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Cat. No. |
Product Name |
Target |
Signaling Pathways |
T39823L
|
Apelin-12 acetate
|
Apelin receptor;
p38 MAPK;
JNK |
GPCR/G Protein;
MAPK |
|
Apelin-12 acetate 对 APJ 受体具有高亲和力。 Apelin-12 acetate 抑制凋亡相关 MAPKs 家族的 JNK 和 p38 MAPK 信号通路,从而为神经元提供保护。 |
T39823
|
Apelin-12
|
|
|
|
Apelin-12 is a highly potent C-terminal fragment of a polypeptide that exhibits a strong affinity towards the orphan receptor APJ. It plays a role in maintaining body fluid balance and regulating feeding control in the central nervous system. Additionally, Apelin-12 functions as an inhibitor of HIV-1 entry through the APJ receptor and demonstrates neuroprotective properties. |