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35
Cat. No. | Product Name | Target | Signaling Pathways |
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TP2503 |
FOR-MET-PHE-OH acetate
FOR-MET-PHE-OH acetate(22008-60-2 Free base) |
Others | Others |
FOR-MET-PHE-OH acetate 在以趋化有效浓度使用时显着增加粒细胞粘附性。 | |||
TP1042 |
Palmitoyl Tetrapeptide-3
Rigin,棕榈酰四肽-7/棕榈酰四肽-3 |
Others | Others |
Palmitoyl Tetrapeptide-3 (Rigin) 是一种具有刺激吞噬活性的合成多肽,对应人免疫球蛋白重链的第 341-344 氨基酸序列。 | |||
T4042 |
Talabostat mesylate
Val-boroPro,PT100 |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Talabostat mesylate (PT100) 是一种具有口服活性和非选择性的二肽基肽酶 IV 抑制剂(IC50< 4 nM;Ki= 0.18 nM)。Talabostat mesylate 是成纤维细胞活化蛋白的第一个临床抑制剂(IC50= 560 nM),抑制 DPP8/9 (IC50= 4/11 nM;Ki= 1.5/0.76 nM),静息细胞脯氨酸二肽酶(IC50= 310 nM)、DPP2 和一些其他 DASH 家族酶。Talabostat mesylate 具有抗肿瘤和造血刺激活性 。 | |||
T34465 |
S 2484
S-2484,S2484,Pyro-glu-pro-val-pna |
||
S 2484 is a chromogranic specific granulocyte elastase substrate. | |||
T27251 |
Elasnin
|
||
Elasnin is a reversible inhibitor of elastase for human granulocyte and pancreatic enzymes with IC50 values of 1.3 and 30 µg/ml, respectively. | |||
T80585 |
Anti-Mouse GM-CSF Antibody (MP1-22E9)
|
c-Fms | Tyrosine Kinase/Adaptors |
Anti-MouseGM-CSFAntibody 为特异性针对小鼠GM-CSF的IgG2a类免疫球蛋白抗体,由大鼠血清中提取。 | |||
TP2340 |
Hemoregulatory peptide 5b
hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide |
||
Hemoregulatory peptide 5b is a synthetic analog of granulocyte chalone which initially identified in extracts of rodent bone marrow and human leukocytes. Monomer inhibits both formations of GM-CFC colonies and cytotoxic drug-induced recruitment of murine | |||
T80502 |
P4pal10
|
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P4pal10为PAR4拮抗剂,能在体内抑制凝血酶介导的小鼠血小板聚集,并显著减少Carrageenan引起的水肿及粒细胞浸润。 | |||
T82924 |
Balugrastim
CG 10639 |
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Balugrastim (CG 10639)为新型长效G-CSF,由重组人血清白蛋白与G-CSF遗传融合制成,适用于乳腺癌研究。 | |||
T76503 |
Defensin NP-3A
|
||
Defensin NP-3A (NP-3A; Corticostatin 1) 是一种人粒细胞肽,具有抗 ACTH 活性。防御素是一种具有杀伤活性的抗菌肽。 | |||
T76908 | Anumigilimab | ||
Anumigilimab (CSL-324) 是一种人源化IgG2a 单抗,靶向人粒细胞集落刺激因子 (G-CSF) 受体。Anumigilimab 可用于炎症部位中性粒细胞数量增加的研究。 | |||
T38384 |
Nexinhib20
|
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Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony-stimulating factor (GM-CSF) and fMLP in isolated human neutrophils (IC50 = 0.33 μM). Nexinhib20 (30 mg/kg) reduces LPS-induced increases in plasma MPO levels, as well as LPS-induced hepatic and renal neutrophil infiltration in a mouse model of endotoxin-induced systemic inflamma... | |||
T73659 |
HLF1-11
|
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HLF1-11,一种人乳铁蛋白衍生肽,是一种广谱抗菌剂。HLF1-11 抑制MPO(human) 的活性。HLF1-11 还使GM-CSF 驱动的单核细胞向巨噬细胞分化,并增强其免疫反应。 | |||
T78328 |
Efbemalenograstim alfa
F 627,Bineuta,Benegrastim |
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Efbemalenograstim alfa(F 627)为重组长效二聚体G-CSF,融合了两个人源G-CSF与人免疫球蛋白G2(hIgG2)-Fc片段,并能有效促进白细胞生成。 | |||
T77172 | Eflapegrastim | ||
Eflapegrastim 是一种人源化IgG4单抗 ,也是一种粒细胞集落刺激因子 (G-CSF)。Eflapegrastim 靶向G-CSF 受体 (c-Fms)。Eflapegrastim 刺激中性粒细胞祖细胞的增殖和分化,维持成熟和功能性中性粒细胞数目稳定。Eflapegrastim 还缩短中性粒细胞减少的持续时间。 | |||
T79149 |
Magmas-IN-1
|
Others | Others |
Magmas-IN-1(compound 9)为针对Magmas的小分子抑制剂(SMMI),后者是线粒体相关粒细胞-巨噬细胞集落刺激因子(GM-CSF)的信号分子,并参与骨髓细胞的GM-CSF诱导基因表达。Magmas-IN-1作用于Magmas,进而调控线粒体功能,并在4 μM浓度下可显著抑制酵母细胞的增殖。 | |||
T63402 |
(S,R)-WT IDH1 Inhibitor 2
|
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(S,R)-WT IDH1 Inhibitor 2 是选择性的、有效的突变型 IDH1抑制剂,能够抑制 R132G (IC50: 2.9 nM)、R132C (IC50: 3.8 nM)、R132H (IC50: 4.6 nM) 和 WT IDH1 (IC50: 46 nM),选择性比 IDH2 高出 100 倍。(S,R)-WT IDH1 Inhibitor 2 具有诱导细胞内 2-HG 减少,髓细胞分化阻滞失效的作用,并且在白血病母细胞和更不成熟的干细胞水平诱导粒细胞分化,可研究用于急性髓系白血病 (AML) 及其他癌症。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03713 |
GM-CSF/CSF2 Protein, Rat, Recombinant (His)
colony stimulating factor 2 (granulocyte-macrophage... |
Rat | HEK293 Cells |
GM-CSF/CSF2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P48750. | |||
TMPY-01650 |
CD131 Protein, Human, Recombinant (His)
CDw131,IL5RB,colony stimulating factor 2 receptor, β, low-af... |
Human | HEK293 Cells |
CD131 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P32927-1. | |||
