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Search Results for "dpph"

Targets Recommended: Others

99

抑制剂 & 化合物

69

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T11093	DPPH 2,2-联苯基-1-苦基肼基,2,2-Diphenyl-1-picrylhydrazyl	Others	Others
	DPPH 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。DPPH 中氮原子的奇数电子通过从抗氧化剂吸收氢原子而还原为相应的肼。通过 DPPH 方法可用于水性和非极性有机溶剂中，检查亲水性和亲脂性抗氧化剂。
TN2151	Rhamnocitrin	Others	Others
	Rhamnocitrin 是一种分离自黄芪(沙源子)中的类黄酮，具有抗氧化，抗炎和抗动脉粥样硬化活性。它是 DPPH 的清除剂(IC50:28.38 mM)。
T0611	Vanillylmandelic acid 3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid	Others	Others
	4-Hydroxy-3-methoxymandelic acid 是肾上腺素和去甲肾上腺素代谢的最终产物。它具有抗氧化活性，可以清除 DPPH 自由基(IC50:33 μM)。它也是神经递质代谢紊乱的标志物。
T5728	OsMundacetone 4-(3,4-Dihydroxyphenyl)-3-buten-2-one	Reactive Oxygen Species; Apoptosis	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Osmundacetone 是从白桦茸中分离出的一种天然产物，具有抗凋亡作用。它具有DPPH 清除活性，保护神经细胞免受氧化应激，可研究神经退行性疾病。
T3S1068	Oxyresveratrol Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇	Tyrosinase; Autophagy; HSV	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Oxyresveratrol 是非竞争性酪氨酸酶抑制剂，对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1，HSV-2和水痘带状疱疹病毒，具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T9135	Epirosmanol	Others	Others
	Epirosmanol 属于一类称为二萜内酯的有机化合物。这些是含有内酯部分的二萜类化合物。 Epirosmanol 是一种极弱碱性（基本中性）的化合物（基于其 pKa）。
T63750	α-Amylase-IN-1	Antioxidant	Metabolism; oxidation-reduction
	α-Amylase-IN-1 是一种 α-Amylase 抑制剂（ IC50： 0.5509 μM）。α-Amylase-IN-1 具有抗氧化 (antioxidant) 活性，清除 DPPH 自由基的 IC50 值为 53.49 μM，可用于研究糖尿病和氧化应激相关疾病。
TN1601	Effusol 灯心草菲酚,厄弗酚	Caspase	Apoptosis; Proteases/Proteasome
	Effusol 是一种从 Juncus effuses 中分离到的酚类物质，对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP，保护海马功能对抗应激诱导的认知能力下降。
TN1788	Isookanin	HSV; Others	Microbiology/Virology; Others
	Isookanin 在多种疾病领域有研究价值，包括肿瘤，皮疹，蛇和昆虫叮咬，糖尿病，腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。
TN1137	Isobutylshikonin	Others	Others
	Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。
TN2008	Okanin	TLR; NF-κB	Immunology/Inflammation; NF-κB
	Okanin 是鬼针草中的一种有效成分，可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。
T2S1086	Nepitrin Nepetin-7-glucoside,假荆芥属苷	Antioxidant	oxidation-reduction
	Nepitrin 分离自Scrophularia striata 中，具有强大的抗炎、抗关节炎作用。
TN6489	Regaloside A	Others	Others
	Regaloside A 是一种从百合中提取出的苯丙烷，在 160 ppm 时显示出 DPPH 自由基清除活性。Regaloside A 具有抗炎活性和抗抑郁活性。
T2936	Antiarol 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚	Others	Others
	3,4,5-Trimethoxyphenol 是一种提取自 Salmaliamalabaricum 中的天然化合物。
T39887	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid (S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸	Others	Others
	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid 是分离自间肠隐球菌培养基的代谢物，具有高的 DPPH 清除自由基活性和抗氧化活性。
T3852	Rhodiosin	AChE; Antioxidant	Neuroscience; oxidation-reduction
