Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T67874 | PFKFB3-IN-2
化合物PFKFB3-IN-2
|
794552-84-4 | 98% |
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PFKFB3-IN-2是一种6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶3 (PFKFB3)抑制剂。在体内,对PFKFB3进行反义治疗可降低肿瘤生长速度。 | ||||
T60048 | WAY-640509
化合物WAY-640509
|
851185-20-1 | 98% |
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WAY-640509是一种葡糖脑苷酶抑制剂。 | ||||
T8990 | ML266
化合物ML266
|
1462267-08-8 | 98% |
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ML266 是葡萄糖脑苷脂酶 (GCase) 分子伴侣, IC50值为 2.5 µM。ML266与 GCase 结合并将其转运至溶酶体,恢复 GCase 酶的活性。ML266 不会抑制 GCase 的活性。ML266 具有研究戈谢病的潜力。 | ||||
T14212 | AMG-1694
化合物AMG-1694
|
1361217-07-3 | 98% |
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AMG-1694 是一种强效的葡萄糖激酶-葡萄糖激酶调节蛋白(GK-GKRP)干扰物,能促进 GK-GKRP 复合物的解离,其 IC50 值为 7 nM,从而间接提高 GK 酶的活性。AMG-1694 可使几种啮齿动物糖尿病模型的血糖水平恢复正常,并降低糖尿病动物而非正常血糖动物的血糖。AMG-1694 能有效逆转 GK... | ||||
T3386 | Kaempferitrin
山奈苷
|
482-38-2 | 98% |
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Kaempferitrin 是天然黄酮苷类化合物,具有缓解疼痛、抗糖尿病、消炎、抗肿瘤和化疗作用,可激活胰岛素信号传导。 | ||||
TN5192 | Tuberosin
化合物 TN5192
|
41347-45-9 | 98% |
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Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in a dose dependent manner.... | ||||
TN5090 | Tachioside
化合物 TN5090
|
109194-60-7 | 98% |
|
Tachioside has antiobesity, antioxidant and α-glucosidase inhibitory activities, it decreases lipid content in 3T3-L1 adipocytes by inhibiting lipogenesis, shows... | ||||
TN4793 | Pinoresinol diacetate
化合物 TN4793
|
32971-25-8 | 98% |
|
Pinoresinol diacetate inhibits the enzyme α-glucosidase in vitro and may therefore act as a hypoglycemic agent. | ||||
T10751 | Cefetrizole
头孢三唑
|
65307-12-2 | 98% |
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Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM). | ||||
TN5094 | Tangshenoside I
党参苷 I
|
117278-74-7 | 98% |
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Tangshenoside I might be a potential bioactive marker related to the hematopoietic and immunologic functions of Codonopsis Radix, which could be recommended as t... | ||||
TN3745 | Cyclomusalenone
化合物 TN3745
|
30452-60-9 | 98% |
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Cyclomusalenone is a potent α-glucosidase inhibitor. | ||||
T11749 | KDM4-IN-2
化合物 T11749
|
2369607-62-3 | 98% |
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KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively. | ||||
TN4174 | Guajadial
化合物 TN4174
|
959860-49-2 | 98% |
|
Guajadial shows α-glucosidase inhibitory activities significantly and its activity was better than that of Acarbose.Guajadial may act as Selective Estrogen Recep... | ||||
T16480 | PF-04991532
化合物 T16480
|
1215197-37-7 | 98% |
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PF-04991532 is an effective, hepatoselective glucokinase activator. It has EC50s of 80 and 100 nM in human and rat, respectively. | ||||
T6759 | AP-III-a4
化合物AP-III-a4
|
1177827-73-4 | 98% |
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AP-III-a4 是第一个非底物类似物,可直接与烯醇酶结合,IC50=0.576 uM,可阻碍体内癌细胞转移。 | ||||
T64320 | ML251
化合物ML251
|
1486482-16-9 | 98% |
|
ML251 是一种有效的新型纳摩尔 T. brucei 和 T. cruzi 磷酸果糖激酶抑制剂,对 T. brucei PFK 和 T. cruzi PFK 的 IC50值为 0.37和 0.13 μM,可研究寄生虫。 | ||||
T2455 | PFK-015
化合物PFK-015
|
4382-63-2 | 98% |
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PFK015是一种有效的 PFKFB3 抑制剂,对重组PFKFB3的IC50为110 nM。它能抑制 Y 细胞中的 PFKFB3 活性,IC50为20 nM。 | ||||
T22223 | 3PO
化合物3PO
|
18550-98-6 | 98% |
|
3PO 是一种 PFKFB3 的小分子抑制剂,IC50值为22.9 μM。它抑制几种人类恶性造血和腺癌细胞系的增殖,IC50在1.4到24 μM 之间。它抑制葡萄糖摄取,并降低 Fru-2,6-BP、乳酸、ATP、NAD+ 和 NADH 的细胞内浓度。 | ||||
T3312 | AM-2394
化合物AM2394
|
1442684-77-6 | 98% |
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AM2394 是新型的 glucokinase 激活剂 (GKA)。它能够激活葡萄糖激酶 (GK),EC50=60 nM。 | ||||
T26712 | AZD-1656
化合物AZD-1656
|
919783-22-5 | 98% |
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AZD1656 是口服有效的葡萄糖激酶选择性激活剂,EC50为 60 nM。AZD1656在2 型糖尿病中有研究的价值。 |