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49

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8610	sun 呋喃并吡咯甲酸,4H-Furo[3,2-b]pyrrole-5-carboxylic acid	Others	Others
	Sun(4H-Furo[3,2-b]pyrrole-5-carboxylic acid) 是一种口服有效的 DAAO(DAO) 抑制剂。
T3714	SUN11602 SUN 11602	ERK; FGFR	Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
	SUN11602 是新型的碱性苯胺化合物，具有成纤维细胞生长因子特性。
T23406	SUN B8155 SUN-B 8155	Others	Others
	calcitonin (CT) receptor agonist
T12596	(4E)-SUN9221	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	(4E)-SUN9221 是一种有效的 α1-adrenergic 受体和 5-HT2 受体双重拮抗剂，在高血压大鼠中显示出抗高血压和抗血小板聚集活性。
T7811	Pilsicainide HCl SUN 1165,盐酸吡西卡呢	Sodium Channel	Membrane transporter/Ion channel
	Pilsicainide HCl (SUN 1165) 是一种纯钠通道阻滞剂。
T28884	SUN-C5174 SUNC-5174
	SUN-C5174 is a sleective 5-HT2 antagonist (pA2=8.98+/-0.06). SUN C5174 showed a marked inhibitory effect on the platelet aggregation induced by serotonin in combination with collagen and adenosine diphosphate (ADP) in canine or human platelet-rich plasma
T13040	SUN 1334H	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	SUN 1334H is a potent, orally active, highly selective antagonist of H1 receptor(Ki of 9.7 nM).
T28414	Piclozotan SUN-N-4057,SUN4057,SUNN-4057,SUN-4057,SUNN4057	5-HT Receptor	GPCR/G Protein; Neuroscience
	Piclozotan (anhydrous) 是一种 5-HT1A 受体激动剂，在短暂的大脑中动脉闭塞（t-MCAO）模型中表现出显着的神经保护活性,可以改善晚期帕金森病患者的运动并发症。
T69727	ADA-07
	ADA-07 is a TOPK inhibitor which interacts with TOPK at the ATP-binding pocket and inhibits its kinase activity, thereby suppressing SUV-induced phosphorylation of ERK1/2, p38, and JNKs, and subsequently inhibiting AP-1 activity.
T61666	SUN13837
	SUN13837 is an orally active, potent modulator of the fibroblast growth factor receptor (FGFR) with the ability to penetrate the blood-brain barrier (BBB). It exhibits neuroprotective activity and holds promise for furthering research on neurodegenerative diseases [1].
T69728	SUN49199
	SUN49199, also known as NaV1.7 Blocker-13, is a novel selective blocker of NaV1.7 with little affinity for NaV 1.2, 1.3, or 1.6, being more potent at human vs guinea pig NaV1.7. SUN49199 was reported in Journal of Pharmacology and Experimental Therapeutics (2017), 361(1), 172-180. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/na...
T0499	Oxybenzone 二苯酮-3,KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,紫外线吸收剂UV-9,Escalol 567	Apoptosis; Retinoid Receptor; Autophagy	Apoptosis; Autophagy; Metabolism
	Oxybenzone (Eusolex 4360) 是晒黑和皮肤保护剂中常用的紫外线过滤剂。它是二苯甲酮的衍生物，用作破坏内分泌的化学物质，可穿透胎盘和血脑屏障。它损害自噬，改变表观遗传状态并破坏凋亡神经元细胞中的类维生素 X 受体信号传导。
T76692	Mosunetuzumab BTCT-4465A	Others	Others
	Mosunetuzumab (BTCT-4465A) 是一种基于免疫球蛋白 G1 且靶向 CD20 (B 细胞) 和 CD3 (T 细胞) 的人源化抗体。Mosunetuzumab 重定向 T 细胞以接合和消除恶性 B 细胞，可用于研究复发或难治性 (R/R) B 细胞非霍奇金淋巴瘤 (B-NHL)和难治性滤泡性淋巴瘤。