	Rhodiosin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂，IC50=0.761 μM，Ki=0.769 μM。它有 DPPH 自由基清除活性，IC50=27.7 μM。它抑制乙酰胆碱酯酶，IC50范围为 57.50 至 2.43 μg/mL。
TN2011	Ombuoside Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷	Antibacterial	Microbiology/Virology
	Ombuoside 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。
TN3972	Epimedokoreanin B	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Epimedokoreanin B （EKB）是一种从韩国淫羊藿中分离出的异戊烯化类黄酮，在人非小细胞肺癌（NSCLC）A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性，可有清除 DPPH 自由基的活性，能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -（羧甲基）赖氨酸（CML）和 N (Ï) -（羧甲基）精氨酸（CMA）的形成，可通过抑制高级糖化终产物（AGEs）预防糖尿病的临床并发症。
TN3466	Atherosperminine	cAMP; Calcium Channel; Parasite; AChR	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	Atherosperminine 是一种天然生物碱，在体外表现出抗疟原虫活性，IC50为 5.80 μM。它具有DPPH 自由基清除活性，其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂，具有螯合金属的能力。
TN2211	Silybin B Silibinin B	Bcr-Abl; Beta Amyloid; Apoptosis	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Neuroscience; Tyrosine Kinase/Adaptors
	Silybin B 是雷洛昔芬4′-和6-葡萄糖醛酸化的有效抑制剂，是水飞蓟素有效的抗纤维原性和抗低聚物成分，具有清除1,1-二苯基-2-吡啶酰肼(DPPH)自由基的活性，可通过减轻 DNA 损伤和细胞凋亡对顺铂诱导的神经毒性具有保护作用。Silybin B 对人慢性髓系白血病 K562细胞的生长抑制和诱导凋亡有较强的作用，是减轻顺铂所致的脑神经损伤的候选化合物。
T8168	Hydroxytyrosol Acetate 3,4-二羟基苯乙醇醋酸,HTy-Ac	Antioxidant	oxidation-reduction
	Hydroxytyrosol acetate 是从橄榄油中发现的，具有抗氧化作用。它清除 DPPH 自由基的活性比 hydroxytyrosol 弱。
T5S0089	Kaempferol-3-O-glucorhamnoside Kaempferol 3-glucorhamnoside,百蕊草素I	Antioxidant; p38 MAPK; NF-κB	MAPK; NF-κB; oxidation-reduction
	Kaempferol-3-O-glucorhamnoside 是来源于百蕊草的一种类黄酮，在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T5S0281	Tubuloside A	NOS	Immunology/Inflammation
	Tubuloside A 是一种苯乙醇苷，具有抗氧化活性和保肝活性。
T3S0006	(E)-Ferulic acid methyl ester (E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate	NO Synthase; JNK; TNF; Antifection; p38 MAPK; IL Receptor; COX	Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience
	Methyl (E)-ferulate 具有较强 DPPH 和 ABTS+自由基清除特性。
TN1011	Rhodionin	P450; AChE	Metabolism; Neuroscience
	Rhodionin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂，IC50=0.761 μM，Ki=0.769 μM。它有 DPPH 自由基清除活性，IC50为 19.49 μM。它抑制乙酰胆碱酯酶，IC50范围为 57.50 至 2.43 μg/mL。
T3388	Calycosin-7-O-β-D-glucoside Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷	Reactive Oxygen Species; MMP	Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
	Calycosin-7-O-beta-D-glucoside 是一种异黄酮，从黄芪中分离得到。它具有多种生物活性，包括心脏保护、神经保护、抗炎和抗氧化作用。
T3899	Calceolarioside B 木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A	Aromatase	Endocrinology/Hormones
	Calceolarioside B 是一种分离自Stauntonia hexaphylla 叶片中的天然产物。它抑制 DPPH 自由基清除活性(IC50:94.60 μM)。它显著抑制大鼠晶状体醛糖还原酶(RLAR)活性(C50:23.99 μM。
T13350	Wushanicaritin	Others	Others
	Wushanicaritin 在 DPPH 自由基清除活性测试中显示出显著的抗氧化活性，其IC50值为35.3 μM，具有抗肿瘤作用和抗炎活性。
T8895	Altenusin	FXR	Metabolism
	Altenusin 是天然的非甾体真菌代谢物，是新型 FXR 选择性激动剂，EC50 值为 3.2 ± 0.2 μM。它具有明显的 DPPH 自由基清除活性。
