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69
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11093 |
DPPH
2,2-联苯基-1-苦基肼基,2,2-Diphenyl-1-picrylhydrazyl |
Others | Others |
DPPH 是一种稳定的自由基,可用于测量抗氧化剂的自由基清除活性。DPPH 中氮原子的奇数电子通过从抗氧化剂吸收氢原子而还原为相应的肼。通过 DPPH 方法可用于水性和非极性有机溶剂中,检查亲水性和亲脂性抗氧化剂。 | |||
TN2151 | Rhamnocitrin | Others | Others |
Rhamnocitrin 是一种分离自黄芪(沙源子)中的类黄酮,具有抗氧化,抗炎和抗动脉粥样硬化活性。它是 DPPH 的清除剂(IC50:28.38 mM)。 | |||
T0611 |
Vanillylmandelic acid
3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid |
Others | Others |
4-Hydroxy-3-methoxymandelic acid 是肾上腺素和去甲肾上腺素代谢的最终产物。它具有抗氧化活性,可以清除 DPPH 自由基(IC50:33 μM)。它也是神经递质代谢紊乱的标志物。 | |||
T5728 |
OsMundacetone
4-(3,4-Dihydroxyphenyl)-3-buten-2-one |
Reactive Oxygen Species; Apoptosis | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB |
Osmundacetone 是从白桦茸中分离出的一种天然产物,具有抗凋亡作用。它具有DPPH 清除活性,保护神经细胞免受氧化应激,可研究神经退行性疾病。 | |||
T3S1068 |
Oxyresveratrol
Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇 |
Tyrosinase; Autophagy; HSV | Autophagy; Microbiology/Virology; Proteases/Proteasome |
Oxyresveratrol 是非竞争性酪氨酸酶抑制剂,对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1,HSV-2和水痘带状疱疹病毒,具有神经保护作用。它是天然抗氧化剂和自由基清除剂。 | |||
T9135 | Epirosmanol | Others | Others |
Epirosmanol 属于一类称为二萜内酯的有机化合物。这些是含有内酯部分的二萜类化合物。 Epirosmanol 是一种极弱碱性(基本中性)的化合物(基于其 pKa)。 | |||
T63750 | α-Amylase-IN-1 | Antioxidant | Metabolism; oxidation-reduction |
α-Amylase-IN-1 是一种 α-Amylase 抑制剂( IC50: 0.5509 μM)。α-Amylase-IN-1 具有抗氧化 (antioxidant) 活性,清除 DPPH 自由基的 IC50 值为 53.49 μM,可用于研究糖尿病和氧化应激相关疾病。 | |||
TN1601 |
Effusol
灯心草菲酚,厄弗酚 |
Caspase | Apoptosis; Proteases/Proteasome |
Effusol 是一种从 Juncus effuses 中分离到的酚类物质,对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP,保护海马功能对抗应激诱导的认知能力下降。 | |||
TN1788 | Isookanin | HSV; Others | Microbiology/Virology; Others |
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。 | |||
TN1137 | Isobutylshikonin | Others | Others |
Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。 | |||
TN2008 | Okanin | TLR; NF-κB | Immunology/Inflammation; NF-κB |
Okanin 是鬼针草中的一种有效成分,可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。 | |||
T2S1086 |
Nepitrin
Nepetin-7-glucoside,假荆芥属苷 |
Antioxidant | oxidation-reduction |
Nepitrin 分离自Scrophularia striata 中,具有强大的抗炎、抗关节炎作用。 | |||
TN6489 | Regaloside A | Others | Others |
Regaloside A 是一种从百合中提取出的苯丙烷,在 160 ppm 时显示出 DPPH 自由基清除活性。Regaloside A 具有抗炎活性和抗抑郁活性。 | |||
T2936 |
Antiarol
3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚 |
Others | Others |
3,4,5-Trimethoxyphenol 是一种提取自 Salmaliamalabaricum 中的天然化合物。 | |||
T39887 |
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid
(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸 |
Others | Others |
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid 是分离自间肠隐球菌培养基的代谢物,具有高的 DPPH 清除自由基活性和抗氧化活性。 | |||
T3852 | Rhodiosin | AChE; Antioxidant | Neuroscience; oxidation-reduction |
Rhodiosin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50=27.7 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。 | |||
TN2011 |
Ombuoside
Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷 |
Antibacterial | Microbiology/Virology |
Ombuoside 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。 | |||
TN3972 | Epimedokoreanin B | Apoptosis; Others; Antibacterial | Apoptosis; Microbiology/Virology; Others |
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。 | |||
TN3466 | Atherosperminine | cAMP; Calcium Channel; Parasite; AChR | GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience |
