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Search Results for " thioredoxin "

Targets Recommended: Thioredoxin Others

33

抑制剂 & 化合物

1

天然产物

27

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1604L	Thioredoxin reductase peptide acetate Thioredoxin reductase peptide acetate(950890-23-0 free base)	Others	Others
	Thioredoxin reductase peptide acetate(950890-23-0 free base) 对应于硫氧还蛋白还原酶 (TrxR) 中的 53–67 位残基，用于硫氧还蛋白还原酶研究。哺乳动物硫氧还蛋白还原酶 (TR) 催化硫氧还蛋白 (Trx) 的氧化还原活性二硫键的还原，并且在结构和谷胱甘肽还原酶的作用机制，除了 C 末端的 16 个氨基酸延伸部分含有一个罕见的连位硒硫键。
TP1604	Thioredoxin reductase peptide
	Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfide bond of thioredoxin (Trx) and is
TP1375	Thioredoxin reductase peptide TFA
	Thioredoxin reductase peptide TFA corresponds to residues 53-67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research..
T13230	TXNIP-IN-1	Others	Others
	TXNIP-IN-1 是硫氧还蛋白-硫氧还蛋白相互作用蛋白复合物抑制剂。它在 TXNIP-TRX 复合物相关代谢紊乱的糖尿病、心血管疾病或炎症疾病方面有研究的价值。
T5481	TRi-1	Others	Others
	TRi-1 是不可逆的胞质硫氧还蛋白还原酶1 的特异性抑制剂(IC50:12 nM)。它有抗肿瘤作用，且线粒体毒性很小。
T20168	Aurothiomalate sodium 金硫丁二钠,Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Others
	Aurothiomalate sodium (Miochrysin) 是一种选择性的致癌 PKCι信号传导抑制剂，可抑制肿瘤细胞增殖。它是一种硫氧还蛋白还原酶 (TrxR) 抑制剂，也是一种抗风湿剂。
T9118	KEA1-97	Apoptosis; Others; Caspase	Apoptosis; Others; Proteases/Proteasome
	KEA1-97 是一种选择性硫氧还蛋白-半胱天冬酶 3相互作用干扰剂，IC50为10 μM。它在不影响硫氧还蛋白活性的情况下, 破坏硫氧还蛋白与 caspase 3 的相互作用，激活半胱天冬酶，诱导细胞凋亡。
T39664	Ethaselen BBSKE
	Ethaselen (BBSKE), a selective thioredoxin reductase (TrxR) inhibitor, is orally active with IC50s of 0.5 and 0.35 μM for wild-type human TrxR1 and rat TrxR1, respectively. Ethaselen specifically binds to the unique selenocysteine-cysteine redox pair located in the C-terminal active site of mammalian TrxR1. As an organoselenium compound, it demonstrates potent antitumor activity against non-small cell lung cancer (NSCLC) by targeting TrxR.
T4414	Eprenetapopt APR-246,PRIMA-1Met	Apoptosis; Others; Ferroptosis; p53; Autophagy	Apoptosis; Autophagy; Others
	Eprenetapopt (PRIMA-1Met) 是一种在 TP53突变细胞中恢复野生型 p53功能的小分子，可引发肿瘤细胞凋亡，还抑制硒蛋白硫氧还蛋白还原酶 1。
T60446	LCS3	Apoptosis; Glutathione reductase	Apoptosis; oxidation-reduction
	LCS3是一种可逆和非竞争性的谷胱甘肽二硫化物还原酶（GSR）和硫氧还蛋白还原酶1（TXNRD1）的协同抑制剂，IC50分别为3.3μM 和3.8μM。LCS3具有抗肿瘤活性，可诱导细胞凋亡，可用于研究肺腺癌（LUAD）。
T2283	PX-12 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12	Thioredoxin	Metabolism
	PX-12 (PX12) 是一种可逆的硫氧还蛋白-1(Trx-1)抑制剂，能够抑制 MCF-7 细胞(IC50:1.9 μM)和HT-29 细胞(IC50:2.9 μM)的生长。
T24593	PAO-PDT PAO PDT
	PAO-PDT is a highly selective thioredoxin reductase inhibitor.
T23166	PMX 464	Others	Others
	inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system
T70131	TPP2a bromide
	TPP2a is a mitochondrial thioredoxin reductase (TrxR) inhibitor.
T33413	Mito-TRFS MitoTRFS
	Mito-TRFS is the first off-on probe for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells.
T29018	TrxR inhibitor D9 D9,TrxR-IN-D9
	TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).
T28906	T6603185 T-6603185,T 6603185