T37710	5-Hydroxyoxindole	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	5-Hydroxyoxindole 是尿酸的一种结构类似物，具有脂质过氧化抑制活性和自由基 DPPH 清除活性，可用于氧化应激介导的疾病的研究。
T3676	Sesamol 3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚	Apoptosis; AMPK	Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Sesamol 是芝麻油的主要成分，具有抗氧化和抗肿瘤活性。它是一种自由基清除剂，在 DPPH 实验中，IC50为 5.95±0.56 μg/mL。
TN4469	Lyoniresinol
	Lyoniresinol 是一种从 Tarenna attenuata 分离出来的木质素，具有清除自由基的活性（IC50为82.4μM）和 DPPH 的抗氧化活性，显示出抗黑色素生成活性。Lyoniresinol 有强烈的苦味，而其对映体(-)-Lyoniresinol 是无味的。
TN4754	Persicoside	Others	Others
	Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN3193	6-O-Vanilloylajugol	Others	Others
	6-O-Vanilloylajugol demonstrates scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN1207	2,4,7-Trihydroxy-9,10-dihydrophenanthrene	Others	Others
	2,4,7-Trihydroxy-9,10-dihydrophenanthrene showS the DPPH free radical scavenging activity with EC(50) from 8.8 to 55.9 microM.
T13598	Caulophylline B	Others	Others
	Caulophylline B, an alkaloid extracted from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical.
T75477	Epicoccone B
	Epicoccone B 首次报道于C.globosum，具有清除 DPPH 自由基的能力，IC50值为10.8 μM，并具有有效的 α-葡萄糖苷酶抑制作用，IC50值为 27.3 μM。具有抗HIV 活性。
TN1734	Heveaflavone 橡胶树双黄酮	Antioxidant; Topoisomerase	DNA Damage/DNA Repair; oxidation-reduction
	Heveaflavone 抑制拓扑异构酶 I 并清除 DPPH 自由基，具有抗增殖和抗氧化作用。
TN3292	8-Prenyldaidzein	Others	Others
	8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging.
TN4000	Erythristemine	Others	Others
	(+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical.
TN2545	1-Hydroxypinoresinol 1-O-glucoside	ROS	Immunology/Inflammation
	(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively.
TMA0245	Hexacosyl (E)-ferulate	Others	Others
	Hexacosyl (E)-ferulate displays significant antioxidant activity in the DPPH assay (RC50 = 0.0976 mg/mL). It also might be a chemotaxonomic marker in the genus Echinops.
TN6414	Plantanone B
	Plantanone C exhibited moderate antioxidant activity against DPPH radical scavenging activity,with an IC50 value of 240. 2 μmol·L~(-1).
TN3061	4'-O-Methyllicoflavanone	Antioxidant	oxidation-reduction
	4'-O-Methyllicoflavanone 是从 Erythrina orientalis 的茎皮中分离得到的，对 DPPH 自由基具有抗氧化活性，IC50 值为 648.1 μM。
TN3879	Docosyl caffeate
	Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL.
TN1876	Lobetyolinin 党参炔苷宁	Others	Others
	Lobetyolinin exhibits DPPH radical scavenging activity.
TN4708	Olivil	Others	Others
	(-)-Olivil displays a higher antioxidative effect against the free radical DPPH.
TN5052	Ssioriside	Others	Others
	Ssioriside shows moderate antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.
TN4865	Putraflavone	Beta Amyloid; BACE	Neuroscience
	Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.
TN4617	N-trans-Feruloyl-3-methoxytyramine	Others	Others
	N-trans-Feruloyl-3-methoxytyramine shows significantly DPPH radical scavenging activities.

