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77

抑制剂 & 化合物

25

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Cat. No.	Product Name	Target	Signaling Pathways
T11669	IR415	HBV	Microbiology/Virology
	IR415 选择性地与 HBx 相互作用 (Kd=2 nM) 并阻断 HBV 介导的 RNAi 抑制，逆转 HBx 蛋白对 Dicer 核糖核酸内切酶活性的抑制作用。IR415 具有抗 HBV 的活性。
T16276	NBD-556	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	NBD-556是一种 CD4 模拟物，识别 HIV-1 包膜蛋白 gp120 并诱导 gp120 重组，类似于 CD4 结合，可阻断 gp120-CD4 的相互作用。
T6515	Go6976 Gö 6976	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Go6976是蛋白激酶C (PKC)的小分子抑制剂。Go6976作为研究PKC 在各种生理和病理生理过程中的作用的工具，广泛应用于生物医学研究。
T12399	Peldesine BCX 34	Nucleoside Antimetabolite/Analog; HIV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Peldesine (BCX 34) 是一种有效的、竞争性的、可逆的和口服活性的嘌呤核苷磷酸化酶抑制剂。 Peldesine 抑制 T 细胞增殖，IC50 为 800 nM。 Peldesine 可用于皮肤 T 细胞淋巴瘤、牛皮癣和 HIV 感染的研究。
T0134	Imiquimod 咪喹莫特,R 837,S-26308	SARS-CoV; TLR; Autophagy; HSV	Autophagy; Immunology/Inflammation; Microbiology/Virology
	Imiquimod (R 837) 是一种免疫反应修饰剂，可作为 toll 样受体7 激动剂。它有抗病毒和抗肿瘤作用，可研究外生殖器、肛周疣、癌症和 COVID-19。
T0994	Ketotifen fumarate HC 20511 fumarate,富马酸酮替芬	PDE; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Ketotifen fumarate (HC 20511 fumarate) 是组胺 H1 受体和炎症介质释放的环七噻吩阻滞剂。
T1602	Valproic acid sodium salt 丙戊酸钠,Sodium Valproate	Mitophagy; Gamma-secretase; HIV Protease; GABA Receptor; HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome; Stem Cells
	Valproic acid sodium salt (Sodium Valproate) 是一种HDAC 抑制剂，可抑制HDAC1的活性，诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、偏头痛和双相情感障碍等。
T6474	Divalproex Sodium Valproate semisodium,Epival,双丙戊酸钠	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Divalproex Sodium (Valproate semisodium) 结合并抑制 γ-氨基丁酸 (GABA) 转氨酶，其抗惊厥活性可通过增加 GABA 脑浓度和抑制分解 GABA 或阻止 GABA 再摄取到神经胶质和神经末梢的酶来发挥。它也是一种 HDAC 抑制剂。由丙戊酸钠和丙戊酸组成，具有抗惊厥和抗癫痫活性。 Divalproex 还可以通过抑制电压敏感的钠通道来抑制重复的神经元放电。
T17190	U18666A	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	U18666A 是一种细胞渗透性药物，是一种胆固醇合成和转运抑制剂，抑制埃博拉病毒，登革热病毒和人类丙型肝炎病毒的复制。
T67854	BAS 00489700	Others	Others
	BAS 00489700是一种N-UTR 相互作用抑制剂。BAS 00489700抑制培养细胞中的病毒复制。
T8886	NITD-2	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	NITD-2 是一种登革病毒 (DENV) 聚合酶抑制剂，可抑制 DENV RdRp 介导的 RNA 延伸。
T7366	NGI-1 ML414	Virus Protease	Microbiology/Virology
	NGI-1 (ML414) 是一种可渗透细胞的寡糖转移酶 (OST) 抑制剂，直接靶向和阻断 OST 催化亚基 STT3A 和 STT3B 的功能，可有效降低病毒感染性而不影响细胞活力。
TP1735L	Influenza HA 126-138 acetate Influenza HA 126-138 acetate(207349-63-1 free base)	Others	Others
	Influenza HA 126-138 acetate 是一种流感病毒血凝素 (HA) 肽乙酸盐，包含氨基酸 126-138。它诱导胸腺和外周 T 细胞凋亡。