Atherosperminine 是一种天然生物碱,在体外表现出抗疟原虫活性,IC50为 5.80 μM。它具有DPPH 自由基清除活性,其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂,具有螯合金属的能力。 | |||
TN2211 |
Silybin B
Silibinin B |
Bcr-Abl; Beta Amyloid; Apoptosis | Angiogenesis; Apoptosis; Cytoskeletal Signaling; Neuroscience; Tyrosine Kinase/Adaptors |
Silybin B 是雷洛昔芬4′-和6-葡萄糖醛酸化的有效抑制剂,是水飞蓟素有效的抗纤维原性和抗低聚物成分,具有清除1,1-二苯基-2-吡啶酰肼(DPPH)自由基的活性 ,可通过减轻 DNA 损伤和细胞凋亡对顺铂诱导的神经毒性具有保护作用。Silybin B 对人慢性髓系白血病 K562细胞的生长抑制和诱导凋亡有较强的作用,是减轻顺铂所致的脑神经损伤的候选化合物。 | |||
T8168 |
Hydroxytyrosol Acetate
3,4-二羟基苯乙醇醋酸,HTy-Ac |
Antioxidant | oxidation-reduction |
Hydroxytyrosol acetate 是从橄榄油中发现的,具有抗氧化作用。它清除 DPPH 自由基的活性比 hydroxytyrosol 弱。 | |||
T5S0089 |
Kaempferol-3-O-glucorhamnoside
Kaempferol 3-glucorhamnoside,百蕊草素I |
Antioxidant; p38 MAPK; NF-κB | MAPK; NF-κB; oxidation-reduction |
Kaempferol-3-O-glucorhamnoside 是来源于百蕊草的一种类黄酮,在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。 | |||
T5S0281 | Tubuloside A | NOS | Immunology/Inflammation |
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。 | |||
T3S0006 |
(E)-Ferulic acid methyl ester
(E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate |
NO Synthase; JNK; TNF; Antifection; p38 MAPK; IL Receptor; COX | Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience |
Methyl (E)-ferulate 具有较强 DPPH 和 ABTS+自由基清除特性。 | |||
TN1011 | Rhodionin | P450; AChE | Metabolism; Neuroscience |
Rhodionin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50为 19.49 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。 | |||
T3388 |
Calycosin-7-O-β-D-glucoside
Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷 |
Reactive Oxygen Species; MMP | Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome |
Calycosin-7-O-beta-D-glucoside 是一种异黄酮,从黄芪中分离得到。它具有多种生物活性,包括心脏保护、神经保护、抗炎和抗氧化作用。 | |||
T3899 |
Calceolarioside B
木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A |
Aromatase | Endocrinology/Hormones |
Calceolarioside B 是一种分离自Stauntonia hexaphylla 叶片中的天然产物。它抑制 DPPH 自由基清除活性(IC50:94.60 μM)。它显著抑制大鼠晶状体醛糖还原酶(RLAR)活性(C50:23.99 μM。 | |||
T13350 | Wushanicaritin | Others | Others |
Wushanicaritin 在 DPPH 自由基清除活性测试中显示出显著的抗氧化活性 ,其IC50值为35.3 μM,具有抗肿瘤作用和抗炎活性。 | |||
T8895 | Altenusin | FXR | Metabolism |
Altenusin 是天然的非甾体真菌代谢物,是新型 FXR 选择性激动剂,EC50 值为 3.2 ± 0.2 μM。它具有明显的 DPPH 自由基清除活性。 | |||
T37710 | 5-Hydroxyoxindole | Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
5-Hydroxyoxindole 是尿酸的一种结构类似物,具有脂质过氧化抑制活性和自由基 DPPH 清除活性,可用于氧化应激介导的疾病的研究。 | |||
T3676 |
Sesamol
3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚 |
Apoptosis; AMPK | Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Sesamol 是芝麻油的主要成分,具有抗氧化和抗肿瘤活性。它是一种自由基清除剂,在 DPPH 实验中,IC50为 5.95±0.56 μg/mL。 | |||
TN4469 | Lyoniresinol | ||
Lyoniresinol 是一种从 Tarenna attenuata 分离出来的木质素,具有清除自由基的活性(IC50为82.4μM)和 DPPH 的抗氧化活性,显示出抗黑色素生成活性。Lyoniresinol 有强烈的苦味,而其对映体(-)-Lyoniresinol 是无味的。 | |||
TN4754 | Persicoside | Others | Others |
Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. | |||
TN3193 | 6-O-Vanilloylajugol | Others | Others |
6-O-Vanilloylajugol demonstrates scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. | |||
TN1207 | 2,4,7-Trihydroxy-9,10-dihydrophenanthrene | Others | Others |
2,4,7-Trihydroxy-9,10-dihydrophenanthrene showS the DPPH free radical scavenging activity with EC(50) from 8.8 to 55.9 microM. | |||
T13598 | Caulophylline B | Others | Others |
Caulophylline B, an alkaloid extracted from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical. | |||
T75477 | Epicoccone B | ||
Epicoccone B 首次报道于C.globosum,具有清除 DPPH 自由基的能力,IC50值为10.8 μM,并具有有效的 α-葡萄糖苷酶抑制作用,IC50值为 27.3 μM。具有抗HIV 活性。 | |||
TN1734 |
Heveaflavone
橡胶树双黄酮 |
