MTP (Microsomal Triglyceride Transfer Protein) is an endoplasmic reticulum membrane protein primarily responsible for lipid transport and lipoprotein assembly. Expressed in liver, intestine, and adipocytes, MTP promotes lipoprotein maturation and secretion by transferring triglycerides and cholesterol esters to nascent lipoprotein particles. MTP regulates blood triglyceride and cholesterol levels, with its dysfunction implicated in various lipid metabolism disorders such as familial hypobeta-lipoproteinaemia and cardiovascular disease.

筛选首页信号通路代谢MTP

Dirlotapide
地洛他派, Slentrol, CP742033
T15006481658-94-0In house
Dirlotapide (CP742033) 是一种肠道选择性微粒体甘油三酯转移蛋白(MTP)抑制剂。它可以减轻糖尿病狗的体重。Dirlotapide 以剂量依赖性方式减少食物摄入量，可能是通过增加肽YY 释放到循环中。
MTP
- ¥ 2680
现货
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Lomitapide
洛美他派, BMS-201038, AEGR-733
T6267182431-12-5
Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂，体内试验的IC50值为8 nM。
MTP Others
- ¥ 247
现货
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Lomitapide Mesylate
甲磺酸洛美他派, BMS-201038 mesylate, AEGR-733 mesylate
T2545202914-84-9
Lomitapide Mesylate (BMS-201038 mesylate) 是一种高效MTP 蛋白抑制剂，其体外IC50值为8 nM。
MTP
- ¥ 253
现货
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Granotapide
T31992594842-13-4In house
Granotapide 是一种微粒体甘油三酯转移蛋白（MTP）抑制剂，治疗和而预防动脉硬化，冠状动脉疾病，代谢综合征，肥胖，糖尿病，糖尿病前期和高血压。
MTP
- ¥ 1480
现货
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KD-026
SLx-4090, SLx4090, SLx 4090, KD026
T27719913541-47-6
KD-026 (SLx 4090) 是具有口服活性的、肠细胞特异性的微粒体甘油三酯转移蛋白 (MTP)抑制剂，IC50为 8.0 nM。KD-026 (SLx 4090) 在糖尿病2型中有研究的价值。
MTP Others
- ¥ 653
现货
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PF-02575799
T16158863491-70-7
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
Adenosine Receptor MTP
- ¥ 12800
8-10周
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CP-346086
T39303186390-48-7
CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces plasma levels of cholesterol and triglycerides when administered in vivo.
MTP Others
询价
CP-346086 dihydrate
T386661262769-98-1
CP-346086 dihydrate is a potent and orally active inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM for both human and rodent MTP. This compound effectively lowers plasma cholesterol and triglyceride levels in vivo.
MTP Others
- ¥ 10600
6-8周
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Implitapide Racemate
T10504177277-99-5
Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
MTP Others
- ¥ 13900
8-10周
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CP-319340(free base)
T13418186390-35-2
CP-319340 free base is a inhibitor of microsomal triglyceride transfer protein (MTP) .
MTP Others
- ¥ 10600
6-8周
规格
数量
Implitapide
英普他派, AEGR 427
T15570177469-96-4
Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
CETP MTP
- 待询
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