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Search Results for "dpph"
Targets Recommended: Others

99

抑制剂 & 化合物

69

天然产物

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Cat. No. Product Name Target Signaling Pathways
T11093 DPPH

2,2-联苯基-1-苦基肼基,2,2-Diphenyl-1-picrylhydrazyl

Others Others
DPPH 是一种稳定的自由基,可用于测量抗氧化剂的自由基清除活性。DPPH 中氮原子的奇数电子通过从抗氧化剂吸收氢原子而还原为相应的肼。通过 DPPH 方法可用于水性和非极性有机溶剂中,检查亲水性和亲脂性抗氧化剂。
TN2151 Rhamnocitrin

Others Others
Rhamnocitrin 是一种分离自黄芪(沙源子)中的类黄酮,具有抗氧化,抗炎和抗动脉粥样硬化活性。它是 DPPH 的清除剂(IC50:28.38 mM)。
T0611 Vanillylmandelic acid

3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid

Others Others
4-Hydroxy-3-methoxymandelic acid 是肾上腺素和去甲肾上腺素代谢的最终产物。它具有抗氧化活性,可以清除 DPPH 自由基(IC50:33 μM)。它也是神经递质代谢紊乱的标志物。
T5728 OsMundacetone

4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Reactive Oxygen Species; Apoptosis Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
Osmundacetone 是从白桦茸中分离出的一种天然产物,具有抗凋亡作用。它具有DPPH 清除活性,保护神经细胞免受氧化应激,可研究神经退行性疾病。
T3S1068 Oxyresveratrol

Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇

Tyrosinase; Autophagy; HSV Autophagy; Microbiology/Virology; Proteases/Proteasome
Oxyresveratrol 是非竞争性酪氨酸酶抑制剂,对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1,HSV-2和水痘带状疱疹病毒,具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T9135 Epirosmanol

Others Others
Epirosmanol 属于一类称为二萜内酯的有机化合物。这些是含有内酯部分的二萜类化合物。 Epirosmanol 是一种极弱碱性(基本中性)的化合物(基于其 pKa)。
T63750 α-Amylase-IN-1

Antioxidant Metabolism; oxidation-reduction
α-Amylase-IN-1 是一种 α-Amylase 抑制剂( IC50: 0.5509 μM)。α-Amylase-IN-1 具有抗氧化 (antioxidant) 活性,清除 DPPH 自由基的 IC50 值为 53.49 μM,可用于研究糖尿病和氧化应激相关疾病。
TN1601 Effusol

灯心草菲酚,厄弗酚

Caspase Apoptosis; Proteases/Proteasome
Effusol 是一种从 Juncus effuses 中分离到的酚类物质,对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP,保护海马功能对抗应激诱导的认知能力下降。
TN1788 Isookanin

HSV; Others Microbiology/Virology; Others
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。
TN1137 Isobutylshikonin

Others Others
Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。
TN2008 Okanin

TLR; NF-κB Immunology/Inflammation; NF-κB
Okanin 是鬼针草中的一种有效成分,可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。
T2S1086 Nepitrin

Nepetin-7-glucoside,假荆芥属苷

Antioxidant oxidation-reduction
Nepitrin 分离自Scrophularia striata 中,具有强大的抗炎、抗关节炎作用。
TN6489 Regaloside A

Others Others
 Regaloside A 是一种从百合中提取出的苯丙烷,在 160 ppm 时显示出 DPPH 自由基清除活性。Regaloside A 具有抗炎活性和抗抑郁活性。
T2936 Antiarol

3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚

Others Others
3,4,5-Trimethoxyphenol 是一种提取自 Salmaliamalabaricum 中的天然化合物。
T39887 (S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸

Others Others
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid 是分离自间肠隐球菌培养基的代谢物,具有高的 DPPH 清除自由基活性和抗氧化活性。
T3852 Rhodiosin

AChE; Antioxidant Neuroscience; oxidation-reduction
Rhodiosin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50=27.7 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。
TN2011 Ombuoside

Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷

Antibacterial Microbiology/Virology
Ombuoside 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。
TN3972 Epimedokoreanin B

