Glyoxalase

S-Methylglutathione (S-Methyl glutathione) 是一种 S 取代的谷胱甘肽，是一种转移酶A催化的1-氯-2,4-二硝基苯偶联物的抑制剂，也是一种 XOCl 清除剂。S-Methylglutathione 抑制乙二醛酶 1 (glyoxalase 1) ，诱导水螅触手球形成。

BrBzGCp2 (p BrBzGSH(Cp)2) 是乙二醛酶 1 (GLO1) 抑制剂，具有抗肿瘤和神经保护活性，可以缓解焦虑，可用于研究神经系统疾病。

Glyoxalase I inhibitor (free base), a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.

N,S-Bis-Fmoc-Glutathione为一有效glyoxalase II抑制剂，其Ki值达0.32 mM。

Methyl gerfelin通过与三种关键细胞蛋白乙二醛酶 1 (GLO1)、固醇结合蛋白 2 (SCP2) 和富含谷氨酰胺的四肽重复蛋白 A (SGTA) 结合，抑制破骨细胞的分化。研究表明，Methyl gerfelin是一种与类黄酮相关的强效GLO1抑制剂。

N,S-Bis-Fmoc-Glutathione TFA 是一种高效的glyoxalase II抑制剂，其Ki值为0.75 μM，IC50值为2.5 μM。

Glyoxalase I inhibitor 4 是乙二醛酶 I (GLO1) 的有效抑制剂 (Ki: 10 nM)。

Glyoxalase I inhibitor 2 (compound 26) 是一种 glyoxalase I (GLO1) 的有效抑制剂 (IC50: 0.5 μM)。Glyoxalase I inhibitor 2 具有潜力进行抑郁和焦虑的研究。

4BAB (compound 29) 是一种乙二醛酶 I (GLO1) 的不可逆抑制剂，表现出抗癌活性。

Glyoxalase I inhibitor 1 是 glyoxalase I (GLO1) 的有效抑制剂 (IC50: 26 nM)。

Glyoxalase I inhibitor 5 (Compound 9h) is a potent inhibitor of glyoxalase I (Glo-I), with an IC50 value of 1.28 μM. This compound holds promise as an anticancer agent [1].

Glyoxalase I inhibitor 3 (compound 22g) 是一种有效的乙二醛酶 I (GLO1)抑制剂，IC50为 0.011 μM。Glyoxalase I inhibitor 3具有研究抑郁和焦虑的潜力。

Glyoxalase I inhibitor, a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.

COTC is a bacterial metabolite that has anticancer activity and inhibits glyoxalase in the presence of glutathione (GSH) and the proliferation of HeLa cells, as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.

TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].

HBPC-GSH，一种谷胱甘肽衍生物，作为糖醛酸酶(Glo)抑制剂，展示出对cGloII的IC50为0.6 μM，对cGloIII的IC50为1.6 μM，可用于抗疟疾研究。

Glyoxalase I inhibitor 7 (Compound 6) is a potent inhibitor of glyoxalase I (Glo-I) with an IC50 of 3.65 μM. It exhibits potential as an anticancer agent [1].

Glyoxalase I inhibitor 6 (Compound 9j) is an inhibitor of glyoxalase I (Glo-I) with an IC50 value of 1.13 μM. This compound shows potential as an anticancer agent, demonstrating low toxicity [1].