	T6603185 is a novel inhibitor of peroxiredoxin (Prx) and thioredoxin (Trx) systems.
T34922	TRFS-red TRFSred
	TRFS-red is the first red emission off-on probe for thioredoxin reductase.
T40946	Seph-PAO
	Seph-PAO, a modified form of polyalphaolefin (PAO) compound, is created by coupling a sepharose fluorophore. Its primary application lies in the detection of thioredoxin reductase (TrxR).
T39048	Sel-green
	Sel-green is a selective selenol fluorescent probe used for quantifying the selenocysteine (Sec) content in the selenoenzyme thioredoxin reductase, as well as imaging endogenous Sec in live HepG2 cells.
T11130	DVD-445	Others	Others
	Dvd-445 has good anti-cancer effect.Dvd-445 is an effective peptide covalent thioredoxin reductase 1 (TrxR1) inhibitor with IC50 value of 0.60 mol/L M.
T39915	Trx-red Trx-red,NBL-SS perchlorate
	Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derived from the nile blue fluorophore. It is specifically designed for imaging thioredoxin (Trx) in live cells and in vivo, with excitation and emission wavelengths of 615 nm and 661 nm, respectively.
T75351	TP-TRFS
	TP-TRFS 是高度选择性的一个硫氧还蛋白还原酶 (TrxR) 双光子荧光探针。
T62021	TrxR-IN-2
	TrxR-IN-2 是潜在的硫氧还蛋白还原酶（TrxR）抑制剂。TrxR-IN-2在治疗耐药性肝细胞癌中有研究价值。
T79198	S-Gem	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	S-Gem为TrxR依赖性前药，是Gemcitabine的衍生物，能够被TrxR选择性激活。与Gemcitabine相比，S-Gem展现出较低的细胞毒性。
T36399	PAO-Nap
	PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1].
T73825	TRFS-green
	TRFS-green 是用于检测活细胞中、硫氧还蛋白还原酶 (TrxR)、且具有高度选择性的、off−on 荧光探针。TRFS-green 的 λmax 是 377 nm。
T61647	TrxR-IN-5
	TrxR-IN-5 (compound 4f) is an efficacious inhibitor of TrxR (thioredoxin reductase) with an IC50 of 0.16 μM. By elevating the levels of reactive oxygen species (ROS), TrxR-IN-5 fosters robust antiproliferative impacts. Additionally, TrxR-IN-5 demonstrates pronounced effects against cancer proliferation and metastasis [1].
T62294	SRI-37330 hydrochloride
	SRI-37330 hydrochloride 是一种口服具有活力的硫氧还蛋白相互作用蛋白（TXNIP）抑制剂。SRI-37330 hydrochloride 对胰高血糖素分泌和功能具有抑制作用，可以降低肝脏葡萄糖的产生，逆转肝脏脂肪变性。SRI-37330 hydrochloride 能够用于研究 2 型糖尿病。
T78158	MitoCur-1	Others	Others
	MitoCur-1为一种姜黄素类似物，作为线粒体抗氧化硫氧还蛋白还原酶2（TrxR2）抑制剂，展现亲电性与线粒体靶向特性。该化合物能特异性诱导活性氧（ROS）生成，表现出抗肿瘤活性。
T73512	ZC0109
	ZC0109 是 IDO1和硫氧还蛋白还原酶 1 (TrxR1) 的双抑制剂，IC50分别为 50 nM 和 3.0 μM。ZC0109 诱导活性氧 (ROS) 积累，使细胞周期阻滞于 G1/S 期，导致癌细胞凋亡 (apoptosis)。
T35811	CAY10410
	CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. 15-deoxy-δ12,14-PGJ2 has been shown to be a potent ligand for PPARγ. Metabolism of the cyclopentenone prostaglandins PGA2, PGJ2, and δ12-PGJ2 occurs via glutathione addition across the α,β unsaturated enone. CAY10410 was designed as an analog of the PPARγ-binding prostaglandins which could not undergo this conjugation reactio...
T83871	Ferroptocide
	Ferroptocide是一种抑制剂，可抑制硫氧还蛋白(Trx)活性，并且是pleuromutilin的衍生物。在20 µM的浓度下，Ferroptocide能够抑制ES-2卵巢癌细胞中的Trx活性，并对ES-2细胞具有细胞毒性(IC50 = 1.6 µM)。5 µM的Ferroptocide能够诱导ES-2细胞发生铁死亡，这一效应可以通过铁螯合剂去铁胺(DFO)、抗氧化剂Trolox或铁死亡抑制剂ferrostatin-1来阻断。在使用免疫完整但非免疫缺陷小鼠的4T1小鼠乳腺癌模型中，每周两次以50 mg/kg剂量给药时，Ferroptocide能够减少肿瘤体积。