T26674	AT-130 AT 130	HBV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	AT-130 是一种苯基丙烯酰胺衍生物，是乙型肝炎病毒复制的非核苷抑制剂。它抑制病毒 DNA 的合成，EC50为 0.13 μM。
TP1809	TAT	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	TAT 源自人免疫缺陷病毒的转录反式激活因子，是一种细胞穿透肽。它可以增加异源蛋白质的产量和溶解度。
T12575	Unesbulin PTC596	Apoptosis; BMI-1	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Unesbulin (PTC596) 是一种口服有效和选择性的 B 细胞特异性莫洛尼氏鼠白血病病毒整合位点 1 抑制剂。它在急性髓细胞白血病细胞中可下调 MCL-1 并诱导不依赖 p53 的线粒体凋亡，具有抗白血病作用。
T15704	Lagociclovir MIV-210	HBV	Microbiology/Virology
	Lagociclovir (MIV-210) 是一种核苷类似物，是一种可用治疗 HBV82的抗病毒化合物，可抑制野生型乙型肝炎病毒 (HBV) 在永久表达 HBV 的人肝癌细胞系中的复制。
T6229	Daclatasvir Daklinza,达卡他韦,EBP 883,达拉他韦,BMS-790052	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Daclatasvir (EBP 883) 是一种高度选择性的 HCV NS5A 抑制剂，EC50 为 9-50 pM，适用于细胞培养中的多种 HCV 复制子基因型和 JFH-1 基因型 2a 感染性病毒。
T27527	HBF-0259 HBF 0259	Antiviral	Immunology/Inflammation
	HBF-0259 是有效的乙型肝炎病毒表面抗原分泌选择性抑制剂，在 HepG2.2.15 细胞中的 EC50为 1.5 μM。
T77059	Leronlimab PRO 140	CCR	Immunology/Inflammation; Microbiology/Virology
	Leronlimab (PRO 140) 是一种人源化 IgG4 抗 CCR5 单克隆抗体。leronlimumab 具有抗 HIV 病毒活性和抗肿瘤活性，抑制 CCR 介导的 HIV-1 病毒和小鼠肿瘤模型中癌细胞转移。Leronlimab 可用于研究 HIV 非酒精性脂肪性肝炎 (NASH) 和乳腺癌。
T11449L	Golotimod Gamma-D-glutamyl-L-tryptophan,SCV 07	Antibiotic	Microbiology/Virology
	Golotimod (SCV 07) 是一种具有抗菌活性的二肽，具有免疫调节活性，能显著提高抗结核治疗的疗效，诱导胸腺和脾脏细胞增殖，调节巨噬细胞功能，抑制 STAT3 信号传导。Golotimod 可用于研究复发性生殖器单纯疱疹病毒 2 （HSV-2）感染和口腔黏膜炎。
T38960	QL-X-138	Virus Protease; MNK; BTK	Angiogenesis; MAPK; Microbiology/Virology; Tyrosine Kinase/Adaptors
	QL-X-138 是一种强效的选择性 BTK和 MNK 双激酶抑制剂，与 BTK 具有共价结合，与 MNK 具有非共价结合。QL-X-138 对 BTK、MNK1 和 MNK2 激酶的 IC 50 s 分别为 9.4 nM、107.4 nM 和 26 nM。QL-X-138 对登革病毒 2 具有抑制作用，其 IC 50 为 3.5 μM。QL-X-138 可用于 B 细胞恶性肿瘤的研究。
TP2402	Peptide VF13N Epitope VF13N
	Peptide VF13N is a synthetic rabies virus glycoprotein T helper cell epitope.
T71996	VU0621623
	VU0621623 is an arenavirus multiplication inhibitor which blocks lymphocytic choriomeningitis virus (LCMV) cell entry.
T30443	BIBX 1382 Dihydrochloride Falnidamol dihydrochloride,BIBX1382 Dihydrochloride,BIBX-1382 Dihydrochloride,BIBX 1382 2HCl,Falnidamol 2HCl
	BIBX 1382 Dihydrochloride prevents Lassa and Ebola virus glycoprotein-dependent cells from entering the body. It can be used as a tool to understand conserved virus-host interactions and suggests that host cell kinases may be targets for broad-spectrum th
T27498	GSK983 GSK-983,GSK 983
	GSK983, a potent broad-spectrum antiviral, blocks cell proliferation and dengue virus replication by inhibiting the pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase (DHODH).
