bop

BOP is anantagonist of alpha4beta1/alpha9beta1 integrins. BOP rapidly mobilizes long-term multi-lineage reconstituting hematopoietic stem cells (HSC).

BOP-JF549 is a fluorescent dual α9β1 α4β1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor® 549. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 549 nm; emission maximum = 571 nm.

BOP-JF646 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor®646. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 655 nm; emission maximum = 672 nm.

BOP (hexafluorophosphate) 是一种高纯度生化试剂，适合作为生物材料或有机合成中间体，广泛应用于生命科学领域的研究与实验。

BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.

I-BOP 是血栓素 A2 受体 (TP) 的激动剂（KD=0.61 nM）。I-BOP 可通过激活血管平滑肌中的 PI3K 通路促进细胞增殖。

Totrombopag (SB559448) 是对RSV 聚合酶有作用的候选化合物。

Carboplatin (JM-8) 是一种顺铂衍生物，一种 DNA 合成抑制剂。Carboplatin 能够与 DNA 结合，抑制复制和转录并诱导细胞死亡。Carboplatin 具有抗肿瘤活性。

Eltrombopag (SB-497115-GR) 是一种具有巨核细胞生成刺激活性的口服活性血小板生成素受体激动剂，可结合并刺激血小板血小板生成素受体，用于血小板减少的某些病症研究。

Eltrombopag Olamine (Eltrombopag diethanolamine salt) 是 Eltrombopag 的口服活性乙醇胺盐，是一种血小板生成素(TPO)受体激动剂，用于血小板减少的某些病症研究。

Avatrombopag (YM477) 是一种新型口服血小板生成素 (TPO) 受体激动剂，可激活 TPO 受体并增加巨核细胞增殖 分化和血小板生成。

Clebopride malate 是多巴胺拮抗剂，可用于功能性胃肠功能紊乱的研究。

Ebopiprant (OBE022) 是一个可口服且具有选择性和高效性的前列腺素 F2α (PGF2α) 受体拮抗剂，干扰 PGF0126α 与 FPR 的结合，可用于研究肥胖。

TBOPP 是DOCK1的选择性抑制剂(IC50:8.4 μM)。它以高亲和力与DOCK1DHR-2 结构域结合 (Kd 为 7.1 μM) ，对多种肿瘤均具有抗肿瘤活性。

Carboprost tromethamine 是合成的前列腺素 F2α的15-甲基类似物，能有效促进子宫的规律收缩，显着减少产中及产后出血量。

TCPOBOP 是一种组成型雄烷受体激动剂，可诱导强大的肝细胞增殖和肝肿大。它通过改变 Bcl-2 蛋白来减少 Fas 诱导的小鼠肝损伤。

Carboprost (15(S)-15-Methyl Prostaglandin F2α) 是一种前列腺素 F2α 的代谢稳定的合成类似物。它能够刺激子宫收缩并引起流产，可用于子宫收缩乏力引起的产后出血，以及在妊娠中期终止妊娠。

Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity.

Fluoroclebopride 能够与多巴胺受体可逆结合，用18F 标记后可用作 PET 探针，能够标记多种猴子模型中的 D2 D3 多巴胺受体。

Sibopirdine is a new type of cognitive enhancer and intelligence booster that has been studied as a cognitive enhancer for the treatment of Alzheimer's disease.

Bopindolol is a non-selective β-adrenergic receptor antagonist. In vivo, bopindolol decreases heart rate and blood pressure and attenuates ischemia-induced myocardial acidosis in dogs. Formulations containing bopindolol have been used to treat essential and renovascular hypertension.

(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia.

Avatrombopag hydrochloride (AKR-501) is an orally active, nonpeptide agonist of the thrombopoietin (TPO) receptor with an EC 50 of 3.3 nM. It effectively mimics the biological activities of TPO, stimulating platelet production by activating the intracellular signaling system and facilitating the generation of platelets and megakaryocytes from hemopoietic precursor cells. Additionally, Avatrombopag hydrochloride serves as a substrate for cytochrome P450 (CYP) 2C9 and CYP3A.

Hetrombopag 是一种 thrombopoietin receptor 的有效激动剂。Hetrombopag 具有良好的耐受性且安全性可控。Hetrombopag 具有潜力进行免疫性血小板减少症的研究。