Antioxidant; Topoisomerase | DNA Damage/DNA Repair; oxidation-reduction |
Heveaflavone 抑制拓扑异构酶 I 并清除 DPPH 自由基,具有抗增殖和抗氧化作用。 | |||
TN3292 | 8-Prenyldaidzein | Others | Others |
8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging. | |||
TN4000 | Erythristemine | Others | Others |
(+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical. | |||
TN2545 | 1-Hydroxypinoresinol 1-O-glucoside | ROS | Immunology/Inflammation |
(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively. | |||
TMA0245 | Hexacosyl (E)-ferulate | Others | Others |
Hexacosyl (E)-ferulate displays significant antioxidant activity in the DPPH assay (RC50 = 0.0976 mg/mL). It also might be a chemotaxonomic marker in the genus Echinops. | |||
TN6414 | Plantanone B | ||
Plantanone C exhibited moderate antioxidant activity against DPPH radical scavenging activity,with an IC50 value of 240. 2 μmol·L~(-1). | |||
TN3061 | 4'-O-Methyllicoflavanone | Antioxidant | oxidation-reduction |
4'-O-Methyllicoflavanone 是从 Erythrina orientalis 的茎皮中分离得到的,对 DPPH 自由基具有抗氧化活性,IC50 值为 648.1 μM。 | |||
TN3879 | Docosyl caffeate | ||
Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL. | |||
TN1876 |
Lobetyolinin
党参炔苷宁 |
Others | Others |
Lobetyolinin exhibits DPPH radical scavenging activity. | |||
TN4708 | Olivil | Others | Others |
(-)-Olivil displays a higher antioxidative effect against the free radical DPPH. | |||
TN5052 | Ssioriside | Others | Others |
Ssioriside shows moderate antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. | |||
TN4865 | Putraflavone | Beta Amyloid; BACE | Neuroscience |
Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging. | |||
TN4617 | N-trans-Feruloyl-3-methoxytyramine | Others | Others |
N-trans-Feruloyl-3-methoxytyramine shows significantly DPPH radical scavenging activities. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2151 | Rhamnocitrin | Others | Others |
Rhamnocitrin 是一种分离自黄芪(沙源子)中的类黄酮,具有抗氧化,抗炎和抗动脉粥样硬化活性。它是 DPPH 的清除剂(IC50:28.38 mM)。 | |||
T0611 |
Vanillylmandelic acid
3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid |
Others | Others |
4-Hydroxy-3-methoxymandelic acid 是肾上腺素和去甲肾上腺素代谢的最终产物。它具有抗氧化活性,可以清除 DPPH 自由基(IC50:33 μM)。它也是神经递质代谢紊乱的标志物。 | |||
T3S1068 |
Oxyresveratrol
Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇 |
Tyrosinase; Autophagy; HSV | Autophagy; Microbiology/Virology; Proteases/Proteasome |
Oxyresveratrol 是非竞争性酪氨酸酶抑制剂,对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1,HSV-2和水痘带状疱疹病毒,具有神经保护作用。它是天然抗氧化剂和自由基清除剂。 | |||
TN1601 |
Effusol
灯心草菲酚,厄弗酚 |
Caspase | Apoptosis; Proteases/Proteasome |
Effusol 是一种从 Juncus effuses 中分离到的酚类物质,对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP,保护海马功能对抗应激诱导的认知能力下降。 | |||
TN1788 | Isookanin | HSV; Others | Microbiology/Virology; Others |
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。 | |||
TN1137 | Isobutylshikonin | Others | Others |
Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。 | |||
TN2008 | Okanin | TLR; NF-κB | Immunology/Inflammation; NF-κB |
Okanin 是鬼针草中的一种有效成分,可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。 | |||
T2S1086 |
Nepitrin
Nepetin-7-glucoside,假荆芥属苷 |
Antioxidant | oxidation-reduction |
Nepitrin 分离自Scrophularia striata 中,具有强大的抗炎、抗关节炎作用。 | |||
TN6489 | Regaloside A | Others | Others |
Regaloside A 是一种从百合中提取出的苯丙烷,在 160 ppm 时显示出 DPPH 自由基清除活性。Regaloside A 具有抗炎活性和抗抑郁活性。 | |||
T2936 |
Antiarol
3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚 |
Others | Others |
3,4,5-Trimethoxyphenol 是一种提取自 Salmaliamalabaricum 中的天然化合物。 | |||
T39887 |
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid
