pct

GlyH-101 是一种可渗透入细胞的 CFTR 阻断剂，Ki 为1.4 uM。

Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It also reduces the levels of PGE2 , PGD2 , and TXB2 in peritoneal exudates.

Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 via γ-glutamyl transpeptidase. PCTR2 is found in resolving mouse exudate and in both M1 and M2 macrophages differentiated from isolated human monocytes.

Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 and PCTR3 via peptidases. PCTR3 is found in infected mouse spleens and resolving exudate as well as isolated human spleen and septic plasma. It is also found in both M1 and M2 macrophages differentiated from isolated human monocytes.

QPCTL-IN-1 (compound 9) 是针对谷氨酰胺酰肽环转移酶样蛋白 (QPCTL) 的一种高效抑制剂，常被用于癌症研究领域。

p-SCN-Bn-PCTA (hydrochloride) 是一种双功能螯合剂 (Bifunctional Chelator; BFC)，属于大环 DTPA 衍生物，被用于肿瘤预靶向。它适用于多肽与放射性核素的偶联。

p-NH₂-Bn-PCTA (hydrochloride) 是一种双功能螯合剂 (Bifunctional Chelator; BFC)，属于用于肿瘤预靶向的大环 DPTA 衍生物，适用于多肽和放射性核素的偶联。

(S,R,S)-AHPC TFA (VHL ligand 1 TFA) 是一种 VH032-based VHL ligand，可用于募集 von Hippel-Lindau (VHL)蛋白。它能够利用 linker 与靶蛋白配体连接，形成 PROTAC 分子。

14:1 EPC trifluoromethanesulfonate是一种含有单不饱和14:1链的乙基磷脂酰胆碱(EPC)，具有转染活性，可用于活性分子输送。

DEPC-Treated Water 是一种经过高温高压灭菌处理的无核酸酶超纯水，能够防止非特异性核酸内切酶和核酸外切酶污染，并能确保 RNA 酶活性不受影响。

Btk inhibitor 1 Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.IC50 value:Target: BtkFrom PCT Int. Appl. (2012), WO 2012158843 A2 20121122. [1]. PCT Int. Appl. (2012), WO 2012158843 A2 20121122.

WUN40378 is compound first reported in PCT Int. Appl. (2019), WO 201909959, in which it was described as CBFβ-​RUNX1 inhibitor. WUN40378 is very similar to Ro 5-3335 but with an F instead of Cl. WUN40378 is also analog of Ro 24-7429. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https: www.medkoo.com page naming).