化合物

Thioredoxin reductase peptide acetate

Cat.No: TP1604L

Synonym: Thioredoxin reductase peptide acetate(950890-23-0 free base)

Target: Others

Thioredoxin reductase peptide

Cat.No: TP1604

Thioredoxin reductase peptide TFA

Cat.No: TP1375

Cat.No: T13230

Target: Others

Cat.No: T5481

Target: Others

Aurothiomalate sodium

Cat.No: T20168

Synonym: 金硫丁二钠,Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate

Target: Others, PKC

Cat.No: T9118

Target: Apoptosis, Others, Caspase

Cat.No: T39664

Synonym: BBSKE

Cat.No: T4414

Synonym: APR-246,PRIMA-1Met

Target: Apoptosis, Others, Ferroptosis, p53, Autophagy

Cat.No: T60446

Target: Apoptosis, Glutathione reductase

Cat.No: T2283

Synonym: 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12

Target: Thioredoxin

Cat.No: T24593

Synonym: PAO PDT

Cat.No: T23166

Target: Others

Cat.No: T70131

Cat.No: T33413

Synonym: MitoTRFS

TrxR inhibitor D9

Cat.No: T29018

Synonym: D9,TrxR-IN-D9

Cat.No: T28906

Synonym: T-6603185,T 6603185

Cat.No: T34922

Synonym: TRFSred

Cat.No: T40946

Cat.No: T39048

Cat.No: T11130

Target: Others

Cat.No: T39915

Synonym: Trx-red,NBL-SS perchlorate

Cat.No: T75351

Cat.No: T62021

Cat.No: T79198

Target: Nucleoside Antimetabolite/Analog

Cat.No: T36399

Cat.No: T73825

Cat.No: T61647

SRI-37330 hydrochloride

Cat.No: T62294

Cat.No: T78158

Target: Others

Cat.No: T73512

Cat.No: T35811

Cat.No: T83871

Cat. No.	Product Name	Target	Signaling Pathways
T5372	L-SelenoMethionine L-(+)-Selenomethionine,L-硒代蛋氨酸	Apoptosis; Amino Acids and Derivatives; Endogenous Metabolite	Apoptosis; Metabolism
	L-SelenoMethionine (L-(+)-Selenomethionine) 是 Selenomethionine 的 L-异构体，是硒的主要天然食物形式。它是一种癌症化学预防剂，可以增加谷胱甘肽过氧化物酶的表达，还可以通过饮食补充降低癌症的发生率并诱导癌细胞凋亡。

