metabolite; Others | Metabolism; Others |
| Ala-Gln 是一种由丙氨酸和谷氨酰胺组成的二肽，对抗氧化系统有益，能够减轻炎症，并能够在分解代谢情况下调节热休克蛋白 (HSP) 的反应。 | |||
| T1689 |
Enalapril IMpurity B
依那普利杂质B,(+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine |
Others | Others |
| Enalapril IMpurity 是 Moexipril 中间体，是 Imidapril 的主要代谢物。 | |||
| T5978 |
2,3-Diaminopropionic acid hydrochloride
L-2,3-二氨基丙酸盐酸盐,3-Amino-L-alanine hydrochloride |
Others | Others |
| 2,3-Diaminopropionic acid hydrochloride 是一种竞争性的胱甘肽酶抑制剂。 | |||
| T6569 |
Mimosine
NSC 69188,Leucenol,Leucenine,L-Mimosine,含羞草素 |
Others | Others |
| Mimosine 是一种酪氨酸类似物，具有抗癌和抗炎等活性。它可通过其强大的铁结合活性作为抗氧化剂，是一种 Fe(III) 螯合剂。它作用于人类白血病细胞，通过金属离子螯合、线粒体激活和诱导活性氧产生来诱导细胞凋亡。 | |||
| T4707 |
3-Hydroxyanthranilic acid
3-羟基-2-氨基苯甲酸,3-HYDROXY-2-AMINOBENZOIC ACID |
Others; Endogenous Metabolite | Metabolism; Others |
| 3-Hydroxyanthranilic acid 是犬尿氨酸途径中的色氨酸代谢物。它已在人类表皮和膀胱组织中发现，并且在多种生物体液中也已检测到，例如尿液和血液。在细胞内，它主要位于细胞质中。 它存在于从酵母到人类的所有真核生物中。 | |||
| T5799 | Arecaidine hydrochloride | Others | Others |
| Arecaidine hydrochloride 是一种具有高效 GABA 吸收抑制功能的吡啶生物碱。它是 H+偶联的氨基酸转运蛋白 1 (PAT1，SLC36A1) 的底物，能够竞争性抑制 L-脯氨酸的摄取。 | |||
| T3377 |
L-Phenylalanine
L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine |
Calcium Channel; iGluR; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
| phenylalanine 是分离自大肠杆菌的必需氨基酸，是 NMDARs(KB573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂，用于食品香料和药品的生产中。它是一种电压依赖性 α2δ 亚基 Ca2+通道拮抗剂，Ki 为 980 nM。 | |||
| T33866 |
Palmitoyl alanine
N-Palmitoyl-L-alanine,Palmityl-L-alanine,Codeage PA |
||
| Palmitoyl alanine is a fatty acid. | |||
| T34103 |
Polyalanine
Poly-L-alanine,Poly-DL-alanine |
||
| Polyalanine is a bioactive chemical. | |||
| T34947 |
Trimethylalanine
L-Alanine betaine,Alaninebetaine,alpha-Alanine betaine |
||
| Trimethylalanine is an aminoacid. | |||
| T20161 |
Lauroyl alanine
Aminiosurfact LA,Lauroylalanine,N-Lauroyl-L-alanine |
||
| Lauroyl alanine is a fatty acid amide. It may be used to support the physical gelation of binary mixtures of aliphatic and aromatic hydrocarbon solvents. | |||
| T39830 |
L-AP3
3-Phosphono-L-alanine,L-AP3 |
||
| L-AP3 is a potent antagonist of metabotropic glutamate receptor (mGluR), demonstrating inhibitory effects on D-phosphoserine and L-phosphoserine with IC50 values of 368 μM and 2087 μM, respectively. | |||
| T33073 |
Lysinoalanine, (S,S)-
N6-Lysino-L-alanine |
||
| Lysinoalanine, (S, S)- is a toxic compound from processed proteinaceous foods. | |||
| T31159 |
Cysteinesulfenic acid
L-Cysteinesulfenic acid,S-(Propylcarbamoyl)cysteine,L-Cysteine sulfoxide,L-Alanine, 3-sulfeno- |
||
| Cysteinesulfenic acid is a protein-sulfenic acid involved in enzyme catalysis, redox regulation, and signal transduction. | |||
| T19848 |
Cyclosporin B
Antibiotic S 7481F2,7-L-Alanine-cyclosporin A |
||
| Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also | |||
| T20264 |
Ala-Glu-OH
Alanylglutamic acid,Alanine glutamate,L-Glutamic acid, N-L-alanyl- |
||
| Alanine glutamate is an agent of the dipeptide. | |||
| T20162 |
Sodium N-lauroylalanine
N-Lauroyl-L-alanine sodium salt |
||
| Sodium N-lauroylalanine is an agent of fatty acid. | |||
| T23700 |
Alalevonadifloxacin HCl
Alalevonadifloxacin hydrochloride |
||
| Alalevonadifloxacin HCl is a novel l-alanine ester prodrug of levonadifloxacin. | |||
| T38707 | MPC-0767 | ||