T0374	Sunitinib Malate 苏尼替尼苹果酸盐,Sutent,SU 11248 (Malate),SU 11248,Sunitinib	Apoptosis; Mitophagy; VEGFR; FLT; IRE1; PDGFR; c-Kit; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
	Sunitinib Malate (Sunitinib) 是一种基于吲哚酮的酪氨酸激酶抑制剂，抑制 VEGFR2和 PDGFRβ的 IC50分别为80 nM 和 2 nM。它是 ATP 竞争性抑制剂，可通过抑制自身磷酸化和随后的 RNase 激活来有效抑制 Ire1α的磷酸化。
T60128	N,N-Didesethyl Sunitinib Hydrochloride	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	N,N-Didesethyl Sunitinib Hydrochloride 是一种有效的AMPK 抑制剂，对AMPKα1和AMPK2的IC50分别为393nM 和141nM。
T61699	Osunprotafib AC 484,Osunprotafib,AC484,ABBV-CLS-484	Phosphatase	Metabolism
	ABBV-CLS-484 (Osunprotafib) 是一种具有亚纳摩尔活性的有效的PTPN2抑制剂，具有抗肿瘤活性，可增强T细胞抗肿瘤免疫力。ABBV-CLS-484可用于治疗肿瘤、食管癌和消化系统疾病。
T39463	Asundexian BAY 2433334,Asundexian,BAY2433334,BAY-2433334	Factor Xa	Metabolism
	Asundexian (BAY-2433334) 是一种高效且具有口服活性凝血因子 FXIa 抑制剂，可直接且可逆地与FXIa 的活性位点结合，从而抑制其活性。Asundexian 对缓冲液中的人 FXIa 的 IC50 为 1 nM。Asundexian 具有抗肿瘤活性，可用于研究急性缺血性卒中、短暂性脑缺血发作和缺血性卒中。
T9304	(S)-Sunvozertinib N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide,DZD9008	EGFR; HER	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	(S)-Sunvozertinib (DZD9008) 是 Sunvozertinib 的 S-对映体，能够抑制EGFR 外显子 20 NPH 和 ASV 插入、EGFR L858R/T790M 突变及 Her2 外显子 20 YVMA 插入，也能够抑制BTK。
T12145L	N-Desethylsunitinib hydrochloride	VEGFR; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	N-Desethylsunitinib hydrochloride 是舒尼替尼的主要且具有药理活性的代谢物，是有效的 ATP 竞争性 VEGFR、PDGFRβ 和 KIT 抑制剂。
T9197	Sisunatovir hydrochloride RV521 HCl,Sisunatovir HCl	RSV	Microbiology/Virology
	Sisunatovir hydrochloride (RV521 HCl) 是一种可口服的 RSV-F 蛋白抑制剂，在体外对一组 RSV-A 和 RSV-B 病毒的临床分离株表现出有效的疗效，对 RSV-A 和 RSV-B 分离株的IC50分别为 1.4 nM 和 1.0 nM。
T4474	Asunaprevir BMS-650032,阿那匹韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Asunaprevir (BMS-650032) 是一种有口服活性的 HCV NS3 蛋白酶抑制剂，IC50值为 0.2 nM-3.5 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T64124	Sunvozertinib DZD9008,DZD 9008,DZD-9008	EGFR; BTK	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Sunvozertinib (DZD9008) 是一种有效的 ErbBs 和 BTK 抑制剂，对EGFR、Her2和突变型表皮生长因子有抑制作用。 Sunvozertinib 显示 EGFR 外显子 20 NPH 插入、EGFR 外显子 20 ASV 插入、EGFR L858R 和 T790M 突变以及 Her2 外显子 20 YVMA 和 EGFR WT A431 有抑制作用， IC50 分别为 20.4、20.4、1.1、7.5 和 80.4 nM 。
T0374L	Sunitinib 苏尼替尼,舒尼替尼,SU 11248	Apoptosis; Mitophagy; VEGFR; FLT; IRE1; PDGFR; c-Kit; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
	Sunitinib (SU 11248) 是一种多靶点受体酪氨酸激酶 (RTK) 抑制剂，可以抑制 VEGFR2 和 PDGFRβ (IC50=80/2 nM)。Sunitinib 具有抗肿瘤活性，可以用于治疗肾癌和胃肠道肿瘤。
T7599	Sunifiram 桑尼菲拉姆,DM-235,桑尼非拉姆	iGluR	Membrane transporter/Ion channel; Neuroscience
	Sunifiram (DM-235) 是一种 ampakine 样促智剂。
T76897	Acasunlimab