Apoptosis; Others; Antibacterial Apoptosis; Microbiology/Virology; Others
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。
TN3466 Atherosperminine

cAMP; Calcium Channel; Parasite; AChR GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
Atherosperminine 是一种天然生物碱,在体外表现出抗疟原虫活性,IC50为 5.80 μM。它具有DPPH 自由基清除活性,其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂,具有螯合金属的能力。
TN2211 Silybin B

Silibinin B

Bcr-Abl; Beta Amyloid; Apoptosis Angiogenesis; Apoptosis; Cytoskeletal Signaling; Neuroscience; Tyrosine Kinase/Adaptors
Silybin B 是雷洛昔芬4′-和6-葡萄糖醛酸化的有效抑制剂,是水飞蓟素有效的抗纤维原性和抗低聚物成分,具有清除1,1-二苯基-2-吡啶酰肼(DPPH)自由基的活性 ,可通过减轻 DNA 损伤和细胞凋亡对顺铂诱导的神经毒性具有保护作用。Silybin B 对人慢性髓系白血病 K562细胞的生长抑制和诱导凋亡有较强的作用,是减轻顺铂所致的脑神经损伤的候选化合物。
T8168 Hydroxytyrosol Acetate

3,4-二羟基苯乙醇醋酸,HTy-Ac

Antioxidant oxidation-reduction
Hydroxytyrosol acetate 是从橄榄油中发现的,具有抗氧化作用。它清除 DPPH 自由基的活性比 hydroxytyrosol 弱。
T5S0089 Kaempferol-3-O-glucorhamnoside

Kaempferol 3-glucorhamnoside,百蕊草素I

Antioxidant; p38 MAPK; NF-κB MAPK; NF-κB; oxidation-reduction
Kaempferol-3-O-glucorhamnoside 是来源于百蕊草的一种类黄酮,在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T5S0281 Tubuloside A

NOS Immunology/Inflammation
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。
T3S0006 (E)-Ferulic acid methyl ester

(E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate

NO Synthase; JNK; TNF; Antifection; p38 MAPK; IL Receptor; COX Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience
Methyl (E)-ferulate 具有较强 DPPH 和 ABTS+自由基清除特性。
TN1011 Rhodionin

P450; AChE Metabolism; Neuroscience
Rhodionin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50为 19.49 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。
T3388 Calycosin-7-O-β-D-glucoside

Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷

Reactive Oxygen Species; MMP Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
Calycosin-7-O-beta-D-glucoside 是一种异黄酮,从黄芪中分离得到。它具有多种生物活性,包括心脏保护、神经保护、抗炎和抗氧化作用。
T3899 Calceolarioside B

木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A

Aromatase Endocrinology/Hormones
Calceolarioside B 是一种分离自Stauntonia hexaphylla 叶片中的天然产物。它抑制 DPPH 自由基清除活性(IC50:94.60 μM)。它显著抑制大鼠晶状体醛糖还原酶(RLAR)活性(C50:23.99 μM。
T13350 Wushanicaritin

Others Others
Wushanicaritin 在 DPPH 自由基清除活性测试中显示出显著的抗氧化活性 ,其IC50值为35.3 μM,具有抗肿瘤作用和抗炎活性。
T8895 Altenusin

FXR Metabolism
Altenusin 是天然的非甾体真菌代谢物,是新型 FXR 选择性激动剂,EC50 值为 3.2 ± 0.2 μM。它具有明显的 DPPH 自由基清除活性。
T37710 5-Hydroxyoxindole

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
5-Hydroxyoxindole 是尿酸的一种结构类似物,具有脂质过氧化抑制活性和自由基 DPPH 清除活性,可用于氧化应激介导的疾病的研究。
T3676 Sesamol

3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Sesamol 是芝麻油的主要成分,具有抗氧化和抗肿瘤活性。它是一种自由基清除剂,在 DPPH 实验中,IC50为 5.95±0.56 μg/mL。
TN4469 Lyoniresinol

Lyoniresinol 是一种从 Tarenna attenuata 分离出来的木质素,具有清除自由基的活性(IC50为82.4μM)和 DPPH 的抗氧化活性,显示出抗黑色素生成活性。Lyoniresinol 有强烈的苦味,而其对映体(-)-Lyoniresinol 是无味的。
TN4754 Persicoside

