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Search Results for " granulocyte-macrophage "

Targets Recommended: c-Fms

4

抑制剂 & 化合物

17

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T80585	Anti-Mouse GM-CSF Antibody (MP1-22E9)	c-Fms	Tyrosine Kinase/Adaptors
	Anti-MouseGM-CSFAntibody 为特异性针对小鼠GM-CSF的IgG2a类免疫球蛋白抗体，由大鼠血清中提取。
T38384	Nexinhib20
	Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony-stimulating factor (GM-CSF) and fMLP in isolated human neutrophils (IC50 = 0.33 μM). Nexinhib20 (30 mg/kg) reduces LPS-induced increases in plasma MPO levels, as well as LPS-induced hepatic and renal neutrophil infiltration in a mouse model of endotoxin-induced systemic inflamma...
T73659	HLF1-11
	HLF1-11，一种人乳铁蛋白衍生肽，是一种广谱抗菌剂。HLF1-11 抑制MPO(human) 的活性。HLF1-11 还使GM-CSF 驱动的单核细胞向巨噬细胞分化，并增强其免疫反应。
T79149	Magmas-IN-1	Others	Others
	Magmas-IN-1（compound 9）为针对Magmas的小分子抑制剂（SMMI），后者是线粒体相关粒细胞-巨噬细胞集落刺激因子（GM-CSF）的信号分子，并参与骨髓细胞的GM-CSF诱导基因表达。Magmas-IN-1作用于Magmas，进而调控线粒体功能，并在4 μM浓度下可显著抑制酵母细胞的增殖。

化合物

Anti-Mouse GM-CSF Antibody (MP1-22E9)

Cat.No: T80585

Target: c-Fms

Cat.No: T38384

Cat.No: T73659

Cat.No: T79149

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03713	GM-CSF/CSF2 Protein, Rat, Recombinant (His) colony stimulating factor 2 (granulocyte-macrop...	Rat	HEK293 Cells
	GM-CSF/CSF2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P48750.
TMPY-01650	CD131 Protein, Human, Recombinant (His) CDw131,IL5RB,colony stimulating factor 2 receptor, β, low-af...	Human	HEK293 Cells
	CD131 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P32927-1.
TMPY-03858	GM-CSF/CSF2 Protein, Human, Recombinant CSF2,colony stimulating factor 2 (granulocyte-m...	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141.
TMPY-00750	GM-CSF/CSF2 Protein, Human, Recombinant (hFc) 集落刺激因子,CSF2,GM-CSF,colony stimulating factor 2 (granuloc...	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is P04141.
TMPY-03662	GM-CSF/CSF2 Protein, Mouse, Recombinant (His) GMCSF,MGI-IGM,colony stimulating factor 2 (granulocyte	Mouse	HEK293 Cells
	GM-CSF/CSF2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.10 kDa and the accession number is P01587.
TMPY-04114	GM-CSF/CSF2 Protein, Mouse, Recombinant MGI-IGM,colony stimulating factor 2 (granulocyte-	Mouse	HEK293 Cells
	GM-CSF/CSF2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.1 kDa and the accession number is P01587.
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) Colony-Stimulating Factor,CSF2,CSF,Sargramostim,集落刺激因子,Molgr...	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo...
TMPY-01065	GM-CSFR alpha Protein, Human, Recombinant (His) GM-CSF-R-α,colony stimulating factor 2 receptor, α, low-affi...	Human	HEK293 Cells
	GM-CSFR alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P15509-1.
TMPY-04283	CD131 Protein, Rat, Recombinant (hFc) colony stimulating factor 2 receptor, beta, low-affinity (	Rat	HEK293 Cells
	CD131 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.1 kDa and the accession number is Q78ZF5.
TMPY-04036	GM-CSF/CSF2 Protein, Rat, Recombinant (hFc) 集落刺激因子,colony stimulating factor 2 (granulocyte-	Rat	HEK293 Cells
	GM-CSF/CSF2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is P48750.
TMPY-05236	GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated CSF2,GMCSF,GM-CSF,集落刺激因子,colony stimulating factor 2 (gr...	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141.
TMPY-02466	GM-CSF/CSF2 Protein, Human, Recombinant (His) colony stimulating factor 2 (granulocyte-macrop...	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P04141.
TMPY-03631	GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc) GMCSF,Csfgm,集落刺激因子,colony stimulating factor 2 (granuloc...	Mouse	HEK293 Cells
	GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01587.
TMPY-00816	GM-CSFR alpha Protein, Human, Recombinant (hFc) CSF2RAX,CSF2R,CD116,CSF2RY,GM-CSF-R-α,GM-CSF-R-alpha,GM-CSF ...	Human	HEK293 Cells
	GM-CSFR alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.2 kDa and the accession number is P15509-1.
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC...	Human	HEK293 Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF...
TMPJ-00091	G-CSF Protein, Mouse, Recombinant (His) Csf3,G-CSF,Granulocyte colony-stimulating factor,集落...	Mouse	HEK293 Cells
	Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of ...
TMPY-04421	FES Protein, Human, Recombinant (His & GST) FPS,FES proto-oncogene, tyrosine kinase	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and oneSH2 domain. FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. FES is observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-6. T...

重组蛋白

GM-CSF/CSF2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03713

Species: Rat

Expression System: HEK293 Cells

CD131 Protein, Human, Recombinant (His)

Cat.No: TMPY-01650

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant

Cat.No: TMPY-03858

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00750

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03662

Species: Mouse

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Mouse, Recombinant

Cat.No: TMPY-04114

Species: Mouse

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-01465

Species: Human

Expression System: E. coli

GM-CSFR alpha Protein, Human, Recombinant (His)

Cat.No: TMPY-01065

Species: Human

Expression System: HEK293 Cells

CD131 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04283

Species: Rat

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04036

Species: Rat

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05236

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02466

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03631

Species: Mouse

Expression System: HEK293 Cells

GM-CSFR alpha Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00816

Species: Human

Expression System: HEK293 Cells

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

Cat.No: TMPJ-01466

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00091

Species: Mouse

Expression System: HEK293 Cells

FES Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04421

Species: Human

Expression System: Baculovirus Insect Cells

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