	Acasunlimab (GEN1046) 是一种双特异性抗体 (bsAb)，靶向PD-L1和4-1BB。Acasunlimab 通过有条件的4-1BB 刺激增强 T 细胞和 NK 细胞功能，同时构成性地阻断PD-1/PD-L1抑制轴。Acasunlimab 可用于癌症的研究。
T28885	Sunepitron HCl CP 93,393,CP93,393,CP-93393,CP93393,CP 93393,CP-93,393
	Sunepitron is a combined α2-adrenergic receptor antagonist and 5-HT1A receptor agonist.
T24747	Sisunatovir RV-521,RV521,RV 521,RV521 free base
	RV521 is a highly effective fusion inhibitor. It designed to treat RSV disease by the target of a surface protein that mediates RSV binding to cellular receptors.
T74127	N-Desethyl Sunitinib hydrochloride
	N-Desethyl Sunitinib (SU-12662) (hydrochloride) 是 Sunitinib 的代谢物。Sunitinib 是有效的，ATP 竞争的VEGFR，PDGFRβ和KIT 抑制剂，能够抑制VEGFR-1，VEGFR-2，VEGFR-3，PDGFRβ和 KIT 的活性，Ki 值分别为 2，9，17，8 和 4 nM。
T62482	Sunobinop
	Sunobinop (S 117957) 是一种阿片受体样孤儿受体 (ORL1) 调节剂。
T125327	Citrusunshitin A
	Citrusunshitin A 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125327，CAS号为 2192316-07-5。
T39807	Suntinorexton
	Suntinorexton, a heterocyclic compound, is a selective agonist of orexin type 2 receptors.
T124612	Kusunokinin
	Kusunokinin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124612。
T13039	Sunitinib-d10 Sunitinib D10,SU 11248 D10	VEGFR; PDGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Sunitinib D10 is a deuterium labeled Sunitinib. Sunitinib is a inhibitor of multi-targeted receptor tyrosine kinase(IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively).
T70979	Sunepitron Free Base
	Sunepitron Free Base is a combined 5-HT1A receptor agonist and α₂-adrenergic receptor antagonist. It was previously under development by Pfizer for the treatment of depression and anxiety. It made it to phase III clinical trials before being discontinued.
T76911	Asunercept
	Asunercept (APG101; CAN008) 是一种靶向CD95L 的可溶性CD95-Fc 融合蛋白。Asunercept 通过选择性地与CD95L 结合，来破坏CD95/CD95L 的信号传导。Asunercept 可用于多形性胶质母细胞瘤 (GBM)、骨髓增生异常综合征 (MDS) 以及移植物抗宿主病 (GvHD) 的研究。
T80601	Pegsunercept PEG sTNF-RI
	Pegsunercept (PEG sTNF-RI)，一种偶联有pegol结构的特异性靶向TNFA单克隆抗体。
T12145	N-Desethyl Sunitinib N-去乙基-舒尼替尼,SU-11662	VEGFR; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	N-Desethyl Sunitinib (SU-11662) 是 Sunitinib 的代谢物。其中 Sunitinib 是有效的以及ATP 竞争的VEGFR、PDGFRβ和KIT 抑制剂，能够抑制 VEGFR -1 (Ki:2 nM) 、VEGFR-2 (Ki:9 nM) 、VEGFR-3 (Ki:17 nM) 、PDGFRβ (Ki:8 nM) 、KIT (Ki:4 nM) 的活性。
T0016	Mexenone Mesenone,Uvistat,Benzophenone-10,美克西酮	Others	Others
	Mexenone (Uvistat) 是二苯甲酮型紫外线过滤剂，具有防晒作用。
TP1097	Melanotan I 美拉诺坦,美拉诺坦 I,[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I	Others	Others
	Melanotan I 是一种非特异性黑素皮质激素受体 (MCR) 激动剂，是一种 α- 黑素细胞刺激激素 (α-MSH) 类似物，皮下注射可增加黑色素在皮肤中的含量。Melanotan I 可用于辅助美黑。Melanotan I 可用于预防阳光诱发皮肤癌，可用于研究黑色素瘤和男性勃起功能障碍。
T69607	Dersimelagon phosphate
