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Search Results for " glp1 "

Targets Recommended: Glucagon Receptor

26

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP2252	GLP-1 (9-36) amide	Glucagon Receptor	GPCR/G Protein
	GLP-1(9-36)amide 是胰高血糖素样肽-1 (7-36) amide 的主要代谢产物，对人胰腺 GLP-1受体具有拮抗作用。
TP1376	GLP-1(7-37) acetate(106612-94-6 free base) GLP-1(7-37) acetate	Others; Glucagon Receptor	GPCR/G Protein; Others
	GLP-1(7-37) acetate 是肠道胰岛素激素，能够促进葡萄糖诱导的胰岛素分泌。
T76350	[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
	[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH 是一种黄体激素释放激素 (LHRH) 类似物，可作为 GnRH 受体拮抗剂。
TP1306	GLP-1(7-37)
	GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.
T11408	Orforglipron LY3502970,GLP-1 receptor agonist 1	Glucagon Receptor	GPCR/G Protein
	Orforglipron (LY3502970; GLP-1 receptor agonist 1) 是一种可口服的胰高血糖素样肽 (GLP-1) 受体激动剂，可用于研究成人肥胖和1型糖尿病。
T37890L	GLP-1(28-36)amide acetate GLP-1(28-36)amide acetate(1225021-13-5 Free base)	Antioxidant; Glucagon Receptor	GPCR/G Protein; oxidation-reduction
	GLP-1(28-36)amide acetate 抑制线粒体通透性转变，具有抗氧化、抗糖尿病和心脏保护活性。
T9579L	GLP-1 receptor agonist 9 citrate GLP-1 receptor agonist 9 citrate (2401892-71-3 Free base)	Glucagon Receptor	GPCR/G Protein
	GLP-1 receptor agonist 9 citrate 是 GLP-1 的激动剂。
T36380	GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
	GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and truncated GLP-1 (7-36) amide , in pancreatic tissue compared to wild-type mice.2References1. Schjoldager, B.T., Mortensen, P.E., Christiansen, J., et al. GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans...
T37891	GLP-1(32-36)amide
	GLP-1(32-36)amide is a pentapeptide compound derived from the C terminus of the glucoregulatory hormone GLP-1. This compound has shown potential in inhibiting weight gain and regulating glucose metabolism in diabetic mice[1][2].
T11407	GLP-1 receptor agonist 2	Others	Others
	GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist.
T37890	GLP-1(28-36)amide
	GLP-1(28-36)amide, a C-terminal nonapeptide derived from the cleavage of GLP-1 by neutral endopeptidase (NEP), is a significant product. It functions as an antioxidant and primarily targets the mitochondrion, where it effectively inhibits mitochondrial permeability transition (MPT). This compound exhibits anti-diabetic properties and demonstrates cardioprotection effects[1].
T11404	GLP-1 receptor agonist 3	Others	Others
	GLP-1 receptor agonist 3 is a GLP-1 receptor agonist,Example 4A-1, has EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.
TP1316	GLP-1 moiety from Dulaglutide
	GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist.
T37891L	GLP-1(32-36)amide acetate GLP-1(32-36)amide 醋酸盐,GLP-1(32-36)amide acetate(1417302-71-6 Free base)	Others	Others
	GLP-1(32-36)amide acetate 是一种五肽，衍生自糖调节激素 GLP-1 的 C 末端。GLP-1(32-36)amide acetate 可抑制糖尿病小鼠的体重增加并调节全身葡萄糖代谢。
T37892	GLP-1(7-36), amide TFA
	GLP-1(7-36), amide TFA is a prominent intestinal hormone known to stimulate glucose-induced insulin secretion from β cells[1].
T11405	GLP-1 receptor agonist 4	Others	Others
	GLP-1 receptor agonist 4 is a glucagon-like peptide-1 receptor (GLP-1R) agonist , has an EC50 of 64.5 nM. GLP-1 receptor agonist 4 can be used in the research for treatment of diabetes.
T9579	GLP-1 receptor agonist 9	Glucagon Receptor	GPCR/G Protein
	1H-Benzimidazole-6-carboxylic acid 是GLP-1 receptor 激动剂。
TP1141	GLP-1(7-36), amide acetate GLP-1(7-36) Acetate,Human GLP-1-(7-36)-amide Acetate
	GLP-1(7-36) Acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
T3984	GLP-1(7-36), amide MKC 253,胰高血糖素样肽-1,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide	Glucagon Receptor	GPCR/G Protein
	GLP-1(7-36), amide (MKC 253) 是一种生理性肠降血糖素，能够刺激胰岛素分泌。
T8748	Exendin-4 acetate	Glucagon Receptor	GPCR/G Protein
	Exendin-4 acetate 是一种长效的 glucagon-likepeptide-1 受体激动剂(IC50:3.22 nM)，是一种由39个氨基酸组成的多肽。。
TQ0124	BETP	Glucagon Receptor	GPCR/G Protein
	BETP 是胰高血糖素样肽 (GLP-1) 受体激动剂，能够抑制人和大鼠的GLP-1受体，其EC50值分别为 0.66 μM 和 0.755 μM。
T3967	Exendin-4 艾塞那肽,Exenatide,Exenatide Acetate	Glucagon Receptor	GPCR/G Protein
	Exendin-4 (Exenatide) 是一种长效的 glucagon-likepeptide-1 受体激动剂(IC50: 3.22 nM)，是一种由 39 个氨基酸组成的多肽。
TP1103	Cotadutide acetate MEDI0382 acetate,Cotadutide acetate (1686108-82-6 Free base)	Glucagon Receptor	GPCR/G Protein
	Cotadutide acetate (MEDI0382 acetate) 是一种有效的胰高血糖素样肽-1 (GLP-1) 和胰高血糖素受体肽双重激动剂，EC50 分别为 6.9 pM 和 10.2 pM。
T13218	TT-OAD2	Others	Others
	TT-OAD2 is a non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (EC50: 5 nM), with the potential for diabetes treatment.
T13091	Taspoglutide R1583,BIM51077,ITM077	Others	Others
	Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes
T11406	TT-OAD2 free base	Others	Others
	TT-OAD2 free base has the potential for diabetes treatment. TT-OAD2 free base is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM.