Others Others
Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN3193 6-O-Vanilloylajugol

Others Others
6-O-Vanilloylajugol demonstrates scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN1207 2,4,7-Trihydroxy-9,10-dihydrophenanthrene

Others Others
2,4,7-Trihydroxy-9,10-dihydrophenanthrene showS the DPPH free radical scavenging activity with EC(50) from 8.8 to 55.9 microM.
T13598 Caulophylline B

Others Others
Caulophylline B, an alkaloid extracted from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical.
T75477 Epicoccone B

Epicoccone B 首次报道于C.globosum,具有清除 DPPH 自由基的能力,IC50值为10.8 μM,并具有有效的 α-葡萄糖苷酶抑制作用,IC50值为 27.3 μM。具有抗HIV 活性。
TN1734 Heveaflavone

橡胶树双黄酮

Antioxidant; Topoisomerase DNA Damage/DNA Repair; oxidation-reduction
Heveaflavone 抑制拓扑异构酶 I 并清除 DPPH 自由基,具有抗增殖和抗氧化作用。
TN3292 8-Prenyldaidzein

Others Others
8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging.
TN4000 Erythristemine

Others Others
(+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical.
TN2545 1-Hydroxypinoresinol 1-O-glucoside

ROS Immunology/Inflammation
(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively.
TMA0245 Hexacosyl (E)-ferulate

Others Others
Hexacosyl (E)-ferulate displays significant antioxidant activity in the DPPH assay (RC50 = 0.0976 mg/mL). It also might be a chemotaxonomic marker in the genus Echinops.
TN6414 Plantanone B

Plantanone C exhibited moderate antioxidant activity against DPPH radical scavenging activity,with an IC50 value of 240. 2 μmol·L~(-1).
TN3061 4'-O-Methyllicoflavanone

Antioxidant oxidation-reduction
4'-O-Methyllicoflavanone 是从 Erythrina orientalis 的茎皮中分离得到的,对 DPPH 自由基具有抗氧化活性,IC50 值为 648.1 μM。
TN3879 Docosyl caffeate

Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL.
TN1876 Lobetyolinin

党参炔苷宁

Others Others
Lobetyolinin exhibits DPPH radical scavenging activity.
TN4708 Olivil

Others Others
(-)-Olivil displays a higher antioxidative effect against the free radical DPPH.
TN5052 Ssioriside

Others Others
Ssioriside shows moderate antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.
TN4865 Putraflavone

Beta Amyloid; BACE Neuroscience
Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.
TN4617 N-trans-Feruloyl-3-methoxytyramine

Others Others
N-trans-Feruloyl-3-methoxytyramine shows significantly DPPH radical scavenging activities.