	Dersimelagon phosphate is a selective melanocortin-1 receptor (MC1R) agonist that increases skin melanin without sun exposure and is being developed to increase light tolerance in EPP/XLP patients.
T60482	Pilsicainide
	Pilsicainide (SUN 1165 free acid)是一种有效的 Ic 类抗心律失常药。Pilsicainide 是一种有效的钠通道阻滞剂。
T36723	Desmethyl Ranolazine
	Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine .1It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. 1.Wang, Y., Chen, X., Sun, Z., et al.Development and validation of a sensitive LC-MS/MS assay for simultaneous quantitation of ranolazine and its three metabolites in human plasmaJ. Chromatogr. B889-89010-16(2012)
T37335	N-3-hydroxybutyryl-L-Homoserine lactone
	N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.1,2 It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.3 \|1. Purohit, A.A., Johansen, J.A., Hansen, H., et al. Presence of acyl-homoserine lactones in 57 members of the Vibrionaceae family. J. Appl. Microbiol. 115(3), 835-847 (2013).\|2. Feng, Z., Sun,...
T38329	CU-76
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas, R., Sun, L., Anderson, R., et al.Discovery of small-molecule cyclic GMP-AMP sy...
T37889	BHBM
	BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1 In vivo, BHBM (1.2 mg/kg per day) increases survival in a mouse model of C. neoformans infection. \|1. Haranahalli, K., Lazzarini, C., Sun, Y., et al. SAR studies on aromatic acylhydrazone-based inhibitors of fungal...
T38328	CU-32
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective for cGAS over toll-like receptors (TLRs) at 50 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas...
T36737	3-hydroxy Myristic Acid methyl ester
	3-hydroxy Myristic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in E. camaldulensis and E. torelliana extracts. [1] It is active against M. tuberculosis (MIC = 49.5 μg/ml) and is non-cytotoxic to Vero cells (IC50 = >100 μM). 3-hydroxy Myristic acid methyl ester is also a volatile compound that contributes to the aroma of red wild strawberries (F. pentaphylla) but is not present in cultivated strawberries (Fragaria x ananassa).[2] Reference：[1]. Lawal, T.O., Ade...
T36486	Benpyrine
	Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research[1]. Benpyrine (5-20 μM; 14 hours; RAW264.7 cells) pretreatment results in a dose-dependent decrease in the phosphorylation of IκBα in RAW264.7 cells (stimulated with 10 ng/mL TNF-α or 1 μg/mL LPS). Benpyrine abo...
T35426	β-Defensin-1 (human) (trifluoroacetate salt)
	β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus,B. breve,B. vulgatus,L. fermentum,B. longum, andS. thermophilusin an antimicrobial radial diffusion assay.2β-Defensin-1 also inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius, and of susceptibleM. tuberculosisH37Rv but no...