化合物

GLP-1 (9-36) amide

Cat.No: TP2252

Target: Glucagon Receptor

GLP-1(7-37) acetate(106612-94-6 free base)

Cat.No: TP1376

Synonym: GLP-1(7-37) acetate

Target: Others, Glucagon Receptor

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH

Cat.No: T76350

Cat.No: TP1306

Cat.No: T11408

Synonym: LY3502970,GLP-1 receptor agonist 1

Target: Glucagon Receptor

GLP-1(28-36)amide acetate

Cat.No: T37890L

Synonym: GLP-1(28-36)amide acetate(1225021-13-5 Free base)

Target: Antioxidant, Glucagon Receptor

GLP-1 receptor agonist 9 citrate

Cat.No: T9579L

Synonym: GLP-1 receptor agonist 9 citrate (2401892-71-3 Free base)

Target: Glucagon Receptor

GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)

Cat.No: T36380

GLP-1(32-36)amide

Cat.No: T37891

GLP-1 receptor agonist 2

Cat.No: T11407

Target: Others

GLP-1(28-36)amide

Cat.No: T37890

GLP-1 receptor agonist 3

Cat.No: T11404

Target: Others

GLP-1 moiety from Dulaglutide

Cat.No: TP1316

GLP-1(32-36)amide acetate

Cat.No: T37891L

Synonym: GLP-1(32-36)amide 醋酸盐,GLP-1(32-36)amide acetate(1417302-71-6 Free base)

Target: Others

GLP-1(7-36), amide TFA

Cat.No: T37892

GLP-1 receptor agonist 4

Cat.No: T11405

Target: Others

GLP-1 receptor agonist 9

Cat.No: T9579

Target: Glucagon Receptor

GLP-1(7-36), amide acetate

Cat.No: TP1141

Synonym: GLP-1(7-36) Acetate,Human GLP-1-(7-36)-amide Acetate

GLP-1(7-36), amide

Cat.No: T3984

Synonym: MKC 253,胰高血糖素样肽-1,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide

Target: Glucagon Receptor

Exendin-4 acetate

Cat.No: T8748

Target: Glucagon Receptor

Cat.No: TQ0124

Target: Glucagon Receptor

Cat.No: T3967

Synonym: 艾塞那肽,Exenatide,Exenatide Acetate

Target: Glucagon Receptor

Cotadutide acetate

Cat.No: TP1103

Synonym: MEDI0382 acetate,Cotadutide acetate (1686108-82-6 Free base)

Target: Glucagon Receptor

Cat.No: T13218

Target: Others

Cat.No: T13091

Synonym: R1583,BIM51077,ITM077

Target: Others

TT-OAD2 free base

Cat.No: T11406

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00742	GCG Protein, Human, Recombinant (His) Glicentin,GRPP,GLP-2,Glucagon-Like Peptide 1	Human	HEK293 Cells
	Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin....
TMPY-06864	GLP1R Protein, Human, Recombinant (His & Avi) glucagon-like peptide 1 receptor	Human	HEK293 Cells
	Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like p...
TMPH-01385	GLP1R Protein, Human, Recombinant (His)	Human	HEK293 Cells
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-03301	GLP1R Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.1 kDa and the accession number is P32301.
TMPH-02676	GLP1R Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is O35659.
TMPH-01384	GLP1R Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-03302	GLP1R Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	GLP1R Protein, Rat, Recombinant (His) is expressed in Yeast.

重组蛋白

GCG Protein, Human, Recombinant (His)

Cat.No: TMPJ-00742

Species: Human

Expression System: HEK293 Cells

GLP1R Protein, Human, Recombinant (His & Avi)

Cat.No: TMPY-06864

Species: Human

Expression System: HEK293 Cells

GLP1R Protein, Human, Recombinant (His)

Cat.No: TMPH-01385

Species: Human

Expression System: HEK293 Cells

GLP1R Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03301

Species: Rat

Expression System: E. coli

GLP1R Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02676

Species: Mouse

Expression System: E. coli

GLP1R Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01384

Species: Human

Expression System: E. coli

GLP1R Protein, Rat, Recombinant (His)

Cat.No: TMPH-03302

Species: Rat

Expression System: P. pastoris (Yeast)

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