TMPY-04829 |
G-CSF Protein, Human, Recombinant
G-CSF,colony stimulating factor 3 (granulocyte),集落刺... |
Human | HEK293 Cells |
G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2. | |||
TMPY-05636 |
G-CSF Protein, Mouse, Recombinant
G-CSF,MGI-IG,Csfg,集落刺激因子,colony stimulating factor 3 (gr... |
Mouse | HEK293 Cells |
G-CSF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19 kDa and the accession number is P09920. | |||
TMPY-03858 |
GM-CSF/CSF2 Protein, Human, Recombinant
CSF2,colony stimulating factor 2 (granulocyte-macro... |
Human | HEK293 Cells |
GM-CSF/CSF2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141. | |||
TMPY-02312 |
CSF3R/G-CSFR Protein, Human, Recombinant (His)
CSF3R,GCSFR,colony stimulating factor 3 receptor (granul... |
Human | HEK293 Cells |
CSF3R/G-CSFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is Q99062-1. | |||
TMPY-00750 |
GM-CSF/CSF2 Protein, Human, Recombinant (hFc)
集落刺激因子,CSF2,GM-CSF,colony stimulating factor 2 (granuloc... |
Human | HEK293 Cells |
GM-CSF/CSF2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is P04141. | |||
TMPY-03662 |
GM-CSF/CSF2 Protein, Mouse, Recombinant (His)
GMCSF,MGI-IGM,colony stimulating factor 2 (granulocyte |
Mouse | HEK293 Cells |
GM-CSF/CSF2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.10 kDa and the accession number is P01587. | |||
TMPJ-01465 |
GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)
Colony-Stimulating Factor,CSF2,CSF,Sargramostim,集落刺激因子,Molgr... |
Human | E. coli |
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo... | |||
TMPY-04114 |
GM-CSF/CSF2 Protein, Mouse, Recombinant
MGI-IGM,colony stimulating factor 2 (granulocyte-ma... |
Mouse | HEK293 Cells |
GM-CSF/CSF2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.1 kDa and the accession number is P01587. | |||
TMPY-01065 |
GM-CSFR alpha Protein, Human, Recombinant (His)
GM-CSF-R-α,colony stimulating factor 2 receptor, α, low-affi... |
Human | HEK293 Cells |
GM-CSFR alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P15509-1. | |||
TMPY-04283 |
CD131 Protein, Rat, Recombinant (hFc)
colony stimulating factor 2 receptor, beta, low-affinity ( |
Rat | HEK293 Cells |
CD131 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.1 kDa and the accession number is Q78ZF5. | |||
TMPY-04036 |
GM-CSF/CSF2 Protein, Rat, Recombinant (hFc)
集落刺激因子,colony stimulating factor 2 (granulocyte-mac... |
Rat | HEK293 Cells |
GM-CSF/CSF2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is P48750. | |||
TMPY-05236 |
GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated
CSF2,GMCSF,GM-CSF,集落刺激因子,colony stimulating factor 2 (gr... |
Human | HEK293 Cells |
GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141. | |||
TMPJ-00091 |
G-CSF Protein, Mouse, Recombinant (His)
Csf3,G-CSF,Granulocyte colony-stimulating factor,集落... |
Mouse | HEK293 Cells |
Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of ... | |||
TMPY-00814 |
CSF3R/G-CSFR Protein, Human, Recombinant (hFc)
G-CSF R,GCSFR,CD114,CSF3R,colony stimulating factor 3 recept... |
Human | HEK293 Cells |
CSF3R/G-CSFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.3 kDa and the accession number is Q99062-1. | |||
TMPY-02466 |
GM-CSF/CSF2 Protein, Human, Recombinant (His)
colony stimulating factor 2 (granulocyte-macrophage... |
Human | HEK293 Cells |
GM-CSF/CSF2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P04141. | |||
TMPY-00813 |
G-CSF Protein, Human, Recombinant (hFc)
CSF3OS,C17orf33,colony stimulating factor 3 (granulocyte... |
Human | HEK293 Cells |
G-CSF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P09919-2. | |||
TMPY-03631 |
GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc)
GMCSF,Csfgm,集落刺激因子,colony stimulating factor 2 (granuloc... |
Mouse | HEK293 Cells |
GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01587. | |||
TMPY-00816 |
GM-CSFR alpha Protein, Human, Recombinant (hFc)
CSF2RAX,CSF2R,CD116,CSF2RY,GM-CSF-R-α,GM-CSF-R-alpha,GM-CSF ... |
Human | HEK293 Cells |
GM-CSFR alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.2 kDa and the accession number is P15509-1. | |||
TMPJ-01060 |
CXCL6 Protein, Human, Recombinant (His)
