Tylophorine is a major alkaloid of Tylophora indica with anti-inflammatory and antitumor activity. Tylophorine arrests carcinoma cells at G1 phase by downregulating cyclin A2 expression.
Meliantriol is an active compound in Azadirachta indica (Neem). It can bind to PBP2A and PVL toxin with the binding energies of -6.02 kcal/mol and -8.94 kcal/mol, respectively.