T25256	Pitstop1 Clathrin inhibitor 1,Clathrin-inhibitor-1,Clathrin IN 1
	Clathrin-IN-1 is a selective clathrin inhibitor that acts by addressing clathrin function in cell physiology with potential applications as an inhibitor of virus and pathogen entry and as a modulator of cell signaling.
T60970	Caprochlorone
	Caprochlorone 对正痘病毒具有抗病毒活性，可以降低被感染的小鼠肺部中流感病毒的滴度。Caprochlorone 可以抑制病毒穿透细胞，并且延迟新形成的病毒从细胞释放。
TP1776	HIV-1 TAT 48-60
	HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. This is one of the cell-penetrating peptides generated from the human immunodeficient virus -1 Tat protein residue 48-60.
TP1553	Rabies Virus Glycoprotein TFA
	Rabies Virus Glycoprotein (TFA) is a kind of by the Rabies Virus Glycoprotein 29 - amino acid derived cell penetrating peptides, it can pass the blood brain barrier (BBB) into the brain cells.
T4377L	Pimodivir HCl Pimodivir hydrochloride hemihydrate,Pimodivir hydrochloride
	Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. The cell-based EC50 for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay. VX-787 is active against a diverse
TP1407	TAT TFA (191936-91-1 free base) TAT TFA
	TAT TFA (YGRKKRRQRRR) is derived from human immunodeficiency virus (hiv-1) transcription reverse activator TAT, is a cell penetrating peptide.
T82592	DEC-RVRK-CMK Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
	DEC-RVRK-CMK为一种小型合成抗病毒化合物，具不可逆性及细胞渗透性，作为竞争性弗林蛋白酶抑制剂，该化合物对寨卡病毒(ZIKV)和日本脑炎病毒(JEV)显示出显著的抗病毒活性。
T76555	Rabies Virus Matrix Protein Fragment(RV-MAT)
	Rabies VirusMatrix ProteinFragment (RV-MAT)为多肽类化合物，靶向细胞表面乙酰胆碱受体(AChR)。
T76382	Hemagglutinin (48-68)
	Hemagglutinin (48-68) 为流感病毒血凝素的48至68片段，能够诱导肽特异性T细胞克隆增殖。
T69187	Cenicriviroc Sulfone
	Cenicriviroc Sulfone is a derivative of Cenicriviroc which is an experimental drug candidate for the treatment of HIV infection. It is an inhibitor of CCR2 and CCR5 receptors allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell.
T27668	JNJ-2408068 R170591,R 170591,HE066500,R-170591,HE-066500,HE 066500
	JNJ-2408068 is an inhibitor of respiratory syncytial virus (RSV). JNJ-2408068 exhibited potent antiviral activity with EC50 of 2.1 nM. A similar inhibitory effect was observed in a RSV-mediated cell fusion assay (EC50= 0.9 nM). JNJ-2408068 interferes with
TP1520	Hepatitis B Virus Core (128-140) Hepatitis B Virus Core 128-140
	The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during the cell cycle.
T27768	L-696229 L696,229,L-696,229,L 696229,L696229,L 696,229