化合物

DPPH
T11093
synonym: 2,2-联苯基-1-苦基肼基,2,2-Diphenyl-1-picrylhydrazyl
Target: Others
Rhamnocitrin
TN2151
synonym:
Target: Others
Vanillylmandelic acid
T0611
synonym: 3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid
Target: Others
OsMundacetone
T5728
synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one
Target: Reactive Oxygen Species, Apoptosis
Oxyresveratrol
T3S1068
synonym: Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇
Target: Tyrosinase, Autophagy, HSV
Epirosmanol
T9135
synonym:
Target: Others
α-Amylase-IN-1
T63750
synonym:
Target: Antioxidant
Effusol
TN1601
synonym: 灯心草菲酚,厄弗酚
Target: Caspase
Isookanin
TN1788
synonym:
Target: HSV, Others
Isobutylshikonin
TN1137
synonym:
Target: Others
Okanin
TN2008
synonym:
Target: TLR, NF-κB
Nepitrin
T2S1086
synonym: Nepetin-7-glucoside,假荆芥属苷
Target: Antioxidant
Regaloside A
TN6489
synonym:
Target: Others
Antiarol
T2936
synonym: 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚
Target: Others
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid
T39887
synonym: (S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸
Target: Others
Rhodiosin
T3852
synonym:
Target: AChE, Antioxidant
Ombuoside
TN2011
synonym: Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷
Target: Antibacterial
Epimedokoreanin B
TN3972
synonym:
Target: Apoptosis, Others, Antibacterial
Atherosperminine
TN3466
synonym:
Target: cAMP, Calcium Channel, Parasite, AChR
Silybin B
TN2211
synonym: Silibinin B
Target: Bcr-Abl, Beta Amyloid, Apoptosis
Hydroxytyrosol Acetate
T8168
synonym: 3,4-二羟基苯乙醇醋酸,HTy-Ac
Target: Antioxidant
Kaempferol-3-O-glucorhamnoside
T5S0089
synonym: Kaempferol 3-glucorhamnoside,百蕊草素I
Target: Antioxidant, p38 MAPK, NF-κB
Tubuloside A
T5S0281
synonym:
Target: NOS
(E)-Ferulic acid methyl ester
T3S0006
synonym: (E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate
Target: NO Synthase, JNK, TNF, Antifection, p38 MAPK, IL Receptor, COX
Rhodionin
TN1011
synonym:
Target: P450, AChE
Calycosin-7-O-β-D-glucoside
T3388
synonym: Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷
Target: Reactive Oxygen Species, MMP
Calceolarioside B
T3899
synonym: 木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A
Target: Aromatase
Wushanicaritin
T13350
synonym:
Target: Others
Altenusin
T8895
synonym:
Target: FXR
5-Hydroxyoxindole
T37710
synonym:
Target: Reactive Oxygen Species
Sesamol
T3676
synonym: 3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚
Target: Apoptosis, AMPK
Lyoniresinol
TN4469
synonym:
Target:
Persicoside
TN4754
synonym:
Target: Others
6-O-Vanilloylajugol
TN3193
synonym:
Target: Others
2,4,7-Trihydroxy-9,10-dihydrophenanthrene
TN1207
synonym:
Target: Others
Caulophylline B
T13598
synonym:
Target: Others
Epicoccone B
T75477
synonym:
Target:
Heveaflavone
TN1734
synonym: 橡胶树双黄酮
Target: Antioxidant, Topoisomerase
8-Prenyldaidzein
TN3292
synonym:
Target: Others
Erythristemine
TN4000
synonym:
Target: Others
1-Hydroxypinoresinol 1-O-glucoside
TN2545
synonym:
Target: ROS
Hexacosyl (E)-ferulate
TMA0245
synonym:
Target: Others
Plantanone B
TN6414
synonym:
Target:
4'-O-Methyllicoflavanone
TN3061
synonym:
Target: Antioxidant
Docosyl caffeate
TN3879
synonym:
Target:
Lobetyolinin
TN1876
synonym: 党参炔苷宁
Target: Others
Olivil
TN4708
synonym:
Target: Others
Ssioriside
TN5052
synonym:
Target: Others
Putraflavone
TN4865
synonym:
Target: Beta Amyloid, BACE
N-trans-Feruloyl-3-methoxytyramine
TN4617
synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN2151 Rhamnocitrin

Others Others
Rhamnocitrin 是一种分离自黄芪(沙源子)中的类黄酮,具有抗氧化,抗炎和抗动脉粥样硬化活性。它是 DPPH 的清除剂(IC50:28.38 mM)。
T0611 Vanillylmandelic acid

3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid

Others Others
4-Hydroxy-3-methoxymandelic acid 是肾上腺素和去甲肾上腺素代谢的最终产物。它具有抗氧化活性,可以清除 DPPH 自由基(IC50:33 μM)。它也是神经递质代谢紊乱的标志物。
T3S1068 Oxyresveratrol

Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇

Tyrosinase; Autophagy; HSV Autophagy; Microbiology/Virology; Proteases/Proteasome
Oxyresveratrol 是非竞争性酪氨酸酶抑制剂,对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1,HSV-2和水痘带状疱疹病毒,具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
TN1601 Effusol

灯心草菲酚,厄弗酚

Caspase Apoptosis; Proteases/Proteasome
Effusol 是一种从 Juncus effuses 中分离到的酚类物质,对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP,保护海马功能对抗应激诱导的认知能力下降。
TN1788 Isookanin

