MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.

Cat. No.	Product Name	CAS No.	Purity
T32208	Isogentisin 异龙胆黄素	491-64-5	98%
T32208	Isogentisin 是一种从龙胆科植物中分离出来的化合物，是一种用于预防吸烟引起的内皮损伤的新型化合物。Isogentisin 对单胺氧化酶具有抑制作用。
T10617	Brofaromine 化合物 T10617	63638-91-5	98%
T10617	Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate 化合物 TN3294	67667-71-4	98%
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone 化合物 TN2553	59443-02-6	98%
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate 化合物 TN3300	83182-58-5	98%
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
T10079	MAO-IN-1 化合物 T10079	124991-40-8	98%
T10079	MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
TN4137	Glicoricone 化合物 TN4137	161099-37-2	98%
TN4137	Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
T5470	LAZABEMIDE 拉扎贝胺	103878-84-8	98%
T5470	Lazabemide 是一种单胺氧化酶 B 的选择性的可逆抑制剂，但对 MAO-A 活性较低。它高浓度时具有抑制单胺摄取的作用，能够抑制去甲肾上腺素、血清素和多巴胺摄取，其IC50值分别为 86 μM、123 μM 和 >500 μM。它可用于研究帕金森和阿尔茨海默病。
T16770	Ro 41-1049 hydrochloride 化合物 T16770	127917-66-2	98%
T16770	Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
TN1099	Dihydroevocarpine 二氢吴茱萸卡品碱	15266-35-0	98%
TN1099	Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
TN2790	2'-O-Methylperlatolic acid 化合物 TN2790	38968-07-9	98%
TN2790	2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
TN3024	4'-Demethyleucomin 化合物 TN3024	34818-83-2	98%
TN3024
TN3918	Echitovenidine 化合物 TN3918	7222-35-7	98%
TN3918	Echitovenidine shows monoamine oxidase inhibitor activity.
TN3116	5-Hydroxy-1-methoxyxanthone 化合物 TN3116	27770-13-4	98%
TN3116	5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees o...
TN3726	Cudraflavone B 化合物 TN3726	19275-49-1	98%
TN3726	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
T15023	CX-157 化合物 T15023	205187-53-7	98%
T15023	CX-157 is a reversible monoamine oxidase-A (MAO-A) inhibitor (EC50:19.3 ng/mL).
T18918	Azure B 天青 B	531-55-5	98%
T18918	Azure B 是一种 Methylene blue 的主要代谢物，是一种阳离子染料，用于 Azure 曙红染色剂以进行血液涂片染色。它是高选择性和可逆的抑制单胺氧化酶(MAO)-A 的抑制剂，对重组人的 MAO-A 和 MAO-B 的IC50分别为 11 和 968 nM。它具有显著的抗抑郁作用。
T0391	Linezolid 雷奈佐利	165800-03-3	98%
T0391	Linezolid 是恶唑烷酮类合成抗生素，抑制细菌蛋白质合成的起始阶段，具有抗感染作用。
T0751	Furazolidone 呋喃唑酮	67-45-8	98%
T0751	Furazolidone 是一种具有抗菌和抗原虫活性的硝基呋喃衍生物，抑制AML1-ETO 转化细胞，IC50为12.7 μM。
T0369	Ethaverine hydrochloride 盐酸依沙维林	985-13-7	98%
T0369	Ethaverine hydrochloride 是罂粟碱的同系物。