化合物

synonym: 2,2-联苯基-1-苦基肼基,2,2-Diphenyl-1-picrylhydrazyl

Vanillylmandelic acid

synonym: 3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid

synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Target: Reactive Oxygen Species, Apoptosis

synonym: Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇

Target: Tyrosinase, Autophagy, HSV

α-Amylase-IN-1

Target: Antioxidant

synonym: 灯心草菲酚,厄弗酚

Target: Caspase

Target: HSV, Others

Isobutylshikonin

Target: TLR, NF-κB

synonym: Nepetin-7-glucoside,假荆芥属苷

Target: Antioxidant

synonym: 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚

(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

synonym: (S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸

Target: AChE, Antioxidant

synonym: Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷

Target: Antibacterial

Epimedokoreanin B

Target: Apoptosis, Others, Antibacterial

Atherosperminine

Target: cAMP, Calcium Channel, Parasite, AChR

synonym: Silibinin B

Target: Bcr-Abl, Beta Amyloid, Apoptosis

Hydroxytyrosol Acetate

synonym: 3,4-二羟基苯乙醇醋酸,HTy-Ac

Target: Antioxidant

Kaempferol-3-O-glucorhamnoside

synonym: Kaempferol 3-glucorhamnoside,百蕊草素I

Target: Antioxidant, p38 MAPK, NF-κB

(E)-Ferulic acid methyl ester

synonym: (E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate

Target: NO Synthase, JNK, TNF, Antifection, p38 MAPK, IL Receptor, COX

Target: P450, AChE

Calycosin-7-O-β-D-glucoside

synonym: Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷

Target: Reactive Oxygen Species, MMP

Calceolarioside B

synonym: 木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A

Target: Aromatase

5-Hydroxyoxindole

Target: Reactive Oxygen Species

synonym: 3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚

Target: Apoptosis, AMPK

6-O-Vanilloylajugol

2,4,7-Trihydroxy-9,10-dihydrophenanthrene

Caulophylline B

synonym: 橡胶树双黄酮

Target: Antioxidant, Topoisomerase

8-Prenyldaidzein

1-Hydroxypinoresinol 1-O-glucoside

Hexacosyl (E)-ferulate

4'-O-Methyllicoflavanone

Target: Antioxidant

Docosyl caffeate

synonym: 党参炔苷宁

Target: Beta Amyloid, BACE

N-trans-Feruloyl-3-methoxytyramine

Cat. No.	Product Name	Target	Signaling Pathways
TN2151	Rhamnocitrin	Others	Others
	Rhamnocitrin 是一种分离自黄芪(沙源子)中的类黄酮，具有抗氧化，抗炎和抗动脉粥样硬化活性。它是 DPPH 的清除剂(IC50:28.38 mM)。
T0611	Vanillylmandelic acid 3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid	Others	Others
	4-Hydroxy-3-methoxymandelic acid 是肾上腺素和去甲肾上腺素代谢的最终产物。它具有抗氧化活性，可以清除 DPPH 自由基(IC50:33 μM)。它也是神经递质代谢紊乱的标志物。
T3S1068	Oxyresveratrol Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇	Tyrosinase; Autophagy; HSV	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Oxyresveratrol 是非竞争性酪氨酸酶抑制剂，对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1，HSV-2和水痘带状疱疹病毒，具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
TN1601	Effusol 灯心草菲酚,厄弗酚	Caspase	Apoptosis; Proteases/Proteasome
	Effusol 是一种从 Juncus effuses 中分离到的酚类物质，对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP，保护海马功能对抗应激诱导的认知能力下降。
TN1788	Isookanin	HSV; Others	Microbiology/Virology; Others
	Isookanin 在多种疾病领域有研究价值，包括肿瘤，皮疹，蛇和昆虫叮咬，糖尿病，腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。
TN1137	Isobutylshikonin	Others	Others
	Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。
TN2008	Okanin	TLR; NF-κB	Immunology/Inflammation; NF-κB
	Okanin 是鬼针草中的一种有效成分，可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。
T2S1086	Nepitrin Nepetin-7-glucoside,假荆芥属苷	Antioxidant	oxidation-reduction
	Nepitrin 分离自Scrophularia striata 中，具有强大的抗炎、抗关节炎作用。