化合物

Cat.No: T8610

Synonym: 呋喃并吡咯甲酸,4H-Furo[3,2-b]pyrrole-5-carboxylic acid

Target: Others

Cat.No: T3714

Synonym: SUN 11602

Target: ERK, FGFR

Cat.No: T23406

Synonym: SUN-B 8155

Target: Others

Cat.No: T12596

Target: 5-HT Receptor, Adrenergic Receptor

Pilsicainide HCl

Cat.No: T7811

Synonym: SUN 1165,盐酸吡西卡呢

Target: Sodium Channel

Cat.No: T28884

Synonym: SUNC-5174

Cat.No: T13040

Target: Histamine Receptor

Cat.No: T28414

Synonym: SUN-N-4057,SUN4057,SUNN-4057,SUN-4057,SUNN4057

Target: 5-HT Receptor

Cat.No: T69727

Cat.No: T61666

Cat.No: T69728

Cat.No: T0499

Synonym: 二苯酮-3,KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,紫外线吸收剂UV-9,Escalol 567

Target: Apoptosis, Retinoid Receptor, Autophagy

Cat.No: T76692

Synonym: BTCT-4465A

Target: Others

Sunitinib Malate

Cat.No: T0374

Synonym: 苏尼替尼苹果酸盐,Sutent,SU 11248 (Malate),SU 11248,Sunitinib

Target: Apoptosis, Mitophagy, VEGFR, FLT, IRE1, PDGFR, c-Kit, Autophagy

N,N-Didesethyl Sunitinib Hydrochloride

Cat.No: T60128

Target: AMPK

Cat.No: T61699

Synonym: AC 484,Osunprotafib,AC484,ABBV-CLS-484

Target: Phosphatase

Cat.No: T39463

Synonym: BAY 2433334,Asundexian,BAY2433334,BAY-2433334

Target: Factor Xa

(S)-Sunvozertinib

Cat.No: T9304

Synonym: N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide,DZD9008

Target: EGFR, HER

N-Desethylsunitinib hydrochloride

Cat.No: T12145L

Target: VEGFR, PDGFR, c-Kit

Sisunatovir hydrochloride

Cat.No: T9197

Synonym: RV521 HCl,Sisunatovir HCl

Target: RSV

Cat.No: T4474

Synonym: BMS-650032,阿那匹韦

Target: HCV Protease, SARS-CoV

Sunvozertinib

Cat.No: T64124

Synonym: DZD9008,DZD 9008,DZD-9008

Target: EGFR, BTK

Cat.No: T0374L

Synonym: 苏尼替尼,舒尼替尼,SU 11248

Target: Apoptosis, Mitophagy, VEGFR, FLT, IRE1, PDGFR, c-Kit, Autophagy

Cat.No: T7599

Synonym: 桑尼菲拉姆,DM-235,桑尼非拉姆

Target: iGluR

Cat.No: T76897

Sunepitron HCl

Cat.No: T28885

Synonym: CP 93,393,CP93,393,CP-93393,CP93393,CP 93393,CP-93,393

Cat.No: T24747

Synonym: RV-521,RV521,RV 521,RV521 free base

N-Desethyl Sunitinib hydrochloride

Cat.No: T74127

Cat.No: T62482

Citrusunshitin A

Cat.No: T125327

Suntinorexton

Cat.No: T39807

Cat.No: T124612

Sunitinib-d10

Cat.No: T13039

Synonym: Sunitinib D10,SU 11248 D10

Target: VEGFR, PDGFR

Sunepitron Free Base

Cat.No: T70979

Cat.No: T76911

Cat.No: T80601

Synonym: PEG sTNF-RI

N-Desethyl Sunitinib

Cat.No: T12145

Synonym: N-去乙基-舒尼替尼,SU-11662

Target: VEGFR, PDGFR, c-Kit

Cat.No: T0016

Synonym: Mesenone,Uvistat,Benzophenone-10,美克西酮

Target: Others

Cat.No: TP1097

Synonym: 美拉诺坦,美拉诺坦 I,[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I

Target: Others

Dersimelagon phosphate

Cat.No: T69607

Cat.No: T60482

Desmethyl Ranolazine

Cat.No: T36723

N-3-hydroxybutyryl-L-Homoserine lactone

Cat.No: T37335

Cat.No: T38329

Cat.No: T37889

Cat.No: T38328

3-hydroxy Myristic Acid methyl ester

Cat.No: T36737

Cat.No: T36486

β-Defensin-1 (human) (trifluoroacetate salt)

