PAO-Nap

Name: PAO-Nap
Brand: TargetMol
SKU: T36399
Rating: 4.5 (1 reviews)

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产品编号 T36399Cas号 1613402-20-2

PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1].

PAO-Nap

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产品编号 T36399Cas号 1613402-20-2

规格	价格	库存	数量
5 mg	¥ 2,397	待询
10 mg	¥ 3,855	待询

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PAO-Nap 相关产品

产品介绍

生物活性

产品描述	PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1].
体外活性	PAO exhibits IC50 values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1].

化学信息

分子量	509.394
分子式	C₂₄H₂₄AsN₃O₅
CAS No.	1613402-20-2
密度	no data available

储存&溶解度

存储	keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.