folate receptor β

LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.

EC0489, Small molecule-drug conjugate (SMDC) ,a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor.

The peak excitation and emission wavelengths of EC-17 are 470/520 nm.EC-17 (disodium salt) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum.

L-Serine-S2-PEG-Formic acid 是用于连接 FGT-4 的分子。FGT-4 是一种 TLR7 激动剂，并且是靶向叶酸受体β (FR-β) 的嵌合物。

FGT-4 为叶酸受体 β (FR-β) 靶向的嵌合分子，且作为一种TLR7激动剂，促进M1巨噬细胞相关的iNOS和促炎症细胞因子IL-6的分泌，并增强细胞毒性CD8+ T细胞的增殖。在4T1乳腺癌小鼠模型中，FGT-4 显示抗肿瘤活性，可用于癌症免疫研究。