在实体肿瘤方面CAR-T取得了一定的研究进展,包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比,实体瘤类型繁多、致病机制多样,靶标选择难度大,在研项目的靶点较为分散。整体来看,Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2(CLDN18.2)等是常见靶点。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00075 | CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
|
Mouse | Human Cells |
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular ... | |||
TMPJ-00097 | NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | Human Cells |
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil... | |||
TMPJ-00122 | NKG2D/CD314 Protein, Mouse, Recombinant (His)
NKG2D/CD314 Protein, Mouse, Recombinant (His)
|
Mouse | Human Cells |
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil... | |||
TMPJ-00148 | FOLR1 Protein, Rhesus macaque, Recombinant (His)
FOLR1 Protein, Rhesus macaque, Recombinant (His)
|
Rhesus Macaque | Human Cells |
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lu... | |||
TMPJ-00155 | Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated
Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated
|
Human | Human Cells |
Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective m... | |||
TMPJ-00200 | EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)
EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the ... | |||
TMPJ-00204 | TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated
TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | Human Cells |
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was origina... | |||
TMPJ-00205 | TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)
TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)
|
Human | Human Cells |
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was origina... | |||
TMPJ-00206 | TROP-2 Protein, Human, Recombinant (aa 27-274, hFc)
TROP-2 Protein, Human, Recombinant (aa 27-274, hFc)
|
Human | Human Cells |
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was origina... | |||
TMPJ-00308 | Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)
|
Cynomolgus | Human Cells |
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an... | |||
TMPJ-00309 | Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)
|
Cynomolgus | Human Cells |
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an... | |||
TMPJ-00310 | Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated
Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an... | |||
TMPJ-00311 | Nectin-4 Protein, Human, Recombinant (aa 32-351, hFc)
Nectin-4 Protein, Human, Recombinant (aa 32-351, hFc)
|
Human | Human Cells |
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an... | |||
TMPJ-00312 | Nectin-4 Protein, Human, Recombinant (mFc)
Nectin-4 Protein, Human, Recombinant (mFc)
|
Human | Human Cells |
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an... | |||
TMPJ-00337 | GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated
GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate... | |||
TMPJ-00414 | VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated
|
Human | Human Cells |
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in ... | |||
TMPJ-00415 | HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated
HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated
|
Human | Human Cells |
Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development... | |||
TMPJ-00593 | VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)
|
Human | Human Cells |
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in ... | |||
TMPJ-00646 | EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human... | |||
TMPJ-00647 | EGFR vIII Protein, Human, Recombinant (hFc)
EGFR vIII Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human... |