HSV; Others Microbiology/Virology; Others
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。
TN1137 Isobutylshikonin

Others Others
Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。
TN2008 Okanin

TLR; NF-κB Immunology/Inflammation; NF-κB
Okanin 是鬼针草中的一种有效成分,可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。
T2S1086 Nepitrin

Nepetin-7-glucoside,假荆芥属苷

Antioxidant oxidation-reduction
Nepitrin 分离自Scrophularia striata 中,具有强大的抗炎、抗关节炎作用。
TN6489 Regaloside A

Others Others
 Regaloside A 是一种从百合中提取出的苯丙烷,在 160 ppm 时显示出 DPPH 自由基清除活性。Regaloside A 具有抗炎活性和抗抑郁活性。
T2936 Antiarol

3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚

Others Others
3,4,5-Trimethoxyphenol 是一种提取自 Salmaliamalabaricum 中的天然化合物。
T39887 (S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸

Others Others
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid 是分离自间肠隐球菌培养基的代谢物,具有高的 DPPH 清除自由基活性和抗氧化活性。
T3852 Rhodiosin

AChE; Antioxidant Neuroscience; oxidation-reduction
Rhodiosin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50=27.7 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。
TN2011 Ombuoside

Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷

Antibacterial Microbiology/Virology
Ombuoside 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。
TN3972 Epimedokoreanin B

Apoptosis; Others; Antibacterial Apoptosis; Microbiology/Virology; Others
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。
TN3466 Atherosperminine

cAMP; Calcium Channel; Parasite; AChR GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
Atherosperminine 是一种天然生物碱,在体外表现出抗疟原虫活性,IC50为 5.80 μM。它具有DPPH 自由基清除活性,其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂,具有螯合金属的能力。
T8168 Hydroxytyrosol Acetate

3,4-二羟基苯乙醇醋酸,HTy-Ac

Antioxidant oxidation-reduction
Hydroxytyrosol acetate 是从橄榄油中发现的,具有抗氧化作用。它清除 DPPH 自由基的活性比 hydroxytyrosol 弱。
T5S0089 Kaempferol-3-O-glucorhamnoside

Kaempferol 3-glucorhamnoside,百蕊草素I

Antioxidant; p38 MAPK; NF-κB MAPK; NF-κB; oxidation-reduction
Kaempferol-3-O-glucorhamnoside 是来源于百蕊草的一种类黄酮,在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T5S0281 Tubuloside A

NOS Immunology/Inflammation
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。
T3S0006 (E)-Ferulic acid methyl ester

(E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate

NO Synthase; JNK; TNF; Antifection; p38 MAPK; IL Receptor; COX Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience
Methyl (E)-ferulate 具有较强 DPPH 和 ABTS+自由基清除特性。
TN1011 Rhodionin

P450; AChE Metabolism; Neuroscience
Rhodionin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50为 19.49 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。
T3388 Calycosin-7-O-β-D-glucoside

Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷

Reactive Oxygen Species; MMP Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
Calycosin-7-O-beta-D-glucoside 是一种异黄酮,从黄芪中分离得到。它具有多种生物活性,包括心脏保护、神经保护、抗炎和抗氧化作用。
T3899 Calceolarioside B

木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A

Aromatase Endocrinology/Hormones
Calceolarioside B 是一种分离自Stauntonia hexaphylla 叶片中的天然产物。它抑制 DPPH 自由基清除活性(IC50:94.60 μM)。它显著抑制大鼠晶状体醛糖还原酶(RLAR)活性(C50:23.99 μM。
T3676 Sesamol

3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Sesamol 是芝麻油的主要成分,具有抗氧化和抗肿瘤活性。它是一种自由基清除剂,在 DPPH 实验中,IC50为 5.95±0.56 μg/mL。
TN4754 Persicoside

Others Others
Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN3193 6-O-Vanilloylajugol

Others Others
6-O-Vanilloylajugol demonstrates scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN1207 2,4,7-Trihydroxy-9,10-dihydrophenanthrene

Others Others
2,4,7-Trihydroxy-9,10-dihydrophenanthrene showS the DPPH free radical scavenging activity with EC(50) from 8.8 to 55.9 microM.
TN3292 8-Prenyldaidzein

