Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T27026 | CJ-13,610
化合物CJ-13,610
|
179420-17-8 | 99.64% |
|
CJ-13,610 是一种具有口服活性的非氧化还原型 5-脂氧合酶 (5-LOX) 抑制剂。 CJ-13,610 抑制白三烯 B4 的生物合成并调节巨噬细胞中 IL-6 mRNA 的表达。 | ||||
T3090 | Abietic Acid
松香酸
|
514-10-3 | 92.6% |
|
Abietic Acid (Sylvic acid) 是从 Pimenta racemosavar. grissea 中提取出来的一种二萜,具有抗菌、抗增殖和抗肥胖的活性。它抑制脂氧合酶活性,可研究过敏性疾病。 | ||||
T10719 | CCT365623 hydrochloride
化合物 T10719
|
2126136-98-7 | 98% |
|
CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. | ||||
TN2688 | 2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone
2,3,4'-三羟基-3',5'-二甲氧基苯丙酮
|
33900-74-2 | 98% |
|
2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone 是一种天然产物,可从 Parinari hypochrysea (Chrysobalanaceae) 中提取得到。2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone 具有抗氧化活性且对脂... | ||||
T78820 | 5-LOX-IN-5
化合物 5-LOX-IN-5
|
98% |
|
|
5-LOX-IN-5(Compound 29)作为一种5-LOX抑制剂,拥有56 nM的半抑制浓度(IC50)。它主要被应用于神经退行性疾病的研究领域。 | ||||
T79158 | H15-LOX-2 inhibitor 1
化合物 h15-LOX-2 inhibitor 1
|
478040-08-3 | 98% |
|
h15-LOX-2 inhibitor 1(Comp 105)是一种针对人上皮细胞15-lipoxygenase-2 (h15-LOX-2)的抑制剂,表现出0.34 μM的IC50值。 | ||||
T79360 | COX-2/15-LOX-IN-2
化合物 COX-2/15-LOX-IN-2
|
98% |
|
|
COX-2/15-LOX-IN-2 作为一种效能高的双重抑制剂,对COX-2和15-LOX的IC50值分别为0.065 μM和1.86 μM,显示出显著的抗氧化活性。 | ||||
T79361 | COX-2/15-LOX-IN-3
化合物 COX-2/15-LOX-IN-3
|
98% |
|
|
COX-2/15-LOX-IN-3 (compound 5k) 为COX-2/15-LOX的一种双重抑制剂,具有分别为0.075 μM和1.97 μM的IC50值。该化合物能显著抑制LPS诱导的细胞产生促炎细胞因子(IL-6, ROS和NO),表明其具备显著的抗炎活性。 | ||||
T79362 | COX-2/15-LOX-IN-4
化合物 COX-2/15-LOX-IN-4
|
98% |
|
|
COX-2/15-LOX-IN-4(compound 5i)是一种针对COX-2和15-LOX的双重抑制剂,其IC50值分别为0.075 μM和1.97 μM。该化合物能有效地阻止LPS诱发的细胞内促炎细胞因子(IL-6, ROS)的产生,表现出明确的抗炎活性。 | ||||
T80651 | (-)-Bornyl ferulate
化合物 (-)-Bornyl ferulate
|
55511-07-4 | 98% |
|
(-)-Bornyl ferulate,作为5-脂氧合酶和COX抑制剂,其IC50值分别为10.4 μM和12.0 μM。 | ||||
T10151 | 5-Lipoxygenase-In-1
化合物 T10151
|
125235-15-6 | 98% |
|
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor. | ||||
T11196 | Enazadrem
依那扎群
|
107361-33-1 | 98% |
|
Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities. | ||||
TN1871 | Ligustroside
女贞甙
|
35897-92-8 | 98% |
|
Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustrosid... | ||||
TN5174 | Trichosanatine
化合物 TN5174
|
169626-16-8 | 98% |
|
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine... | ||||
TL0014 | Pinusolide
化合物 TL0014
|
31685-80-0 | 98% |
|
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a... | ||||
T10438 | AZD 4407
化合物 T10438
|
166882-70-8 | 98% |
|
AZD 4407 is a potent inhibitor of 5-lipoxygenase. | ||||
TN4783 | Picralinal
化合物 TN4783
|
20045-06-1 | 98% |
|
Picralinal has anti-inflammatory and analgesic effects. | ||||
T4571 | Balsalazide
巴柳氮
|
80573-04-2 | 98% |
|
Balsalazide (Balsalazido) 可通过调节IL-6/STAT3通路起抑癌作用,可用于治疗炎症性肠病。 | ||||
TN5020 | (+/-)-Sigmoidin A
化合物 TN5020
|
176046-04-1 | 98% |
|
Sigmoidin A has moderate antioxidant, antimicrobial and anti-inflammatory activity. | ||||
T67870 | DKI5
化合物DKI5
|
1101130-96-4 | 98% |
|
DKI5 ((E)-N'-benzylidenehydrazinecarbothiohydrazide) 是一种 LOX-1 抑制剂,IC50 值为 22.5 μM。DKI5 可能具有抗炎和抗氧化活性,在体外生物测定中显示出抗脂质过氧化活性。 |