	L-696229 is a specific inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). L-696229 inhibited RT activity in a mutually exclusive manner with respect to either phosphonoformate or azidothymidine triphosphate and was a weak
T70207	Pimodivir tosylate
	Pimodivir, also known as VX-787, JNJ-872, is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. VX-787 binds the cap-binding domain of the PB2 subunit with a KD (dissociation constant) of 24 nM as determined by isothermal titration calorimetry (ITC). The cell-based EC50 (the concentration of compound that ensures 50% cell viability of an uninfected control) for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay...
TP2191	VSV-G Peptide	Others	Others
	VSV-G is a vesicular stomatitis virus G (VSV-G) protein fragment. VSV-G protein is commonly used in biomedical research to pseudotype retroviral and lentiviral vectors, conveying the ability to transduce a broad range of mammalian cell types with genes of
T35771	Destruxin B2
	Destruxin B2 is a cyclic hexadepsipeptide mycotoxin that has been found in M. anisopliae and has antiviral, insecticidal, and phytotoxic activities.1,2,3 It inhibits secretion of hepatitis B virus surface antigen (HBsAg) by Hep3B cells expressing hepatitis B virus (HBV) DNA (IC50 = 1.3 μM).1 Destruxin B2 is toxic to Sf9 insect cells in an electric cell-substrate impedance sensing (ECIS) test with a 50% inhibitory concentration (ECIS50) value of 92 μM.4 It is also phytotoxic to B. napus leaves.3 ...
T73283	HBV-IN-32
	HBV-IN-31 是一种有效的共价闭合环状 DNA (cccDNA) 抑制剂。HBV-IN-31 具有抗HBV 活性，对 HBsAg 的 IC50值为 0.14 µM。HBV-IN-31 抑制细胞生长。
T75758	TAT TFA
	TAT TFA (YGRKKRRQRRR)，一个来源于人免疫缺陷病毒 (HIV-1) 转录反式激活因子 (TAT) 的细胞穿透肽，能够提高异源蛋白的产量与溶解度。
TP1752	GP(33-41)
	GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2Db molecules at the RMA-S (Db Kb) cell surface with a SC50 of 344 nM. GP33-41 Epitopeis a strong agonist of CD8 T cells
T72864	Perillic acid 紫苏酸
	Perillic acid 是 Perillyl alcohol 的代谢物。Perillic acid 诱导肺癌细胞周期阻滞和凋亡 (apoptosis)。Perillic acid 具有抗HSV-1和免疫调节活性。
T62932	NS2B/NS3-IN-2
	NS2B/NS3-IN-2 是一种有效的、共价的登革病毒 (DENV)NS2B/NS3 抑制剂 (IC50: 6.0 nM，Ki: 0.66 μM)。NS2B/NS3-IN-2 可以明显提高细胞存活率，且没有细胞毒性。
T22838	hemagglutinin (332-340) [Influenza A virus]	Others	Others
	Influenza hemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. Influenza hemagglutinin proteins bind to cells w
T73156	LabMol-301
	LabMol-301 抑制NS5 RdRp 和NS2B-NS3pro 的活性 (IC50分别为 0.8 和 7.4 μM)。LabMol-301 具有细胞保护作用并阻止寨卡病毒 (ZIKV) 诱导的细胞死亡。
T78618	NSC 288387	Virus Protease	Microbiology/Virology
	NSC 288387是泛黄病毒MTase的抑制剂，能与SAM结合袋发生作用。该化合物对ZIKV表现出抑制活性，IC50值为0.2 μM，并能够抑制细胞培养中的病毒复制。