(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸 |
Others | Others |
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid 是分离自间肠隐球菌培养基的代谢物,具有高的 DPPH 清除自由基活性和抗氧化活性。 | |||
T3852 | Rhodiosin | AChE; Antioxidant | Neuroscience; oxidation-reduction |
Rhodiosin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50=27.7 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。 | |||
TN2011 |
Ombuoside
Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷 |
Antibacterial | Microbiology/Virology |
Ombuoside 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。 | |||
TN3972 | Epimedokoreanin B | Apoptosis; Others; Antibacterial | Apoptosis; Microbiology/Virology; Others |
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。 | |||
TN3466 | Atherosperminine | cAMP; Calcium Channel; Parasite; AChR | GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience |
Atherosperminine 是一种天然生物碱,在体外表现出抗疟原虫活性,IC50为 5.80 μM。它具有DPPH 自由基清除活性,其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂,具有螯合金属的能力。 | |||
T8168 |
Hydroxytyrosol Acetate
3,4-二羟基苯乙醇醋酸,HTy-Ac |
Antioxidant | oxidation-reduction |
Hydroxytyrosol acetate 是从橄榄油中发现的,具有抗氧化作用。它清除 DPPH 自由基的活性比 hydroxytyrosol 弱。 | |||
T5S0089 |
Kaempferol-3-O-glucorhamnoside
Kaempferol 3-glucorhamnoside,百蕊草素I |
Antioxidant; p38 MAPK; NF-κB | MAPK; NF-κB; oxidation-reduction |
Kaempferol-3-O-glucorhamnoside 是来源于百蕊草的一种类黄酮,在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。 | |||
T5S0281 | Tubuloside A | NOS | Immunology/Inflammation |
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。 | |||
T3S0006 |
(E)-Ferulic acid methyl ester
(E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate |
NO Synthase; JNK; TNF; Antifection; p38 MAPK; IL Receptor; COX | Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience |
Methyl (E)-ferulate 具有较强 DPPH 和 ABTS+自由基清除特性。 | |||
TN1011 | Rhodionin | P450; AChE | Metabolism; Neuroscience |
Rhodionin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂,IC50=0.761 μM,Ki=0.769 μM。它有 DPPH 自由基清除活性,IC50为 19.49 μM。它抑制乙酰胆碱酯酶,IC50范围为 57.50 至 2.43 μg/mL。 | |||
T3388 |
Calycosin-7-O-β-D-glucoside
Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷 |
Reactive Oxygen Species; MMP | Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome |
Calycosin-7-O-beta-D-glucoside 是一种异黄酮,从黄芪中分离得到。它具有多种生物活性,包括心脏保护、神经保护、抗炎和抗氧化作用。 | |||
T3899 |
Calceolarioside B
木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A |
Aromatase | Endocrinology/Hormones |
Calceolarioside B 是一种分离自Stauntonia hexaphylla 叶片中的天然产物。它抑制 DPPH 自由基清除活性(IC50:94.60 μM)。它显著抑制大鼠晶状体醛糖还原酶(RLAR)活性(C50:23.99 μM。 | |||
T3676 |
Sesamol
3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚 |
Apoptosis; AMPK | Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Sesamol 是芝麻油的主要成分,具有抗氧化和抗肿瘤活性。它是一种自由基清除剂,在 DPPH 实验中,IC50为 5.95±0.56 μg/mL。 | |||
TN4754 | Persicoside | Others | Others |
Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. | |||
TN3193 | 6-O-Vanilloylajugol | Others | Others |
6-O-Vanilloylajugol demonstrates scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. | |||
TN1207 | 2,4,7-Trihydroxy-9,10-dihydrophenanthrene | Others | Others |
2,4,7-Trihydroxy-9,10-dihydrophenanthrene showS the DPPH free radical scavenging activity with EC(50) from 8.8 to 55.9 microM. | |||
TN3292 | 8-Prenyldaidzein | Others | Others |
8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging. | |||
TN4000 | Erythristemine | Others | Others |
(+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical. | |||
TN2545 | 1-Hydroxypinoresinol 1-O-glucoside | ROS | Immunology/Inflammation |