| MPC-0767 is a potent, selective, and orally active hsp90 inhibitor. MPC-0767 is an L-alanine ester prodrug of MPC-3100 with improved chemical stability. | |||
| TMPY-03754 | SCLY Protein, Human, Recombinant (His Tag) | ||
| SCLY, also known as selenocysteine lyase, belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. It is a novel enzyme that exclusively decomposes L-selenocysteine into L-alanine and H2Se in various mammalian tissues. SCLY contains pyridoxal 5'-phosphate and weighs approximately 85,000. SCLY participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate. Its maximum reactivity is at about pH 9.0. It was shown that 1 mol of selenocysteine is conver... | |||
| T37070 | Pyridomycin | ||
| Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 μg/ml). | |||
| TMPY-01099 | GPT Protein, Rat, Recombinant (His Tag) | ||
| Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc... | |||
| TMPY-01100 | GPT2 Protein, Rat, Recombinant (His Tag) | ||
| Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share ... | |||
| T70990 | ADMA-d6 | ||
| NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da... | |||
| Cat. No. | Product Name | Target | Signaling Pathways |
|---|---|---|---|
| TJO2729 |
L-Alanine
L-2-Aminopropionic acid,alanine,丙氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
| Alanine 是一种非必需氨基酸，可参与糖和酸的代谢，为肌肉组织、大脑和中枢神经系统提供能量，并增强免疫力。 | |||
| T13576 |
β-cyano-L-Alanine
Beta-cyano-l-alanine |
Others | Others |
| β-cyano-L-Alanine 是广泛存在于高等植物中的腈，氰基丙氨酸合成酶以氰化物和半胱氨酸作为底物反应产生。它消除了乙醇对脑缺血/再灌注 (I/R) 损伤的保护作用。 | |||
| T4839 |
Ac-Ala-OH
N-乙酰-L-丙氨酸,N-Acetyl-L-alanine |
Others; Endogenous Metabolite | Metabolism; Others |
| N-Acetyl-L-alanine 是内源性代谢产物的一种。 | |||
| T5083 |
L-Cysteic acid monohydrate
3-Sulfo-L-alanine Monohydrate,L-磺基丙氨酸 一水合物 |
Endogenous Metabolite; GluR | Metabolism; Neuroscience |
| L-Cysteic acid monohydrate 是内源性代谢产物的一种。 | |||
| T5764 |
Alliin
(S)-3-(Allylsulphinyl)-L-alanine,蒜氨酸 |
PPAR; NF-κB | DNA Damage/DNA Repair; Metabolism; NF-κB |
| Alliin 是一种从大蒜中提取的亚砜化合物，具有口服活性，表现出降血糖、抗氧化和抗炎特性。 | |||
| T2A2532 |
L-Histidine
组氨酸,L-组氨酸,L-(-)-Histidine,Glyoxaline-5-alanine,L-Hisidine,histidine |
Endogenous Metabolite; Mitochondrial Metabolism | Metabolism |
| Histidine 是人类生长和组织修复所需的一种半必需氨基酸（儿童应从食物中获得）。Histidine 是线粒体谷氨酰胺转运的抑制剂。 | |||
| T4934 |
1-Methyl-L-histidine
1-甲基-L-组氨酸,Nτ-Methyl-L-histidine,3-(1-Methylimidazol-4-yl)-L-alanine |
Endogenous Metabolite | Metabolism |
| 1-Methyl-L-histidine，一种人内源性代谢物，是肉类和外源性 3-methylhistidine 摄入的客观生物标记。 | |||
| T6569 |
Mimosine
NSC 69188,Leucenol,Leucenine,L-Mimosine,含羞草素 |
Others | Others |
| Mimosine 是一种酪氨酸类似物，具有抗癌和抗炎等活性。它可通过其强大的铁结合活性作为抗氧化剂，是一种 Fe(III) 螯合剂。它作用于人类白血病细胞，通过金属离子螯合、线粒体激活和诱导活性氧产生来诱导细胞凋亡。 | |||
| T4707 |
3-Hydroxyanthranilic acid
3-羟基-2-氨基苯甲酸,3-HYDROXY-2-AMINOBENZOIC ACID |
Others; Endogenous Metabolite | Metabolism; Others |
| 3-Hydroxyanthranilic acid 是犬尿氨酸途径中的色氨酸代谢物。它已在人类表皮和膀胱组织中发现，并且在多种生物体液中也已检测到，例如尿液和血液。在细胞内，它主要位于细胞质中。 它存在于从酵母到人类的所有真核生物中。 | |||
| T3377 |
L-Phenylalanine
L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine |
Calcium Channel; iGluR; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
| phenylalanine 是分离自大肠杆菌的必需氨基酸，是 NMDARs(KB573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂，用于食品香料和药品的生产中。它是一种电压依赖性 α2δ 亚基 Ca2+通道拮抗剂，Ki 为 980 nM。 | |||
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