转化生长因子-β 家族 (Transforming Growth Factor-β family, TGF-βs)

Expression system: HEK293 Cells
Length: 197-308, Partial
Activity: Not Tested

Expression system: CHO Cells
Length: 279-390, Partial
Activity: Organoid Coculture、Cells

TGF beta 1 Protein, Rat Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.

GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.

Expression system: P. pastoris (Yeast)
Length: 197-308, Partial
Activity: Not Tested

Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate.

Expression system: HEK293 Cells
Length: 303-414, Partial
Activity: Cell Activity

Expression system: E. coli
Length: 189-303, Full Length of Mature Protein
Activity: ELISA

Expression system: E. coli
Length: 189-303, Full Length of Mature Protein
Activity: ELISA、SPR

Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.

GDNF Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number is Q07731-1.

Expression system: E. coli
Length: 78-211, Full Length of Mature Protein
Activity: Cell Activity

Expression system: HEK293 Cells
Length: 189-303, Full Length of Mature Protein
Activity: ELISA

SMAD5 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 79.9 kDa and the accession number is P97454.

Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P17246.

Expression system: E. coli
Length: 78-211, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 279-390, Partial
Activity: ELISA、Cells

Expression system: HEK293 Cells
Length: 311-426, Full Length of Mature Protein
Activity: Organoid Coculture、Cells

Expression system: HEK293 Cells
Length: 32-143, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 279-390, Partial
Activity: Cell Activity

Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma cells. Its mRNA expression on the left side of the developing embryo earned the name Lefty . The human orthologue was initially identified as Ebaf, Endometrial bleeding associated factor. Lefty contains the six cysteine residues that are conserved among TGF-β related proteins and that are necessary to form the cysteineknot structure. Its function in patterning left-right asymmetry of the developing organ systems such as the heart and lung is consistent in all vertebrate species examined. Lefty acts as an antagonist to Nodal signaling, potentially by competing for binding to a common receptor. It may play a role in endometrial bleeding.

Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.

Expression system: HEK293 Cells
Length: 32-143, Partial
Activity: Not Tested