化合物

Cat.No: T11669

Target: HBV

Cat.No: T16276

Target: HIV Protease

Cat.No: T6515

Synonym: Gö 6976

Target: PKC

Cat.No: T12399

Synonym: BCX 34

Target: Nucleoside Antimetabolite/Analog, HIV Protease

Cat.No: T0134

Synonym: 咪喹莫特,R 837,S-26308

Target: SARS-CoV, TLR, Autophagy, HSV

Ketotifen fumarate

Cat.No: T0994

Synonym: HC 20511 fumarate,富马酸酮替芬

Target: PDE, Histamine Receptor

Valproic acid sodium salt

Cat.No: T1602

Synonym: 丙戊酸钠,Sodium Valproate

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, HDAC, Autophagy

Divalproex Sodium

Cat.No: T6474

Synonym: Valproate semisodium,Epival,双丙戊酸钠

Target: HDAC

Cat.No: T17190

Target: Others, HCV Protease

Cat.No: T67854

Target: Others

Cat.No: T8886

Target: DNA/RNA Synthesis

Cat.No: T7366

Synonym: ML414

Target: Virus Protease

Influenza HA 126-138 acetate

Cat.No: TP1735L

Synonym: Influenza HA 126-138 acetate(207349-63-1 free base)

Target: Others

Cat.No: T26674

Synonym: AT 130

Target: HBV, DNA/RNA Synthesis

Cat.No: TP1809

Target: HIV Protease

Cat.No: T12575

Synonym: PTC596

Target: Apoptosis, BMI-1

Cat.No: T15704

Synonym: MIV-210

Target: HBV

Cat.No: T6229

Synonym: Daklinza,达卡他韦,EBP 883,达拉他韦,BMS-790052

Target: HCV Protease

Cat.No: T27527

Synonym: HBF 0259

Target: Antiviral

Cat.No: T77059

Synonym: PRO 140

Target: CCR

Cat.No: T11449L

Synonym: Gamma-D-glutamyl-L-tryptophan,SCV 07

Target: Antibiotic

Cat.No: T38960

Target: Virus Protease, MNK, BTK

Cat.No: TP2402

Synonym: Epitope VF13N

Cat.No: T71996

BIBX 1382 Dihydrochloride

Cat.No: T30443

Synonym: Falnidamol dihydrochloride,BIBX1382 Dihydrochloride,BIBX-1382 Dihydrochloride,BIBX 1382 2HCl,Falnidamol 2HCl

Cat.No: T27498

Synonym: GSK-983,GSK 983

Cat.No: T25256

Synonym: Clathrin inhibitor 1,Clathrin-inhibitor-1,Clathrin IN 1

Cat.No: T60970

HIV-1 TAT 48-60

Cat.No: TP1776

Rabies Virus Glycoprotein TFA

Cat.No: TP1553

Cat.No: T4377L

Synonym: Pimodivir hydrochloride hemihydrate,Pimodivir hydrochloride

TAT TFA (191936-91-1 free base)

Cat.No: TP1407

Synonym: TAT TFA

Cat.No: T82592

Synonym: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone

Rabies Virus Matrix Protein Fragment(RV-MAT)

Cat.No: T76555

Hemagglutinin (48-68)

Cat.No: T76382

Cenicriviroc Sulfone

Cat.No: T69187

Cat.No: T27668

Synonym: R170591,R 170591,HE066500,R-170591,HE-066500,HE 066500

Hepatitis B Virus Core (128-140)

Cat.No: TP1520

Synonym: Hepatitis B Virus Core 128-140

Cat.No: T27768

Synonym: L696,229,L-696,229,L 696229,L696229,L 696,229

Pimodivir tosylate

Cat.No: T70207

Cat.No: TP2191

Target: Others

Cat.No: T35771

Cat.No: T73283

Cat.No: T75758

Cat.No: TP1752

Cat.No: T72864

Synonym: 紫苏酸

Cat.No: T62932

hemagglutinin (332-340) [Influenza A virus]