TN6489	Regaloside A	Others	Others
	Regaloside A 是一种从百合中提取出的苯丙烷，在 160 ppm 时显示出 DPPH 自由基清除活性。Regaloside A 具有抗炎活性和抗抑郁活性。
T2936	Antiarol 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚	Others	Others
	3,4,5-Trimethoxyphenol 是一种提取自 Salmaliamalabaricum 中的天然化合物。
T39887	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid (S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸	Others	Others
	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid 是分离自间肠隐球菌培养基的代谢物，具有高的 DPPH 清除自由基活性和抗氧化活性。
T3852	Rhodiosin	AChE; Antioxidant	Neuroscience; oxidation-reduction
	Rhodiosin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂，IC50=0.761 μM，Ki=0.769 μM。它有 DPPH 自由基清除活性，IC50=27.7 μM。它抑制乙酰胆碱酯酶，IC50范围为 57.50 至 2.43 μg/mL。
TN2011	Ombuoside Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷	Antibacterial	Microbiology/Virology
	Ombuoside 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。
TN3972	Epimedokoreanin B	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Epimedokoreanin B （EKB）是一种从韩国淫羊藿中分离出的异戊烯化类黄酮，在人非小细胞肺癌（NSCLC）A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性，可有清除 DPPH 自由基的活性，能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -（羧甲基）赖氨酸（CML）和 N (Ï) -（羧甲基）精氨酸（CMA）的形成，可通过抑制高级糖化终产物（AGEs）预防糖尿病的临床并发症。
TN3466	Atherosperminine	cAMP; Calcium Channel; Parasite; AChR	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	Atherosperminine 是一种天然生物碱，在体外表现出抗疟原虫活性，IC50为 5.80 μM。它具有DPPH 自由基清除活性，其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂，具有螯合金属的能力。
T8168	Hydroxytyrosol Acetate 3,4-二羟基苯乙醇醋酸,HTy-Ac	Antioxidant	oxidation-reduction
	Hydroxytyrosol acetate 是从橄榄油中发现的，具有抗氧化作用。它清除 DPPH 自由基的活性比 hydroxytyrosol 弱。
T5S0089	Kaempferol-3-O-glucorhamnoside Kaempferol 3-glucorhamnoside,百蕊草素I	Antioxidant; p38 MAPK; NF-κB	MAPK; NF-κB; oxidation-reduction
	Kaempferol-3-O-glucorhamnoside 是来源于百蕊草的一种类黄酮，在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T5S0281	Tubuloside A	NOS	Immunology/Inflammation
	Tubuloside A 是一种苯乙醇苷，具有抗氧化活性和保肝活性。
T3S0006	(E)-Ferulic acid methyl ester (E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate	NO Synthase; JNK; TNF; Antifection; p38 MAPK; IL Receptor; COX	Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience
	Methyl (E)-ferulate 具有较强 DPPH 和 ABTS+自由基清除特性。
TN1011	Rhodionin	P450; AChE	Metabolism; Neuroscience
	Rhodionin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂，IC50=0.761 μM，Ki=0.769 μM。它有 DPPH 自由基清除活性，IC50为 19.49 μM。它抑制乙酰胆碱酯酶，IC50范围为 57.50 至 2.43 μg/mL。
T3388	Calycosin-7-O-β-D-glucoside Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷	Reactive Oxygen Species; MMP	Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
	Calycosin-7-O-beta-D-glucoside 是一种异黄酮，从黄芪中分离得到。它具有多种生物活性，包括心脏保护、神经保护、抗炎和抗氧化作用。
T3899	Calceolarioside B 木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A	Aromatase	Endocrinology/Hormones
	Calceolarioside B 是一种分离自Stauntonia hexaphylla 叶片中的天然产物。它抑制 DPPH 自由基清除活性(IC50:94.60 μM)。它显著抑制大鼠晶状体醛糖还原酶(RLAR)活性(C50:23.99 μM。
T3676	Sesamol 3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚	Apoptosis; AMPK	Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Sesamol 是芝麻油的主要成分，具有抗氧化和抗肿瘤活性。它是一种自由基清除剂，在 DPPH 实验中，IC50为 5.95±0.56 μg/mL。
TN4754	Persicoside	Others	Others
	Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN3193	6-O-Vanilloylajugol	Others	Others
	6-O-Vanilloylajugol demonstrates scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
TN1207	2,4,7-Trihydroxy-9,10-dihydrophenanthrene	Others	Others
	2,4,7-Trihydroxy-9,10-dihydrophenanthrene showS the DPPH free radical scavenging activity with EC(50) from 8.8 to 55.9 microM.
