arap

Darapladib (SB-480848) 是脂蛋白相关磷脂酶A2 (Lp-PLA2) 抑制剂，IC50值为0.25 nM,可发挥心血管保护作用[1,3]。

Caraphenol A是一种天然产物，属于豆科锦鸡儿属，其产品编号为 TN5636，CAS号为 354553-35-8。Caraphenol A可用作对照参考。

Paraprost consists of 1-glutamic acid, alanine, and glycine. It was used in prostate hypertrophy drug therapy.

Darapladib-impurity 是 Darapladib 的杂质。Darapladib 对脂蛋白相关磷脂酶 A2 (Lp-PLA2)有抑制作用。

Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica.

Usmarapride free base (SUVN-D4010 free base) 是一种可透过血脑屏障且具有口服活性和选择性的 5-HT4 受体部分激动剂，可提高可溶性淀粉样蛋白前体蛋白 α 的水平，可用于研究阿尔茨海默病。

Parapenzolate Free Base is a safe and effective anticholinergic drug possessing antisecretory and antimotility properties and prolonged duration of action. Clinical investigation has shown that after an oral dose of the drug there was inhibition of both basal and histamine-stimulated acid outputs.

Parapenzolate bromide 是一种口服具有活力的 mAChR 拮抗剂。Parapenzolate bromide 是一种抗胆碱能剂，也是一种解痉挛剂。

Usmarapride (SUVN-D4010) 是一种选择性的、口服具有活力的、有效的、具有血脑屏障通透性的 5-HT4 受体部分激动剂，其 EC50 值为 44 nM。Usmarapride (SUVN-D4010) 能够用于研究阿尔茨海默病相关认知缺陷。

Fludarabine Phosphate (NSC 312887 Phosphate) 是一种腺苷和脱氧腺苷类似物，与 dATP 竞争，并入到 DNA，可以抑制 DNA 聚合酶 α、核糖核苷酸还原酶和 DNA 引发酶，从而中断 DNA 合成并抑制肿瘤细胞生长。

Rezafungin (SP-3025) 是一种长效的广谱棘皮菌素，对念珠菌、曲霉和肺孢子菌具有强效抗真菌活性。

YARA peptide，这是一种细胞穿透肽，同时也是MK2的抑制剂。在体外皮肤培养模型中，负载有YARA的纳米颗粒可以降低炎症细胞因子 (IL-1β, IL-6和TNF-α) 的水平。YARA peptide 被视为特应性皮炎 (AD) 研究的潜在工具。

AMARA peptide (TFA) is a substrate for salt-induced kinase (SIK) and adenosine activated protein kinase (AMPK).

EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also exhibits high potency in selectively inhibiting the proliferation of BRAF (V600E)-dependent cell lines (A375 and Colo205) and cellular Erk phosporylation, with superior activity to Vemurafenib. EBI-907, displaying potent activity against a number of important oncogenic kinases including BRK, FGFR1, c-Kit, and PDGFRb.

AMARA peptide is a minimal substrate for several members of the protein kinase family, including SIK and AMPK, and contains the phosphorylation site for AMP-activated Protein Kinase (AMPK).

Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33 079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg mL, 1 μg mL, 8 μg mL, 2

AMARA peptide acetate(163560-19-8 free base) 是 SIK 和 AMPK 的底物。AMARA 肽是蛋白激酶家族几个成员的底物。它由 AMP 激活的蛋白激酶 (AMPK) 的磷酸化位点组成。