Cat.No: T22838

Target: Others

Cat.No: T73156

Cat.No: T78618

Target: Virus Protease

Cat. No.	Product Name	Target	Signaling Pathways
T5S0055	Chelidonine Helidonine,Khelidonin,白屈菜碱,Stylophorin	Apoptosis; Others; Influenza Virus	Apoptosis; Microbiology/Virology; Others
	Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱，有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。
T7064	Valproic Acid Sodium valproate,2-Propylpentanoic Acid,丙戊酸,VPA,Depakine,2-Propylvaleric Acid	Mitophagy; Gamma-secretase; HIV Protease; GABA Receptor; Sodium Channel; HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome; Stem Cells
	Valproic Acid (2-Propylpentanoic Acid) 是一种 HDAC 抑制剂，可抑制 HDAC1 活性，诱导 HDAC2 降解，具有口服活性。Valproic Acid 可以用于癫痫和躁郁症的研究。
T14304	Aphidicolin	Others	Others
	Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA
T1506	Vidarabine Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A	Nucleoside Antimetabolite/Analog; Tyrosine Kinases; DNA/RNA Synthesis; Antibiotic; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Vidarabine (Adenine Arabinoside) 是从链霉菌分离的核苷类抗生素，能抗单纯性疱疹和水痘-带状疱疹病毒。它对 HSV-1 和 HSV-2 的 IC50值分别为 9.3 μg/ml 和 11.3 μg/ml。
TN1956	Mulberrofuran G	Phosphatase; HBV; Glucosidase	Metabolism; Microbiology/Virology
	Mulberrofuran G分离自自 Morus alba L.，具有抗乙型肝炎病毒活性，可保护缺血损伤诱导的细胞死亡。Mulberrofuran G 是一种 PTP1B 和 α-葡萄糖苷酶的双重抑制剂，可用于研究阿尔茨海默症。
TN3048	4-Methoxycinnamaldehyde p-Methoxycinnamaldehyde	RSV	Microbiology/Virology
	4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) 是 Agastache rugosa 的一种活性成分。4-Methoxycinnamaldehyde 对人喉癌细胞系中的呼吸道合胞病毒 (RSV) 具有细胞保护活性，有助于控制 RSV 感染诱发的疾病，IC50 约为 0.055 μg/mL。
T75643	Isoxanthohumol	HSV	Microbiology/Virology
	Isoxanthohumol 是一种从啤酒花和啤酒中提取的一种前黄酮类化合物，对几种人类癌细胞株具有抗增殖活性。Isoxanthohumol对肿瘤细胞肺转移灶的转移或侵袭有抑制作用。Isoxanthohumol具有抗病毒活性，对疱疹病毒（HSV1和HSV2）和牛病毒性腹泻病毒（BVDV）具有抑制作用。
T5S2343	Acetylshikonin 乙酰紫草素,Acetyl shikonin	Others; P450; AChE	Metabolism; Neuroscience; Others
	Acetylshikonin 来源于紫草根，具有抗癌、抗炎作用。它是一种 AChE 抑制剂，具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂，对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
TN4455	Lucialdehyde B	Integrase; HSV	Microbiology/Virology
	Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
TN4109	Ganolucidic acid A	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of 20-90 microM.
T15703	Lactimidomycin	Others	Others
	Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferative effect on tumor cell lines. It i
TN3528	Bonducellpin D	Antifection	Microbiology/Virology
	Bonducellpin D may show inhibitory activities on the Para3 virus. It also exhibits moderate activity against four tested human cancer cell lines, HepG-2, K562, HeLa, and Du145.
TN5133	3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone	HIV Protease; Topoisomerase	DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. It exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity.
T3930	Taraxerol acetate 醋酸蒲公英霜,Taraxeryl acetate	Phosphatase; HSV	Metabolism; Microbiology/Virology
	Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activity, could be attributed due to PTP
TN3559	Cabraleahydroxylactone	HSV	Microbiology/Virology
	Cabraleahydroxylactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line.It shows antiviral activity against herpes simplex virus type-1 with an IC50 value of 3.20 ug/mL, in comparison with the standard acyclovir (IC50=1.90ug/mL).
TN3925	Eichlerianic acid	HSV	Microbiology/Virology
	Eichlerianic acid is a trypanocidal compound with an IC50 value of 10 mg/mL. Eichlerianic acid may have antiviral activity against Herpes simplex virus types I and II in vitro. Eichlerianic acid shows weak cytotoxicity (IC50 6.87 to >40 μM) against human cancer cell (HL-60, SMMC-7721, A-549, MCF-7 and SW480).
TN4404	Ladanein	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities against K562, K562R (imatinib-resistant), and 697 human leukemia cell lines.
TN4587	Mulberrofuran C	HSV	Microbiology/Virology
	Mulberrofuran C shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 0.41 ± 0.48 uM ; it also shows protective effects on glutamate-induced cell death with the EC50 value of 16.50 ± 7.82 uM. Mulberrofuran C has antiviral effects against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2).
TN3438	Arborinine	HCV Protease; Antifection	Microbiology/Virology; Proteases/Proteasome
	Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0.7 ug/ml. Arborinine shows antifeedant activity against Spodoptera frugiperda. Arborinin shows
T70355	Flutimide
	Flutimide是一种针对流感病毒核酸内切酶的选择性抑制剂，具有3 μM的IC50值，表现出细胞培养中的抗病毒活性，适用于流感等急性传染性呼吸道疾病的研究。
T79976	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside	HBV	Microbiology/Virology
	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside 作为一种抗HBV剂，在Hep G2.2.15细胞系上能够抑制HBsAg和HBeAg的分泌，其IC50值分别约为1.67 mM和>2.15 mM。
TN4592	Murrangatin	IL Receptor; TNF; COX; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line,
TN4140	Glochidiol	Others	Others
	Glochidiol exhibits strong inhibitory effects against all three human tumor cell lines (MCF-7, NCI-H-460 and SF-268), it exerts its antiproliferative activity through the involvement of apoptosis. It exhibits a strong inhibitory effect on mouse skin tumor
TN2977	3-O-trans-p-Coumaroyltormentic acid	Caspase; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3beta-O-cis-p-Coumaroyltormentic acid, an...
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ...

