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TargetMol产品目录中 "

sf 11

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  • 抑制剂&激动剂
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    TargetMol | Inhibitors_Agonists
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    48
    TargetMol | Recombinant_Protein
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    TargetMol | Antibody_Products
  • SF 11
    T23349443292-81-7
    SF 11是一种有效的脑渗透神经肽 Y Y2 受体拮抗剂 (IC50=199 nM)。具有抗抑郁药样活性。
    • ¥ 298
    In stock
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    TargetMol | Inhibitor Sale
  • LY294002
    SF 1101, NSC 697286, LY 294002
    T2008154447-36-6
    LY294002 (SF 1101) 是一种 PI3K 的广谱抑制剂,抑制 PI3Kα、PI3Kδ 和 PI3Kβ (IC50=0.5 0.57 0.97 μM)。LY294002 也是 DNA-PK 抑制剂 (IC50=1.4 μM) 和 CK2 抑制剂 (IC50=98 nM)。LY294002 可以激活凋亡和自噬。
    • ¥ 531
    In stock
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    TargetMol | Inhibitor Hot
  • SF1126
    T16875936487-67-1
    SF1126 is a relevant pan and dual first-in-class PI3K BRD4 inhibitor. SF1126 is an RGDS-conjugated LY294002 prodrug, which is designed to exhibit increased solubility and bind to specific integrins within the tumor compartment.
    • ¥ 10600
    待询
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    数量
  • LY-294002 hydrochloride
    LY294002 hydrochloride, LY 294002 hydrochloride
    T4079934389-88-5
    LY-294002 hydrochloride (NSC 697286) 是一种合成的 PI3Kα δ β 分子抑制剂(IC50:0.5 0.57 0.97 μM,在无细胞试验中);在溶液中比 Wortmannin 更稳定,也是自噬体形成的阻断剂。
    • ¥ 233
    In stock
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  • CGP 71683 (free base)
    T70061192321-23-6
    CGP 71683 (free base) is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.
    • ¥ 10600
    1-2周
    规格
    数量
  • Aquastatin A
    T38069153821-50-2
    Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K., et al.Aquastatin A, an inhibitor of mammalian adenosine triphosphatases from Fusarium aquaeductuum. Taxonomy, fermentation, isolation, structure determination and biological propertiesJ. Antibiot. (Tokyo)46(11)1648-1657(1993) 2.Kwon, Y.-J., Fang, Y., Xu, G.-H., et al.Aquastatin A, a new inhibitor of enoyl-acyl carrier protein reductase from Sporothrix sp. FN611Biol. Pharm. Bull.32(12)2061-2064(2009) 3.Seo, C., Soh, J.H., Oh, H., et al.Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp. SF-5060Bioorg. Med. Chem. Lett.19(21)6095-6097(2009)
    • ¥ 12600
    35日内发货
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