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FOXO1

FOXO1

Forkhead box protein O1 (FOXO1) also known as forkhead in rhabdomyosarcoma (FKHR) is a protein that in humans is encoded by the FOXO1 gene. FOXO1 is a transcription factor that plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. It is primarily regulated through phosphorylation on multiple residues; its transcriptional activity is dependent on its phosphorylation state.
Cat. No. Product Name CAS No. Purity Chemical Structure
TN4390 Kihadanin B
化合物 TN4390
73793-68-7 98%
Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
T6762 AS1842856
化合物AS1842856
836620-48-5 98%
AS1842856 是一种特异性的Foxo1抑制剂,IC50为 30 nM。它抑制自噬,直接与 FoxO1 结合而降低 FoxO1 的活性。
Kihadanin B
TN4390
Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
AS1842856
T6762
AS1842856 是一种特异性的Foxo1抑制剂,IC50为 30 nM。它抑制自噬,直接与 FoxO1 结合而降低 FoxO1 的活性。
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