SCYB6,Chemokine Alpha 3,CKA-3,GCP2,GCP-2,C-X-C Motif Chemoki... |
Human | HEK293 Cells |
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell... | |||
TMPY-01850 |
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC119875,carcinoembryonic antigen ... |
Human | HEK293 Cells |
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... | |||
TMPJ-01466 |
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC... |
Human | HEK293 Cells |
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF... | |||
TMPJ-01467 |
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
Oncostatin-M,OSM |
Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac... | |||
TMPH-01047 |
CEACAM4 Protein, Human, Recombinant (His)
CEACAM4,CGM7,Carcinoembryonic antigen CGM7,CEA cell adhesion... |
Human | P. pastoris (Yeast) |
Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles. CEACAM4 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.7 kDa and the accession number is O75871. | |||
TMPK-00876 |
G-CSFR/CD114 Protein, Mouse, Recombinant (His)
CD114,G CSF R,G-CSF-R,G-CSF R,CSF3R,GCSFR,Csfgr |
Mouse | HEK293 Cells |
The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires the recruitment of cytosolic protein tyrosine kinases (PTKs) to transduce its signal. | |||
TMPH-01046 |
CEACAM4 Protein, Human, Recombinant (E. coli, His)
Carcinoembryonic antigen-related cell adhesion molecule 4,CE... |
Human | E. coli |
Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles. CEACAM4 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.7 kDa and the accession number is O75871. | |||
TMPK-00144 |
CEACAM3 Protein, Human, Recombinant (hFc)
CEACAM3,CGM1,CEA,CD66d |
Human | HEK293 Cells |
The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac. | |||
TMPK-01323 |
CEACAM1 Protein, Canine, Recombinant (His)
CEACAM1,BGP1,BGP,CD66a,BGPI |
Canine | HEK293 Cells |
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM-1) is the major antigen of the CD66 cluster of granulocyte differentiation antigens. The present study aimed to assess the biological function of CEACAM-1 on the growth of human colorectal cancer (CRC) cells in vitro. CEACAM1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43.62 kDa and the accession number is XP_038509497.1. | |||
TMPK-00869 |
CEACAM1 Protein, Mouse, Recombinant (aa 35-428, His)
BGP,CEACAM1,BGP1,CD66a,BGPI |
Mouse | HEK293 Cells |
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM-1) is the major antigen of the CD66 cluster of granulocyte differentiation antigens. The present study aimed to assess the biological function of CEACAM-1 on the growth of human colorectal cancer (CRC) cells in vitro. CEACAM1 Protein, Mouse, Recombinant (aa 35-428, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 44.7 kDa and the accession number is P31809-1. | |||
TMPJ-00231 |
LRG1 Protein, Human, Recombinant (hFc & His)
LRG and LRG1,Leucine-rich alpha-2-glycoprotein,Leucine-rich ... |
Human | HEK293 Cells |
LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid. | |||
TMPY-01299 |
GMF gamma/GMFG Protein, Human, Recombinant (His)
glia maturation factor, γ,glia maturation factor, gamma,GMF-... |
Human | E. coli |
The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells. GMFG expression independently predicts poorer prognosis in patients with EOC. Ectopic overexpression of GMFG contributes to the malignant biological behavior of ovarian cancer cells. | |||
TMPY-02577 |
NAMPT Protein, Human, Recombinant (His & GST)
VISFATIN,PBEF,PBEF1,1110035O14Rik,VF,nicotinamide phosphorib... |
Human | Baculovirus Insect Cells |
Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is... | |||
TMPJ-00080 |
IL-11 Protein, Human, Recombinant (P. pastoris)
白细胞介素,Oprelvekin,Adipogenesis Inhibitory Factor,白介素,IL11,AGI... |
Human | P. pastoris (Yeast) |
Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its recepto... | |||
TMPY-04421 |
FES Protein, Human, Recombinant (His & GST)
FPS,FES proto-oncogene, tyrosine kinase |
Human | Baculovirus Insect Cells |
Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and oneSH2 domain. FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. FES is observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-6. T... |