天然产物

L-SelenoMethionine

Cat.No: T5372

Synonym: L-(+)-Selenomethionine,L-硒代蛋氨酸

Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00382	Thioredoxin/TRX Protein, Mouse, Recombinant Txn,Txn1,thioredoxin	Mouse	E. coli
	Thioredoxin/TRX Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.7 kDa and the accession number is P10639.
TMPY-02250	Thioredoxin/TRX Protein, Human, Recombinant thioredoxin,TRDX,DKFZp686B1993,MGC61975,TXN,TRX1,RP...	Human	E. coli
	Thioredoxin/TRX Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.7 kDa and the accession number is P10599.
TMPY-02084	Thioredoxin 2/TRX2 Protein, Human, Recombinant (His) MT-TRX,RP5-1119A7. 13-005,TRX2,MTRX,thioredoxin 2	Human	E. coli
	Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small ...
TMPY-02723	TXNL4B Protein, Human, Recombinant (His) DLP,Dim2,thioredoxin-like 4B	Human	E. coli
	Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. Despite their biological and structural similarities, Dim1 and Dim2 proteins differ in many aspects. Dim1 bears distinctive st...
TMPJ-01098	PRDX4 Protein, Human, Recombinant (His) Prx-IV,Thioredoxin-Dependent Peroxide Reductase A03...	Human	E. coli
	Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-...
TMPY-02572	TXNDC17 Protein, Human, Recombinant thioredoxin domain containing 17,TXNL5,TRP14	Human	E. coli
	Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member of the thioredoxin (Trx)-fold protein family that lacks activity with classical Trx1 substrates. TXNDC17 is a novel 14-kDa disulfide reductase of the TXN (thioredoxin) family. TXNDC17 is involved in the TNF (tumor necrosis factor) signaling pathway. Moreover, TXNDC17 plays an important role in Taxol resistance via enha...
TMPJ-01404	TMX2 Protein, Human, Recombinant (His) Cell proliferation-inducing gene 26 protein,TMX2,Thiored...	Human	E. coli
	TMX2 is a single-pass type I membrane protein and contains 1 thioredoxin domain. Thioredoxin plays an important role in various cellular processes through redox regulation. The Molecular Cloning and characterization of one member of the thioredoxin superfamily, designated as TMX2.The TMX2 cDNA consists of 1644 nucleotides and contains an open reading frame encoding a protein of 372 amino acids with a predicted molecular mass of 42.5 kDa and an isoelectric point of 8.94. The TMX2 protein may pos...
TMPY-05058	TMX1 Protein, Human, Recombinant (mFc) thioredoxin-related transmembrane protein 1,PDIA11,...	Human	HEK293 Cells
	As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways.
TMPY-06696	TXNDC15 Protein, Human, Recombinant (His) UNQ335,thioredoxin domain containing 15,C5orf14,UNQ...	Human	HEK293 Cells
	TXNDC15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.96 kDa and the accession number is NP_078991.3.
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
TMPH-00739	Thioredoxin-1 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin-1 Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.7 kDa and the accession number is P0AA25.
TMPJ-00826	TXN Protein, Human, Recombinant (His) ADF,TXN,TRX1,Thioredoxin,TRX,ATL-Derived Factor,TRD...	Human	E. coli
	Thioredoxin (TXN) is a member of the Thioredoxin family. Thioredoxin exists as a disulfide-linked homodimer and contains one Thioredoxin domain. Thioredoxin is up-regulated by ionizing radiation. Thioredoxin participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin also plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contri...
TMPY-02797	TXNL4A Protein, Human, Recombinant (His) U5-15kD,thioredoxin-like 4A,DIB1,SNRNP15,TXNL4,BMKS...	Human	E. coli
	DIM1, also known as TXNL4A, is a member of the Dim protein family. The Dim protein family is composed of two classes, DIM1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. Despite their biological and structural similarities, DIM1 and Dim2 proteins differ in many aspects. DIM1 bears distinc...
TMPJ-00720	TXNDC12 Protein, Human, Recombinant (His) TLP19,ERp19,Thioredoxin Domain-Containing Protein 1...	Human	HEK293 Cells
	Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain.
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His) Antioxidant enzyme B166,Alu corepressor 1,Peroxiredoxin-5,PL...	Human	HEK293 Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/a...
TMPH-00072	2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) Thioredoxin-dependent peroxiredoxin BAS1,2-Cys pero...	Arabidopsis thaliana	P. pastoris (Yeast)
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf. 2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96291.
TMPH-00078	Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) 1,4-alpha-D-glucan maltohydrolase,TRBAMY,TR-BAMY,BMY7,Th...	Arabidopsis thaliana	E. coli
	Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active on phosphorylated glucan. Interacts directly with starch or other alpha-1,4-glucan. Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.7 ...
TMPJ-01124	PDIA6 Protein, Human, Recombinant (His) Thioredoxin Domain-Containing Protein 7,P5,ERP5,TXN...	Human	HEK293 Cells
	Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA...
TMPJ-00934	PRDX3 Protein, Human, Recombinant Protein MER5 homolog,Thioredoxin-Dependent Peroxide...	Human	E. coli
	Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with M...
TMPH-03443	GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the presence of Ca(2+). Has peroxidase activity using preferentially thioredoxin as a reducing power. The redox state of the mitochondrial GPX2 is regulated by TRX1 and TRX2 (cytoplasmic thioredoxin), and by TRX3 (mitochondrial matrix thioredoxin). Involved in sporulation. GPX2 Protein, ...
TMPH-02198	TXNRD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
TMPJ-00461	PDIA5 Protein, Human, Recombinant (His) Protein disulfide isomerase-related protein,PDIR,PDIA5,Prote...	Human	HEK293 Cells
	Protein disulfide-isomerase A5 is a 519 amino acids protein that belongs to the protein disulfide isomerase family.It contains 3 thioredoxin domains.It can catalyze the rearrangement of -S-S- bonds in proteins.
TMPH-02196	TXNDC5 Protein, Human, Recombinant (GST)	Human	E. coli
	Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 63.2 kDa and the accession number is Q8NBS9.
TMPJ-01225	PDILT Protein, Human, Recombinant (His) PDILT,Protein Disulfide-Isomerase-Like Protein of the Testis	Human	HEK293 Cells
	Protein Disulfide-Isomerase-Like Protein of the Testis (PDILT) is a protein that belongs to the protein disulfide isomerase family. Human PDILT is synthesized as a 584 amino acid precursor that contains an 20 amino acid signal sequence and a 564 amino acid mature chain. PDILT contains 1 thioredoxin domain lacks the conserved redox-active Cys at position 417 which is replaced by a Ser residue, suggesting that it lacks thioredoxin activity. PDILT is an enzyme in the endoplasmic reticulum in eukary...
TMPH-02197	TXNDC5 Protein, Human, Recombinant	Human	E. coli
	Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 36.2 kDa and the accession number is Q8NBS9.
TMPJ-01268	ERP27 Protein, Human, Recombinant (His) C12orf46,ER Protein 27,Endoplasmic Reticulum Resident Protei...	Human	HEK293 Cells
	Endoplasmic reticulum resident protein 27, also known as ER protein 27, C12orf46 and ERP27, is an endoplasmic reticulum luminal protein which is a member of the protein disulfide isomerase family. ERP27 contains one thioredoxin domain and does not contain a CXXC active site motif. ERP27 is widely expressed in many tissues; it has highest expression in pancreas, with lower levels in spleen, lung, kidney, thymus, and bone marrow. ERP27 interacts with PDIA3 and binds somatostatin-14 via hydrophobic...
TMPY-02890	ERP27 Protein, Human, Recombinant (mFc) endoplasmic reticulum protein 27,C12orf46,PDIA8	Human	HEK293 Cells
	ERP27 contains 1 thioredoxin domain and is a noncatalytic member of the protein disulfide isomerase family. Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide bonds formation, reduction, or isomerization of newly synthesized proteins in the lumen of the endoplasmic reticulum (ER). They act also as chaperones, and are, therefore, part of a quality-control system for the correct folding of the proteins in the same subcellular compartmen...

