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Maximin 1，源自Bombina maxima皮肤分泌物的抗菌肽，具备针对肿瘤细胞的细胞毒性及杀精能力。

Maximin 15为源自蟾蜍大脑的抗菌肽，具有针对金黄色葡萄球菌、大肠杆菌和枯草芽孢杆菌的活性，其最小抑菌浓度(MIC)值依次为9.4, 18.8, 75 μg mL。

Autogramin-1可以有效抑制由饥饿诱导和 Rapamycin (通过抑制 mTORC1) 诱导的自噬 ，IC50分别为 0.17 μM 和 0.44 μM。

BLM-IN-1 is an effective Bloom syndrome protein (BLM) inhibitor (KD: 1.81 μM; IC50: 0.95 μM). It induces DNA damage response, apoptosis and proliferation arrest in cancer cells

Dynasore (Dynamin Inhibitor I) 是一种可渗透细胞的化学物质，可逆且非竞争性地抑制 dynamin 1 2 的 GTPase 活性。 它还抑制线粒体动力蛋白 Drp1，对其他小 GTPase 没有影响。

UGM-IN-1抑制UGM的活性，从而阻碍C. glutamicum的生长。

HDM-IN-1 (Compound A4) 是一种真菌组蛋白去甲基化酶（HDM）抑制剂，能够抑制Cryptococcus neoformans和Candida auris中的H3K27me3，IC50值分别为134 nM和12 nM。此化合物通过抑制生物膜和荚膜的形成，对Cryptococcus neoformans和Candida auris显示出抗菌特性，MIC80为0.5-2 μg mL。在ICR小鼠模型中，HDM-IN-1表现出抗真菌活性。

MIN-117, a SSRI 5-HT receptor antagonist, is potentially used for the treatment of depression.

MNK/PIM-IN-1 is a novel dual inhibitor targeting both MNK and PIM pathways, characterized by its favorable pharmacokinetic profile.

PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC 50 = 61 nM; pS6, EC 50 = 71 nM).

Bim-IN-1 是一种 Bim 表达的有效抑制剂，毒性较低。Bim-IN-1 可以减少 Bim 的表达水平，且几乎不会抑制蛋白激酶 A。

ATM-IN-1 是 ATM 的有效抑制剂。其中 ATM 主要位于细胞核和微粒体中，参与细胞周期进程和细胞周期检查点对 DNA 损伤的反应。ATM-IN-1 对癌症和神经疾病表现出研究潜力。

MK1496 is a n orally bioavailable Polo-like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor MK1496 selectively inhibits Plk1, inducing selective G2 M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. Plk1, named after the polo gene of Drosophila melanogaster, is a serine threonine protein kinase involved in regulating mitotic spindle function in a non-ATP competitive manner. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

Pim-IN-14j is a potent, highly selective, and orally bioavailable inhibitor of PIM-1 kinases.

Notum-IN-1 是一种口服有效的、选择性、脑渗透性的Notum 抑制剂。Notum-IN-1 在小鼠体内阻断Wnt 信号。

ASM-IN-1是一种高效的口服活性ASM抑制剂，具有1.5 µM的IC50值。该化合物在减少主动脉弓及主动脉的脂质斑块方面表现出效果，并能够降低血浆中的神经酰胺以及Ox-LDL水平。ASM-IN-1展现了抗动脉粥样硬化与抗炎的活性。

Ovalbumin (154-159)为卵清蛋白片段，同时作为一种有效的血管紧张素转换酶 (ACE) 抑制剂，适用于高血压研究。

DMA-IN-1是一种DNA腺嘌呤甲基转移酶抑制剂，具有48 μM的IC50值。同时，它能够抑制Caulobacter的生长，其MIC为35 μM。

RET V804M-IN-1 (RETV804M kinase inhibitor) 是一种 wt-RET 选择性的RETV804M 激酶抑制剂，其IC50=20 nM。

Methylcobalamin-13C-d3 是 Methylcobalamin 的 13C 和氘代化合物。Methylcobalamin 的 CAS 号为 13422-55-4。Methylcobalamin 是维生素B12的一种形式,可直接参与同型半胱氨酸代谢。

Thymin-1-yl acetic acid is a PNA-related Derivative; PNA monomer.

Sarpogrelate hydrochloride (MCI-9042) 是一种选择性5-HT2R 拮抗剂，可用于研究与血栓形成有关的血管疾病，对 5-HT2A、5-HT2B 和 5-HT2C 受体的pKi 值分别为 8.52、6.57 和 7.43。

L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 μM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine is an enantiomer of Eflornithine.

SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.IC50 value: 9.0(pKi) [1]Target: 5-HT2C antagonistin vitro: SB 242084 had over 100-fold selectivity over a range of other 5-HT, dopamine and adrenergic receptors. In studies of 5-HT-stimulated phosphatidylinositol hydrolysis using SH-SY5Y cells stably expressing the cloned human 5-HT2C receptor, SB 242084 acted as an antagonist with a pKb of 9.3, which closely resembled its corresponding receptor binding affinity [1].in vivo: SB 242084 potently inhibited m-chlorophenylpiperazine (mCPP, 7 mgkg i.p. 20 min pre-test)-induced hypolocomotion in rats, a model of in vivo central 5-HT2C receptor function, with an ID50 of 0.11 mg kg i.p., and 2.0 mg kg p.o. SB 242084 (0.1-1 mg kg i.p.) exhibited an anxiolytic-like profile in the rat social interaction test, increasing time spent in social interaction, but having no effect on locomotion. SB 242084 (0.1-1 mg kg i.p.) also markedly increased punished responding in a rat Geller-Seifter conflict test of anxiety, but had no consistent effect on unpunished responding [1].