Others Others
8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging.
TN4000 Erythristemine

Others Others
(+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical.
TN2545 1-Hydroxypinoresinol 1-O-glucoside

ROS Immunology/Inflammation
(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively.
TMA0245 Hexacosyl (E)-ferulate

Others Others
Hexacosyl (E)-ferulate displays significant antioxidant activity in the DPPH assay (RC50 = 0.0976 mg/mL). It also might be a chemotaxonomic marker in the genus Echinops.
TN6414 Plantanone B

Plantanone C exhibited moderate antioxidant activity against DPPH radical scavenging activity,with an IC50 value of 240. 2 μmol·L~(-1).
TN3879 Docosyl caffeate

Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL.
TN1876 Lobetyolinin

党参炔苷宁

Others Others
Lobetyolinin exhibits DPPH radical scavenging activity.
TN4708 Olivil

Others Others
(-)-Olivil displays a higher antioxidative effect against the free radical DPPH.
TN5052 Ssioriside

Others Others
Ssioriside shows moderate antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.
TN4865 Putraflavone

Beta Amyloid; BACE Neuroscience
Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.
TN4617 N-trans-Feruloyl-3-methoxytyramine

Others Others
N-trans-Feruloyl-3-methoxytyramine shows significantly DPPH radical scavenging activities.
TN4445 Lobetyol

Others Others
Lobetyol shows significant antioxidant activity, it exhibits DPPH radical scavenging activity.
TN1802 Isoscoparin-2′′O-glucoside

Isoscoparin-2''-Beta-D-glucopyranoside,异金雀花素-2”-O-吡喃葡萄糖苷

Others Others
Isoscoparin-2''-Beta-D-glucopyranoside shows prominent free radical scavenging activity in DPPH assay.
TN2129 Quercetin-3-o-rutinose

Others Others
Quercetin-3-o-rutinose has antioxidative activity, it exerts strong DPPH radical-scavenging activity.
TN3444 Aristolactam BII

HIV Protease Microbiology/Virology; Proteases/Proteasome
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts its significant neuroprotective ef
TN4404 Ladanein

HCV Protease Microbiology/Virology; Proteases/Proteasome
Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities a
TN1896 Luteolin 5-O-glucoside

木犀草素-5-O-葡萄糖苷,藤黄菌素,Luteollin 5-glucoside

Others Others
Luteolin 5-O-α²-glucopyranoside has antioxidant activity, it can inhibit lipid peroxidation, and has DPPH radical-scavenging activity.
TN3902 Durantoside I

Others Others
Durantoside I has inhibitory activity on the growth of lettuce seedling. It also displays DPPH scavenging activity.
TN2240 Strictosidinic acid

Others Others
Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.
TN3381 Alnusdiol

Others Others
Alnusdiol exhibits the good scavenging activities against 2, 2-diphenyl-1-picryhydrazyl (DPPH), shows moderate anti-oxidant effects.
TN1689 Glabranine

Glabranin,光甘草宁

Antifection Microbiology/Virology
Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereof could be used to stimulate hair growth. Glabranine exerts a dose-dependent inhibitory effect
TN1796 Brassicin

油菜,异鼠李素-7-O-Β-D-葡萄糖苷,Isorhamnetin 7-O-glucoside

Others Others
Isorhamnetin 7-O-glucoside has antioxidant activity, it showed the peroxynitrite and DPPH scavenging activities with IC50 values of 2.07 /- 0.17 and 13.3 microM, respectively.
TN4711 Onitin

Others Others
Onitin shows super-oxide and DPPH free radical scavenging effects.It also exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.
TN2798 20-Deoxocarnosol

Antifection; ROS Immunology/Inflammation; Microbiology/Virology
20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity.
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天然产物