天然产物

Cat.No: T5S0055

Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Cat.No: T7064

Synonym: Sodium valproate,2-Propylpentanoic Acid,丙戊酸,VPA,Depakine,2-Propylvaleric Acid

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy

Cat.No: T14304

Target: Others

Cat.No: T1506

Synonym: Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A

Target: Nucleoside Antimetabolite/Analog, Tyrosine Kinases, DNA/RNA Synthesis, Antibiotic, HSV

Mulberrofuran G

Cat.No: TN1956

Target: Phosphatase, HBV, Glucosidase

4-Methoxycinnamaldehyde

Cat.No: TN3048

Synonym: p-Methoxycinnamaldehyde

Target: RSV

Cat.No: T75643

Target: HSV

Cat.No: T5S2343

Synonym: 乙酰紫草素,Acetyl shikonin

Target: Others, P450, AChE

Cat.No: TN4455

Target: Integrase, HSV

Ganolucidic acid A

Cat.No: TN4109

Target: HIV Protease

Cat.No: T15703

Target: Others

Cat.No: TN3528

Target: Antifection

3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone

Cat.No: TN5133

Target: HIV Protease, Topoisomerase

Taraxerol acetate

Cat.No: T3930

Synonym: 醋酸蒲公英霜,Taraxeryl acetate

Target: Phosphatase, HSV

Cabraleahydroxylactone

Cat.No: TN3559

Target: HSV

Eichlerianic acid

Cat.No: TN3925

Target: HSV

Cat.No: TN4404

Target: HCV Protease

Mulberrofuran C

Cat.No: TN4587

Target: HSV

Cat.No: TN3438

Target: HCV Protease, Antifection

Cat.No: T70355

Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside

Cat.No: T79976

Target: HBV

Cat.No: TN4592

Target: IL Receptor, TNF, COX, Prostaglandin Receptor

Cat.No: TN4140

Target: Others

3-O-trans-p-Coumaroyltormentic acid

Cat.No: TN2977

Target: Caspase, Antifection

Cat.No: T35779

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