Cat.No: T35426

Cat. No.	Product Name	Target	Signaling Pathways
T19278	Dicaprylyl carbonate 碳酸二辛酯,Dimethyl carbonate	Others	Others
	Dicaprylyl carbonate (Dimethyl carbonate) 是植物来源的固体脂肪，是干燥润肤剂。它具有强大的皮肤相容性和全面的性能，如防晒滤光片的增溶和分散能力。
TN2245	Sunset Yellow FCF Food Yellow 3,Orange Yellow S,Sunset yellow,CI 15985	Androgen Receptor	Endocrinology/Hormones
	Sunset Yellow FCF (Sunset yellow) 是一种橙色偶氮染料，吸光度具有pH 依赖性。Sunset Yellow FCF 可在食品，化妆品和药品中使用，在许多食品中用作着色剂食品添加剂，它们可能具有细胞毒性和遗传毒性，因此在使用这些材料作为食品添加剂时必须小心。
T0433	Artesunate WR-256283,青蒿琥酯	Virus Protease; Ferroptosis; STAT; Parasite	Apoptosis; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Artesunate (WR-256283) 是治疗疟疾的青蒿素组药物的一部分。它是青蒿素的半合成衍生物，具有水溶性。
TN6278	Norushinsunine Michelalbine,白兰花碱
	Norushinsunine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6278，CAS号为 3175-84-6。
T31371	Nasunin Violanin,Delphanin
	Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.
T0073	Octinoxate 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,甲氧基肉桂酸辛酯,Octyl methoxycinnamate,对甲氧基肉桂酸辛酯	Others	Others
	Octinoxate (Octyl 4-methoxycinnamate) 能够吸收来自太阳的 UV-B 射线，保护皮肤免受损伤，也可用于减少疤痕的外观，常用于是防晒霜和唇膏等化妆品中。
T37451	Stachybotrysin B
	Stachybotrysin B is a fungal metabolite originally isolated from S. chartarum and has antiviral and anticancer activities.1,2 It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM).1 Stachybotrysin B is cytotoxic to K562, HeLa, and HL-60 cells (IC50s = 21.72, 39.63, and 18.5 μM, respectively).2 \|1. Zhao, J., Feng, J., Tan, Z., et al. Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. J. Nat. Prod. 80(6), 1819-1826 (2017).\|2. Ma, X.-h., Zhen...
T36179	Aspulvinone O
	Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulvinone O inhibits aspartate transaminase 1 (GOT1; Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM).2 It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5 mg/kg) redu...

天然产物

Dicaprylyl carbonate

Cat.No: T19278

Synonym: 碳酸二辛酯,Dimethyl carbonate

Target: Others

Sunset Yellow FCF

Cat.No: TN2245

Synonym: Food Yellow 3,Orange Yellow S,Sunset yellow,CI 15985

Target: Androgen Receptor

Cat.No: T0433

Synonym: WR-256283,青蒿琥酯

Target: Virus Protease, Ferroptosis, STAT, Parasite

Cat.No: TN6278

Synonym: Michelalbine,白兰花碱

Cat.No: T31371

Synonym: Violanin,Delphanin

Cat.No: T0073

Synonym: 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,甲氧基肉桂酸辛酯,Octyl methoxycinnamate,对甲氧基肉桂酸辛酯

Target: Others

Stachybotrysin B

Cat.No: T37451

Cat.No: T36179

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