Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Acetyl-D-cysteine 具有抗氧化活性,机制是通过与巯基反应清除ROS。N-Acetyl-D-cysteine 不能进入谷胱甘肽代谢途径。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 266 | 现货 | ||
10 mg | ¥ 378 | 现货 | ||
25 mg | ¥ 622 | 现货 | ||
50 mg | ¥ 747 | 现货 | ||
100 mg | ¥ 1,230 | 现货 | ||
500 mg | ¥ 2,970 | 现货 |
产品描述 | N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group. |
体外活性 | Consistent with the known stereoselectivity of many biological processes, the unnatural D isomer of N-acetylcysteine failed to increase hepatic glutathione. Liver concentrations remained similar to control suggesting that the D isomer was unable to increase the rate of glutathione synthesis. The D isomer further differed from its L enantiomer in failing to increase the plasma concentration and the urinary excretion of inorganic sulfate. Congruent with these observations, much more N-acetyl-D-cysteine (47% of dose) was recovered unchanged in 24 hr urine than N-acetyl-L-cysteine (6.1% of dose)[2]. |
分子量 | 163.19 |
分子式 | C5H9NO3S |
CAS No. | 26117-28-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 250 mg/mL (1531.96 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 6.1278 mL | 30.6391 mL | 61.2783 mL | 153.1957 mL |
5 mM | 1.2256 mL | 6.1278 mL | 12.2557 mL | 30.6391 mL | |
10 mM | 0.6128 mL | 3.0639 mL | 6.1278 mL | 15.3196 mL | |
20 mM | 0.3064 mL | 1.532 mL | 3.0639 mL | 7.6598 mL | |
50 mM | 0.1226 mL | 0.6128 mL | 1.2256 mL | 3.0639 mL | |
100 mM | 0.0613 mL | 0.3064 mL | 0.6128 mL | 1.532 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
N-Acetyl-D-cysteine 26117-28-2 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species murine embryonic NAcetylDcysteine GSH glutathione fibroblast Inhibitor N Acetyl D cysteine inhibit MEF inhibitor