TN3292	8-Prenyldaidzein	Others	Others
	8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging.
TN4000	Erythristemine	Others	Others
	(+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical.
TN2545	1-Hydroxypinoresinol 1-O-glucoside	ROS	Immunology/Inflammation
	(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively.
TMA0245	Hexacosyl (E)-ferulate	Others	Others
	Hexacosyl (E)-ferulate displays significant antioxidant activity in the DPPH assay (RC50 = 0.0976 mg/mL). It also might be a chemotaxonomic marker in the genus Echinops.
TN6414	Plantanone B
	Plantanone C exhibited moderate antioxidant activity against DPPH radical scavenging activity,with an IC50 value of 240. 2 μmol·L~(-1).
TN3879	Docosyl caffeate
	Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL.
TN1876	Lobetyolinin 党参炔苷宁	Others	Others
	Lobetyolinin exhibits DPPH radical scavenging activity.
TN4708	Olivil	Others	Others
	(-)-Olivil displays a higher antioxidative effect against the free radical DPPH.
TN5052	Ssioriside	Others	Others
	Ssioriside shows moderate antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.
TN4865	Putraflavone	Beta Amyloid; BACE	Neuroscience
	Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.
TN4617	N-trans-Feruloyl-3-methoxytyramine	Others	Others
	N-trans-Feruloyl-3-methoxytyramine shows significantly DPPH radical scavenging activities.
TN4445	Lobetyol	Others	Others
	Lobetyol shows significant antioxidant activity, it exhibits DPPH radical scavenging activity.
TN1802	Isoscoparin-2′′O-glucoside Isoscoparin-2''-Beta-D-glucopyranoside,异金雀花素-2”-O-吡喃葡萄糖苷	Others	Others
	Isoscoparin-2''-Beta-D-glucopyranoside shows prominent free radical scavenging activity in DPPH assay.
TN2129	Quercetin-3-o-rutinose	Others	Others
	Quercetin-3-o-rutinose has antioxidative activity, it exerts strong DPPH radical-scavenging activity.
TN3444	Aristolactam BII	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts its significant neuroprotective ef
TN4404	Ladanein	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities a
TN1896	Luteolin 5-O-glucoside 木犀草素-5-O-葡萄糖苷,藤黄菌素,Luteollin 5-glucoside	Others	Others
	Luteolin 5-O-α²-glucopyranoside has antioxidant activity, it can inhibit lipid peroxidation, and has DPPH radical-scavenging activity.
TN3902	Durantoside I	Others	Others
	Durantoside I has inhibitory activity on the growth of lettuce seedling. It also displays DPPH scavenging activity.
TN2240	Strictosidinic acid	Others	Others
	Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.
TN3381	Alnusdiol	Others	Others
	Alnusdiol exhibits the good scavenging activities against 2, 2-diphenyl-1-picryhydrazyl (DPPH), shows moderate anti-oxidant effects.
TN1689	Glabranine Glabranin,光甘草宁	Antifection	Microbiology/Virology
	Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereof could be used to stimulate hair growth. Glabranine exerts a dose-dependent inhibitory effect
TN1796	Brassicin 油菜,异鼠李素-7-O-Β-D-葡萄糖苷,Isorhamnetin 7-O-glucoside	Others	Others
	Isorhamnetin 7-O-glucoside has antioxidant activity, it showed the peroxynitrite and DPPH scavenging activities with IC50 values of 2.07 /- 0.17 and 13.3 microM, respectively.
TN4711	Onitin	Others	Others
	Onitin shows super-oxide and DPPH free radical scavenging effects.It also exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.
TN2798	20-Deoxocarnosol	Antifection; ROS	Immunology/Inflammation; Microbiology/Virology
	20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity.
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天然产物

