Name: Sodium benzoate
Brand: TargetMol
SKU: T8124
Price: 99 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

500 mg

¥ 163

In Stock

1 mL x 10 mM (in DMSO)

¥ 99

In Stock

产品介绍

生物活性

产品描述	Sodium benzoate (Benzoic acid sodium salt) is a D-Amino Acid Oxidase Inhibitor.Sodium Benzoate is a Food Preservative.
体外活性	At 24- and 48-hour. incubation time, sodium benzoate concentrations of 1.0, 1.5, and 2.0 mg/mL increased micronucleus formation when comparing with the control group (P < 0.05). At 24- and 48-hour. incubation time, sodium benzoate concentrations of 2.0 mg/mL increased chromosome break when comparing with the control group (P < 0.05). Sodium benzoate did not cause Ala40Thr (GCG→ACG) in superoxide dismutase gene. Sodium benzoate had the mutagenic and cytotoxic toxicity in lymphocytes caused by micronucleus formation and chromosome break[1].
体内活性	Sodium benzoate (NaB)?-treated rats spent less time in the open arm and had fewer entrances to the open arms in comparison with the control group (p<0.04). Also, the performance of the NaB-treated rats in fixed and accelerating speed rotarods was impaired, and the riding time (endurance) was lower than the control group (p<0.01)[2].
动物实验	The study was carried out between July and September 2012 in the Laboratory Animal Center of Shiraz University of Medical Sciences, Shiraz, Iran. The rats were divided into 2 groups receiving distilled water and sodium benzoate (NaB)? (200mg/kg/day). All the animals received daily gavages for 4 weeks. At the end of the fourth week, anxiety, and motor function were assessed in elevated plus maze and rotarod test[2]
别名	苯甲酸钠, Benzoic acid sodium salt

化学信息

分子量	144.10
分子式	C₇H₅NaO₂
CAS No.	532-32-1
Smiles	O=C([O-])c1ccccc1.[Na+]
密度	1.5 g/cm3. Temperature:20 °C.;1.5. Temperature:20 °C.

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 3.85 mg/mL (26.72 mM), Sonication is recommended.

H2O: 28.00 mg/mL (194.31 mM), Sonication is recommended.

溶液配制表

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	6.9396 mL	34.6981 mL	69.3963 mL	346.9813 mL
5 mM	1.3879 mL	6.9396 mL	13.8793 mL	69.3963 mL
10 mM	0.6940 mL	3.4698 mL	6.9396 mL	34.6981 mL
20 mM	0.3470 mL	1.7349 mL	3.4698 mL	17.3491 mL

H2O

	1mg	5mg	10mg	50mg
50 mM	0.1388 mL	0.6940 mL	1.3879 mL	6.9396 mL
100 mM	0.0694 mL	0.3470 mL	0.6940 mL	3.4698 mL

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments

一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent

DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH₂O，那么您的工作液浓度为 2 mg/mL 。

母液配置方法: 2 mg 药物溶于 50 μLDMSO TargetMol | reagent

（母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法: 取 50μLDMSO TargetMol | reagent

母液，添加 300 μLPEG300 TargetMol | reagent

混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH₂O TargetMol | reagent

混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300/ PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

Sodium benzoate

Sodium benzoate

产品介绍

计算器

体内实验配液计算器

剂量转换

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