重组蛋白

Thioredoxin/TRX Protein, Mouse, Recombinant

Cat.No: TMPY-00382

Species: Mouse

Expression System: E. coli

Thioredoxin/TRX Protein, Human, Recombinant

Cat.No: TMPY-02250

Species: Human

Expression System: E. coli

Thioredoxin 2/TRX2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02084

Species: Human

Expression System: E. coli

TXNL4B Protein, Human, Recombinant (His)

Cat.No: TMPY-02723

Species: Human

Expression System: E. coli

PRDX4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01098

Species: Human

Expression System: E. coli

TXNDC17 Protein, Human, Recombinant

Cat.No: TMPY-02572

Species: Human

Expression System: E. coli

TMX2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01404

Species: Human

Expression System: E. coli

TMX1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-05058

Species: Human

Expression System: HEK293 Cells

TXNDC15 Protein, Human, Recombinant (His)

Cat.No: TMPY-06696

Species: Human

Expression System: HEK293 Cells

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Cat.No: TMPY-02271

Species: Human

Expression System: E. coli

Thioredoxin-1 Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00739

Species: E. coli

Expression System: E. coli

TXN Protein, Human, Recombinant (His)

Cat.No: TMPJ-00826

Species: Human

Expression System: E. coli

TXNL4A Protein, Human, Recombinant (His)

Cat.No: TMPY-02797

Species: Human

Expression System: E. coli

TXNDC12 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00720

Species: Human

Expression System: HEK293 Cells

PRDX5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00933

Species: Human

Expression System: HEK293 Cells

2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)

Cat.No: TMPH-00072

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Cat.No: TMPH-00078

Species: Arabidopsis thaliana

Expression System: E. coli

PDIA6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01124

Species: Human

Expression System: HEK293 Cells

PRDX3 Protein, Human, Recombinant

Cat.No: TMPJ-00934

Species: Human

Expression System: E. coli

GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03443

Species: Saccharomyces cerevisiae

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02198

Species: Human

Expression System: E. coli

PDIA5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00461

Species: Human

Expression System: HEK293 Cells

TXNDC5 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02196

Species: Human

Expression System: E. coli

PDILT Protein, Human, Recombinant (His)

Cat.No: TMPJ-01225

Species: Human

Expression System: HEK293 Cells

TXNDC5 Protein, Human, Recombinant

Cat.No: TMPH-02197

Species: Human

Expression System: E. coli

ERP27 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01268

Species: Human

Expression System: HEK293 Cells

ERP27 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-02890

Species: Human

Expression System: HEK293 Cells

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