Vanillylmandelic acid

synonym: 3-甲氧基-4-羟基扁桃酸,4-Hydroxy-3-methoxymandelic acid

synonym: Tetrahydroxystilbene,2,3',4,5'-tetrahydroxystilbene,trans-Oxyresveratrol,氧化白藜芦醇

Target: Tyrosinase, Autophagy, HSV

synonym: 灯心草菲酚,厄弗酚

Target: Caspase

Target: HSV, Others

Isobutylshikonin

Target: TLR, NF-κB

synonym: Nepetin-7-glucoside,假荆芥属苷

Target: Antioxidant

synonym: 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚

(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

synonym: (S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid,(S)-3-(4-羟苯基)乳酸

Target: AChE, Antioxidant

synonym: Ombuin-3beta-rutinoside,商陆素-3BETA-芸香糖苷

Target: Antibacterial

Epimedokoreanin B

Target: Apoptosis, Others, Antibacterial

Atherosperminine

Target: cAMP, Calcium Channel, Parasite, AChR

Hydroxytyrosol Acetate

synonym: 3,4-二羟基苯乙醇醋酸,HTy-Ac

Target: Antioxidant

Kaempferol-3-O-glucorhamnoside

synonym: Kaempferol 3-glucorhamnoside,百蕊草素I

Target: Antioxidant, p38 MAPK, NF-κB

(E)-Ferulic acid methyl ester

synonym: (E)-阿魏酸甲酯,Methyl (E)-ferulate,Methyl ferulate

Target: NO Synthase, JNK, TNF, Antifection, p38 MAPK, IL Receptor, COX

Target: P450, AChE

Calycosin-7-O-β-D-glucoside

synonym: Calycosin-7-O-beta-D-glucoside,calycosin-7-O-beta-D-glucopyranoside,毛蕊异黄酮苷

Target: Reactive Oxygen Species, MMP

Calceolarioside B

synonym: 木通苯乙醇苷 B,木通苯乙醇苷B,Desrhamnosyl isoacteoside,Nuomioside A

Target: Aromatase

synonym: 3,4-Methylenedioxyphenol,1,3-Benzodioxol-5-ol,芝麻酚

Target: Apoptosis, AMPK

6-O-Vanilloylajugol

2,4,7-Trihydroxy-9,10-dihydrophenanthrene

8-Prenyldaidzein

1-Hydroxypinoresinol 1-O-glucoside

Hexacosyl (E)-ferulate

Docosyl caffeate

synonym: 党参炔苷宁

Target: Beta Amyloid, BACE

N-trans-Feruloyl-3-methoxytyramine

Isoscoparin-2′′O-glucoside

synonym: Isoscoparin-2''-Beta-D-glucopyranoside,异金雀花素-2”-O-吡喃葡萄糖苷

Quercetin-3-o-rutinose

Aristolactam BII

Target: HIV Protease

Target: HCV Protease

Luteolin 5-O-glucoside

synonym: 木犀草素-5-O-葡萄糖苷,藤黄菌素,Luteollin 5-glucoside

Strictosidinic acid

synonym: Glabranin,光甘草宁

Target: Antifection

synonym: 油菜,异鼠李素-7-O-Β-D-葡萄糖苷,Isorhamnetin 7-O-glucoside

20-Deoxocarnosol

Target: Antifection, ROS

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