Dvd-445 has good anti-cancer effect.Dvd-445 is an effective peptide covalent thioredoxin reductase 1 (TrxR1) inhibitor with IC50 value of 0.60 mol L M.
D-4418 is a PDE4 inhibitor. It has been in development as a novel anti-inflammatory therapy with asthma and chronic obstructive pulmonary disease being primary indications.