(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively. | |||
TMA0245 | Hexacosyl (E)-ferulate | Others | Others |
Hexacosyl (E)-ferulate displays significant antioxidant activity in the DPPH assay (RC50 = 0.0976 mg/mL). It also might be a chemotaxonomic marker in the genus Echinops. | |||
TN6414 | Plantanone B | ||
Plantanone C exhibited moderate antioxidant activity against DPPH radical scavenging activity,with an IC50 value of 240. 2 μmol·L~(-1). | |||
TN3879 | Docosyl caffeate | ||
Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL. | |||
TN1876 |
Lobetyolinin
党参炔苷宁 |
Others | Others |
Lobetyolinin exhibits DPPH radical scavenging activity. | |||
TN4708 | Olivil | Others | Others |
(-)-Olivil displays a higher antioxidative effect against the free radical DPPH. | |||
TN5052 | Ssioriside | Others | Others |
Ssioriside shows moderate antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. | |||
TN4865 | Putraflavone | Beta Amyloid; BACE | Neuroscience |
Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging. | |||
TN4617 | N-trans-Feruloyl-3-methoxytyramine | Others | Others |
N-trans-Feruloyl-3-methoxytyramine shows significantly DPPH radical scavenging activities. | |||
TN4445 | Lobetyol | Others | Others |
Lobetyol shows significant antioxidant activity, it exhibits DPPH radical scavenging activity. | |||
TN1802 |
Isoscoparin-2′′O-glucoside
Isoscoparin-2''-Beta-D-glucopyranoside,异金雀花素-2”-O-吡喃葡萄糖苷 |
Others | Others |
Isoscoparin-2''-Beta-D-glucopyranoside shows prominent free radical scavenging activity in DPPH assay. | |||
TN2129 | Quercetin-3-o-rutinose | Others | Others |
Quercetin-3-o-rutinose has antioxidative activity, it exerts strong DPPH radical-scavenging activity. | |||
TN3444 | Aristolactam BII | HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts its significant neuroprotective ef | |||
TN4404 | Ladanein | HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities a | |||
TN1896 |
Luteolin 5-O-glucoside
木犀草素-5-O-葡萄糖苷,藤黄菌素,Luteollin 5-glucoside |
Others | Others |
Luteolin 5-O-α²-glucopyranoside has antioxidant activity, it can inhibit lipid peroxidation, and has DPPH radical-scavenging activity. | |||
TN3902 | Durantoside I | Others | Others |
Durantoside I has inhibitory activity on the growth of lettuce seedling. It also displays DPPH scavenging activity. | |||
TN2240 | Strictosidinic acid | Others | Others |
Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system. | |||
TN3381 | Alnusdiol | Others | Others |
Alnusdiol exhibits the good scavenging activities against 2, 2-diphenyl-1-picryhydrazyl (DPPH), shows moderate anti-oxidant effects. | |||
TN1689 |
Glabranine
Glabranin,光甘草宁 |
Antifection | Microbiology/Virology |
Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereof could be used to stimulate hair growth. Glabranine exerts a dose-dependent inhibitory effect | |||
TN1796 |
Brassicin
油菜,异鼠李素-7-O-Β-D-葡萄糖苷,Isorhamnetin 7-O-glucoside |
Others | Others |
Isorhamnetin 7-O-glucoside has antioxidant activity, it showed the peroxynitrite and DPPH scavenging activities with IC50 values of 2.07 /- 0.17 and 13.3 microM, respectively. | |||
TN4711 | Onitin | Others | Others |
Onitin shows super-oxide and DPPH free radical scavenging effects.It also exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. | |||
TN2798 | 20-Deoxocarnosol | Antifection; ROS | Immunology/Inflammation; Microbiology/Virology |
20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity. | |||
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