Rhamnocitrin
TN2151
synonym:
Target: Others
Vanillylmandelic acid
T0611
synonym: 3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid
Target: Others
Oxyresveratrol
T3S1068
synonym: Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇
Target: Tyrosinase, Autophagy, HSV
Effusol
TN1601
synonym: 灯心草菲酚,厄弗酚
Target: Caspase
Isookanin
TN1788
synonym:
Target: HSV, Others
Isobutylshikonin
TN1137
synonym:
Target: Others
Okanin
TN2008
synonym:
Target: TLR, NF-κB
Nepitrin
T2S1086
synonym: Nepetin-7-glucoside,假荆芥属苷
Target: Antioxidant
Regaloside A
TN6489
synonym:
Target: Others
Antiarol
T2936
synonym: 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚
Target: Others
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid
T39887
synonym: (S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸
Target: Others
Rhodiosin
T3852
synonym:
Target: AChE, Antioxidant
Ombuoside
TN2011
synonym: Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷
Target: Antibacterial
Epimedokoreanin B
TN3972
synonym:
Target: Apoptosis, Others, Antibacterial
Atherosperminine
TN3466
synonym:
Target: cAMP, Calcium Channel, Parasite, AChR
Hydroxytyrosol Acetate
T8168
synonym: 3,4-二羟基苯乙醇醋酸,HTy-Ac
Target: Antioxidant
Kaempferol-3-O-glucorhamnoside
T5S0089
synonym: Kaempferol 3-glucorhamnoside,百蕊草素I
Target: Antioxidant, p38 MAPK, NF-κB
Tubuloside A
T5S0281
synonym:
Target: NOS
(E)-Ferulic acid methyl ester
T3S0006
synonym: (E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate
Target: NO Synthase, JNK, TNF, Antifection, p38 MAPK, IL Receptor, COX
Rhodionin
TN1011
synonym:
Target: P450, AChE
Calycosin-7-O-β-D-glucoside
T3388
synonym: Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷
Target: Reactive Oxygen Species, MMP
Calceolarioside B
T3899
synonym: 木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A
Target: Aromatase
Sesamol
T3676
synonym: 3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚
Target: Apoptosis, AMPK
Persicoside
TN4754
synonym:
Target: Others
6-O-Vanilloylajugol
TN3193
synonym:
Target: Others
2,4,7-Trihydroxy-9,10-dihydrophenanthrene
TN1207
synonym:
Target: Others
8-Prenyldaidzein
TN3292
synonym:
Target: Others
Erythristemine
TN4000
synonym:
Target: Others
1-Hydroxypinoresinol 1-O-glucoside
TN2545
synonym:
Target: ROS
Hexacosyl (E)-ferulate
TMA0245
synonym:
Target: Others
Plantanone B
TN6414
synonym:
Target:
Docosyl caffeate
TN3879
synonym:
Target:
Lobetyolinin
TN1876
synonym: 党参炔苷宁
Target: Others
Olivil
TN4708
synonym:
Target: Others
Ssioriside
TN5052
synonym:
Target: Others
Putraflavone
TN4865
synonym:
Target: Beta Amyloid, BACE
N-trans-Feruloyl-3-methoxytyramine
TN4617
synonym:
Target: Others
Lobetyol
TN4445
synonym:
Target: Others
Isoscoparin-2′′O-glucoside
TN1802
synonym: Isoscoparin-2''-Beta-D-glucopyranoside,异金雀花素-2”-O-吡喃葡萄糖苷
Target: Others
Quercetin-3-o-rutinose
TN2129
synonym:
Target: Others
Aristolactam BII
TN3444
synonym:
Target: HIV Protease
Ladanein
TN4404
synonym:
Target: HCV Protease
Luteolin 5-O-glucoside
TN1896
synonym: 木犀草素-5-O-葡萄糖苷,藤黄菌素,Luteollin 5-glucoside
Target: Others
Durantoside I
TN3902
synonym:
Target: Others
Strictosidinic acid
TN2240
synonym:
Target: Others
Alnusdiol
TN3381
synonym:
Target: Others
Glabranine
TN1689
synonym: Glabranin,光甘草宁
Target: Antifection
Brassicin
TN1796
synonym: 油菜,异鼠李素-7-O-Β-D-葡萄糖苷,Isorhamnetin 7-O-glucoside
Target: Others
Onitin
TN4711
synonym:
Target: Others
20-Deoxocarnosol
TN2798
synonym:
Target: Antifection, ROS
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